Abstract:
:Agamococcidians are enigmatic and poorly studied parasites of marine invertebrates with unexplored diversity and unclear relationships to other sporozoans such as the human pathogens Plasmodium and Toxoplasma. It is believed that agamococcidians are not capable of sexual reproduction, which is essential for life cycle completion in all well studied parasitic apicomplexans. Here, we describe three new species of agamococcidians belonging to the genus Rhytidocystis. We examined their cell morphology and ultrastructure, resolved their phylogenetic position by using near-complete rRNA operon sequences, and searched for genes associated with meiosis and oocyst wall formation in two rhytidocystid transcriptomes. Phylogenetic analyses consistently recovered rhytidocystids as basal coccidiomorphs and away from the corallicolids, demonstrating that the order Agamococcidiorida Levine, 1979 is polyphyletic. Light and transmission electron microscopy revealed that the development of rhytidocystids begins inside the gut epithelial cells, a characteristic which links them specifically with other coccidiomorphs to the exclusion of gregarines and suggests that intracellular invasion evolved early in the coccidiomorphs. We propose a new superorder Eococcidia for early coccidiomorphs. Transcriptomic analysis demonstrated that both the meiotic machinery and oocyst wall proteins are preserved in rhytidocystids. The conservation of meiotic genes and ultrastructural similarity of rhytidocystid trophozoites to macrogamonts of true coccidians point to an undescribed, cryptic sexual process in the group.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Miroliubova TS,Simdyanov TG,Mikhailov KV,Aleoshin VV,Janouškovec J,Belova PA,Paskerova GGdoi
10.1038/s41598-020-72287-xsubject
Has Abstractpub_date
2020-09-28 00:00:00pages
15847issue
1issn
2045-2322pii
10.1038/s41598-020-72287-xjournal_volume
10pub_type
杂志文章abstract::Structured Progressive Circuit Class Therapy (SPCCT) was developed based on task-oriented therapy, providing benefits to patients' motivation and motor function. Training with Motor Imagery (MI) alone can improve gait performance in stroke survivors, but a greater effect may be observed when combined with SPCCT. Healt...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41598-020-63914-8
更新日期:2020-04-24 00:00:00
abstract::A new approach to estimate the Shannon entropy of a long-range correlated sequence is proposed. The entropy is written as the sum of two terms corresponding respectively to power-law (ordered) and exponentially (disordered) distributed blocks (clusters). The approach is illustrated on the 24 human chromosome sequences...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02721
更新日期:2013-01-01 00:00:00
abstract::Common features of immune-metabolic and inflammatory diseases such as metabolic syndrome, diabetes, obesity and cardiovascular diseases are an altered gut microbiota composition and a systemic pro-inflammatory state. We demonstrate that active immunization against the outer membrane protein of bacteria present in the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29353
更新日期:2016-07-07 00:00:00
abstract::Novel strategies to target Trypanosoma brucei, Trypanosoma cruzi and Leishmania are urgently needed to generate better and safer drugs against Human African Trypanosomiasis, Chagas disease and Leishmaniasis, respectively. Here, we investigated the feasibility of selectively targeting in trypanosomatids the ubiquitin E...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52618-3
更新日期:2019-11-07 00:00:00
abstract::The reproductive performance of Octopus vulgaris broodstocks fed two different diets (mixed fish [F group, BW 1,048.14 g] or mixed crustaceans [C group, BW 998.44 g]) was analyzed using an experimental recirculating aquaculture system consisting of a tank equipped with spawning and incubation chambers. A total of 8 fe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72151-y
更新日期:2020-09-17 00:00:00
abstract::Modelling the biokinetics of radionuclide excretion or retention is important in nuclear medicine and following accidental/malicious radioactivity releases. Sums of discrete exponential decay rates are often used, but we hypothesized that continuous probability distributions (CPD) of decay rates can describe the data ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38046-9
更新日期:2019-02-04 00:00:00
abstract::Visceral adiposity index (VAI) has been associated with various cardio-metabolic diseases; however, there is limited information about its association with cerebrovascular diseases. In this study, we evaluated the relationship between VAI and silent brain infarct (SBI). We evaluated a consecutive series of healthy vol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74454-6
