Abstract：
PURPOSE:To analyze the impact of tube potential and iodine concentration on the visibility of calcified plaques in coronary computed tomography angiography (cCTA). METHODS & MATERIALS:164 consecutive patients (65.9 % men and a mean age of 57.1 ± 11.3 years) with suspected coronary artery disease underwent calcium scoring (CaSc) scan followed by cCTA with topogram-based automated tube voltage selection (70 kV, 80 kV, 90 kV, 100 kV or 120 kV). In 127 Patients (HC), we injected 50 mL of contrast material (CM) with a concentration of 400 mg iodine per ml and in 37 patients (LC) 50 mL iodine concentration of 280 mg/mL. Sensitivity of cCTA for detecting calcified plaques was calculated with CaSc serving as gold standard. Density of CM enhanced coronary vessels and calcified plaques were quantified by region-of-interest (ROI) measurements in unenhanced and cCTA image series. RESULTS:Overall sensitivity of cCTA to detect calcified plaques was significantly higher using LC compared to HC (79 % vs. 73 %; p = 0.0035). The impact of LC was impressive at 70 kV with an improved sensitivity of 70 % vs. 57.1 % in HC (p = 0.0082). Furthermore, density values of HC enhanced coronary vessels exceeded those of calcified plaques, especially at low kV levels. In LC, except for the 70 kV setting, higher density values were shown for calculi than enhanced vessels. CONCLUSION:Low kV cCTA in routine using highly concentrated CM leads to reduced calcified plaque perceptibility and hence potentially underestimation of stenosis. Thus, low kV cCTA using CM with lower iodine concentration is necessary. In addition, a dose reduction up to 77.7 % can also be benefited.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Tischendorf P,Arendt CT,Scholtz JE,Leithner D,Vogl TJ,Bauer RW,Frellesen Cdoi
10.1016/j.ejrad.2020.109276subject
Has Abstractpub_date
2020-11-01 00:00:00pages
109276eissn
0720-048Xissn
1872-7727pii
S0720-048X(20)30465-4journal_volume
132pub_type
杂志文章abstract：:Positron emission tomography (PET) has proven to be a clinically valuable imaging modality, particularly for oncology staging and therapy follow-up. The introduction of combined PET/CT imaging has helped address challenging imaging situations when anatomical information on PET-only was inadequate for accurate lesion l...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2009.12.021
更新日期：2010-03-01 00:00:00
abstract：OBJECTIVE:Radiologists and other clinicians are facing an increasing number of illegal drug-related medical conditions. We aimed to draw attention to this growing global problem and to highlight some of the important points related to diagnosis and follow-up of body packing. We compare the diagnostic performance of une...
journal_title：European journal of radiology
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更新日期：2013-08-01 00:00:00
abstract：:The purpose of this study was to evaluate by CT the usefulness of the non-distension of the stomach in determining invasion of the gastric cancer into perigastric space and adjacent organs. Forty-eight patients with pathologically proved gastric cancer were studied by conventional CT. Patients were examined using two ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/s0720-048x(98)00024-2
更新日期：1998-11-01 00:00:00
abstract：PURPOSE:To report the diffusion-weighted MRI findings in alveolar echinococcosis (AE) of the liver and evaluate the potential role of apparent diffusion coefficients (ADCs) in the characterisation of lesions. MATERIALS AND METHODS:We retrospectively included 22 patients with 63 AE liver lesions (≥1 cm), examined with ...
journal_title：European journal of radiology
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abstract：:Dynamic CT in combination with intravenous bolus injection of contrast material provides a study of the pharmacokinetics in great vessels as well as in tissues. If the enhancement in the region of interest is plotted against time, the time-enhancement diagrams obtained reflect the contrast material passage mathematica...
journal_title：European journal of radiology
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doi：
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abstract：INTRODUCTION:Radiotherapy is increasingly used for both curative and palliative treatment of oesophageal malignancy. Accurate treatment depends on determining tumour location and length. This study assessed the value of PET-CT versus other staging modalities in determining tumour length. MATERIALS AND METHODS:Oesophag...
journal_title：European journal of radiology
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abstract：:The aim of this prospective study was to assess the accuracy of modern ultrasonography in diagnostic imaging of meniscal tears. One hundred and sixty menisci were evaluated in 80 patients (42 females, 38 males, mean age=36.2 years, range=16-70 years). Inclusion criteria for the study were twofold: clinical suspicion o...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2011.09.013
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journal_title：European journal of radiology
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更新日期：1986-05-01 00:00:00
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journal_title：European journal of radiology
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abstract：PURPOSE:To evaluate the pattern and risks for intrahepatic recurrence after percutaneous radiofrequency (RF) ablation for hepatocellular carcinoma (HCC). MATERIALS AND METHODS:We studied 62 patients with 72 HCCs (< or =4 cm) who were treated with percutaneous RF ablation. The mean follow-up period was 19.1 months (6.0...
journal_title：European journal of radiology
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更新日期：2014-02-01 00:00:00
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journal_title：European journal of radiology
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更新日期：2012-09-01 00:00:00
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journal_title：European journal of radiology
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doi：
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journal_title：European journal of radiology
pub_type： 杂志文章
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journal_title：European journal of radiology
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journal_title：European journal of radiology
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pub_type： 杂志文章,多中心研究
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journal_title：European journal of radiology
pub_type： 杂志文章
doi：
更新日期：1985-08-01 00:00:00
