Application of optimized digital surgical guides in mandibular resection and reconstruction with vascularized fibula flaps: Two case reports.


RATIONALE:Currently, digital surgical techniques have been widely used in the precise treatment of mandibular resection and reconstruction with fibula flaps. Utilizing these innovative techniques in surgical planning and hardware fabrication before surgery has shown to provide great help. However, it is difficult for even experienced surgeons to place the preformed reconstruction plate in the same position as its preoperative design, causing surgical results to differ from preoperative planning. This study aims to solve these acknowledged challenges by creating newly designed equipment. PATIENT CONCERNS:Two patients suffering from long-term expansion of the mandible were admitted to our department. Case I was a 39-year-old female patient who was concerned about the disease in the middle of the mandible, Case II was a 45-year-old female patient who was concerned about the disease at the left mandibular angle and ramus region. DIAGNOSES:Two patients were diagnosed with the mandibular ameloblastoma based on computed tomography (CT) scan and pathological results. INTERVENTIONS:Personalized 3-dimensional (3D) surgical guides were applied to 2 patients with mandibular ameloblastoma who underwent mandibular resection and reconstruction with vascularized fibula flaps using a specially optimized and designed reconstruction guide plate. OUTCOMES:We achieved precise mandibular repair with such a guide in full accordance with the preoperative plan and ensured the restoration of patient facial symmetry. LESSONS:Optimized reconstruction guide template could accurately locate the preformed reconstruction plate. This component had the ability to ensure that the location of the actual reconstruction plates were highly consistent with preoperative designed models.


Medicine (Baltimore)




Han L,Zhang X,Guo Z,Long J




Has Abstract


2020-08-28 00:00:00
















  • Laparoscopic approach to an incidentally found pelvic retroperitoneal liposarcoma: Case report and review.

    abstract:RATIONALE:Well-differentiated liposarcomas (WDLPS) are rare retroperitoneal tumors that can reach significant size as they can grow without constrains before becoming symptomatic. Laparotomic open radical tumor resection represents the most common surgical approach. PATIENT CONCERNS:A mass with "fat fluid level" was f...


    pub_type: 杂志文章


    authors: Mandato VD,Mastrofilippo V,De Marco L,Aguzzoli L

    更新日期:2019-04-01 00:00:00

  • Dab2 gene variant is associated with increased coronary artery disease risk in Chinese Han population.

    abstract::Disabled-2 (Dab2) is a clathrin and cargo-binding endocytic adaptor protein that plays a role in cellular trafficking of low-density lipoprotein receptor (LDLR). However, little is known about its involvement in coronary artery disease (CAD). Here, we aimed to investigate the association between Dab2 single-nucleotide...


    pub_type: 杂志文章


    authors: Wang Y,Wang Y,Adi D,He X,Liu F,Abudesimu A,Fu Z,Ma Y

    更新日期:2020-07-02 00:00:00

  • Liver stiffness measurement and spleen diameter as predictors for the presence of esophageal varices in chronic hepatitis C patients.

    abstract::Although it is an invasive and unpleasant procedure, esophagogastroduodenoscopy (EGD) is still the gold standard for esophageal varices (EV) detection. The aim of this study was to investigate liver stiffness measurement (LSM) and spleen diameter as simple noninvasive tools for EV prediction in chronic hepatitis C pat...


    pub_type: 杂志文章


    authors: Tag-Adeen M,Alsenbesy M,Ghweil AA,Abd Elrazek MAH,Elgohary EA,Sallam MM,Ismael A,Nawara A

    更新日期:2017-11-01 00:00:00

  • Antenatal infection and intraventricular hemorrhage in preterm infants: A meta-analysis.

    abstract:BACKGROUND:The aim of this study was to summarize current evidence evaluating the association between antenatal infection and intraventricular hemorrhage (IVH) in preterm infants. MATERIALS AND METHODS:We searched for published articles on antenatal infection and IVH in 3 English (PubMed, the Cochrane Library, and EBS...


