Altered gene expression profiles of testicular tissues from azoospermic patients with maturation arrest.

abstract：:This study was conducted to evaluate the effects of ivermectin (IVM) with therapeutic dose (injected with 0.56 mg/kg b.wt.) either alone or combined with alpha lipoic acid (ALA) (50 mg/kg b.wt daily) on expression of testicular insulin-like growth factor binding protein-3 (IGFBP-3) and heat-shock protein A1 (HSPA1)) g...

journal_title：Andrologia

authors： El-Maddawy ZK,Abd El Naby WSH

更新日期：2018-04-01 00:00:00

abstract：:Although feeding diets containing the extract powder of Lepidium meyenii (maca), a plant growing in Peru's Central Andes, increases serum testosterone concentration associated with enhanced ability of testosterone production by Leydig cells in male rats, changes in testicular steroidogenesis-related factors by the mac...

journal_title：Andrologia

authors： Ohta Y,Kawate N,Inaba T,Morii H,Takahashi K,Tamada H

更新日期：2017-12-01 00:00:00

abstract：:After a single injection of serum gonadotrophin (PMSG) at the dose of 15 IU/kg, i.m. into rams testosterone in the plasma of blood showed a significant rise between 4th and 7th day post-injection. At the same time (4th-7th day) the plasminogen activator activity (PAA) in seminal plasma was found to be increased, but t...

journal_title：Andrologia

authors： Rekkas C,Belibasaki S,Taitzoglou I,Kokolis N,Smokovitis A

更新日期：1991-07-01 00:00:00

abstract：:An estrogen binding protein has been demonstrated in the cytosol of the epididymis and caudal lobe of prostate of immature rhesus monkey. Scatchard plot analyses were linear, suggesting a single class of high affinity binding sites for the synthetic estrogen, R-2858 (Moxestrol) with a Kd of 5.88 X 10(-10) mol/l and a ...

journal_title：Andrologia

authors： Kamal N,Agarwal AK,Jehan Q,Setty BS

更新日期：1985-07-01 00:00:00

abstract：:Steroid hormone progesterone has been found to play an important role in the migration of spermatozoa through the reproductive tract, as well as to induce hyperactive motility and increase sperm velocity. The aim of this study was to examine whether progesterone could induce beneficial effects in vitrified and slow-fr...

journal_title：Andrologia

authors： Saymé N,Dite L,Krebs T,Kljajić M,Maas DHA

更新日期：2018-12-01 00:00:00

abstract：:The Aurora kinases regulate chromosome segregation and cytokinesis, and alterations in their expression associate with cell malignant transformation. In this study, we demonstrated by qRT-PCR analysis of 14 seminomas that Aurora-A mRNA was, with respect to control tissues, augmented in five of 14 tumour tissues by 2.1...

journal_title：Andrologia

authors： Baldini E,Arlot-Bonnemains Y,Mottolese M,Sentinelli S,Antoniani B,Sorrenti S,Salducci M,Comini E,Ulisse S,D'Armiento M

更新日期：2010-08-01 00:00:00

abstract：:This study was aimed at determining the effects of corn and wheat gluten, used as dietary protein sources, on live weight gain, sperm quality and the histology of the testes and accessory glands in male rats. For this purpose, 20-day-old 24 male Wistar albino rats were randomly assigned to three groups. Group 1 (Contr...

journal_title：Andrologia

authors： Gumus R,Uslu S,Uslu BA

更新日期：2020-07-01 00:00:00

abstract：:Methylenetetrahydrofolate reductase (MTHFR), the key enzyme of the folate metabolic pathway, has been reported to be five times more active in the testicles compared to other organs in adult mice. The aim of this study was to investigate the relationship between MTHFR c.677C>T and c.1298A>C polymorphisms and infertili...

journal_title：Andrologia

authors： Gurkan H,Tozkır H,Göncü E,Ulusal S,Yazar M

更新日期：2015-11-01 00:00:00

abstract：:The effects of incubation with caffeine at final concentration of 0.5 and 5.0 mM for 30 min at ambient temperature were examined in three normal semen samples and three from asthenozoospermic men. A 50 frames/s microcinematographic analysis of the sperm motility was performed and two characteristic parameters of the t...

journal_title：Andrologia

authors： Serres C,Feneux D,David G

更新日期：1982-09-01 00:00:00

abstract：:Varicocele is one of the leading causes of male infertility in which oxidative stress induces DNA damages in spermatozoa of patients with varicocele. Recent studies indicated that the treatment with antioxidant agents has protective effects against the formation of reactive oxygen species (ROS). Our research aimed to ...

