Abstract：
:In addition to its role in movement, human skeletal muscle also plays important roles in physiological activities related to metabolism and the endocrine system. Aging and disease onset and progression can induce the reduction of skeletal muscle mass and function, thereby exacerbating skeletal muscle atrophy. Recent studies have confirmed that skeletal muscle atrophy is mainly controlled by the balance between protein synthesis and degradation, the activation of satellite cells, and mitochondrial quality in skeletal muscle. Circadian rhythm is an internal rhythm related to an organism's adaptation to light-dark or day-night cycles of the planet, and consists of a core biological clock and a peripheral biological clock. Skeletal muscle, as the most abundant tissue in the human body, is an essential part of the peripheral biological clock in humans. Increasing evidence has confirmed that maintaining a normal circadian rhythm can be beneficial for increasing protein content, improving mitochondrial quality, and stimulating regeneration and repairing of cells in skeletal muscle to prevent or alleviate skeletal muscle atrophy. In this review, we summarize the roles and underlying mechanisms of circadian rhythm in delaying skeletal muscle atrophy, which will provide a theoretical reference for incorporating aspects of circadian rhythm to the prevention and treatment of skeletal muscle atrophy.
journal_name
Ageing Res Revjournal_title
Ageing research reviewsauthors
Zhang H,Liang J,Chen Ndoi
10.1016/j.arr.2020.101155subject
Has Abstractpub_date
2020-11-01 00:00:00pages
101155eissn
1568-1637issn
1872-9649pii
S1568-1637(20)30290-7journal_volume
63pub_type
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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更新日期：2002-06-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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更新日期：2019-11-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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更新日期：2002-02-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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更新日期：2014-11-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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更新日期：2014-05-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2016.06.006
更新日期：2016-11-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2006.03.007
更新日期：2006-05-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2014.12.008
更新日期：2015-09-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2020.101211
更新日期：2021-01-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2020.101201
更新日期：2020-12-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2020.101156
更新日期：2020-12-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2004.05.002
更新日期：2004-11-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2009.03.001
更新日期：2009-07-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2009.07.001
更新日期：2010-04-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2018.04.001
更新日期：2018-07-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2019.03.001
更新日期：2019-05-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2020.101089
更新日期：2020-08-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2012.01.003
更新日期：2012-09-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
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更新日期：2020-08-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2019.100966
更新日期：2019-12-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2011.12.004
更新日期：2012-04-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2019.04.001
更新日期：2019-07-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2018.08.004
更新日期：2018-11-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2015.03.004
更新日期：2015-09-01 00:00:00
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journal_title：Ageing research reviews
pub_type： 杂志文章,评审
doi：10.1016/j.arr.2021.101258
更新日期：2021-01-12 00:00:00
