Genetic architecture and genomic selection of female reproduction traits in rainbow trout.

abstract：BACKGROUND:Cryptic unstable transcripts (CUTs) are a largely unexplored class of nuclear exosome degraded, non-coding RNAs in budding yeast. It is highly debated whether CUT transcription has a functional role in the cell or whether CUTs represent noise in the yeast transcriptome. We sought to ascertain the extent of c...

journal_title：BMC genomics

authors： Vera JM,Dowell RD

更新日期：2016-04-26 00:00:00

abstract：BACKGROUND:Currently, diabetes has become one of the leading causes of death worldwide. Fasting plasma glucose (FPG) levels that are higher than optimal, even if below the diagnostic threshold of diabetes, can also lead to increased morbidity and mortality. Here we intend to study the magnitude of the genetic influence...

journal_title：BMC genomics

authors： Wang W,Zhang C,Liu H,Xu C,Duan H,Tian X,Zhang D

更新日期：2020-07-18 00:00:00

abstract：BACKGROUND:Oxidative stress is a consequence of normal and abnormal cellular metabolism and is linked to the development of human diseases. The effective functioning of the pathway responding to oxidative stress protects the cellular DNA against oxidative damage; conversely the failure of the oxidative stress response ...

journal_title：BMC genomics

authors： Sridharan S,Layek R,Datta A,Venkatraj J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Roche 454 pyrosequencing has become a method of choice for generating transcriptome data from non-model organisms. Once the tens to hundreds of thousands of short (250-450 base) reads have been produced, it is important to correctly assemble these to estimate the sequence of all the transcripts. Most transcr...

journal_title：BMC genomics

authors： Kumar S,Blaxter ML

更新日期：2010-10-16 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression implicated in multiple cellular processes. Cyclic stretch of alveoli is characteristic of mechanical ventilation, and is postulated to be partly responsible for the lung injury and inflammation in ventilator-induced lung injury. We pro...

journal_title：BMC genomics

authors： Yehya N,Yerrapureddy A,Tobias J,Margulies SS

更新日期：2012-04-26 00:00:00

abstract：BACKGROUND:Many gram-negative bacteria use type III secretion systems (T3SSs) to translocate effector proteins into host cells. T3SS effectors can give some bacteria a competitive edge over others within the same environment and can help bacteria to invade the host cells and allow them to multiply rapidly within the ho...

journal_title：BMC genomics

authors： Hobbs CK,Porter VL,Stow ML,Siame BA,Tsang HH,Leung KY

更新日期：2016-12-19 00:00:00

abstract：BACKGROUND:It is unclear whether improving feed efficiency by selection for low residual feed intake (RFI) compromises pigs' immunocompetence. Here, we aimed at investigating whether pig lines divergently selected for RFI had different inflammatory responses to lipopolysaccharide (LPS) exposure, regarding to clinical p...

journal_title：BMC genomics

authors： Liu H,Feye KM,Nguyen YT,Rakhshandeh A,Loving CL,Dekkers JCM,Gabler NK,Tuggle CK

更新日期：2019-10-11 00:00:00

abstract：BACKGROUND:Taraxacum kok-saghyz R. (Tks) is a promising alternative species to Hevea brasiliensis for production of high quality natural rubber (NR). A comparative transcriptome analysis of plants with differential production of NR will contribute to elucidate which genes are involved in the synthesis, regulation and a...

journal_title：BMC genomics

authors： Panara F,Lopez L,Daddiego L,Fantini E,Facella P,Perrotta G

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:Azadirachtin A is a triterpenoid from neem tree exhibiting excellent activities against over 600 insect species in agriculture. The production of azadirachtin A depends on extraction from neem tissues, which is not an eco-friendly and sustainable process. The low yield and discontinuous supply of azadirachti...

journal_title：BMC genomics

authors： Wang H,Wang N,Huo Y

更新日期：2020-10-28 00:00:00

abstract：BACKGROUND:Nicotiana attenuata (coyote tobacco) is an ecological model for studying plant-environment interactions and plant gene function under real-world conditions. During the last decade, large amounts of genomic, transcriptomic and metabolomic data have been generated with this plant which has provided new insight...

journal_title：BMC genomics

authors： Brockmöller T,Ling Z,Li D,Gaquerel E,Baldwin IT,Xu S

更新日期：2017-01-13 00:00:00

abstract：BACKGROUND:The environmental light-dark cycle is the dominant cue that maintains 24-h biological rhythms in multicellular organisms. In Drosophila, light entrainment is mediated by the photosensitive protein CRYPTOCHROME, but the role and extent of transcription regulation in light resetting of the dipteran clock is ye...