更新日期:2020-10-14 00:00:00
abstract::By eliminating the spherical aberrations of microsphere we derived a simple but useful formula on the focusing of dielectric microsphere. On basis of this formula, not only can researchers determine the parameters of an optical microsphere system with super-resolution, but they can also perform parameter transformatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06146-7
更新日期:2017-07-18 00:00:00
abstract::The anti-diabetic biguanide drugs metformin (METF) and phenformin (PHEN) may have anti-cancer effects. Biguanides suppress plasma growth factors, but nonetheless, the view that these mitochondrial inhibitors accumulate in tumor tissue to an extent that leads to severe energetic stress or alleviation of hypoxia-induced...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10010-z
更新日期:2017-08-25 00:00:00
abstract::Soluble starch synthase I (SSI) is a key enzyme in the biosynthesis of plant amylopectin. In this study, the gene named IbSSI, was cloned from sweet potato, an important starch crop. A high expression level of IbSSI was detected in the leaves and storage roots of the sweet potato. Its overexpression significantly incr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02481-x
更新日期:2017-05-24 00:00:00
abstract::Quick inhibition of approach tendencies in response to signals of potential threats is thought to promote survival. However, little is known about the effect of viewing fearful expressions on the early dynamics of the human motor system. We used the high temporal resolution of single-pulse and paired-pulse transcrania...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14122
更新日期:2015-09-21 00:00:00
abstract::The aim of the current study is to assess whether total bile acid (TBA) level in first trimester pregnancy is associated with gestational diabetes mellitus (GDM). Biochemical parameters including serum TBA of 742 pregnant women were collected within 12 weeks of gestation and compared. At 24-28th weeks of gestation, 75...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34070
更新日期:2016-09-26 00:00:00
abstract::This paper reports the application of anthracite particles of different sizes and coated with nine kinds of layered double hydroxides (LDHs) varying in M(II)-M(III) cations, as alternative substrates in the simulated vertical-flow constructed wetland columns. Effects of LDHs-coating and particle size of modified anthr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15146
更新日期:2015-10-12 00:00:00
abstract::Two-dimensional (2D) acoustic vortex allows new physics and applications different from three-dimensional counterparts, yet existing mechanisms usually have to rely on active array composed of transducers which may result in complexity, high cost and, in particular, undesired spatial aliasing effect. We propose to gen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-60836-3
更新日期:2020-03-02 00:00:00
abstract::We propose efficient schemes of direct concurrence measurement for two-qubit spin and photon-polarization entangled states via the interaction between single-photon pulses and nitrogen-vacancy (NV) centers in diamond embedded in optical microcavities. For different entangled-state types, diversified quantum devices an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19482
更新日期:2016-01-18 00:00:00
abstract::We propose a method to simulate spin models in trapped ions using a digital-analog approach, consisting in a suitable gate decomposition in terms of analog blocks and digital steps. In this way, we show that the quantum dynamics of an enhanced variety of spin models could be implemented with substantially less number ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30534
更新日期:2016-07-29 00:00:00
abstract::Annually averaged solar radiation in the McMurdo Dry Valleys, Antarctica has varied by over 20 W m-2 during the past three decades; however, the drivers of this variability are unknown. Because small differences in radiation are important to water availability and ecosystem functioning in polar deserts, determining th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23390-7
更新日期:2018-03-22 00:00:00
abstract::A correction to this article has been published and is linked from the HTML version of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41598-017-18707-x
更新日期:2018-01-15 00:00:00
abstract::Mouse Tmc1 and Tmc2 are required for sensory transduction in cochlear and vestibular hair cells. Homozygous Tmc1∆/∆ mice are deaf, Tmc2∆/∆ mice have normal hearing, and double homozygous Tmc1∆/∆; Tmc2∆/∆ mice have deafness and profound vestibular dysfunction. These phenotypes are consistent with their different spatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29709-8
