Abstract:
:The absence of strategies to consistently and effectively address nonparoxysmal atrial fibrillation by nonpharmacological interventions has represented a long-standing treatment gap. A combined epicardial/endocardial ablation strategy, the hybrid Convergent procedure, was developed in response to this clinical need. A subxiphoid incision is used to access the pericardial space facilitating an epicardial ablation directed at isolation of the posterior wall of the left atrium. This is followed by an endocardial ablation to complete isolation of the pulmonary veins and for additional ablation as needed. Experience gained with the hybrid Convergent procedure during the last decade has led to the development and adoption of strategies to optimize the technique and mitigate risks. Additionally, a surgical and electrophysiology "team" approach including comprehensive training is believed critical to successfully develop the hybrid Convergent program. A recently completed randomized clinical trial indicated that this ablation strategy is superior to an endocardial-only approach for patients with persistent atrial fibrillation. In this review, we propose and describe best practice guidelines for hybrid Convergent ablation on the basis of a combination of published data, author consensus, and expert opinion. A summary of clinical outcomes, emerging evidence, and future perspectives is also given.
journal_name
Heart Rhythmjournal_title
Heart rhythmauthors
Makati KJ,Sood N,Lee LS,Yang F,Shults CC,DeLurgio DB,Melichercik J,Gill JS,Kaba RA,Ahsan S,Weerasooriya R,Joshi P,Lellouche N,Blaauw Y,Zannis K,Sebag FA,Gauri A,Zembala MO,Tondo C,Steinberg JSdoi
10.1016/j.hrthm.2020.10.004subject
Has Abstractpub_date
2020-10-09 00:00:00eissn
1547-5271issn
1556-3871pii
S1547-5271(20)30945-0pub_type
杂志文章相关文献
HEART RHYTHM文献大全abstract:BACKGROUND:Mutations in the RyR2-encoded cardiac ryanodine receptor/calcium release channel and in CASQ2-encoded calsequestrin cause catecholaminergic polymorphic ventricular tachycardia (CPVT1 and CPVT2, respectively). OBJECTIVES:The purpose of this study was to evaluate the extent of genotypic and phenotypic heterog...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2006.03.025
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Verification of bidirectional block is important for mitral isthmus (MI) ablation. However, recurrent perimitral reentry exists despite apparently MI block. OBJECTIVE:The purpose of this study was to identify and investigate the characteristics of the ridge breakthrough despite apparent bidirectional MI blo...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2016.06.018
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:High-intensity frequency ultrasound (HIFU) can achieve pulmonary vein isolation (PVI), but severe complications have happened. An esophageal temperature (ET)-guided safety algorithm was implemented. We investigated medium-term outcome. METHODS:After left atrial access, HIFU was applied until c...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2011.09.072
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Implantable cardioverter-defibrillators (ICDs) are underutilized in Asia, Latin America, Eastern Europe, the Middle East, and Africa. The Improve SCA Study is the largest prospective study to evaluate the benefit of ICD therapy in underrepresented geographies. This analysis reports the primary objective of t...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2019.09.023
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:In observational studies, case reports, and animal studies, amiodarone has been associated with incident cancer. OBJECTIVE:The purpose of this study was to examine whether a dose-response relationship between amiodarone use and the risk of cancer could be ascertained in a large nationwide study cohort. MET...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2019.11.025
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Different P-wave morphologies during sinus rhythm as displayed on standard ECGs have been postulated to correspond to differences in interatrial conduction. OBJECTIVE:The purpose of this study was to evaluate the hypothesis by comparing P-wave morphologies using left atrial activation maps. METHODS:Twenty-...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2007.12.017
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Patients with heart failure and sleep apnea are at increased risk for developing arrhythmias. Whether treatment of sleep apnea reduces arrhythmias is unknown. OBJECTIVE:The purpose of this study was to determine whether adaptive servo-ventilation (ASV) with optimal medical therapy (OMT) reduces atrial fibri...
