Abstract:
PURPOSE:The rapidly growing and emerging nature of biologics have made indications for regenerative and reparative hip therapies ever changing, with at times only early-stage evidence for their use. The purpose of this study was to review and summarize the currently available data on the management of hip cartilage injuries and osteoarthritis. METHODS:A scoping review of the available scientific literature for hip biologics was performed, with available evidence for hyaluronic acid (HA), platelet rich plasma (PRP), stem/stromal cells, microfracture, mosaicplasty, osteochondral allograft, and cell-based therapies investigated. RESULTS:To date, there exist better guidelines and further consensus concerning knee joint biologic treatments than the hip due to a greater number of studies as well as the more recent emergence of hip preservation approaches. However, increasing evidence is available for the selective implementation of biologics on an individualized basis with attention to lesion size and location. CONCLUSION:Orthopedic surgeons are at an exciting crossroads in medicine, where hip biologic therapies are evolving and increasingly available. Timetested interventions such as arthroplasty have shown good results and still have a major role to play but newer, regenerative approaches have the potential to effectively delay or reduce the requirement for such invasive procedures.
journal_name
Int Orthopjournal_title
International orthopaedicsauthors
Hevesi M,Jacob G,Shimomura K,Ando W,Nakamura N,Krych AJdoi
10.1007/s00264-020-04789-2subject
Has Abstractpub_date
2021-02-01 00:00:00pages
319-333issue
2eissn
0341-2695issn
1432-5195pii
10.1007/s00264-020-04789-2journal_volume
45pub_type
杂志文章abstract::Deep-vein thrombosis (DVT) and pulmonary embolism (PE) represent life-threatening postoperative complications frequently responsible for in-hospital mortality following total knee arthroplasty (TKA). Mechanical prophylaxis in the form of a foot pump offers an alternative to pharmacological and physical therapy. The ai...
journal_title:International orthopaedics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00264-010-1091-8
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:Aged patients represent a high risk group for acquiring spinal tuberculosis, and it still remains a leading cause of kyphosis and paraplegia in developing nations. Aged patients often combined with cardiovascular and respiratory disease and single lung ventilation via anterior approach surgery could result in m...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-016-3161-z
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Despite previous studies the management of Rockwood type III acromioclavicular (AC) dislocations remains controversial and the debate continues about whether patients with Rockwood type III AC injuries should be treated conservatively or operatively. In this study, we will review the current literature and pres...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-013-2143-7
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine the location of the anterior humeral circumflex artery and axillary nerve based on bony landmarks, and to provide anatomical information that enables a safe approach when treating a proximal humeral fractures. METHODS:Thirty cadavers were included. The distances of bo...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-011-1394-4
更新日期:2012-04-01 00:00:00
abstract:INTRODUCTION:Literature on the potential release of trace elements following implantation of Zirconia-platelet toughened alumina (ZPTA) ceramic components is scant. The present study therefore analysed the in vitro and in vivo potential release of ions from ZPTA bearings. MATERIAL AND METHODS:An in vitro and in vivo s...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-017-3568-1
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:Sciatic nerve palsy after periacetabular osteotomy (PAO) is a serious complication. The purpose of this study was to determine whether a multimodal sciatic monitoring technique allows for identification of surgical steps that place the sciatic nerve at risk. METHODS:Transcranial electrical motor evoked potenti...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-016-3394-x
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:Stage II posterior tibial tendon dysfunction (PTTD) can be treated by flexor digitorum longus (FDL) tendon transfer and medial displacement calcaneal osteotomy (MDCO). Numerous authors have studied the clinical and radiographic results of this procedure. However, little is known about the kinematic changes. The...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-013-2071-6
更新日期:2013-09-01 00:00:00
abstract::We describe a method of quantifying the lateral/medial thrust of the knee which occurs in the early phase of walking. We have used this method to evaluate the effects of wedged insoles on the lateral and medial thrust for normal knees and knees with unicompartment osteoarthritis (OA). A laterally elevated (valgus) ins...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640050174
更新日期:1997-01-01 00:00:00
abstract::We carried out a retrospective review of 32 consecutive patients (30 adults and two children) with total or partial lesions of the brachial plexus who had surgical repair using nerve grafting, neurotisation, and neurolysis between January 1991 and December 2003. The outcome measures of muscular strength were correlate...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-005-0017-3
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:Indications for amputation in natural disasters are not the same compared to our daily practice. They must be determined by those with great surgical experience and good knowledge of military or disaster surgical doctrine. Unfortunately, nowadays few surgeons have this experience. In fact, some volunteer surgeo...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1548-z
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:Aseptic loosening is a serious complication after total joint arthroplasty. Plain radiography, along with clinical signs of prosthesis loosening, is the technique of first choice to evaluate loosening of joint replacements. Nevertheless, radiographical signs of osteolysis may not be apparent until progressed st...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-014-2471-2
更新日期:2014-12-01 00:00:00
abstract::The purpose of this study was to evaluate concentrated autologous bone marrow aspirate transplantation (CABMAT) treatment for corticosteroid-induced osteonecrosis of the femoral head (ONFH) in systemic lupus erythematosus (SLE). Bone marrow was aspirated from iliac crests, concentrated on a conventional manual blood b...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-010-1048-y
更新日期:2011-06-01 00:00:00
abstract::Cementless acetabular components require good initial fixation to allow bony in-growth. The initial press-fit stability, important for designs that do not rely on supplemental fixation, was examined for three designs with different porous coating systems: beads, fiber mesh, and plasma spray. The ability to withstand t...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-001-0314-4
