Abstract:
:We wanted to explore possible differences in disease presentation, frequency, and age of onset of dementia with Lewy bodies (DLB) between first-generation immigrants (FGI) and patients born in Belgium (PBIB). We conducted a retrospective study on all patients of our Memory Clinic between June 1, 2010 and January 31, 2020. A synucleinopathy was diagnosed in 150 of 2702 patients (5.5%): 91 received a diagnosis of DLB (3.4%). FGI were two times more likely to receive a diagnosis of DLB, due to a higher prevalence in North-Africans and Latin-Americans. Visual hallucinations were less frequent in North-Africans than in other immigrants. FGI were younger than PBIB and reported more often parasomnia. Our data suggest a higher risk for DLB in certain immigrant groups. Especially for North-African patients, a genetic factor can be suspected, namely mutations in Leucine-rich repeat kinase 2 (LRRK2). Memory clinics with a high rate of FGI may provide interesting data and insights into the prevalence of DLB, genetic and environmental differences.
journal_name
Acta Neurol Belgjournal_title
Acta neurologica Belgicaauthors
Segers K,Benoit F,Meyts JM,Glibert G,Levy S,Surquin Mdoi
10.1007/s13760-020-01492-2subject
Has Abstractpub_date
2020-09-15 00:00:00eissn
0300-9009issn
2240-2993pii
10.1007/s13760-020-01492-2pub_type
杂志文章abstract::Rheumatoid arthritis (RA) is a chronic disease, the etiology of which has yet to be clarified, which causes activation of proinflammatory pathways that bring about joint and systemic inflammation. Although peripheral nervous system anomalies are observed widely in RA, very few case reports on changes in the central ne...
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abstract::The aim of this study was to compare the incidence of postoperative, surgery-related complications in patients where fluorescein video angiography (FL-VA) was performed with those operated without intraoperative verification. This is an observational cohort study including 97 patients who were selected for microsurgic...
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journal_title:Acta neurologica Belgica
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pub_type: 杂志文章,评审
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journal_title:Acta neurologica Belgica
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pub_type: 杂志文章
doi:10.1007/s13760-018-0954-4
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:10.1007/s13760-019-01137-z
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章
doi:
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journal_title:Acta neurologica Belgica
pub_type: 杂志文章,评审
doi:
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pub_type: 杂志文章
doi:
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pub_type: 杂志文章
doi:
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journal_title:Acta neurologica Belgica
pub_type: 信件
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