NOTCH2 participates in Jagged1-induced osteogenic differentiation in human periodontal ligament cells.

abstract：:Pulmonary fibrosis is a serious lung disorder that can lead to respiratory failure. Here we show that transgenic mice expressing active renin from the liver (RenTgMK) developed progressive pulmonary fibrosis leading to impaired pulmonary function. Histological analyses revealed a marked increase in extracellular matri...

journal_title：Scientific reports

authors： Wang J,Chen L,Chen B,Meliton A,Liu SQ,Shi Y,Liu T,Deb DK,Solway J,Li YC

更新日期：2015-10-23 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Ravanbakhsh H,Bao G,Mongeau L

更新日期：2020-03-24 00:00:00

abstract：:The exposure of humans to erionite fibres of appropriate morphology and dimension has been unambiguously linked to the occurrence of Malignant Mesothelioma. For this reason, a detailed morpho-structural investigation through Electron Microscopy techniques has been performed on erionite samples collected at two differe...

journal_title：Scientific reports

authors： Matassa R,Familiari G,Relucenti M,Battaglione E,Downing C,Pacella A,Cametti G,Ballirano P

更新日期：2015-11-16 00:00:00

abstract：:Optogenetic tools have opened a rich experimental landscape for understanding neural function and disease. Here, we present the first validation of eight optogenetic constructs driven by recombinant adeno-associated virus (AAV) vectors and a WGA-Cre based dual injection strategy for projection targeting in a widely-us...

journal_title：Scientific reports

authors： O'Shea DJ,Kalanithi P,Ferenczi EA,Hsueh B,Chandrasekaran C,Goo W,Diester I,Ramakrishnan C,Kaufman MT,Ryu SI,Yeom KW,Deisseroth K,Shenoy KV

更新日期：2018-04-30 00:00:00

abstract：:We report a new family with autosomal dominant inheritance of a late onset rapidly progressive leukodystrophy in which exome sequencing has revealed a novel mutation p.R782G in the Colony-Stimulating Factor 1 Receptor gene (CSF1R). Neuropathology of two affected family members showed cerebral white matter degeneration...

journal_title：Scientific reports

authors： Foulds N,Pengelly RJ,Hammans SR,Nicoll JA,Ellison DW,Ditchfield A,Beck S,Ennis S

更新日期：2015-05-15 00:00:00

abstract：:The alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) is known to trigger the adaptive response by inducing the ada-regulon - consisting of three DNA repair enzymes Ada, AlkB, AlkA and the enigmatic AidB. We have applied custom designed tiling arrays to study transcriptional changes in Escherichia coli foll...

journal_title：Scientific reports

authors： Booth JA,Thomassen GO,Rowe AD,Weel-Sneve R,Lagesen K,Kristiansen KI,Bjørås M,Rognes T,Lindvall JM

更新日期：2013-10-25 00:00:00

abstract：:Many experiments on human cooperation have revealed that individuals differ systematically in their tendency to cooperate with others. It has also been shown that individuals condition their behaviour on the overall cooperation level of their peers. Yet, little is known about how individuals respond to heterogeneity i...

journal_title：Scientific reports

authors： van den Berg P,Molleman L,Junikka J,Puurtinen M,Weissing FJ

更新日期：2015-11-04 00:00:00

abstract：:The cumulative effects of hepatic injury due to hepatitis B virus (HBV) infections and aflatoxin-B1 (AFB1) exposure are the major risk factors of HCC. Understanding early metabolic changes involving these risk factors in an animal model closely resembling human hepatocellular carcinoma (HCC) is critical for biomarker ...

journal_title：Scientific reports

authors： Yaligar J,Teoh WW,Othman R,Verma SK,Phang BH,Lee SS,Wang WW,Toh HC,Gopalan V,Sabapathy K,Velan SS

更新日期：2016-02-02 00:00:00

abstract：:Although the perception of faces depends on low-level neuronal processes, it is also affected by high-level social processes. Faces from a social in-group, such as people of a similar age, receive more in-depth processing and are processed holistically. To explore whether own-age biases affect subconscious face percep...

journal_title：Scientific reports

authors： Nicholls MER,Churches O,Loetscher T

更新日期：2018-08-23 00:00:00

abstract：:We discover and characterise strong quantum scars, or quantum eigenstates resembling classical periodic orbits, in two-dimensional quantum wells perturbed by local impurities. These scars are not explained by ordinary scar theory, which would require the existence of short, moderately unstable periodic orbits in the p...

journal_title：Scientific reports

authors： Luukko PJ,Drury B,Klales A,Kaplan L,Heller EJ,Räsänen E

更新日期：2016-11-28 00:00:00

abstract：:A generalization of the Raman scattering (RS) spectrum, the Raman excitation map (REM) is a hyperspectral two-dimensional (2D) data set encoding vibrational spectra, electronic spectra and their coupling. Despite the great potential of REM for optical sensing and characterization with remarkable sensitivity and select...

