Complex sociodemographic inequalities in consultations for low back pain: lessons from multilevel intersectional analysis.

abstract：:Long-term potentiation (LTP) in wide dynamic range (WDR) neurons in the dorsal horn has been suggested to contribute to central sensitization and the development of chronic pain. Indirect experimental evidence indicates an involvement of substance P (SP), in this respect. The aim of the present study was to monitor th...

journal_title：Pain

authors： Afrah AW,Fiskå A,Gjerstad J,Gustafsson H,Tjølsen A,Olgart L,Stiller CO,Hole K,Brodin E

更新日期：2002-03-01 00:00:00

abstract：:This study investigated the effects of a single administration of 6-(4-methoxyphenyl)-5-methyl-3-pyridinyl-4-isoxazolo[4,5-c]pyridin-4(5H)-one (MMPIP), a negative allosteric modulator (NAM) of metabotropic glutamate receptor 7 (mGluR7), on pain and on affective and cognitive behavior in neuropathic mice. The activity ...

journal_title：Pain

authors： Palazzo E,Romano R,Luongo L,Boccella S,De Gregorio D,Giordano ME,Rossi F,Marabese I,Scafuro MA,de Novellis V,Maione S

更新日期：2015-06-01 00:00:00

abstract：:Previous work has suggested an attenuated sensitivity to painful stimulation in hypertensive men. We recently reported that, compared with persons with negative parental history, men, but not women, with a positive history for hypertension showed attenuated pain perception. This study specifically addressed factors th...

journal_title：Pain

authors： al'Absi M,Petersen KL,Wittmers LE

更新日期：2000-10-01 00:00:00

abstract：:A cohort of 243 female sewing machine operators were studied by questionnaire and clinical examinations with the purpose to study the efficiency of a screening questionnaire-based method to identify prevalent and incident cases of neck-shoulder disorders. The cross-sectional correlation between self-reported neck-shou...

journal_title：Pain

authors： Kaergaard A,Andersen JH,Rasmussen K,Mikkelsen S

更新日期：2000-06-01 00:00:00

abstract：:A double-blind, 3-phase, cross-over, placebo-controlled trial of the pain-relieving effect of amitriptyline and carbamazepine was carried out in 15 patients with central post-stroke pain (CPSP) but without signs of depression. Treatment was given, in randomized order, for periods of 4 weeks, separated by 1 week wash-o...

journal_title：Pain

authors： Leijon G,Boivie J

更新日期：1989-01-01 00:00:00

abstract：:Peripheral nerve injury provokes heightened excitability of primary sensory afferents including nociceptors, and elicits ectopic activity in lesioned and neighboring intact nerve fibers. The major transmitter released by sensory afferents in the superficial dorsal horn of the spinal cord is glutamate. Glutamate is cri...

journal_title：Pain

authors： Inquimbert P,Bartels K,Babaniyi OB,Barrett LB,Tegeder I,Scholz J

更新日期：2012-12-01 00:00:00

abstract：:Pain is generally considered to have a sensory and an affective component. Clinical research has suggested that morphine more potently attenuates the affective component as compared to the sensory component. Because preclinical nociception models typically focus on the sensory component of nociception, and do not asse...

journal_title：Pain

authors： van der Kam EL,De Vry J,Schiene K,Tzschentke TM

更新日期：2008-06-01 00:00:00

abstract：:The effectiveness of a brief clinical and basic science seminar on pain for 1st year medical students was examined by comparing attitudes about pain prior to the seminar to attitudes 5 months after the seminar. The 6-h course combined written materials conveying facts about behavioral, social and biological aspects of...

journal_title：Pain

authors： Wilson JF,Brockopp GW,Kryst S,Steger H,Witt WO

更新日期：1992-09-01 00:00:00

abstract：:Extracellular nucleosides and nucleotides have widespread functions in responding to physiological stress. The "purinome" encompasses 4 G-protein-coupled receptors (GPCRs) for adenosine, 8 GPCRs activated by nucleotides, 7 adenosine 5'-triphosphate-gated P2X ion channels, as well as the associated enzymes and transpor...

journal_title：Pain

authors： Jacobson KA,Giancotti LA,Lauro F,Mufti F,Salvemini D

更新日期：2020-07-01 00:00:00

abstract：:Clinical trial participants often require additional instruction to prevent idiosyncratic interpretations regarding completion of patient-reported outcomes. The Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) public-private partnership developed a tr...

