Deep Learning for Hemorrhagic Lesion Detection and Segmentation on Brain CT Images.

Abstract:

:Stroke is an acute cerebral vascular disease that is likely to cause long-term disabilities and death. Immediate emergency care with accurate diagnosis of computed tomographic (CT) images is crucial for dealing with a hemorrhagic stroke. However, due to the high variability of a stroke's location, contrast, and shape, it is challenging and time-consuming even for experienced radiologists to locate them. In this paper, we propose a U-net based deep learning framework to automatically detect and segment hemorrhage strokes in CT brain images. The input of the network is built by concatenating the flipped image with the original CT slice which introduces symmetry constraints of the brain images into the proposed model. This enhances the contrast between hemorrhagic areas and normal brain tissue. Various Deep Learning topologies are compared by varying the layers, batch normalization, dilation rates, and pre-train models. This could increase the respective filed and preserves more information on lesion characteristics. Besides, the adversarial training is also adopted in the proposed network to improve the accuracy of the segmentation. The proposed model is trained and evaluated on two different datasets, which achieve the competitive performance with human experts with the highest location accuracy 0.9859 for detection, 0.8033 Dice score, and 0.6919 IoU for segmentation. The results demonstrate the effectiveness, robustness, and advantages of the proposed deep learning model in automatically hemorrhage lesion diagnosis, which make it possible to be a clinical decision support tool in stroke diagnosis.

authors

Li L,Wei M,Liu B,Atchaneeyasakul K,Zhou F,Pan Z,Kumar S,Zhang J,Pu Y,Liebeskind DS,Scalzo F

doi

10.1109/JBHI.2020.3028243

subject

Has Abstract

pub_date

2020-10-01 00:00:00

eissn

2168-2194

issn

2168-2208

journal_volume

PP

pub_type

杂志文章
  • Network-based modeling and intelligent data mining of social media for improving care.

    abstract::Intelligently extracting knowledge from social media has recently attracted great interest from the Biomedical and Health Informatics community to simultaneously improve healthcare outcomes and reduce costs using consumer-generated opinion. We propose a two-step analysis framework that focuses on positive and negative...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2014.2336251

    authors: Akay A,Dragomir A,Erlandsson BE

    更新日期:2015-01-01 00:00:00

  • Joint Feature Extraction and Classifier Design for ECG-Based Biometric Recognition.

    abstract::Traditional biometric recognition systems often utilize physiological traits such as fingerprint, face, iris, etc. Recent years have seen a growing interest in electrocardiogram (ECG)-based biometric recognition techniques, especially in the field of clinical medicine. In existing ECG-based biometric recognition metho...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2015.2402199

    authors: Gutta S,Cheng Q

    更新日期:2016-03-01 00:00:00

  • Vein visualization using a smart phone with multispectral Wiener estimation for point-of-care applications.

    abstract::Effective vein visualization is clinically important for various point-of-care applications, such as needle insertion. It can be achieved by utilizing ultrasound imaging or by applying infrared laser excitation and monitoring its absorption. However, while these approaches can be used for vein visualization, they are ...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2014.2313145

    authors: Song JH,Kim C,Yoo Y

    更新日期:2015-03-01 00:00:00

  • An innovative nonintrusive driver assistance system for vital signal monitoring.

    abstract::This paper describes an in-vehicle nonintrusive biopotential measurement system for driver health monitoring and fatigue detection. Previous research has found that the physiological signals including eye features, electrocardiography (ECG), electroencephalography (EEG) and their secondary parameters such as heart rat...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2014.2305403

    authors: Sun Y,Yu XB

    更新日期:2014-11-01 00:00:00

  • Classification of Opioid Usage Through Semi-Supervised Learning for Total Joint Replacement Patients.

    abstract::Opioid misuse and overdose have become a public health hazard and caused drug addiction and death in the United States due to rapid increase in prescribed and non-prescribed opioid usage. The misuse and overdose are highly related to opioid over-prescription for chronic and acute pain treatment, where a one-size-fits-...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2020.2992973

    authors: Lee S,Wei S,White V,Bain PA,Baker C,Li J

    更新日期:2021-01-01 00:00:00

  • Toward a Wirelessly Powered On-Lens Intraocular Pressure Monitoring System.

