Extralobar pulmonary sequestration with elevated serum neuron-specific enolase: A case report and review of the literature.

Abstract:

RATIONALE:Pulmonary sequestration (PS) presenting with elevated serum tumor markers is rare, and it might be misdiagnosed as malignancy. PATIENT CONCERNS:A 26-year-old asymptomatic male patient was admitted because the x-ray showed an intrathoracic lesion. Meanwhile, the serum neuron-specific enolase (NSE) was elevated. Three-dimensional computed tomography angiography revealed an isolated feeding vessel arising from the aorta. DIAGNOSES:Extralobular PS was confirmed by computed tomography angiography and postoperative pathological staining. INTERVENTIONS:Two-port thoracoscopic resection of the sequestrated lobe was performed. OUTCOMES:The serum NSE decreased to within the normal range and persisted during the follow up of 10 months. LESSONS:A thorough work-up should be considered for the PS patients presenting with abnormal serum NSE. Detailed knowledge regarding the relationship between NSE and PS necessitates further studies.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Kong FW,Wang WM,Gong L,Wu W,Zhang M

doi

10.1097/MD.0000000000022574

subject

Has Abstract

pub_date

2020-10-02 00:00:00

pages

e22574

issue

40

eissn

0025-7974

issn

1536-5964

pii

00005792-202010020-00092

journal_volume

99

pub_type

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