journal_title：Pain

authors： Smith SM,Amtmann D,Askew RL,Gewandter JS,Hunsinger M,Jensen MP,McDermott MP,Patel KV,Williams M,Bacci ED,Burke LB,Chambers CT,Cooper SA,Cowan P,Desjardins P,Etropolski M,Farrar JT,Gilron I,Huang IZ,Katz M,Kerns RD

更新日期：2016-05-01 00:00:00

abstract：:Endogenous pain inhibition is less efficient in chronic pain patients. Diffuse noxious inhibitory control (DNIC), a form of endogenous pain inhibition, is compromised in women and older people, making them more vulnerable to chronic pain. However, the underlying mechanisms remain unclear. Here, we used a capsaicin-ind...

journal_title：Pain

authors： Da Silva JT,Tricou C,Zhang Y,Seminowicz DA,Ro JY

更新日期：2020-06-01 00:00:00

abstract：:The present paper describes the effect of vibratory stimulation on pain of dental origin in 36 patients. The patients were from a clinic for dental surgery and all had suffered pain from pulpal inflammation, apical periodontitis or postoperative pain following extraction of an impacted wisdom tooth for more than 2 day...

journal_title：Pain

authors： Ottoson D,Ekblom A,Hansson P

更新日期：1981-02-01 00:00:00

abstract：:The purpose of this study was to develop and validate a measure of patient satisfaction for patients receiving treatment for either acute or chronic pain: the Pain Treatment Satisfaction Scale (PTSS). Development of the initial questionnaire included a comprehensive literature review and interviews with patients, phys...

journal_title：Pain

authors： Evans CJ,Trudeau E,Mertzanis P,Marquis P,Peña BM,Wong J,Mayne T

更新日期：2004-12-01 00:00:00

abstract：:Fibromyalgia (FM) is a common and often debilitating chronic pain condition. Research shows that symptoms of depression and anxiety are present in up to three quarters of individuals with FM. Of concern, most adults with FM cannot access traditional face-to-face cognitive behavioural pain management programs, which ar...

journal_title：Pain

authors： Friesen LN,Hadjistavropoulos HD,Schneider LH,Alberts NM,Titov N,Dear BF

更新日期：2017-04-01 00:00:00

abstract：:We previously reported that morphine fails to produce analgesic tolerance when administered in the presence of formalin-induced pain. The hypothalamic-pituitary-adrenal (HPA) axis is known to respond to stressful stimuli, including pain. To examine whether the blockade of tolerance by pain is related to HPA activity, ...

journal_title：Pain

authors： Vaccarino AL,Couret LC Jr

更新日期：1995-12-01 00:00:00

abstract：:Coping with the demands of pain diminishes self-regulatory capacity and causes self-regulatory fatigue, which then leads to deteriorated executive task performance. It has been suggested that optimism can counteract the depletion of self-regulatory capacity. This study employed a 2 (optimism/no optimism)×2 (pain/no pa...

journal_title：Pain

authors： Boselie JJLM,Vancleef LMG,Smeets T,Peters ML

更新日期：2014-02-01 00:00:00

abstract：:The left dorsolateral prefrontal cortex (DLPFC) is involved in the experience and modulation of pain, and may be an important node linking pain and cognition. Repetitive transcranial magnetic stimulation (rTMS) to the left DLPFC can reduce chronic and experimental pain. However, whether left DLPFC rTMS can influence t...

journal_title：Pain

authors： Seminowicz DA,de Martino E,Schabrun SM,Graven-Nielsen T

更新日期：2018-12-01 00:00:00

abstract：:In knee osteoarthritis (OA), pain sensitization has been linked to a more severe symptomatology, but the prognostic implications of pain sensitivity in people undergoing conservative treatment such as physiotherapy are not established. This study aimed to prospectively investigate the association between features of p...

journal_title：Pain

authors： OʼLeary H,Smart KM,Moloney NA,Blake C,Doody CM

更新日期：2018-09-01 00:00:00

abstract：:The aims of this study were two-fold: first, to simplify the method for creating a recently described neuropathic pain model in the rat, and second, to evaluate the effects of a number of drugs with analgesic or antihyperalgesic properties, in this model. Continuous intravenous vincristine infusion (1-100 microg kg(-1...

journal_title：Pain

authors： Nozaki-Taguchi N,Chaplan SR,Higuera ES,Ajakwe RC,Yaksh TL

更新日期：2001-07-01 00:00:00

abstract：:In humans, chronic psychological stress is associated with increased intestinal paracellular permeability and visceral hyperalgesia, which is recapitulated in the chronic intermittent water avoidance stress (WAS) rat model. However, it is unknown whether enhanced visceral pain and permeability are intrinsically linked...