    abstract::This paper presents a wireless on-lens intraocular pressure monitoring system, comprising a capacitance-to-digital converter and a wirelessly powered radio-frequency identification (RFID)-compatible communication system, for sensor control and data communication. The capacitive sensor was embedded on a soft contact le...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2016.2594058

    authors: Chiou JC,Hsu SH,Liao YT,Huang YC,Yeh GT,Kuei CK,Dai KS

    更新日期:2016-09-01 00:00:00

  • DBN-Extended: A Dynamic Bayesian Network Model Extended With Temporal Abstractions for Coronary Heart Disease Prognosis.

    abstract::Dynamic Bayesian networks (DBNs) are temporal probabilistic graphical models that model temporal events and their causal and temporal dependencies. Temporal abstraction (TA) is a knowledge-based process that abstracts raw temporal data into higher level interval-based concepts. In this paper, we present an extended DB...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2015.2420534

    authors: Orphanou K,Stassopoulou A,Keravnou E

    更新日期:2016-05-01 00:00:00

  • Objective study of sensor relevance for automatic cough detection.

    abstract::The development of a system for the automatic, objective, and reliable detection of cough events is a need underlined by the medical literature for years. The benefit of such a tool is clear as it would allow the assessment of pathology severity in chronic cough diseases. Even though some approaches have recently repo...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/jbhi.2013.2239303

    authors: Drugman T,Urbain J,Bauwens N,Chessini R,Valderrama C,Lebecque P,Dutoit T

    更新日期:2013-05-01 00:00:00

  • 40-Hz ASSR for Measuring Depth of Anaesthesia During Induction Phase.

    abstract::This paper proposes an anaesthesia monitoring system that accurately measures the depth of anaesthesia through 40-Hz auditory steady-state response. With accurate and fast depth of anaesthesia measuring, the monitor can reduce the incidence of awareness during surgical operation. The proposed denoising method for extr...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2017.2778140

    authors: Haghighi SJ,Komeili M,Hatzinakos D,Beheiry HE

    更新日期:2018-11-01 00:00:00

  • Contribution of a Trunk Accelerometer System to the Characterization of Gait in Patients With Mild-to-Moderate Parkinson's Disease.

    abstract:OBJECTIVE:Gait disturbances like shuffling and short steps are obvious at visual observation in patients with advanced Parkinson's disease (PD). However, quantitative methods are increasingly used to evaluate the wide range of gait abnormalities that may occur over the disease course. The goal of this study was to test...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2015.2469540

    authors: Demonceau M,Donneau AF,Croisier JL,Skawiniak E,Boutaayamou M,Maquet D,Garraux G

    更新日期:2015-11-01 00:00:00

  • Performance Analysis of Gyroscope and Accelerometer Sensors for Seismocardiography-Based Wearable Pre-Ejection Period Estimation.

    abstract:OBJECTIVE:Systolic time intervals, such as the pre-ejection period (PEP), are important parameters for assessing cardiac contractility that can be measured non-invasively using seismocardiography (SCG). Recent studies have shown that specific points on accelerometer- and gyroscope-based SCG signals can be used for PEP ...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2019.2895775

    authors: Shandhi MMH,Semiz B,Hersek S,Goller N,Ayazi F,Inan OT

    更新日期:2019-11-01 00:00:00

  • A Patient-Centric Health Information Exchange Framework Using Blockchain Technology.

    abstract::Health Information Exchange (HIE) exhibits remarkable benefits for patient care such as improving healthcare quality and expediting coordinated care. The Office of the National Coordinator (ONC) for Health Information Technology is seeking patient-centric HIE designs that shift data ownership from providers to patient...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2020.2993072

    authors: Zhuang Y,Sheets LR,Chen YW,Shae ZY,Tsai JJP,Shyu CR

    更新日期:2020-08-01 00:00:00

  • Detecting Suspected Pump Thrombosis in Left Ventricular Assist Devices via Acoustic Analysis.

    abstract:OBJECTIVE:Left ventricular assist devices (LVADs) fail in up to 10% of patients due to the development of pump thrombosis. Remote monitoring of patients with LVADs can enable early detection and, subsequently, treatment and prevention of pump thrombosis. We assessed whether acoustical signals measured on the chest of p...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2020.2966178

    authors: Semiz B,Hersek S,Pouyan MB,Partida C,Blazquez-Arroyo L,Selby V,Wieselthaler G,Rehg JM,Klein L,Inan OT

    更新日期:2020-07-01 00:00:00

  • User independent estimations of gait events with minimal sensor data.