journal_title：BMC genomics

authors： Adewoye AB,Kyriacou CP,Tauber E

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Wheat is an excellent species to study freezing tolerance and other abiotic stresses. However, the sequence of the wheat genome has not been completely characterized due to its complexity and large size. To circumvent this obstacle and identify genes involved in cold acclimation and associated stresses, a la...

journal_title：BMC genomics

authors： Houde M,Belcaid M,Ouellet F,Danyluk J,Monroy AF,Dryanova A,Gulick P,Bergeron A,Laroche A,Links MG,MacCarthy L,Crosby WL,Sarhan F

更新日期：2006-06-13 00:00:00

abstract：BACKGROUND:We performed large-scale bacterial artificial chromosome (BAC) end-sequencing of two BAC libraries (an EcoRI- and a BamHI-digested library) and conducted an in silico analysis to characterize the obtained sequence data, to make them a useful resource for genomic research on the silkworm (Bombyx mori). RESUL...

journal_title：BMC genomics

authors： Suetsugu Y,Minami H,Shimomura M,Sasanuma S,Narukawa J,Mita K,Yamamoto K

更新日期：2007-09-07 00:00:00

abstract：BACKGROUND:Malaria pathogenesis relies on sexual gametocyte forms of the malaria parasite to be transmitted between the infected human and the mosquito host but the molecular mechanisms controlling gametocytogenesis remains poorly understood. Here we provide a high-resolution transcriptome of Plasmodium falciparum as i...

journal_title：BMC genomics

authors： van Biljon R,van Wyk R,Painter HJ,Orchard L,Reader J,Niemand J,Llinás M,Birkholtz LM

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:Numerous human genes encode potentially active DNA transposases or recombinases, but our understanding of their functions remains limited due to shortage of methods to profile their activities on endogenous genomic substrates. RESULTS:To enable functional analysis of human transposase-derived genes, we comb...

journal_title：BMC genomics

authors： Henssen AG,Jiang E,Zhuang J,Pinello L,Socci ND,Koche R,Gonen M,Villasante CM,Armstrong SA,Bauer DE,Weng Z,Kentsis A

更新日期：2016-08-04 00:00:00

abstract：BACKGROUND:Bacillus pumilus is a Gram-positive and endospore-forming bacterium broadly existing in a variety of environmental niches. Because it produces and secrets many industrially useful enzymes, a lot of studies have been done to understand the underlying mechanisms. Among them, scoC was originally identified as a...

journal_title：BMC genomics

authors： Han LL,Liu YC,Miao CC,Feng H

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND:Advances in whole genome profiling have revolutionized the cancer research field, but at the same time have raised new bioinformatics challenges. For next generation sequencing (NGS), these include data storage, computational costs, sequence processing and alignment, delineating appropriate statistical measu...

journal_title：BMC genomics

authors： Rodriguez BA,Frankhouser D,Murphy M,Trimarchi M,Tam HH,Curfman J,Huang R,Chan MW,Lai HC,Parikh D,Ball B,Schwind S,Blum W,Marcucci G,Yan P,Bundschuh R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The androgen receptor plays a critical role throughout the progression of prostate cancer and is an important drug target for this disease. While chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-Seq) is becoming an essential tool for studying transcription and chromatin modifica...

journal_title：BMC genomics

authors： Zhu Z,Shi M,Hu W,Estrella H,Engebretsen J,Nichols T,Briere D,Hosea N,Los G,Rejto PA,Fanjul A

更新日期：2012-07-31 00:00:00

abstract：BACKGROUND:One of the key characters of social insects is the division of labor, in which different tasks are allocated to various castes. In termites, one of the representative groups of social insects, morphological differences as well as behavioral differences can be recognized among castes. However, very little is ...

journal_title：BMC genomics

authors： Ishikawa Y,Okada Y,Ishikawa A,Miyakawa H,Koshikawa S,Miura T

更新日期：2010-05-20 00:00:00

abstract：BACKGROUND:Relationships between an organism and its environment can be fundamental in the understanding how populations change over time and species arise. Local ecological conditions can shape variation at multiple levels, among these are the evolutionary history and trajectories of coding genes. This study examines ...

journal_title：BMC genomics

authors： Allan CW,Matzkin LM

更新日期：2019-10-12 00:00:00

abstract：BACKGROUND:The most critical step in the pearl formation during aquaculture is issued to the proliferation and differentiation of outer epithelial cells of mantle graft into pearl sac. This pearl sac secretes various matrix proteins to produce pearls by a complex physiological process which has not been well-understood...