journal_title：Andrologia

authors： Dolatkhah MA,Shokoohi M,Charvandeh S,Tvrda E,Shoorei H,Moghimian M,Alihemmati A

更新日期：2020-12-01 00:00:00

abstract：:Previous studies have found that the ratio of estradiol to testosterone (E2/T ratio) has a negative effect on sexual function, but the relationship between the E2/T ratio and erection of the penis is not clarified. We conducted a retrospective study of 183 patients with erectile dysfunction and 52 healthy men to inves...

journal_title：Andrologia

authors： Pan D,Xu ZH,Gao Q,Li M,Guan Y,Zhao ST

更新日期：2020-10-01 00:00:00

abstract：:Sertoli-cell-only (SCO) syndrome, or germ cell aplasia, is diagnosed on testicular biopsy when germ cells are seen to be absent without histological impairment of Sertoli or Leydig cells. It is considered a situation of irreversible infertility. Recent studies have shown that varicocele, a bilateral disease, causes hy...

journal_title：Andrologia

authors： Gat Y,Gornish M,Perlow A,Chakraborty J,Levinger U,Ben-Shlomo I,Pasqualotto F

更新日期：2010-10-01 00:00:00

abstract：:In this study we investigated the relationship between personality attitudes, psychopathological symptoms and biological parameters in male infertility. Eighty-four infertile men underwent a psychological and medical examination at our clinic. The psychological tests comprised the Symptom Checklist 90-R, the Toronto A...

journal_title：Andrologia

authors： Conrad R,Schilling G,Haidl G,Geiser F,Imbierowicz K,Liedtke R

更新日期：2002-10-01 00:00:00

abstract：:Studies assessing the efficacy of intralesional verapamil injection in the treatment of Peyronie's disease have yielded mixed results. The purpose of this meta-analysis is to systematise the existing literature on the efficacy of intralesional verapamil injection when used in the treatment of Peyronie's disease. The t...

journal_title：Andrologia

authors： Sadagopan A

更新日期：2019-11-01 00:00:00

abstract：:Male rats ten days of age were divided in three groups: a) hemicastrated, b) sham operated and c) control. They were daily sacrificed between 30 and 50 days of age. Wet weight and dry weight were determined in testis, seminal vesicles and epididymis. The concentration of spermatozoa was measured in testis and caput ep...

journal_title：Andrologia

authors： Santolaya RC,Burgos MH

更新日期：1978-01-01 00:00:00

abstract：:Altered protamine 1 (PRM1)/ protamine 2 (PRM2) mRNA ratio in testicular biopsy samples correlates with sperm quality and its fertilising ability. This study is planned to assess PRM1/ PRM2 mRNA ratio in subgroups of azoospermia to suggest a more reliable and accurate marker for assessing sperm quality in nonobstructiv...

journal_title：Andrologia

authors： Amjad S,Mushtaq S,Rehman R,Munir A,Zahid N,Siddique PQR

更新日期：2021-01-11 00:00:00

abstract：:Retraction: 'Aetiology and clinical profile of children with 46, XY differences of sex development at an Indian referral centre' by Vasundhera Chauhan, Rima Dada, Vandana Jain The above article, published online on 8 August 2016 in Wiley Online Library (http://wileyonlinelibrary.com), has been retracted by agreement b...

journal_title：Andrologia

authors： Chauhan V,Dada R,Jain V

更新日期：2017-11-01 00:00:00

abstract：:This study investigated the effects of rutin against reproductive damage caused by toxic mercury in male rats. Thirty-five Sprague Dawley rats were used. Control group was injected with saline for 7 days. The rutin-100 group received 100 mg/kg/b.w. rutin for 7 days. Mercuric chloride (HgCl2 ) group received 1.23 mg/kg...

journal_title：Andrologia

authors： Kandemir FM,Caglayan C,Aksu EH,Yildirim S,Kucukler S,Gur C,Eser G

更新日期：2020-04-01 00:00:00

abstract：:The pre-operative treatment of three adult male transsexuals with the anti-androgen and progestogenic compound cyproterone acetate is reported. When used in combination with cyproterone acetate, only a very small dose of oestrogen is needed to induce feminisation. The effect of this treatment on both testicular and ep...

journal_title：Andrologia

authors： Jequier AM,Bullimore NJ,Bishop MJ

更新日期：1989-09-01 00:00:00

abstract：:Varicocele is one of causes of the declined sperm quality and low sperm production, which can lead to infertility in males. There are several experimental and epidemiological findings which support the idea that inflammatory mechanisms play an essential role in varicocele pathogenesis. Besides, in this pathological st...

