Staphylococcus Aureus Panton-Valentine Leukocidin causing hip osteomyelitis, thrombophlebitis and necrotizing pneumonia in an immuocompetent child.

Abstract:

:Panton-Valentine leukocidin (PVL) represents an important virulence factor for many strains of Staphylococcus aureus. PVL is an esotoxin causing leucocyte destruction and tissue necrosis. We report on a case of osteomyelitis involving the hip joint with thromblophlebitis complicated by necrotizing pneumonia and life-threatening septic shock. The child required advance respiratory support for 14 days with circulatory support for 7 days in ICU (intensive care unit), surgical draninage via arthrotomy of hip joint and second-line antibiotic treatment for 1 month. Among a wide literature, in Europe over half of Panton-Valentine St. Aureus (PVL-SA) is MSSA. Investigations for PVL are not always available determining an under-recognition of the episodes. Data on prevalence of PVL-SA in Italy are scarce. With this clinical report, we emphasize the recognition of clinical features that must lead to suspect PVL-SA osteomyelitis in children, providing their adequate management.

authors

ADVANCES IN MUSCULOSKELETAL DISEASES AND INFECTIONS - SOTIMI 2019:.,Cori MS,Ronconi G,Masiello E,Valentini P,Ferriero G,Maccauro G,Ferrara PE

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

53-56

issue

3 Suppl. 2

eissn

0393-974X

issn

1724-6083

pii

8

journal_volume

34

pub_type

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