journal_title：Scientific reports

authors： Finnie P,Ouyang J,Lefebvre J

更新日期：2020-06-08 00:00:00

abstract：:Ecological adaptations to seasonal changes are often observed in the phenotypic traits of plants and animals, and these adaptations are usually expressed through the production of different biochemical end products. In this study, ecological adaptations are observed in a biochemical pathway without alteration of the e...

journal_title：Scientific reports

authors： Hirata H,Ohnishi T,Tomida K,Ishida H,Kanda M,Sakai M,Yoshimura J,Suzuki H,Ishikawa T,Dohra H,Watanabe N

更新日期：2016-02-01 00:00:00

abstract：:Support from human genetics increases the probability of success in drug development. However, few examples exist of successful genomically-driven drug repositioning. Given that a Mendelian form of severe enterocolitis is due to up-regulation of the interleukin-18 (IL18) signaling pathway, and pharmacologic inhibition...

journal_title：Scientific reports

authors： Mokry LE,Zhou S,Guo C,Scott RA,Devey L,Langenberg C,Wareham N,Waterworth D,Cardon L,Sanseau P,Davey Smith G,Richards JB

更新日期：2019-06-28 00:00:00

abstract：:We aim to evaluate the association of systolic and diastolic blood pressure (SBP and DBP) with estimated urinary sodium (Na) and potassium(K) excretions, and their gram-to-gram Na/K ratio across various salt-diet regions during 2005-2009 in China. A prospective cohort study was conducted to recruit 46,285 participants...

journal_title：Scientific reports

authors： Yin L,Deng G,Mente A,Sun Y,Liu X,Zhang X,Wang X,Wang Y,Bo J,Chen H,Liu X,Gao N,Bai X,Rangarajan S,Li W

更新日期：2018-04-30 00:00:00

abstract：:Recently, the discovery of room temperature magnetoelectricity in organic charge transfer complexes has reignited interest in the multiferroic field. The solution processed, large-area and low cost organic semiconductor materials offer new possibilities for the functional all organic multiferroic devices. Here we repo...

journal_title：Scientific reports

authors： Han S,Yang L,Gao K,Xie S,Qin W,Ren S

更新日期：2016-06-23 00:00:00

abstract：:Adolescence is a critical stage of development and has an important influence on energy balance-related behaviours (EBRBs). When adolescents are associated with obesity it can lead to increased cardiometabolic risk. Here we assess if EBRBs adopted by adolescents included in a subsample are associated with markers of t...

journal_title：Scientific reports

authors： Forkert ECO,Moraes ACF,Carvalho HB,Manios Y,Widhalm K,González-Gross M,Gutierrez A,Kafatos A,Censi L,De Henauw S,Moreno LA

更新日期：2019-04-23 00:00:00

abstract：:Neutrophil gelatinase-associated lipocalin (NGAL) is involved in cardiovascular and renal diseases. Gene inactivation of NGAL blunts the pathophysiological consequences of cardiovascular and renal damage. We aimed to design chemical NGAL inhibitors and investigate its effects in experimental models of myocardial infar...

journal_title：Scientific reports

authors： Bonnard B,Martínez-Martínez E,Fernández-Celis A,Pieronne-Deperrois M,Do QT,Ramos I,Rossignol P,Zannad F,Mulder P,Ouvrard-Pascaud A,López-Andrés N,Jaisser F

更新日期：2021-01-28 00:00:00

abstract：:A connection between airway and gut microbiota related to allergen exposure in childhood allergies was not well addressed. We aimed to identify the microbiota alterations in the airway and gut related to mite-specific IgE responses in young children with airway allergies. This study enrolled 60 children, including 38 ...

journal_title：Scientific reports

authors： Chiu CY,Chan YL,Tsai MH,Wang CJ,Chiang MH,Chiu CC,Su SC

更新日期：2020-08-10 00:00:00

abstract：:Water-saving and drought-resistantce rice (WDR) breeding practices have greatly increased grain yield and drought resistance. To study the genetic basis of adaptation to drought, transcriptome sequences from the WDR maintainer line HuHan2B and the recurrent parent HanFengB were analyzed for alternative splicing (AS) c...

journal_title：Scientific reports

authors： Wei H,Lou Q,Xu K,Yan M,Xia H,Ma X,Yu X,Luo L

更新日期：2017-09-15 00:00:00

abstract：:Obesity, often represented by higher body mass index (BMI), is not yet fully understood as a potential risk factor for poor clinical outcomes of prostate cancer (PCa) after radical prostatectomy (RP). This study aimed to evaluate the relationship between BMI and biochemical recurrence (BCR)-free survival in RP patient...

