A newly isolated strain of Halomonas sp. (HA1) exerts anticancer potential via induction of apoptosis and G2/M arrest in hepatocellular carcinoma (HepG2) cell line.

abstract：:Bacterial communities from freshwater lakes are shaped by various factors such as nutrients, pH value, temperature, etc. Their compositions and relative abundances would undergo changes to adapt the changing environments, and in turn could affect the environments of freshwater lakes. Analyses of the freshwater lake's ...

journal_title：Scientific reports

authors： Han M,Gong Y,Zhou C,Zhang J,Wang Z,Ning K

更新日期：2016-07-27 00:00:00

abstract：:Phase distribution of emerging organic contaminants is highly influential in their presence, fate and transport in surface water. Therefore, it is crucial to determine their state, partitioning behaviour and tendencies in water environments. In this study, Bisphenol A was investigated in both colloidal and soluble pha...

journal_title：Scientific reports

authors： Shehab ZN,Jamil NR,Aris AZ

更新日期：2020-11-23 00:00:00

abstract：:The neurology of male sexuality has been poorly studied owing to difficulties in studying brain circuitry in humans. Dopamine (DA) is essential for both physiological and behavioural responses, including the regulation of sexuality. Previous studies have revealed that alterations in DA synthesis in dopaminergic neuron...

journal_title：Scientific reports

authors： Chen SL,Chen YH,Wang CC,Yu YW,Tsai YC,Hsu HW,Wu CL,Wang PY,Chen LC,Lan TH,Fu TF

更新日期：2017-03-15 00:00:00

abstract：:Current medications inadequately treat the symptoms of chronic pain experienced by over 50 million people in the United States, and may come with substantial adverse effects signifying the need to find novel treatments. One novel therapeutic target is the Transient Receptor Potential A1 channel (TRPA1), an ion channel...

journal_title：Scientific reports

authors： Ko MJ,Ganzen LC,Coskun E,Mukadam AA,Leung YF,van Rijn RM

更新日期：2019-02-20 00:00:00

abstract：:It remains unclear how infantile febrile seizures (FS) enhance adult seizure susceptibility. Here we showed that the transient increase of interleukin-1β (IL-1β) after prolonged FS promoted adult seizure susceptibility, which was blocked by interleukin-1 receptor antagonist (IL-1Ra) within a critical time window. Post...

journal_title：Scientific reports

authors： Feng B,Tang Y,Chen B,Xu C,Wang Y,Dai Y,Wu D,Zhu J,Wang S,Zhou Y,Shi L,Hu W,Zhang X,Chen Z

更新日期：2016-02-23 00:00:00

abstract：:New high-frequency 5G and satellite communication systems require fully-metallic antennas and electromagnetic components. These components can be implemented with truncated versions of periodic structures. In order to achieve the desired performance of these future devices, it is of crucial importance to have a precis...

journal_title：Scientific reports

authors： Ghasemifard F,Norgren M,Quevedo-Teruel O

更新日期：2018-07-26 00:00:00

abstract：:The vast majority of antibody-drug conjugates (ADC) are prepared through amine-to-thiol conjugation. To date, N-Succinimidyl-4-(maleimidomethyl) cyclohexanecarboxylate (SMCC) has been one of the most frequently applied reagents for the preparation of ADC and other functional conjugates. However, SMCC-based conjugates ...

journal_title：Scientific reports

authors： Dovgan I,Kolodych S,Koniev O,Wagner A

更新日期：2016-08-09 00:00:00

abstract：:We provide an explicit model for a spin-1/2 quasi-particle, based on the superposition of plasmon excitations in a quantum plasmas with intrinsic orbital angular momentum. Such quasi-particle solutions can show remarkable similarities with single electrons moving in vacuum: they have spin-1/2, a finite rest mass, and ...

journal_title：Scientific reports

authors： Mendonça JT,Serbeto A,Vieira J

更新日期：2018-05-18 00:00:00

abstract：:Immune-evasion and immune checkpoints are promising new therapeutic targets for several cancer entities. In ovarian cancer, the clinical role of programmed cell death receptor ligand 1 (PD-L1) expression as mechanism to escape immune recognition has not been clarified yet. We analyzed PD-L1 expression of primary ovari...

journal_title：Scientific reports

authors： Aust S,Felix S,Auer K,Bachmayr-Heyda A,Kenner L,Dekan S,Meier SM,Gerner C,Grimm C,Pils D

更新日期：2017-03-07 00:00:00

abstract：:Previous studies reported that boreal winter precipitation in southeastern China (SEC) tends to increase during El Niño. In this study, however, we find that most weak El Niño events are accompanied by below-normal precipitation in SEC, although strong El Niño events are accompanied by above-normal precipitation in SE...