journal_title:Heart rhythm
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.hrthm.2018.07.027
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Cardiac resynchronization therapy (CRT) and atrial ablation procedures currently lack a noninvasive imaging modality for reliable treatment planning and monitoring. Electromechanical wave imaging (EWI) is an ultrasound-based method that has previously been shown to be capable of noninvasively and transmurall...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2013.02.028
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Carvedilol and its analogues suppress delayed afterdepolarizations (DADs) and catecholaminergic polymorphic ventricular tachycardias by direct action on the cardiac ryanodine receptor type 2 (RyR2). OBJECTIVE:To test a hypothesis that carvedilol analogue may also prevent triggered activities (TAs) through t...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2012.09.006
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Catheter ablation is less successful for treatment of persistent atrial fibrillation (PersAF) than for paroxysmal atrial fibrillation. Some studies suggest that left atrial appendage (LAA) isolation in addition to pulmonary vein isolation (PVI) is required to maximize the benefits for PersAF after ablation. ...
journal_title:Heart rhythm
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.hrthm.2016.05.012
更新日期:2016-09-01 00:00:00
abstract::Cardiac arrhythmia surgery was initiated in 1968 with the first successful division of an accessory AV connection for the Wolff-Parkinson-White Syndrome. Subsequent surgical procedures included the left atrial isolation procedure and the right atrial isolation procedure for automatic atrial tachycardias, discrete cryo...
journal_title:Heart rhythm
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.hrthm.2004.10.021
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Implantable cardioverter-defibrillators monitor intracardiac electrograms (EGMs) to discriminate between ventricular and supraventricular tachycardias. The incidence of inappropriate shocks remains high because of misclassification of the tachycardia in an otherwise hemodynamically stable individual. Couplin...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2014.06.034
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Ventricular tachyarrhythmias are an important cause of morbidity and mortality in cardiac sarcoidosis. To date, the prevalence and incidence of ventricular tachycardia/ventricular fibrillation (VT/VF) in this population remain unknown. OBJECTIVES:To determine the prevalence and incidence of ventricular tach...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2012.02.010
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Enhanced dispersion of action potential duration (APD) is a major contributor to long QT syndrome (LQTS)-related arrhythmias. OBJECTIVE:To investigate spatial correlations of regional heterogeneities in cardiac repolarization and mechanical function in LQTS. METHODS:Female transgenic LQTS type 2 (LQT2; n =...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2013.07.038
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Myocardial fibrosis (macroscopic scar or diffuse reactive fibrosis) is one of the determinants of impaired left ventricular (LV) global longitudinal strain (GLS) in heart failure (HF) patients. OBJECTIVE:The purpose of this study was to evaluate the prognostic value of LV GLS in HF patients treated with car...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2018.03.034
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:The ionic mechanisms underlying action potential duration alternans are not established. OBJECTIVES:The purpose of this study was to explore the mechanisms underlying action potential alternans. METHODS:Computer simulations were performed using a model of a single ischemic myocyte. To emulate ischemia, ext...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2005.11.016
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Percutaneous left atrial appendage closure (pLAAC) emerged as an option for stroke prevention in patients with atrial fibrillation ineligible for long-term anticoagulation. Real-world data on pLAAC's in-hospital and 30-day readmission measures are limited. OBJECTIVE:We sought to report the nationwide incide...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2019.09.018
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to test the hypothesis that on the epicardium of the in vivo human heart, ventricular fibrillation (VF) consists of chaotic small wavefronts that constantly change paths. BACKGROUND:Despite the significance of VF to cardiovascular mortality, little is known about the wavefront...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2004.01.007