    abstract:GOAL:The purpose of this study was to provide an initial examination of the utility of the Beta Process - Auto Regressive - Hidden Markov Model (BP-AR-HMM) for the prior identification of gait events. A secondary objective was to determine whether the output of the model could be used for classification and prediction ...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2020.3028827

    authors: Donahue S,Jin L,Hahn M

    更新日期:2020-10-05 00:00:00

  • Compressed sensing technology-based spectral estimation of heart rate variability using the integral pulse frequency modulation model.

    abstract::In this paper, a compressed sensing (CS)-based spectral estimation of heart rate variability (HRV) using the integral pulse frequency modulation (IPFM) model is introduced. Previous research in the literature indicated that the IPFM model is widely accepted as a functional description of the cardiac pacemaker, and thu...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2013.2282307

    authors: Chen SW,Chao SC

    更新日期:2014-05-01 00:00:00

  • Sleep Period Time Estimation Based on Electrodermal Activity.

    abstract::We proposed and tested a method to estimate sleep period time (SPT) using electrodermal activity (EDA) signals. Eight healthy subjects and six obstructive sleep apnea patients participated in the experiments. Each subject's EDA signals were measured at the middle and ring fingers of the dominant hand during polysomnog...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2015.2490480

    authors: Hwang SH,Seo S,Yoon HN,Jung DW,Baek HJ,Cho J,Choi JW,Lee YJ,Jeong DU,Park KS

    更新日期:2017-01-01 00:00:00

  • Statistical Metamodeling and Sequential Design of Computer Experiments to Model Glyco-Altered Gating of Sodium Channels in Cardiac Myocytes.

    abstract::Glycan structures account for up to 35% of the mass of cardiac sodium ( Nav ) channels. To question whether and how reduced sialylation affects Nav activity and cardiac electrical signaling, we conducted a series of in vitro experiments on ventricular apex myocytes under two different glycosylation conditions, reduced...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2015.2458791

    authors: Du D,Yang H,Ednie AR,Bennett ES

    更新日期:2016-09-01 00:00:00

  • A Deep Convolutional Neural Network-Based Framework for Automatic Fetal Facial Standard Plane Recognition.

    abstract::Ultrasound imaging has become a prevalent examination method in prenatal diagnosis. Accurate acquisition of fetal facial standard plane (FFSP) is the most important precondition for subsequent diagnosis and measurement. In the past few years, considerable effort has been devoted to FFSP recognition using various hand-...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2017.2705031

    authors: Yu Z,Tan EL,Ni D,Qin J,Chen S,Li S,Lei B,Wang T

    更新日期:2018-05-01 00:00:00

  • Coronary vein extraction in MSCT volumes using minimum cost path and geometrical moments.

    abstract::This work deals with the extraction of patient-specific coronary venous anatomy in preoperative multislice computed tomography (MSCT) volumes. A hybrid approach has been specifically designed for low-contrast vascular structure detection. It makes use of a minimum cost path technique with a Fast-Marching front propaga...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2013.2245420

    authors: Garcia MP,Velut J,Boulmier D,Leclercq C,Garreau M,Haigron P,Toumoulin C

    更新日期:2013-03-01 00:00:00

  • Inverse estimation of multiple muscle activations from joint moment with muscle synergy extraction.

    abstract::Human movement is produced resulting from synergetic combinations of multiple muscle contractions. The resultant joint movement can be estimated through the related multiple-muscle activities, which is formulated as the forward problem. Neuroprosthetic applications may benefit from cocontraction of agonist and antagon...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章,随机对照试验

    doi:10.1109/JBHI.2014.2342274

    authors: Li Z,Guiraud D,Hayashibe M

    更新日期:2015-01-01 00:00:00

  • A novel and lightweight system to secure wireless medical sensor networks.

    abstract::Wireless medical sensor networks (MSNs) are a key enabling technology in e-healthcare that allows the data of a patient's vital body parameters to be collected by the wearable or implantable biosensors. However, the security and privacy protection of the collected data is a major unsolved issue, with challenges coming...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2013.2268897

    authors: He D,Chan S,Tang S

    更新日期:2014-01-01 00:00:00

  • Assessment of Signal Processing Methods for Measuring the Respiratory Rate in the Neonatal Intensive Care Unit.

    abstract::Knowledge of the pathological instabilities in the breathing pattern can provide valuable insights into the cardiorespiratory status of the critically-ill infant as well as their maturation level. This paper is concerned with the measurement of respiratory rate in premature infants. We compare the rates estimated from...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2019.2898273

    authors: Jorge J,Villarroel M,Chaichulee S,Green G,McCormick K,Tarassenko L

    更新日期:2019-11-01 00:00:00

  • Bi-Frequency Symmetry Difference EIT-Feasibility and Limitations of Application to Stroke Diagnosis.