journal_title：Scientific reports

authors： Yu YD,Byun SS,Lee SE,Hong SK

更新日期：2018-08-10 00:00:00

abstract：:Fatty acid oxidation and subsequent ketogenesis is one of the major mechanisms to maintain hepatic lipid homeostasis under fasting conditions. Fasting hormone glucagon has been shown to stimulate ketone body production through activation of PPARα; however, the signal pathway linking glucagon to PPARα is largely undisc...

journal_title：Scientific reports

authors： Zhang ZN,Gong L,Lv S,Li J,Tai X,Cao W,Peng B,Qu S,Li W,Zhang C,Luan B

更新日期：2016-03-17 00:00:00

abstract：:It well-known that mental training improves skill performance. Here, we evaluated skill acquisition and consolidation after physical or motor imagery practice, by means of an arm pointing task requiring speed-accuracy trade-off. In the main experiment, we showed a significant enhancement of skill after both practices ...

journal_title：Scientific reports

authors： Ruffino C,Truong C,Dupont W,Bouguila F,Michel C,Lebon F,Papaxanthis C

更新日期：2021-01-27 00:00:00

abstract：:Oxalate decarboxylase (OXDC) enzyme has immense biotechnological applications due to its ability to decompose anti-nutrient oxalic acid. Flammulina velutipes, an edible wood rotting fungus responds to oxalic acid by induction of OXDC to maintain steady levels of pH and oxalate anions outside the fungal hyphae. Here, w...

journal_title：Scientific reports

authors： Kamthan A,Kamthan M,Kumar A,Sharma P,Ansari S,Thakur SS,Chaudhuri A,Datta A

更新日期：2015-10-12 00:00:00

abstract：:Colors of crystals, pigments, metals, salt solutions and bioluminescence occur in nature due to the optical properties of electrons in atoms and molecules. However, colors can also result from interference effects on nanostructures. In contrast to artificial coloration, which are caused by well-defined regular structu...

journal_title：Scientific reports

authors： Zyla G,Kovalev A,Grafen M,Gurevich EL,Esen C,Ostendorf A,Gorb S

更新日期：2017-12-15 00:00:00

abstract：:Tin doped indium oxide (ITO) thin films provide excellent transparency and conductivity for electrodes in displays and photovoltaic systems. Current advances in producing printable ITO inks are reducing the volume of wasted indium during thin film patterning. However, their applicability to flexible electronics is hin...

journal_title：Scientific reports

authors： Serkov AA,Snelling HV,Heusing S,Amaral TM

更新日期：2019-02-11 00:00:00

abstract：:The crystal structure of the Sb6O13 oxide, exhibiting a defect pyrochlore crystal structure with atomic vacancies, has been studied using a complete set of state-of-the-art techniques. The degree of antimony disproportionation in Sb3+ and Sb5+ valence states has been directly determined around 36% and 64%, respectivel...

journal_title：Scientific reports

authors： Mayer SF,Rodrigues JE,Marini C,Fernández-Díaz MT,Falcón H,Asensio MC,Alonso JA

更新日期：2020-10-12 00:00:00

abstract：:Hollow fiber composite NF membranes with improved anti-fouling property and water flux were prepared via interfacial polymerizationand layer-by-layer method using polyethylenimine (PEI), isophthaloyl dichloride (IPC), and β-cyclodextrin (β-CD). The chemical structures and the morphologies of the resultant NF membranes...

journal_title：Scientific reports

authors： He Y,Miao J,Jiang Z,Tu K,Yang H,Chen S,Zhang L,Zhang R

更新日期：2019-08-27 00:00:00

abstract：:We study the time-development processes of spin and charge transport phenomena in a topological Dirac semimetal attached to a ferromagnetic insulator with a precessing magnetization. Compared to conventional normal metals, topological Dirac semimetals manifest a large inverse spin Hall effect when a spin current is pu...

journal_title：Scientific reports

authors： Misawa T,Nomura K

更新日期：2019-12-23 00:00:00

abstract：:Rice lines with slower starch digestibility provide opportunities in mitigating the global rise in type II diabetes and related non-communicable diseases. However, screening for low glycemic index (GI) in rice breeding programs is not possible due to time and cost constraints. This study evaluated the feasibility of u...

journal_title：Scientific reports

authors： Guzman MK,Parween S,Butardo VM,Alhambra CM,Anacleto R,Seiler C,Bird AR,Chow CP,Sreenivasulu N

更新日期：2017-07-19 00:00:00

abstract：:Cassava is an important staple crop in tropical and sub-tropical areas. As a common farming practice, cassava is usually cultivated intercropping with other crops and subjected to various degrees of shading, which causes reduced productivity. Herein, a comparative transcriptomic analysis was performed on a series of d...

journal_title：Scientific reports

authors： Ding Z,Zhang Y,Xiao Y,Liu F,Wang M,Zhu X,Liu P,Sun Q,Wang W,Peng M,Brutnell T,Li P

更新日期：2016-08-19 00:00:00