journal_title：Scientific reports

authors： Ke Z,Jiang X,Wang Z

更新日期：2019-11-22 00:00:00

abstract：:Tupistra chinensis is widely distributed in southwestern China and its rhizome is a famous folk medicine for the treatment of carbuncles and pharyngitis. Its chemical identity of potent antiproliferative and anti-inflammatory constituents has been carried out in this study. Twenty-three polyhydroxylated spirostanol sa...

journal_title：Scientific reports

authors： Xiang L,Yi X,Wang Y,He X

更新日期：2016-08-17 00:00:00

abstract：:Human corneal endothelial cells (HCECs) easily become fibroblastic-like when cultured, rendering them unsuitable for tissue engineering of the cornea. Transforming growth factor β (TGF-β) could be a key factor in this phenomenon; however, TGF-β is also known to maintain the endothelium in a quiescent state in vivo. Th...

journal_title：Scientific reports

authors： Beaulieu Leclerc V,Roy O,Santerre K,Proulx S

更新日期：2018-03-13 00:00:00

abstract：:Developing therapeutics that target multiple receptor signaling pathways in tumors is critical as therapies targeting single specific biomarker/pathway have shown limited efficacy in patients with cancer. In this study, we extensively characterized a bi-functional molecule comprising of epidermal growth factor recepto...

journal_title：Scientific reports

authors： Zhu Y,Bassoff N,Reinshagen C,Bhere D,Nowicki MO,Lawler SE,Roux J,Shah K

更新日期：2017-06-01 00:00:00

abstract：:Functions of septin cytoskeletal polymers in tumorigenesis are still poorly defined. Their role in the regulation of cytokinesis and cell migration were proposed to contribute to cancer associated aneuploidy and metastasis. Overexpression of Septin 9 (Sept9) promotes migration of cancer cell lines. SEPT9 mRNA and prot...

journal_title：Scientific reports

authors： Verdier-Pinard P,Salaun D,Bouguenina H,Shimada S,Pophillat M,Audebert S,Agavnian E,Coslet S,Charafe-Jauffret E,Tachibana T,Badache A

更新日期：2017-03-24 00:00:00

abstract：:A sensitive and selective chemiluminescence (CL) sensor based on the peroxidase-like activity of copper nanoclusters was established for the detection of cholesterol. Copper nanoclusters catalyse the CL reaction between luminol and H2O2. Because H2O2 is the oxidative product of cholesterol in the presence of cholester...

journal_title：Scientific reports

authors： Xu S,Wang Y,Zhou D,Kuang M,Fang D,Yang W,Wei S,Ma L

更新日期：2016-12-14 00:00:00

abstract：:Compression of optical pulses to ultrashort pulse widths using methods of nonlinear optics is a well-established technology of modern laser science. Extending these methods to pulses with high peak powers, which become available due to the rapid progress of laser technologies, is, however, limited by the universal phy...

journal_title：Scientific reports

authors： Voronin AA,Zheltikov AM

更新日期：2017-04-03 00:00:00

abstract：:One key ability of human brain is invariant object recognition, which refers to rapid and accurate recognition of objects in the presence of variations such as size, rotation and position. Despite decades of research into the topic, it remains unknown how the brain constructs invariant representations of objects. Prov...

journal_title：Scientific reports

authors： Karimi-Rouzbahani H,Bagheri N,Ebrahimpour R

更新日期：2017-10-31 00:00:00

abstract：:Solution-processed gate dielectrics were fabricated with the combined ZrO2 and Al2O3 (ZAO) in the form of mixed and stacked types for oxide thin film transistors (TFTs). ZAO thin films prepared with double coatings for solid gate dielectrics were characterized by analytical tools. For the first time, the capacitance o...

journal_title：Scientific reports

authors： Kim H,Kwack YJ,Yun EJ,Choi WS

更新日期：2016-09-19 00:00:00

abstract：:The regeneration of WPAC through pyrolysis and its adsorption capacity of phosphorus were studied. The optimum conditions for WPAC regeneration were 650 °C and 2 h which resulted in a recovery of BET surface and total pore volume with a value of 1161.4 m2/g and 1.2176 m3/g. WPAC had a maximum PO43--P adsorption capaci...

journal_title：Scientific reports

authors： Li Y,Jin H,Liu W,Su H,Lu Y,Li J

更新日期：2018-01-15 00:00:00

abstract：:The discovery of the community structure of real-world networks is still an open problem. Many methods have been proposed to shed light on this problem, and most of these have focused on discovering node community. However, link community is also a powerful framework for discovering overlapping communities. Here we pr...

