Abstract：
:Shoot formation is accompanied by active cell proliferation and expansion, requiring that metabolic state adapts to developmental control. Despite the importance of such metabolic reprogramming, it remains unclear how development and metabolism are integrated. Here, we show that disruption of ANGUSTIFOLIA3 orthologs (PpAN3s) compromises gametophore shoot formation in the moss Physcomitrium patens due to defective cell proliferation and expansion. Trans-omics analysis reveals that the downstream activity of PpAN3 is linked to arginine metabolism. Elevating arginine level by chemical treatment leads to stunted gametophores and causes Ppan3 mutant-like transcriptional changes in the wild-type plant. Furthermore, ectopic expression of AtAN3 from Arabidopsis thaliana ameliorates the defective arginine metabolism and promotes gametophore formation in Ppan3 mutants. Together, these findings indicate that arginine metabolism is a key pathway associated with gametophore formation and provide evolutionary insights into the establishment of the shoot system in land plants through the integration of developmental and metabolic processes.
journal_name
Cell Repjournal_title
Cell reportsauthors
Kawade K,Horiguchi G,Hirose Y,Oikawa A,Hirai MY,Saito K,Fujita T,Tsukaya Hdoi
10.1016/j.celrep.2020.108127subject
Has Abstractpub_date
2020-09-08 00:00:00pages
108127issue
10issn
2211-1247pii
S2211-1247(20)31116-5journal_volume
32pub_type
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