Abstract：
:Clonidine is a central alpha-2 agonist well known to produce a syndrome of bradycardia and hypotension in overdose. However, few examples of overt clinical clonidine toxicity secondary to cutaneous absorption have been reported. We report a case of unintentional systemic clonidine toxicity in an adult because of a compounded preparation of clonidine applied to a degraded skin barrier. A 35-year-old male suffered a motorcycle accident 48 hours before presentation resulting in an abrasion to his distal left leg. On the day of presentation, he self-treated the wound by repeated application of a family member's pain-relieving cream. Later he was found confused and unable to stand by a family member. The family member recognized the thick visible coat of cream as the likely cause and decontaminated the patient while calling 911. Prehospital vitals were notable for a blood pressure of 80/30 mm Hg and heart rate of 38 beats per minute. In the emergency department, the patient was resuscitated with intravenous fluids with resultant normalization of blood pressure. Upon later review, the cream was determined to have been created by a local compounding pharmacy for the use in neuropathic pain and was labeled to contain clonidine, lidocaine, ketamine, and gabapentin. Cutaneous absorption of the pain cream was greatly increased because of loss of skin integrity. Military physicians and compounding pharmacies should ensure that patients are aware of the proper application of compounded creams and the potential risk for systemic toxicity with overuse or degraded skin.
journal_name
Mil Medjournal_title
Military medicineauthors
Downs JW,Cumpston KLdoi
10.1093/milmed/usaa284subject
Has Abstractpub_date
2020-10-02 00:00:00eissn
0026-4075issn
1930-613Xpii
5909710pub_type
杂志文章abstract：UNLABELLED:U.S. Marines perform mission tasks under heavy loads which may compromise performance of combat tasks. However, data supporting this performance decrement are limited. PURPOSE:The aim of this study was to determine the effects of load on performance of combat-related tasks. METHODS:Subjects (N=18) ran a mo...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/MILMED-D-14-00432
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVES:To determine the outcomes scores of military patients who initially present with a variety of shoulder conditions, identify which scores demonstrate the highest correlation per diagnosis, and determine if a difference exists for patients who went onto surgery. METHODS:Two-hundred and seventy five consecutiv...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed-d-11-00234
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:Current military operations in the Middle East involve active duty, National Guard, and reserve troops from all services. Despite common misconceptions, the desert environment in this region has significant aeroallergen seasons that may exacerbate allergic rhinitis. OBJECTIVE:To review perennial and seasona...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed.170.12.1026
更新日期：2005-12-01 00:00:00
abstract：:Gingival diseases are the most widely dispersed diseases in the United States. In some patients, periodontal disease appears in a generalized form, but more often it appears in localized areas. Furthermore, after treatment with scaling and root planing in generalized cases, the disease is often reduced to a few local ...
journal_title：Military medicine
pub_type： 杂志文章,评审
doi：
更新日期：2001-11-01 00:00:00
abstract：:A study of ambulatory mental health services on a U.S. Army post where logistic support personnel are stationed compared utilization of psychiatric services before, during, and after the Persian Gulf War. Rates were calculated for service utilization for the at-risk groups from consecutive cases presenting at the post...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:The U.S. Army Special Forces Medic, Military Occupational Specialty 18D, is a unique, enlisted, medical asset. The training of the 18D is demanding, lengthy, and selective. The 18D is trained to independently assess, and provide acute and long-term medical care for, a variety of medical conditions in support of the Sp...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：INTRODUCTION:With more than 370,000 military and civilian personnel stationed across Pacific Command (PACOM), medical evacuation in this largest command presents unique challenges. The authors describe medical evacuations analyzed from the U.S. Air Force Transportation Command Regulating and Command & Control Evacuatio...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.1093/milmed/usaa289
更新日期：2020-11-21 00:00:00
abstract：PURPOSE:Alpha-blockers and calcium channel blockers have shown promise for medical expulsion therapy (MET) of distal ureteral calculi < 1 cm in size. Although MET has been discussed in urology for some time, little has been written about MET in the emergency medicine and primary care literature. We sought to evaluate c...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed-d-10-00100
更新日期：2010-11-01 00:00:00
abstract：:Hip fractures in the young are exceedingly rare and are usually seen in instances of high energy trauma or metabolically altered bone states. In this case report, we present an occult femoral neck fracture, diagnosed by magnetic resonance imaging, in an otherwise healthy, young, active duty male patient with an isolat...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed-d-11-00321
更新日期：2012-05-01 00:00:00
abstract：:The massive Department of Defense deployment in support of Hurricane Andrew relief cast the military medical departments in a new role. Military medical personnel were challenged to apply the traditional principles of combat medicine to a noncombat environment, within the continental United States, within an existing ...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:The combined effects of injury from exposure to ionizing radiation and the potential biological warfare agent Venezuelan equine encephalitis (VEE) virus remain largely unknown. To study these effects, 4- to 5-week-old B6D2F1/J female mice were given a sublethal whole-body 7 Gy dose of 60Co gamma-photon radiation follo...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：INTRODUCTION:The objective was to determine if the Mobile Device Outcomes-based Rehabilitation Program (MDORP) improved strength, mobility, and gait quality in service members (SMs) and Veterans with lower limb amputation (LLA). METHODS:Seven SMs and 10 Veterans with LLA enrolled and were trained to use a mobile senso...
journal_title：Military medicine
pub_type： 杂志文章,多中心研究
doi：10.1093/milmed/usz201
更新日期：2020-01-07 00:00:00
abstract：:We utilize a mixed methods approach to provide three new, separate analyses as part of the development of the next aeromedical evacuation (MEDEVAC) platform of the Future of Vertical Lift (FVL) program. The research questions follow: RQ1) What are the optimal capabilities of a FVL MEDEVAC platform given an Afghanistan...