journal_title：Scientific reports

authors： Liu W,Jiang X,Pellegrini M,Wang X

更新日期：2016-03-01 00:00:00

abstract：:The placenta has emerged as an attractive source of mesenchymal stem cells (MSCs) because of the absence of ethical issues, non-invasive access, and abundant yield. However, inflammatory cell invasion into grafts negatively impacts the survival and efficacy of transplanted cells. Previous studies have shown that synth...

journal_title：Scientific reports

authors： Tian KW,Zhang YY,Jiang H,Han S

更新日期：2018-03-15 00:00:00

abstract：:In April 2012 we carried out a 1-year hematological study on a population of wild Japanese monkeys inhabiting the forest area of Fukushima City. This area is located 70 km from the Fukushima Daiichi Nuclear Power Plant (NPP), which released a large amount of radioactive material into the environment following the Grea...

journal_title：Scientific reports

authors： Ochiai K,Hayama S,Nakiri S,Nakanishi S,Ishii N,Uno T,Kato T,Konno F,Kawamoto Y,Tsuchida S,Omi T

更新日期：2014-07-24 00:00:00

abstract：:Acoustic manipulation by an ultrasonic phased array provides an entirely new approach to processes such as coalescence, mixing, separation, and evaporation occurring in the generation of new materials, physical property measurement, the biomedical industry, etc. However, to date, ultrasonic phased arrays have not been...

journal_title：Scientific reports

authors： Watanabe A,Hasegawa K,Abe Y

更新日期：2018-07-05 00:00:00

abstract：:Ambient seismic noise is characterized by randomness incurred by the random position and strength of the noise sources as well as the heterogeneous properties of the medium through which it propagates. Here we use ambient noise data recorded prior to the 1996 Gjálp eruption in Iceland in order to show that a reduction...

journal_title：Scientific reports

authors： Glynn CC,Konstantinou KI

更新日期：2016-11-24 00:00:00

abstract：:The aim was to investigate the ability of self-assembling Peptide P11-4 Matrix (SAPM) to remineralize artificial initial caries lesions compared to the use of fluoride varnish. Volunteers were recruited for this randomised, cross-over in situ trial. Bovine specimens, half including orthodontic brackets, were recessed ...

journal_title：Scientific reports

authors： Jablonski-Momeni A,Korbmacher-Steiner H,Heinzel-Gutenbrunner M,Jablonski B,Jaquet W,Bottenberg P

更新日期：2019-01-22 00:00:00

abstract：:The treatment of testicular cancer includes unilateral orchiectomy and chemotherapy and is curative for most patients. However, observational studies revealed an association with depression, anxiety and cognitive impairment. It is unclear whether these side effects are caused by chemotherapy, hemicastration or the dis...

journal_title：Scientific reports

authors： Borbélyová V,Renczés E,Chovanec M,Mego M,Celec P

更新日期：2020-06-23 00:00:00

abstract：:Enterohemorrhagic Escherichia coli (EHEC) are major food-borne pathogens whose survival and virulence in the human digestive tract remain unclear owing to paucity of relevant models. EHEC interact with the follicle-associated epithelium of Peyer's patches of the distal ileum and translocate across the intestinal epith...

journal_title：Scientific reports

authors： Cordonnier C,Etienne-Mesmin L,Thévenot J,Rougeron A,Rénier S,Chassaing B,Darfeuille-Michaud A,Barnich N,Blanquet-Diot S,Livrelli V

更新日期：2017-03-20 00:00:00

abstract：:Personal values developed in adolescence may influence mental health and well-being over the life course. Using data from 684 respondents in the Youth Development Study (61.9% of respondents in the baseline survey), we explored the effects of work values at ages 14-15 on positive and negative emotions, as well as psyc...

journal_title：Scientific reports

authors： Fukasawa M,Watanabe K,Nishi D,Kawakami N

更新日期：2020-08-11 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Paulino PG,Almosny N,Oliveira R,Viscardi V,Müller A,Guimarães A,Baldani C,da Silva C,Peckle M,Massard C,Santos H

更新日期：2020-07-29 00:00:00

abstract：:Predictive coding theories propose that the brain creates internal models of the environment to predict upcoming sensory input. Hierarchical predictive coding models of vision postulate that higher visual areas generate predictions of sensory inputs and feed them back to early visual cortex. In V1, sensory inputs that...

journal_title：Scientific reports

authors： Edwards G,Vetter P,McGruer F,Petro LS,Muckli L

更新日期：2017-11-28 00:00:00