journal_title：Andrologia

authors： Zeinali M,Hadian Amree A,Khorramdelazad H,Karami H,Abedinzadeh M

更新日期：2017-08-01 00:00:00

abstract：:The Fas system is involved in the control of immune system homeostasis and nonfunctional Fas system leads to autoimmune disease in mice and humans. The Fas system is a mechanism through which cells expressing Fas ligand (FasL) induce apoptosis of Fas expressing cells. In mouse and rat, the testis represents the main s...

journal_title：Andrologia

authors： Riccioli A,Salvati L,D'Alessio A,Starace D,Giampietri C,De Cesaris P,Filippini A,Ziparo E

更新日期：2003-02-01 00:00:00

abstract：:The scope of this study was to evaluate the accuracy, precision and specificity of the sperm concentration measurements by the Strömberg-Mika Cell Motion Analyser (SM-CMA). Our data show that the instrument generally underscores the sperm concentration and therefore the uncorrected measurements must be corrected by th...

journal_title：Andrologia

authors： Togni G,Gallicciotti G,Coccia P,Piffaretti-Yanez A,Stamm J,Balerna M

更新日期：1995-01-01 00:00:00

abstract：:The study was performed to measure the impact of testosterone (T) administration on circulating levels of 5alpha-dihydrotestosterone (DHT). Group 1 (32 men; mean age 61 years; mean T 6.9 +/- 1.9 nmol l(-1)) were treated for 15 months with long-acting T undecanoate. Group 2 (23 men, mean age 60 years, mean T 7.6 +/- 2....

journal_title：Andrologia

authors： Gooren LJ,Saad F,Haide A,Yassin A

更新日期：2008-10-01 00:00:00

abstract：:Human chorionic Gonadotropin (HCG) therapy has been used beneficially in men with subfertility especially after varicocele surgery. Very few side effects have been observed in male patients. Herein, we report a case of pulmonary embolism in a male patient following the use of HCG. The patient was subsequently found to...

journal_title：Andrologia

authors： Dhabuwala CB,Kumar A,Pierce JM

更新日期：1987-01-01 00:00:00

abstract：:The spontaneous acrosomal reaction of mouse spermatozoa during their passage through the male and female genital tract was studied by indirect immunofluorescence staining techniques using antibodies against the outer acrosomal membrane (OAM). Low rates of spontaneously acrosome-reacted spermatozoa could be observed du...

journal_title：Andrologia

authors： Klemm M,Engel W

更新日期：1991-11-01 00:00:00

abstract：:This study has been conducted to investigate the effect of hesperidin on colistin-induced reproductive damage in male rats. Twenty-four adult male Sprague Dawley rats were used as animal material. They were divided into four groups: control group, received physiological saline for 7 days by oral gavage; hesperidin gro...

journal_title：Andrologia

authors： Aksu EH,Kandemir FM,Küçükler S

更新日期：2020-12-01 00:00:00

abstract：:The lipid composition of the sperm membrane has been shown to exert a significant effect upon the functional quality of spermatozoa. We have studied fatty acid composition of the phospholipids in spermatozoa in asthenozoospermic and normozoospermic men and determined the ratio of polyunsaturated fatty acids (PUFAs) to...

journal_title：Andrologia

authors： Tavilani H,Doosti M,Abdi K,Vaisiraygani A,Joshaghani HR

更新日期：2006-10-01 00:00:00

abstract：:The metabolism of nine radioactively labeled steroids in the epithelium of the seminal vesicle of the mature guinea pig has been studied. The rapid assimilation and metabolism of these steroids demostrate the very active biochemical nature of this tissue. Based on the use of several thin-layer chromatography systems a...

journal_title：Andrologia

authors： Steer RC,Veneziale CM

更新日期：1977-04-01 00:00:00

abstract：:The aim of the study was to investigate whether or not the effect of icariin on erectile function of SHR is associated with inhibition of eNOS uncoupling. Ten 12-week-old male WKY rats and 10 age-matched male SHR were evenly randomised into SHR control group, SHR+ icariin treatment group, WKY control group and WKY+ ic...

journal_title：Andrologia

authors： Long H,Jiang J,Xia J,Jiang R

更新日期：2018-11-01 00:00:00

abstract：:Several drugs have been used to stimulate human sperm motility, including 3-deoxy-adenosine, caffeine, and pentoxifylline. Pentoxifylline is an inhibitor of the phosphodiesterase and may stimulate sperm motility by increasing the intracellular levels of cAMP. In this study we have evaluated the effect of pentoxifyllin...

journal_title：Andrologia

authors： Morales P,Llanos M,Yovich JL,Cummins JM,Vigil P

更新日期：1993-11-01 00:00:00