journal_title：BMC genomics

authors： Mariom,Take S,Igarashi Y,Yoshitake K,Asakawa S,Maeyama K,Nagai K,Watabe S,Kinoshita S

更新日期：2019-03-25 00:00:00

abstract：BACKGROUND:Over the past 50,000 years, shifts in human-environmental or human-human interactions shaped genetic differences within and among human populations, including variants under positive selection. Shaped by environmental factors, such variants influence the genetics of modern health, disease, and treatment outc...

journal_title：BMC genomics

authors： Handelman SK,Seweryn M,Smith RM,Hartmann K,Wang D,Pietrzak M,Johnson AD,Kloczkowski A,Sadee W

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Genome-scale metabolic models (GSMM) integrating transcriptomics have been widely used to study cancer metabolism. This integration is achieved through logical rules that describe the association between genes, proteins, and reactions (GPRs). However, current gene-to-reaction formulation lacks the stoichiome...

journal_title：BMC genomics

authors： Marín de Mas I,Torrents L,Bedia C,Nielsen LK,Cascante M,Tauler R

更新日期：2019-08-15 00:00:00

abstract：BACKGROUND:Segmental duplications (SDs) are not evenly distributed along chromosomes. The reasons for this biased susceptibility to SD insertion are poorly understood. Accumulation of SDs is associated with increased genomic instability, which can lead to structural variants and genomic disorders such as the Williams-B...

journal_title：BMC genomics

authors： Ebert G,Steininger A,Weißmann R,Boldt V,Lind-Thomsen A,Grune J,Badelt S,Heßler M,Peiser M,Hitzler M,Jensen LR,Müller I,Hu H,Arndt PF,Kuss AW,Tebel K,Ullmann R

更新日期：2014-06-29 00:00:00

abstract：BACKGROUND:After polyploidization, a genome may experience large-scale genome-repatterning, featuring wide-spread DNA rearrangement and loss, and often chromosome number reduction. Grasses share a common tetraploidization, after which the originally doubled chromosome numbers reduced to different chromosome numbers amo...

journal_title：BMC genomics

authors： Wang Z,Wang J,Pan Y,Lei T,Ge W,Wang L,Zhang L,Li Y,Zhao K,Liu T,Song X,Zhang J,Yu J,Hu J,Wang X

更新日期：2019-03-07 00:00:00

abstract：BACKGROUND:Environmental heterogeneity continuously produces a selective pressure that results in genomic variation among organisms; understanding this relationship remains a challenge in evolutionary biology. Here, we evaluated the degree of genome-environmental association of seven stonefly species across a wide geog...

journal_title：BMC genomics

authors： Gamboa M,Watanabe K

更新日期：2019-01-24 00:00:00

abstract：BACKGROUND:Matricaria recutita (German chamomile) and Chamaemelum nobile (Roman chamomile) belong to the botanical family Asteraceae. These two herbs are not only morphologically distinguishable, but their secondary metabolites - especially the essential oils present in flowers are also different, especially the terpen...

journal_title：BMC genomics

authors： Tai Y,Hou X,Liu C,Sun J,Guo C,Su L,Jiang W,Ling C,Wang C,Wang H,Pan G,Si X,Yuan Y

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:gammadelta T cells differ from alphabeta T cells with regard to the types of antigen with which their T cell receptors interact; gammadelta T cell antigens are not necessarily peptides nor are they presented on MHC. Cattle are considered a "gammadelta T cell high" species indicating they have an increased pr...

journal_title：BMC genomics

authors： Herzig CT,Lefranc MP,Baldwin CL

更新日期：2010-02-09 00:00:00

abstract：BACKGROUND:Genomic selection based on genotyping-by-sequencing (GBS) data could accelerate alfalfa yield gains, if it displayed moderate ability to predict parent breeding values. Its interest would be enhanced by predicting ability also for germplasm/reference populations other than those for which it was defined. Pre...

journal_title：BMC genomics

authors： Annicchiarico P,Nazzicari N,Li X,Wei Y,Pecetti L,Brummer EC

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Mitochondrial genomes comprise a small but critical component of the total DNA in eukaryotic organisms. They encode several key proteins for the cell's major energy producing apparatus, the mitochondrial respiratory chain. Additionally, their nucleotide and amino acid sequences are of great utility as marker...

journal_title：BMC genomics

authors： Lloyd RE,Foster PG,Guille M,Littlewood DT

更新日期：2012-09-19 00:00:00