    pub_type: 杂志文章,meta分析


    authors: Huang J,Meng J,Choonara I,Xiong T,Wang Y,Wang H,Qu Y,Mu D

    更新日期:2019-08-01 00:00:00

  • Diagnosis of hereditary diffuse leukoencephalopathy with neuroaxonal spheroids based on next-generation sequencing in a family: Case report and literature review.

    abstract:RATIONALE:Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) is a rare disease with white matter lesions of the central nervous system, and it usually has autosomal dominant inheritance. Its pathogenesis and causes are complex, and it has obvious clinical and genetic heterogeneities; also, it is c...


    pub_type: 杂志文章,评审


    authors: Shi T,Li J,Tan C,Chen J

    更新日期:2019-05-01 00:00:00

  • Multiple Primary Malignancies in Patients With Hepatocellular Carcinoma: A Largest Series With 26-Year Follow-Up.

    abstract::Multiple primary malignancies (MPMs) are defined as 2 or more malignancies without subordinate relationship detected in different organs of an individual patient. Reports addressing MPM patients with hepatocellular carcinoma (HCC) are rare. We perform a 26-year follow-up study to investigate characteristics and progno...


    pub_type: 杂志文章


    authors: Xu W,Liao W,Ge P,Ren J,Xu H,Yang H,Sang X,Lu X,Mao Y

    更新日期:2016-04-01 00:00:00

  • Effect of digital storytelling intervention on burnout thoughts of adolescent: Athletes with disabilities.

    abstract:BACKGROUND/OBJECTIVE:Both athletes with and without disabilities can develop burnout symptoms. However, athletes with disabilities may face different or more challenges compared to their counterparts without disabilities. The present study aimed at ascertaining the effect of digital storytelling intervention on burnout...


    pub_type: 杂志文章,随机对照试验


    authors: Ofoegbu TO,Asogwa UD,Ogbonna CS,Aloh HE,Eseadi C,Eskay M,Nji GC,Ngwoke OR,Agboti CI,Nnachi RA,Nnachi OC,Otu MS

    更新日期:2020-07-24 00:00:00

  • Use of RENAL nephrometry scores for predicting tumor upgrading between core biopsies and surgical specimens: a prospective ex vivo study.

    abstract::Determination of Fuhrman grade (FG) on biopsies of renal masses is relatively inaccurate, being prone to underestimating the true grade as ascertained from surgical specimens. This study evaluated whether anatomical features of tumors could predict tumor upgrading between core biopsies and surgical specimens. We prosp...


    pub_type: 临床试验,杂志文章


    authors: Zhang GM,Zhu Y,Gan HL,Wang HK,Shi GH,Zhang HL,Dai B,Wang CF,Ye DW

    更新日期:2015-02-01 00:00:00

  • Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome in Adults: Prognostic Factors for Outcomes.

    abstract::Despite a therapeutic option for severe acute respiratory distress syndrome (ARDS), the survival benefit of venovenous extracorporeal membrane oxygenation (VV-ECMO) is still controversial in adults. This study was aimed at investigating the prognostic factors for ECMO-treated ARDS in adult patients.From 2012 to 2015, ...


    pub_type: 杂志文章


    authors: Wu MY,Huang CC,Wu TI,Wang CL,Lin PJ

    更新日期:2016-02-01 00:00:00

  • A special superior cortex compressive fracture of femoral neck: Two case reports.

    abstract:RATIONALE:Garden type I femoral neck fractures are incomplete stable fractures with impaction in valgus fractures that the question of whether there exists Garden type I femoral neck fracture is currently uncertain. There is still disagreement on the existence of the Garden type I fractures. PATIENT CONCERNS:Herein we...


    pub_type: 杂志文章


    authors: Xian H,Zhang H,Lian K,Lin D

    更新日期:2018-10-01 00:00:00

  • Influence of blood pressure variability on early carotid atherosclerosis in hypertension with and without diabetes.

    abstract::Carotid intima-media thickness (IMT) has been one widely used index of early carotid atherosclerosis. We speculated that the influence of blood pressure variability (BPV) on early carotid atherosclerosis may be varied by the location of the carotid artery and diabetes history. Thus, the goal of this study was to evalu...


