Clinical and radiological aspects of dysplastic gangliocytoma (Lhermitte-Duclos disease): a report of two cases with review of the literature.

Abstract:

:Two cases of Lhermitte-Duclos disease confirmed by biopsy are reported. Review of the 58 published cases shows that the disease can manifest itself only by signs of increased intracranial pressure. Cerebellar symptoms are not constant. Computed tomographic (CT) scans suggest the diagnosis by showing a posterior fossa lesion, iso- and hypodense, partially calcified, and not enhanced by contrast medium. Magnetic resonance imaging (MRI) seems to define limits of the lesion better than CT scanning and could improve the surgical approach. Surgical excision of the lesion is the only satisfactory treatment. The postoperative prognosis is usually favorable.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Milbouw G,Born JD,Martin D,Collignon J,Hans P,Reznik M,Bonnal J

doi

10.1227/00006123-198801010-00020

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

124-8

issue

1 Pt 1

eissn

0148-396X

issn

1524-4040

journal_volume

22

pub_type

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