更新日期:2002-01-01 00:00:00
abstract::Twenty three patients with lumbar spondylolisthesis (6 Grade I, 14 Grade II and 3 Grade III) with low back pain, and radicular pain in 14, were treated surgically when they failed to respond to conservative treatment. Their average age was 33.2 years. Bilateral posterolateral spinal fusions with autologous iliac bone ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640050249
更新日期:1998-01-01 00:00:00
abstract::Reverse total shoulder arthroplasty (RTSA) has been reported to be associated with a complication rate that is four times that of conventional total shoulder arthroplasty. It is the purpose of this article to identify and understand the most common and most serious complications of RTSA and to review current methods o...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-010-1125-2
更新日期:2010-12-01 00:00:00
abstract::A case of bilateral habitual dislocation of the patella associated with cleft lip and palate, and short metatarsals, metacarpals and phalanges is reported. The possible cause of habitual dislocation is discussed in the light of 20 cases which have been seen by the author. ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00183358
更新日期:1990-01-01 00:00:00
abstract::The contamination of drinking water by organic acids, selenium deficiency and the ingestion of fungal mycotoxins are the three main aetiological factors in the development of Kashin-Beck disease. An avian tibial chondrodysplasia induced by mycotoxins has been reported. Deoxynivalenol (DON) is one of many mycotoxins pr...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640100235
更新日期:2001-01-01 00:00:00
abstract::The authors report seven cases of desmoid tumors of the extremities. A tumour less than a few centimetres in size is best removed by wide local excision. Large growths should also be excised, but efforts should be made to preserve the vessels and nerves, since malignant transformation and metastases do not occur. Irra...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00547171
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:Humero-ulnar external fixation has been proposed to treat complex supracondylar humeral fractures in children. It facilitates fracture reduction and reduces the risk of ulnar nerve lesion, which can occur after cross pinning. METHODS:In a ten year period, 28 children have been operated on in our centre by hume...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-016-3251-y
更新日期:2016-11-01 00:00:00
abstract::A retrospective study evaluating complications in 2,233 consecutive patients of subaxial cervical disorders treated with an anterior cervical locking plate was performed, and recommendations for prevention and treatment were made. The average length of follow-up was 1.3 years. Any loosening or breaking of the plates a...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-007-0369-y
更新日期:2008-10-01 00:00:00
abstract::A series of 49 pilon fractures in a tertiary referral centre treated definitively by open reduction and internal fixation have been assessed and the complications of such injuries examined. A retrospective analysis of case notes, radiographs and computerised tomographs over a seven-year period from 1999-2006 was perfo...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-010-1005-9
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:Peri-radicular injection is a widely used procedure for treating lumbar radicular pain, but it remains unclear what types of lumbar pathologies respond well to this treatment. We aimed to investigate the efficacy of peri-radicular injection for degenerative lumbar disorders and to determine what types of pathol...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-015-2761-3
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:The review aims to provide a summary of the current literature regarding common medications prescribed in orthopaedic surgery and their potential implications in COVID-19 patients. METHODS:A systematic review was performed using the PRISMA guidelines. All clinical studies, reviews, consensus and guidelines rel...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-020-04643-5
更新日期:2020-08-01 00:00:00
abstract::We have assessed the oncological and functional results of limb salvage surgery using a custom-made endoprosthetic replacement in six patients (mean age 17 years) with distal tibial osteosarcoma (stage IIB). A wide margin excision was possible in three, marginal in two and contaminated in one. Skeletal reconstruction ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640000172
更新日期:2000-01-01 00:00:00
abstract::Over 10 years, 842 consecutive autopsies on patients dying from a malignant neoplasm were evaluated microscopically to determine the incidence of spinal and skeletal metastases. Vertebral wedging, sclerosis and areas of osteolysis were defined as features of spinal metastases. The incidence was 30.6%, 65% of which aro...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00181116
更新日期:1995-01-01 00:00:00
abstract::An osteosarcoma developed in a boy, 16 years of age, 9 years after staples had been inserted in the region of the lower femoral epiphysis. The possible association between the implant and the tumour is discussed. ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640050090
更新日期:1996-01-01 00:00:00
abstract::Following amputation of a limb for osteosarcoma, the tumour was serially transferred to nude mice. The rate of growth was determined and the inhibitory effect of Cyclophosphamide, Adriamycin and 5-Fluorouracil was assessed in three separate experimental animal groups. In the tumour studied. Cyclophosphamide produced t...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00267728
更新日期:1982-01-01 00:00:00
abstract::The haematological and orthopaedic complications of patients with sickle cell disease from two different regions of Arabia are presented. Nineteen patients from the South-western region were matched for age and sex with an equal number from the Eastern region. The mean sickle cell haemoglobin was 75.95% in those from ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00182718
更新日期:1992-01-01 00:00:00
abstract::We give details of seven children with the TAR syndrome, Thrombocytopenia with absence of the radius. Two of the children were siblings. The TAR syndrome is characterised by hypomegakaryocytic thrombocytopenia and bilateral absence of the radius. It is inherited as an autosomal recessive trait. ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00179704
更新日期:1991-01-01 00:00:00
abstract::Osteofibrous dysplasia of the tibia in children will commonly recur after surgical resection. The use of a leg brace until puberty offers a useful method of conservative management. Seven female patients, age three months to nine years at the time of brace treatment, have been followed for 3.5 to 18 years, an average ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00180213
更新日期:1992-01-01 00:00:00