    abstract:OBJECTIVE:Bi-Frequency Symmetry Difference (BFSD)-EIT can detect, localize and identify unilateral perturbations in symmetric scenes. Here, we test the viability and robustness of BFSD-EIT in stroke diagnosis. METHODS:A realistic 4-layer Finite Element Method (FEM) head model with and without bleed and clot lesions is...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2019.2960862

    authors: McDermott B,O'Halloran M,Avery J,Porter E

    更新日期:2020-08-01 00:00:00

  • Investigating the Correlation of Ktrans With Semi-Quantitative MRI Parameters Towards More Robust and Reproducible Perfusion Imaging Biomarkers in Three Cancer Types.

    abstract::MRI Imaging biomarkers (IBs) have the potential to deliver quantitative cancer descriptors of pathophysiology for non-invasively screening, diagnosing, and monitoring cancer patients across the cancer continuum. Despite a worldwide effort to standardize IBs involving major cancer organizations, significant variability...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2018.2888979

    authors: Ioannidis GS,Maris TG,Nikiforaki K,Karantanas A,Marias K

    更新日期:2019-09-01 00:00:00

  • Determining the semantic similarities among Gene Ontology terms.

    abstract::We present in this paper novel techniques that determine the semantic relationships among GeneOntology (GO) terms. We implemented these techniques in a prototype system called GoSE, which resides between user application and GO database. Given a set S of GO terms, GoSE would return another set S' of GO terms, where ea...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/jbhi.2013.2248742

    authors: Taha K

    更新日期:2013-05-01 00:00:00

  • Enhancing Heart-Beat-Based Security for mHealth Applications.

    abstract::In heart-beat-based security, a security key is derived from the time difference between consecutive heart beats (the inter-pulse interval, IPI), which may, subsequently, be used to enable secure communication. While heart-beat-based security holds promise in mobile health (mHealth) applications, there currently exist...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2015.2496151

    authors: Seepers RM,Strydis C,Sourdis I,De Zeeuw CI

    更新日期:2017-01-01 00:00:00

  • An Attribute Supervised Probabilistic Dependent Matrix Tri-Factorization Model for the Prediction of Adverse Drug-Drug Interaction.

    abstract::Adverse drug-drug interaction (ADDI) becomes a significant threat to public health. Despite the detection of ADDIs is experimentally implemented in the early development phase of drug design, many potential ADDIs are still clinically explored by accidents, leading to a large number of morbidity and mortality. Several ...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2020.3048059

    authors: Zhu J,Liu Y,Zhang Y,Li D

    更新日期:2020-12-29 00:00:00

  • A Natural Language Processing Framework for Assessing Hospital Readmissions for Patients With COPD.

    abstract::With the passage of recent federal legislation, many medical institutions are now responsible for reaching target hospital readmission rates. Chronic diseases account for many hospital readmissions and chronic obstructive pulmonary disease has been recently added to the list of diseases for which the United States gov...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2017.2684121

    authors: Agarwal A,Baechle C,Behara R,Zhu X

    更新日期:2018-03-01 00:00:00

  • Nonnegative matrix factorization for the identification of EMG finger movements: evaluation using matrix analysis.

    abstract::Surface electromyography (sEMG) is widely used in evaluating the functional status of the hand to assist in hand gesture recognition, prosthetics and rehabilitation applications. The sEMG is a noninvasive, easy to record signal of superficial muscles from the skin surface. Considering the nonstationary characteristics...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2014.2326660

    authors: Naik GR,Nguyen HT

    更新日期:2015-03-01 00:00:00

  • MRI-based segmentation of pubic bone for evaluation of pelvic organ prolapse.

    abstract::Pelvic organ prolapse (POP) is a major women's health problem. Its diagnosis through magnetic resonance imaging (MRI) has become popular due to current inaccuracies of clinical examination. The diagnosis of POP on MRI consists of identifying reference points on pelvic bone structures for measurement and evaluation. Ho...

    journal_title:IEEE journal of biomedical and health informatics

    pub_type: 杂志文章

    doi:10.1109/JBHI.2014.2302437

    authors: Onal S,Lai-Yuen SK,Bao P,Weitzenfeld A,Hart S

    更新日期:2014-07-01 00:00:00