Abstract：
:The impacts of chitosan with different molecular weight on the formation mechanism, structural characteristics and encapsulating properties of the zein-chitosan nanocomplexes were investigated. The results of dynamic light scattering showed that the mean size of nanocomplexes was increased and became more highly positive charge as the molecular weight of chitosan was increased. Circular dichroism indicated that the secondary structure of zein changed after its combination of chitosan. XRD confirmed that quercetagetin was successfully encapsulated into the nanocomplexes, and FTIR revealed that hydrogen bonding and hydrophobic interaction were the main forces acting among the zein, quercetagetin, and chitosan molecules. The optimized zein-Que-LCH (low molecular weight chitosan) nanocomplexes were relatively small (309 nm), positively charged (+42.5 mV), and had a high entrapment efficiency (94.9%). Moreover, encapsulation of quercetagetin within the nanocomplexes extended its half-life by 3.84- and 2.98- folds during the photo- and thermal-degradation measurements, and effectively modulated its release under simulated gastrointestinal conditions.
journal_name
Int J Biol Macromoljournal_title
International journal of biological macromoleculesauthors
Chen S,Ma X,Han Y,Wei Y,Guo Q,Yang S,Zhang Y,Liao W,Gao Ydoi
10.1016/j.ijbiomac.2020.07.245subject
Has Abstractpub_date
2020-12-01 00:00:00pages
2215-2223eissn
0141-8130issn
1879-0003pii
S0141-8130(20)34008-3journal_volume
164pub_type
杂志文章abstract：:In this study, graphene oxide-chitosan (GO-CS) and graphene oxide-chitosan-ZnO (GO-CS-ZnO) hybrids were synthesized in order to examine the effectiveness of hybridization in enhancing the corrosion inhibition activity of graphene oxide (GO). In this way, the synthesized GO and nano-hybrids were firstly characterized b...
journal_title：International journal of biological macromolecules
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journal_title：International journal of biological macromolecules
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journal_title：International journal of biological macromolecules
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journal_title：International journal of biological macromolecules
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journal_title：International journal of biological macromolecules
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journal_title：International journal of biological macromolecules
pub_type： 杂志文章
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journal_title：International journal of biological macromolecules
pub_type： 杂志文章
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journal_title：International journal of biological macromolecules
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journal_title：International journal of biological macromolecules
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journal_title：International journal of biological macromolecules
pub_type： 杂志文章
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journal_title：International journal of biological macromolecules
pub_type： 杂志文章
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journal_title：International journal of biological macromolecules
pub_type： 杂志文章
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journal_title：International journal of biological macromolecules
pub_type： 杂志文章
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journal_title：International journal of biological macromolecules
pub_type： 杂志文章
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journal_title：International journal of biological macromolecules
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journal_title：International journal of biological macromolecules
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abstract：:Pseudomonas chlororaphis subsp. aurantiaca (DSM 19603) was grown on crude glycerol from biodiesel production to produce a medium-chain-length polyhydroxyalkanoate (mcl-PHA), composed of 3-hydroxydodecanoate (43 ± 1.8 mol%), 3-hydroxydecanoate (29 ± 3.1 mol%), 3-hydroxytetradecanoate (12 ± 0.4 mol%), 3-hydroxyoctanoate...
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abstract：:Artemisinin, a natural anti-malarial agent, also possesses anti-proliferative and anti-angiogenic activity in cancer cells with very low toxicity to normal healthy cells. Drug loaded magnetic nanoparticles by using external magnetic field could selectively accumulate the drug at the target site and thereby reduce the ...
journal_title：International journal of biological macromolecules
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journal_title：International journal of biological macromolecules
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