更新日期:2018-08-14 00:00:00
abstract::Artificially structured coatings are widely employed to minimize materials deterioration and corrosion, the annual direct cost of which is over 3% of the gross domestic product (GDP) for industrial countries. Manufacturing higher performance anticorrosive coatings is one of the most efficient approaches to reduce this...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01177
更新日期:2013-01-01 00:00:00
abstract::The present study investigated the treatment and survival outcomes of patients with synchronous primary esophageal squamous cell carcinoma and gastric adenocarcinoma. The medical records of 10,783 patients with primary esophageal squamous cancer treated at our institution between 1995 and 2012 were retrospectively rev...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13335
更新日期:2015-08-20 00:00:00
abstract::We study the tight-binding model for a graphene tube with perimeter N threaded by a magnetic field. We show exactly that this model has different nontrivial topological phases as the flux changes. The winding number, as an indicator of topological quantum phase transition (QPT) fixes at N/3 if N/3 equals to its intege...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31953
更新日期:2016-08-24 00:00:00
abstract::In summer 2010, a massive bloom appeared in the middle (16-25°N, 160-200°E) of the North Pacific Subtropical Gyre (NPSG) creating a spectacular oasis in the middle of the largest oceanic desert on Earth. Peaked in June 2010 covering over two million km2 in space, this phytoplankton bloom is the largest ever recorded b...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51989-x
更新日期:2019-10-29 00:00:00
abstract::Rapid facial mimicry (RFM) is an automatic response, in which individuals mimic others' expressions. RFM, only demonstrated in humans and apes, is grounded in the automatic perception-action coupling of sensorimotor information occurring in the mirror neuron system. In humans, RFM seems to reflect the capacity of indi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01527
更新日期:2013-01-01 00:00:00
abstract::Intelligent development is an inevitable choice for the green development of manufacturing enterprises, environmental regulations and green innovation play an important role in the intelligent development of manufacturing enterprises. By analyzing the interrelationships between environmental regulations, green innovat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71423-x
更新日期:2020-09-02 00:00:00
abstract::Inhibition of return (IOR), typically explored in cueing paradigms, is a performance cost associated with previously attended locations and has been suggested as a crucial attentional mechanism that biases orientation towards novelty. In their seminal IOR paper, Posner and Cohen (1984) showed that IOR is coded in spat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16586
更新日期:2015-11-13 00:00:00
abstract::Orientation controllable DNA biosensors hold great application potentials in recognizing small molecules and detecting DNA hybridization. Though electric field is usually used to control the orientation of DNA molecules, it is also of great importance and significance to seek for other triggered methods to control the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14415
更新日期:2015-09-24 00:00:00
abstract::1,3,5-trinitroperhydro-1,3,5-triazine (RDX), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX), and pentaerythritol tetranitrate (PETN), the major components in plastic explosives, pose a significant threat to public safety. A quick, sensitive, and low-cost detection method for these non-volatile explosives is ea...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25015
更新日期:2016-05-05 00:00:00
abstract::Critically endangered sturgeons, having undergone three whole genome duplication events, represent an exceptional example of ploidy plasticity in vertebrates. Three extant ploidy groups, combined with autopolyploidization, interspecific hybridization and the fertility of hybrids are important issues in sturgeon conser...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76680-4
更新日期:2020-11-12 00:00:00
abstract::The ability to respond appropriately to challenges is an important contributor to fitness. Variation in the regulation of glucocorticoid hormones, which mediate the phenotypic response to challenges, can therefore influence the ability to persist in a given environment. We compared stress responsiveness in four popula...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70161-4
更新日期:2020-08-13 00:00:00