Abstract：
BACKGROUND:Some patients with ongoing heart failure symptoms after treatment with cardiac resynchronization therapy (CRT) demonstrate QRS prolongation during exercise. We investigated whether the optimal CRT pacing configuration changes during dobutamine stress. METHODS:Seven patients undergoing CRT implantation underwent invasive LV dP/dTmax measurement during CRT pacing in 10 configurations to determine the optimal baseline pacing configuration (OPC). Measurements were repeated during dobutamine infusion. Differences in mean LV dP/dTmax between pacing configurations were compared. RESULTS:Baseline OPC differed from stress OPC in 6/7 patients. The mean (SD) LV dP/dTmax obtained during dobutamine infusion was 1140 (377) mmHg/s in AAI pacing, 1458 (448) mmHg/s in the baseline OPC, and 1656 (435) mmHg/s in the dobutamine OPC (p < 0.001 for differences). The mean increase in LV dP/dTmax obtained by changing from baseline OPC to dobutamine OPC during dobutamine infusion was 197 (338) mmHg/s (13%). The QRS duration, QRS morphology, QLV and QRV intervals did not change significantly during dobutamine infusion (all P > 0.05). CONCLUSIONS:The optimal CRT pacing configuration changes during dobutamine infusion while LV and RV activation timing does not. Further studies investigating the usefulness of automated dynamic changes to CRT pacing configuration according to physiologic condition may be warranted.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Atwater BD,Jones WS,Loring Z,Friedman DJdoi
10.1016/j.jelectrocard.2020.08.012subject
Has Abstractpub_date
2020-01-01 00:00:00pages
124-128eissn
0022-0736issn
1532-8430pii
S0022-0736(20)30532-Xjournal_volume
62pub_type
杂志文章abstract：BACKGROUND:Presence of severe autonomic failure (SAF), defined as coincidence of abnormal heart rate turbulence and abnormal deceleration capacity, identifies a group of patients with very poor prognosis among post-infarction patients with diabetes mellitus. However, factors contributing to development of SAF are entir...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2012.07.010
更新日期：2012-11-01 00:00:00
abstract：:A prolonged QT interval is an important prognostic indicator for cardiac arrhythmias and sudden death. The conventional QT interval measurement, however, includes in its measure the cardiac depolarization (QRS) as well as the cardiac repolarization (JT) intervals. To evaluate the relative contribution of the depolariz...
journal_title：Journal of electrocardiology
pub_type： 临床试验,杂志文章
doi：10.1016/0022-0736(90)90150-z
更新日期：1990-01-01 00:00:00
abstract：:Serial ECG's were reviewed in 93 consecutive patients who were proven to be susceptible to malignant hyperthermia by caffeine contracture and ATP depletion tests on skeletal muscle biopsies, but who were without a history of pyrexic crises. There were 46 males and 47 females with a mean age of 33 years. Abnormal ECG's...
journal_title：Journal of electrocardiology
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doi：10.1016/s0022-0736(82)80007-1
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abstract：:We present a case of a woman with an asymptomatic intermittent 2:1 atrioventricular block. The baseline ECG showed a wide QRS with right bundle branch block pattern. Measurement of the HV interval during electrophysiological study was normal. During electrophysiological stimulation, a unique pattern of paradoxical con...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2017.03.003
更新日期：2017-01-01 00:00:00
abstract：:One common variety of exercise-induced artifact is baseline wander resulting from movement, respiration, and poor electrode contact. Although filters can be designed to remove much of this baseline variation, they will distort the low-frequency components of the ECG complex, such as the TP-segment, the PR-segment, and...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(88)90083-0
更新日期：1988-01-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2015.04.001
更新日期：2015-07-01 00:00:00
abstract：:The contributions of reduced conduction velocity (CV) and prolonged action potential duration (APD) to QT interval prolongation and T wave and T vector loop morphology in left ventricular hypertrophy (LVH) were studied using an analytical computer model. Three types of anatomic LVH were simulated: concentric and eccen...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2010.07.005
更新日期：2010-11-01 00:00:00
abstract：:Initial electrical forces emanating from interventricular septal depolarization, being directed to the right and anteriorly, normally produce an initial negative deflection or Q wave in leads I, aVL and V6 and an initial positive deflection or R wave in leads V1 and V2. The observations of hypertrophied interventricul...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(81)80044-1
更新日期：1981-01-01 00:00:00
abstract：BACKGROUND:Ventricular arrhythmias and sudden cardiac deaths are the most common cause of mortality in patients with end-stage renal disease (ESRD). Index of cardiac-electrophysiological balance (iCEB) (QT/QRS) may predict malignant ventricular arrhythmias. In this study, we investigated whether iCEB value is increased...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2019.03.011
