Abstract：
:Apis cerana honey collected from the Qinling Mountains in China has been widely used for its antimicrobial property in traditional Chinese medicine. However, its antibacterial mechanism against Salmonella Typhimurium LT2 is still uncertain. A total of 52 volatile components were identified using headspace-gas-chromatography-ion-mobility, and Qinling A. cerana honey exhibited more abundant aromas than monofloral honeys. The phenolic extracts of honey sample F exhibited the lowest minimum inhibitory concentration (5 mg/mL), and chlorogenic acid exhibited the highest (155.91 ± 0.79 mg/kg), followed by caffeic acid, and rutin. After being treated with the extract, cell membranes of S. Typhimurium LT2 significantly shrunk and further collapsed. The extract treatment on mice caused a significant decrease in S. Typhimurium LT2, and a dramatic increase in the potential prebiotic Lactobacillus in both the caecum and colon. The results demonstrate that the Qinling A. cerana honey extract could effectively inhibit S. Typhimurium in vitro and in vivo.
journal_name
Food Chemjournal_title
Food chemistryauthors
Wang Y,Gou X,Yue T,Ren R,Zhao H,He L,Liu C,Cao Wdoi
10.1016/j.foodchem.2020.127774subject
Has Abstractpub_date
2021-02-01 00:00:00pages
127774eissn
0308-8146issn
1873-7072pii
S0308-8146(20)31636-8journal_volume
337pub_type
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