Abstract:
:As a mental framework for the transition of self-replicating biological forms, the RNA world concept stipulates a dual function of RNAs as genetic substance and catalyst. The chaperoning function is found intrinsic to ribozymes involved in protein synthesis and tRNA maturation, enriching the primordial RNA world with proteins of biological relevance. The ribozyme-resident protein folding activity, even before the advent of protein-based molecular chaperone, must have expedited the transition of the RNA world into the present protein theatre.
journal_name
RNA Bioljournal_title
RNA biologyauthors
Son A,Horowitz S,Seong BLdoi
10.1080/15476286.2020.1801199subject
Has Abstractpub_date
2021-01-01 00:00:00pages
16-23issue
1eissn
1547-6286issn
1555-8584journal_volume
18pub_type
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