    pub_type: 杂志文章


    authors: Wu D,Li C,Chen Y,Xiong H,Tian X,Wu W,Huang W,Zhang YT,Zhang H

    更新日期:2016-06-01 00:00:00

  • D-lactic acidosis. A review of clinical presentation, biochemical features, and pathophysiologic mechanisms.

    abstract::This report describes a case of d-lactic acidosis observed by the authors and then reviews all case reports of d-lactic acidosis in the literature in order to define its clinical and biochemical features and pathogenetic mechanisms. The report also reviews the literature on metabolism of d-lactic acid in humans. The c...


    pub_type: 杂志文章,评审


    authors: Uribarri J,Oh MS,Carroll HJ

    更新日期:1998-03-01 00:00:00

  • Lead poisoning in a 16-year-old girl: a case report and a review of the literature (CARE compliant).

    abstract:BACKGROUND:Lead is a toxic element of the environment which leads to major complications once it enters the blood stream, affecting multiple organs and systems of the body. METHODS:We present the case of a 16-year-old girl, diagnosed with lead poisoning after occupational exposure due to the fact that the girl was act...


    pub_type: 杂志文章,评审


    authors: Mărginean CO,Meliţ LE,Moldovan H,Lupu VV,Mărginean MO

    更新日期:2016-09-01 00:00:00

  • Extracorporeal shockwave therapy combined with multiple drilling and intramedullary drug injection for treating early-stage Femur Head Necrosis: Protocol for a randomized controlled trial.

    abstract:BACKGROUND:Early diagnosis and treatment of the osteonecrosis of the femoral head (ONFH), a refractory disease, is imperative to prevent femoral head collapse; however, the existing solutions remain controversial. This study assessed the safety and efficacy of extracorporeal shock wave therapy (ESWT) combined with mult...


    pub_type: 杂志文章,随机对照试验


    authors: Li Q,Chen R,Yu Y,Wang X,Feng X,Jiang L,Chen B,Xin P,Li T,Shi Y,Jian Q,Jiang Z,Fan X

    更新日期:2020-10-02 00:00:00

  • Management and outcomes of spinal epidural hematoma during vertebroplasty: Case series.

    abstract:RATIONALE:Spinal cord injury (SCI) is one of the common complications of spinal surgery. There is no definite treatment and time of decompression for spinal cord induced by epidural hematoma during vertebroplasty. PATIENT CONCERNS:A total of 6 patients with SCI during vertebroplasty were included in our research. All ...


    pub_type: 杂志文章


    authors: Fang M,Zhou J,Yang D,He Y,Xu Y,Liu X,Zeng Y

    更新日期:2018-05-01 00:00:00

  • A case report of lupus erythematosus tumidus converted from discoid lupus erythematosus.

    abstract:RATIONALE:Lupus erythematosus tumidus (LET) is an uncommon type of cutaneous lupus erythematosus (CLE) that is rarely associated with other forms of lupus erythematosus. PATIENT CONCERNS:We report a 62-year-old Chinese man presented with recurrent erythematous facial plaques for 1 year and a low-grade fever for 1 week...


    pub_type: 杂志文章


    authors: Chen X,Wang S,Li L

    更新日期:2018-04-01 00:00:00

  • Contrast-enhanced ultrasound for determining muscular perfusion after oral intake of L-citrulline, L-arginine, and galloylated epicatechines: A study protocol.

    abstract:INTRODUCTION:The market for dietary supplements in the sports sector has been growing rapidly for several years, though there is still lacking evidence regarding their claimed benefits. One group is that of nitric oxide increasing supplements, so-called "NO-boosters," which are claimed to improve the supply of oxygen a...


    pub_type: 杂志文章


    authors: Doll J,Bürkle F,Neide A,Tsitlakidis S,Bruckner T,Schmidmaier G,Fischer C

    更新日期:2020-10-09 00:00:00

  • Splenic abscess owing to cancer at the splenic flexure: A case report and comprehensive review.