journal_title：Military medicine
pub_type： 杂志文章,评审
doi：10.7205/MILMED-D-12-00370
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:Cervical radiculopathy is a common disorder that portends significant morbidity. The presence of radiculopathy can have a debilitating effect on patients as well as a significant economic impact. Active duty military patients with increased physical occupational demands can be significantly impacted by cervi...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/MILMED-D-16-00085
更新日期：2017-03-01 00:00:00
abstract：INTRODUCTION:Repetitive transcranial magnetic stimulation (rTMS) as a treatment for depression has been studied for over two decades. Repetitive TMS was approved by the Food and Drug Administration in 2008 for the treatment of depression after at least one failed trial of an antidepressant medication of adequate dose a...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.1093/milmed/usaa148
更新日期：2020-09-18 00:00:00
abstract：:Rhabdomyolysis is a painful and potentially life-threatening injury in which muscle breaks down in response to an insult. In this case report, we describe the clinical course of a 22-year-old man who developed paraspinal muscle rhabdomyolysis and possible compartment syndrome in association with strenuous activity and...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/MILMED-D-14-00647
更新日期：2015-07-01 00:00:00
abstract：:Administrative and clinical considerations for the establishment of an ophthalmic laser program at a VA Outpatient Clinic are discussed. Outcomes of the first 320 patients treated over a 3-year period of time are presented. The program is evaluated from the perspectives of patient care, safety, maintenance, education,...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：INTRODUCTION:Respiratory tract infections (RTI), such as those caused by influenza viruses and, more recently, the severe acute respiratory syndrome coronavirus-2, pose a significant burden to military health care systems and force readiness. The gut microbiota influences immune function, is malleable, and may provide ...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.1093/milmed/usaa261
更新日期：2020-11-02 00:00:00
abstract：:Genus Candida covers more than 50 species, half of which can cause infections in humans. Some of the Candida species exhibit drug resistance; therefore, there is an urgent need for rapid and accurate differentiation for rendering appropriate and effective management. Here, we report a new methodology employing real-ti...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/MILMED-D-14-00294
更新日期：2015-06-01 00:00:00
abstract：:Aristotle saw that the striving of humanity was toward being well - a physical, mental and spiritual state where life flourished. A contemporary definition of health recognizes that disease and disability can and often do co-exist with wellness. In this new conception, health is transformed from a state that requires ...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.1093/milmed/usy213
更新日期：2018-11-01 00:00:00
abstract：Objectives:Greater serum levels and dietary intake of vitamin D have been inversely associated with the risk of multiple cancers including colon cancer. Most colorectal cancers are thought to arise from adenomatous polyps, which become dysplastic under the influence of numerous factors. Prospective data are needed to d...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.1093/milmed/usx152
更新日期：2018-03-01 00:00:00
abstract：:Personality characteristics associated with successful adaptation to military life are often described in gender-related terms. However, valid, reliable measures of gender-related personality characteristics have not been established for military populations. The purpose of this study was to validate an instrument for...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Advanced practice nurses (APN) who practice in the surgical subspecialty areas may have the opportunity to expand their scope of practice to include first assistant at surgery. Surgical APNs who practice as registered nurse first assistants (RNFA) should seek credentialing and apply for institutional privileges to ass...
journal_title：Military medicine
pub_type： 历史文章,杂志文章
doi：10.7205/milmed.171.9.875
更新日期：2006-09-01 00:00:00
abstract：:The rules governing armed conflict are numerous and in many respects complex. In areas that are very complex, experts such as lawyers may be called in to assist, especially in the planning of military action. But the nature and tempo of warfare rarely allows a person in the field to enjoy such a luxury. Therefore, eve...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：2002-08-01 00:00:00
abstract：INTRODUCTION:Occupational noise threatens U.S. worker health and safety and commands a significant financial burden on state and federal government worker compensation programs. Previous studies suggest that hearing conservation programs have contributed to reduced occupational hearing loss for noise-exposed workers. M...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.1093/milmed/usx112
更新日期：2018-09-01 00:00:00
abstract：Introduction:Many service members experiencing symptoms of mental health conditions do not receive mental health care for these symptoms. The stigma associated with having a mental health condition or seeking treatment is often cited as a specific barrier to mental health care. However, study results bearing on the que...
journal_title：Military medicine
pub_type： 杂志文章,评审
doi：10.1093/milmed/usx219
更新日期：2018-11-01 00:00:00
abstract：:This paper describes issues in the psychological assessment of individuals for security clearances, special duty, and sensitive positions. Using assessment for access to sensitive compartmented information as an example, the paper identifies, and explicates problems in criterion validity (the NEXUS issue), practical a...
journal_title：Military medicine
pub_type： 杂志文章,评审
doi：
更新日期：1993-09-01 00:00:00
abstract：UNLABELLED:Complementary and alternative medicine (CAM) is a growing component of medicine within the U.S. civilian and military populations. Tripler Army Medical Center (TAMC) Family Medicine Clinic represents an overseas medical facility stationed among a diverse ethnic population. The impact that local cultures have...
journal_title：Military medicine
pub_type： 杂志文章
doi：10.7205/milmed-d-09-00077
更新日期：2010-07-01 00:00:00
abstract：:Symptoms of vaginitis and urinary tract infections are miserable, distracting, and significantly affect women's quality of life. Among civilian women, these symptoms account for 10.5 million office visits per year. To examine the scope of the problem for military women during deployment situations, surveys were sent t...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：:This study seeks to investigate the mortality rates of U.K. servicemen with postcombat syndromes following the Boer War and World War I. Random samples of veterans awarded war pensions for either disordered action of the heart (DAH) or neurasthenia/shellshock were compared with gunshot wounded ex-servicemen as control...
journal_title：Military medicine
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