journal_title：Pain

authors： Creekmore AL,Hong S,Zhu S,Xue J,Wiley JW

更新日期：2018-09-01 00:00:00

abstract：:Visceral inflammation is thought to play an important role in the sensitization of low and high threshold mechanosensory and polymodal afferents and to recruit silent nociceptors. Yet, little is known about the potential role of the mediators involved in nociceptor sensitization to mechanical stimulation as compared t...

journal_title：Pain

authors： Roza C,Reeh PW

更新日期：2001-09-01 00:00:00

abstract：:Pain catastrophizing is a significant risk factor for patients with knee osteoarthritis (KOA) and thus is a target for many psychological interventions for pain. This study examined if interventions targeting sleep found to be effective in improving sleep in KOA also reduce pain catastrophizing measured as a trait thr...

journal_title：Pain

authors： Lerman SF,Finan PH,Smith MT,Haythornthwaite JA

更新日期：2017-11-01 00:00:00

abstract：:Postmastectomy pain (PMP), a distinctive postsurgical neuropathic pain syndrome, has been thought to be consequence of 4-6% of surgical procedures for cancer of the breast, but remains understudied and poorly documented. In this cross-sectional descriptive study, a convenience sample of 95 women who had undergone brea...

journal_title：Pain

authors： Stevens PE,Dibble SL,Miaskowski C

更新日期：1995-04-01 00:00:00

abstract：:The present study utilized recently developed diagnostic tests that permit recognition of functional deficits in spine mobility, trunk strength, endurance, coordination, and dynamic lifting capacity. Changes in these tests were compared to changes in psychological functioning (e.g., self-report of pain) as well as to ...

journal_title：Pain

authors： Mayer TG,Gatchel RJ,Kishino N,Keeley J,Mayer H,Capra P,Mooney V

更新日期：1986-04-01 00:00:00

abstract：:Fear-avoidance beliefs have been identified as an important psychosocial variable in patients with chronic disability doe to low back pain. The importance of fear-avoidance beliefs for individuals with acute low back pain has not been explored. Seventy-eight subjects with work-related low back pain of less than 3 week...

journal_title：Pain

authors： Fritz JM,George SZ,Delitto A

更新日期：2001-10-01 00:00:00

abstract：:Fourteen patients whose post-herpetic neuralgia could not be alleviated by conventional methods were treated with cryocautery using a stick of solid carbon dioxide (dry ice) applied directly to the hyperesthetic skin areas of the cutaneous scars. Follow-up evaluation revealed that 5 of 14 subjects maintained excellent...

journal_title：Pain

authors： Suzuki H,Ogawa S,Nakagawa H,Kanayama T,Taj K,Saitoh H,Ohshima Y

更新日期：1980-12-01 00:00:00

abstract：:The effects of nitrous oxide (N2O) are thought to be mediated by several pharmacological pathways at different levels of the central nervous system. Here, we focus on excitatory glutamatergic transmission in the superficial dorsal horn of the spinal cord with respect to its importance for the nociceptive processing. T...

journal_title：Pain

authors： Georgiev SK,Kohno T,Ikoma M,Yamakura T,Baba H

更新日期：2008-01-01 00:00:00

abstract：:TRPV1 is expressed in a subpopulation of myelinated Aδ and unmyelinated C-fibers. TRPV1+ fibers are essential for the transmission of nociceptive thermal stimuli and for the establishment and maintenance of inflammatory hyperalgesia. We have previously shown that high-power, short-duration pulses from an infrared diod...

journal_title：Pain

authors： Mitchell K,Lebovitz EE,Keller JM,Mannes AJ,Nemenov MI,Iadarola MJ

更新日期：2014-04-01 00:00:00

abstract：:Existing estimates of sociodemographic disparities in chronic pain in the United States are based on cross-sectional data, often treat pain as a binary construct, and rarely test for nonresponse or other types of bias. This study uses 7 biennial waves of national data from the Health and Retirement Study (1998-2010; n...

journal_title：Pain

authors： Grol-Prokopczyk H

更新日期：2017-02-01 00:00:00

abstract：:Tactile, proprioceptive, and nociceptive information, including also chemosensory functions are expressed in the trigeminal nerve sensory response. To study differences in the processing of different stimulus qualities, we performed a study based on functional magnetic resonance imaging. The first trigeminal branch (o...

journal_title：Pain

authors： Iannilli E,Del Gratta C,Gerber JC,Romani GL,Hummel T

更新日期：2008-10-15 00:00:00