    abstract:BACKGROUND:The cancer of the splenic flexure of the colon is a rare medical entity with severe morbidity because of its insidious onset. METHODS:We present the case of a 59-year-old male patient with dull left upper quadrant pain, leukocytosis, and anemia. A splenic abscess described as an air-fluid level with splenoc...


    pub_type: 杂志文章,评审


    authors: Awotar GK,Luo F,Zhao Z,Guan G,Ning S,Ren J,Liu Y,Wang G,Liu P

    更新日期:2016-09-01 00:00:00

  • Complications after spinal anesthesia in adult tethered cord syndrome.

    abstract::Since little has been reported about complications of spinal anesthesia in adult tethered cord syndrome (TCS), we sought to delineate the characteristics of the condition.A total of 4 cases of adult TCS after spinal anesthesia were reviewed. The medical charts of the patients were obtained. Anesthesia, which was combi...


    pub_type: 杂志文章


    authors: Liu JJ,Guan Z,Gao Z,Xiang L,Zhao F,Huang SL

    更新日期:2016-07-01 00:00:00

  • Relationship between the self-concept and physical activity towards the prevention of chronic illnesses.

    abstract::The objective of this work is to verify the relationship between the self-perception of health and the self-concept of physical appearance in adolescents, in order to check their influence on the physical activity they perform with the aim of preventing chronic illnesses. To this end, an observational, cross-sectional...


    pub_type: 杂志文章


    authors: Duarte-Clíments G,Sánchez-Gómez MB,Palenzuela-Luis N,González-Abreu J,Guzmán-Fernández CJ,Ramos-Santana S,Gómez-Salgado J,Rodríguez-Gómez JÁ,Romero-Martín M

    更新日期:2020-07-10 00:00:00

  • Prevalence of adjacent segment disease following cervical spine surgery: A PRISMA-compliant systematic review and meta-analysis.

    abstract:UNLABELLED:Prevalence estimates of adjacent segment degeneration (ASD) following cervical spine surgery varied greatly in current studies. We conducted a systematic review and meta-analysis to summarize the point prevalence of ASD after cervical spine surgery. METHODS:Comprehensive electronic searches of PubMed, Embas...


    pub_type: 杂志文章,meta分析,评审


    authors: Kong L,Cao J,Wang L,Shen Y

    更新日期:2016-07-01 00:00:00

  • Favorable glycemic response after pancreatoduodenectomy in both patients with pancreatic cancer and patients with non-pancreatic cancer.

    abstract::Diabetes mellitus (DM) is prevalent in patients with pancreatic cancer and tends to improve after tumor resection. However, the glycemic response of non-pancreatic cancer patients after surgery has not been examined in detail. We aimed to investigate the changes in glucose metabolism in patients with pancreatic cancer...


    pub_type: 杂志文章


    authors: Sohn SY,Lee EK,Han SS,Lee YJ,Hwangbo Y,Kang YH,Lee SD,Kim SH,Woo SM,Lee WJ,Hong EK,Park SJ

    更新日期:2018-05-01 00:00:00

  • The effect of intra-articular stimulation by pulsed radiofrequency on chronic sacroiliac joint pain refractory to intra-articular corticosteroid injection: A retrospective study.

    abstract::We investigated the degree of pain reduction following intra-articular (IA) pulsed radiofrequency (PRF) stimulation of the sacroiliac joint (SIJ) in patients with chronic SIJ pain that had not responded to IA corticosteroid injection. Twenty patients were recruited. Clinical outcomes after applying PRF stimulation of ...


    pub_type: 杂志文章


    authors: Chang MC,Ahn SH

    更新日期:2017-06-01 00:00:00

  • A retrospective study of in-hospital mortality in patients with idiopathic pulmonary fibrosis between 2015 and 2018.

    abstract::Hospitalizations are common in patients with idiopathic pulmonary fibrosis (IPF) and are associated with high mortality. We used data from the Premier Healthcare Database to determine in-hospital mortality rates and the factors associated with in-hospital mortality in patients with IPF in the era of approved antifibro...