更新日期：2019-01-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(96)80082-3
更新日期：1996-07-01 00:00:00
abstract：:Severe bradyarrythmias remain as an important cause for hospital urgent admission and these patients can suffer potentially lethal complications (such as ventricular fibrillation [VF] and torsades de pointes [TdP]) between hospital admission and final therapy. Incidence and predictors of these tachyarrhythmias have no...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2003.10.003
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:While J-waves were observed in healthy populations, variations in their reported incidence may be partly explicable by the ECG filter setting. METHODS:We obtained resting 12-lead ECG recordings in 665 consecutive patients and enrolled 112 (56 men, 56 women, mean age 59.3±16.1years) who manifested J-waves on...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2013.10.001
更新日期：2014-01-01 00:00:00
abstract：AIM:P-wave dispersion (PD), and duration has been reported to be associated with inhomogeneous and discontinuous propagation of sinus impulses. The aim of this study was to investigate the PD in patients with coronary slow flow (CSF) phenomenon. METHODS:Study population included 48 patients with angiographically prove...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2006.06.004
更新日期：2008-01-01 00:00:00
abstract：UNLABELLED:The increased QRS voltage is considered to be a specific electrocardiogram (ECG) sign of left ventricular hypertrophy (LVH), and it is expected that the QRS voltage reflects the increase in left ventricular mass (LVM). However, the increased QRS voltage is only one of QRS patterns observed in patients with L...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2009.07.014
更新日期：2010-05-01 00:00:00
abstract：:The addition of propranolol to mexiletine may reduce the adverse effects of mexiletine and possibly increase its efficacy. We compared the cellular electrophysiologic effects of this combination with mexiletine and propranolol alone, over concentration ranges of 3.2 to 100 microM mexiletine and 0.80 to 25.0 microM pro...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(87)80080-8
更新日期：1987-11-01 00:00:00
abstract：:Signal-averaged electrocardiogram (ECG) variables were analyzed in 81 patients with ventricular tachyarrhythmia and nonischemic heart disease using the ART LVP 101 EPX system (Austin, TX): 15 ventricular tachycardia patients with arrhythmogenic right ventricular dysplasia (ARVD), 7 ventricular tachycardia patients wit...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(94)80091-x
更新日期：1994-01-01 00:00:00
abstract：:The American College of Cardiology recommends that patients with high risk acute myocardial infarction (AMI) be triaged to hospitals with percutaneous transluminal coronary angioplasty capability. However, there are no prehospital triage criteria to select candidates for bypassing community hospitals and being taken d...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1054/jelc.2000.20299
更新日期：2000-01-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2009.03.011
更新日期：2009-09-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1054/jelc.2000.20330
更新日期：2000-01-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(82)81002-9
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journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1054/jelc.2001.28859
更新日期：2001-01-01 00:00:00
abstract：:From a population of 304 patients who were operated on for atrial septal defects, 25 patients with primum defects and 78 patients with secundum defects were studied with regard to the ability of various quantitative axial lead vectorcardiographic (VCG) data to predict the anatomical type of defect. The patients includ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(75)80023-9
更新日期：1975-01-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(86)80012-7
更新日期：1986-01-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(89)90037-x
更新日期：1989-07-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2006.05.026
更新日期：2006-10-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2012.04.003
更新日期：2012-07-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2008.07.022
更新日期：2008-11-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1016/s0022-0736(99)90022-5
更新日期：1999-01-01 00:00:00
abstract：:A comparison was performed between the points measured using the Selvester QRS scoring system in 60 electrocardiograms (ECGs) displayed in both a standard format as well as a 4-fold magnified (quad-plot) format. Fifty criteria (a maximum possibility of 31 points) were evaluated in each ECG. The data indicate that in 5...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2006.07.008
更新日期：2007-07-01 00:00:00
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journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2016.08.010
更新日期：2016-01-01 00:00:00