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Because device-related thrombus (DRT) portends a poor prognosis after left atrial appendage closure with the Watchman device, surveillance transesophageal echocardiography (TEE) is recommended at 45 days and 1 year. However, oral anticoagulants are just discontinued at 45 days, rendering this early TEE unlik...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2020.06.024
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Ventricular arrhythmias (VAs) in cardiac sarcoidosis (CS) are frequently refractory to both antiarrhythmic drug (AAD) therapy and catheter ablation (CA). Cardiac sympathetic denervation (CSD) has been shown to reduce VA burden and implantable cardioverter-defibrillator (ICD) shocks in patients with nonischem...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2019.02.025
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:The mechanisms of persistent human atrial fibrillation (AF) are not well understood. OBJECTIVE:The purpose of this study was to examine whether left atrial (LA) drivers are present in persistent AF by performing a comprehensive evaluation of atrial activation frequency and organization using multisite atria...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2008.01.027
更新日期:2008-05-01 00:00:00
abstract::Pregnancy is a period of increased cardiovascular risk in a woman's life. In the setting of an inherited arrhythmia syndrome (IAS), cardiologists and obstetricians may be unfamiliar with cardiovascular optimization and risk stratification in pregnancy. Historically, there were little data addressing the safety of preg...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2019.08.004
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Right ventricular myocardial pacing leads to nonphysiological activation of heart ventricles. Contrary to this, His bundle pacing preserves their fast activation. Ultra-high-frequency electrocardiography (UHF-ECG) is a novel tool for ventricular depolarization assessment. OBJECTIVE:The purpose of this study...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2019.11.016
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:The optimal energy setting for endoscopic pulmonary vein (PV) isolation (PVI) has not yet been determined. OBJECTIVE:To assess the influence of varying energy settings on the efficacy and safety of endoscopic PVI. METHODS:In the current prospective study, 30 patients with paroxysmal atrial fibrillation wer...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2012.03.059
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Left atrial (LA) low-voltage areas (LVAs) are frequently observed in patients with atrial fibrillation (AF) and may predict AF recurrence after catheter ablation. OBJECTIVE:The aim of this study was to develop and validate a clinical tool to identify LVAs that are associated with AF recurrence after pulmona...
journal_title:Heart rhythm
pub_type: 杂志文章,多中心研究
doi:10.1016/j.hrthm.2015.07.003
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:In patients with ventricular tachycardia or ventricular fibrillation (VT/VF) electrical storm (ES) undergoing catheter ablation (CA), hypotension due to refractory VT/VF, use of anesthesia, and cardiac stunning due to repeated implantable cardioverter-defibrillator shocks might precipitate acute hemodynamic ...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2017.09.005
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Effective chest compressions during prolonged ventricular fibrillation (VF) have been shown to increase the chances of successful defibrillation to a rhythm associated with a sustainable cardiac output. There is currently no effective method of recording the degree of antegrade coronary artery flow during ch...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2010.12.033
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:The occurrence of congestive heart failure (CHF) hospitalization among patients with atrial fibrillation (AF) is a poor prognostic marker. OBJECTIVE:The purpose of this study was to assess whether insulin-like growth factor-binding protein 7 (IGFBP-7), a marker of myocardial damage, identifies AF patients a...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2020.11.028
更新日期:2020-12-03 00:00:00
abstract:BACKGROUND:The apamin-sensitive small-conductance calcium-activated K (SK) current IKAS modulates automaticity of the sinus node. IKAS blockade by apamin causes sinus bradycardia. OBJECTIVE:The purpose of this study was to test the hypothesis that IKAS modulates ventricular automaticity. METHODS:We tested the effects...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2018.10.033
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Ventricular tachycardia (VT) in patients with idiopathic dilated cardiomyopathy often originates from the basal left ventricular myocardium and also can originate from the conduction system. The basal left ventricular myocardium reaches to the base of the aortic sinus cusps. OBJECTIVE:The purpose of this st...
journal_title:Heart rhythm
pub_type: 杂志文章
doi:10.1016/j.hrthm.2010.10.045
更新日期:2011-03-01 00:00:00