    pub_type: 杂志文章


    authors: Durheim MT,Judy J,Bender S,Neely ML,Baumer D,Robinson SB,Conoscenti CS,Leonard TB,Lazarus HM,Palmer SM

    更新日期:2020-11-20 00:00:00

  • Dramatic thrombolysis after rapid injection of tissue plasminogen activator: A case report.

    abstract:RATIONALE:The regimen of the recombinant tissue plasminogen activator (rt-PA) is identical in every case where it is indicated in the treatment of cerebral infarction. We report a case of efficient recanalization of large arterial occlusion after rapid injection of rt-PA. PATIENT CONCERNS:A 78-year-old man was admitte...


    pub_type: 杂志文章


    authors: Park JS,Hwang J

    更新日期:2019-09-01 00:00:00

  • PRISMA--efficacy and safety of vedolizumab for inflammatory bowel diseases: a systematic review and meta-analysis of randomized controlled trials.

    abstract::Vedolizumab is an anti-inflammatory monoclonal antibody that exclusively targets the α4β7 integrin. We aimed to systematically review the efficacy and safety of vedolizumab for patients with inflammatory bowel diseases (IBDs). PubMed, EMBASE, and the Cochrane Library were searched up to May 2014. Randomized controlled...


    pub_type: 杂志文章,meta分析,评审


    authors: Wang MC,Zhang LY,Han W,Shao Y,Chen M,Ni R,Wang GN,Wei FX,Zhang YW,Xu XD,Zhang YC

    更新日期:2014-12-01 00:00:00

  • Application of deep learning (3-dimensional convolutional neural network) for the prediction of pathological invasiveness in lung adenocarcinoma: A preliminary study.

    abstract::To compare results for radiological prediction of pathological invasiveness in lung adenocarcinoma between radiologists and a deep learning (DL) system.Ninety patients (50 men, 40 women; mean age, 66 years; range, 40-88 years) who underwent pre-operative chest computed tomography (CT) with 0.625-mm slice thickness wer...


    pub_type: 杂志文章


    authors: Yanagawa M,Niioka H,Hata A,Kikuchi N,Honda O,Kurakami H,Morii E,Noguchi M,Watanabe Y,Miyake J,Tomiyama N

    更新日期:2019-06-01 00:00:00

  • Increased APRIL Expression Induces IgA1 Aberrant Glycosylation in IgA Nephropathy.

    abstract::Aberrant glycosylated IgA1 molecules, mainly galactose-deficient IgA1 (Gd-IgA1), are important causal factors in IgA nephropathy; however, the underlying mechanism for the production of aberrantly glycosylated IgA1 is unknown. A recent genome-wide association study identified a novel IgAN susceptibility gene, TNFSF13,...


    pub_type: 杂志文章


    authors: Zhai YL,Zhu L,Shi SF,Liu LJ,Lv JC,Zhang H

    更新日期:2016-03-01 00:00:00

  • Pulmonary edema following shoulder arthroscopy under general anesthesia with nerve block: An observational study.

    abstract:ABSTRACT:Shoulder arthroscopy requires a large of irrigation for a better surgical view, leading circulatory overload. This study was performed to prove whether pulmonary edema will be lead by a large of irrigation.General anesthesia with interscalene block was induced before operation. The primary outcome was ultrasou...


    pub_type: 杂志文章


    authors: Zhang G,Wan Q,Huang X,Shui Y,Luo C,Su L,Jiang X,Zhang L

    更新日期:2020-12-18 00:00:00

  • Behavioral problems of Mandarin-speaking late-talking toddlers and preschool aged children: A prospective case-control study in Taiwan.

    abstract::This study aimed to examine whether Mandarin-speaking late-talking (LT) toddlers have a higher incidence of behavioral problems than typical language developing (TLD) children in toddlerhood and at preschool age from a community sample in Taiwan.This prospective case-control study comprised 32 LT and 32 TLD toddlers. ...


    pub_type: 杂志文章


    authors: Lu HH,Tsao FM,Tsai JD

    更新日期:2020-11-25 00:00:00