Abstract：
:Investigation of physician-related causes of unscheduled revisits to the emergency department (ED) within 72 h with subsequent admission to the intensive care unit (ICU) is an important parameter of emergency care quality. Between 2012 and 2017, medical records of all adult patients who visited the ED and returned within 72 h with subsequent ICU admission were retrospectively reviewed by three experienced emergency physicians. Study parameters were categorized into "input" (Patient characteristics), "throughput" (Time spent on first ED visit and seniority of emergency physicians, and "output" (Charlson Comorbidity Index). Of the 147 patients reviewed for the causes of ICU admission, 35 were physician-related (23.8%). Eight belonged to more urgent categories, whereas the majority (n = 27) were less urgent. Patients who spent less time on their first ED visits before discharge (< 2 h) were significantly associated with physician-related causes of ICU admission, whereas there was no significant difference in other "input," "throughput," and "output" parameters between the "physician-related" and "non-physician-related" groups. Short initial management time was associated with physician-related causes of ICU admission in patients with initial less urgent presentations, highlighting failure of the conventional triage system to identify potentially life-threatening conditions and possibility of misjudgement because of the patients' apparently minor initial presentations.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Chang CS,Lee KH,Su HY,Sun CK,Tsai IT,Lo YY,Hsu CWdoi
10.1038/s41598-020-70021-1subject
Has Abstractpub_date
2020-08-03 00:00:00pages
13060issue
1issn
2045-2322pii
10.1038/s41598-020-70021-1journal_volume
10pub_type
杂志文章abstract：:The potential of Massively Parallel Sequencing (MPS) technology to vastly expand the capabilities of human identification led to the emergence of different MPS platforms that use forensically relevant genetic markers. Two of the MPS platforms that are currently available are the MiSeq® FGx™ Forensic Genomics System (I...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00510-3
更新日期：2017-03-24 00:00:00
abstract：:IHC4 and PAM50 assays have been shown to provide additional prognostic information for patients with early breast cancer. We evaluated whether incorporating TP53 mutation analysis can further enhance their prognostic accuracy. We examined TP53 mutation and the IHC4 score in tumors of 605 patients diagnosed with stage ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17879
更新日期：2015-12-16 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-65968-0
更新日期：2020-06-04 00:00:00
abstract：:Invasive species are characterized by their ability to colonize new habitats and establish populations away from their native range. In this sense, these plants are expected to have plastic responses to adapt to the environmental pressures during the invasion process. Hence, the role of natural selection is essential ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76922-5
更新日期：2020-11-18 00:00:00
abstract：:Taste is a vital sensation for vertebrates, enabling the detection of nutritionally important substances or potential toxins. A heteromeric complex of two class C GPCRs, T1R1 and T1R3, was identified as the umami (savory) taste receptor. Amino acids and 5'-ribonucleotides are well known to be natural ligands for human...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30315-x
更新日期：2018-08-07 00:00:00
abstract：:The objective of this study is to investigate the performance of a serpentine channel for acoustically driven selective particle filtering. The channel consists of sharp corners and straight sections, and the acoustic field is affecting the particles throughout the channel. A prototype of the separator channel is manu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43711-8
更新日期：2019-05-09 00:00:00
abstract：:The early Pliocene shoaling of the Central American Seaway (CAS), ~4.7-4.2 million years ago (mega annum-Ma), is thought to have strengthened Atlantic Meridional Overturning Circulation (AMOC). The associated increase in northward flux of heat and moisture may have significantly influenced the evolution of Pliocene cl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12252
更新日期：2015-07-20 00:00:00
abstract：:Disseminated diseases of the central nervous system such as amyotrophic lateral sclerosis (ALS) require that therapeutic agents are delivered and distributed broadly. Intrathecal route is attractive in that respect, but to date there was no methodology available allowing for optimization of this technique to assure sa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34723-x
更新日期：2018-11-07 00:00:00
abstract：:Low Haemoglobin concentration (Hb) among women of reproductive age is a severe public health problem in sub-Saharan Africa. This study investigated the effects of putative socio-demographic factors on maternal Hb at different points of the conditional distribution of Hb concentration. We utilised quantile regression t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78617-3
更新日期：2020-12-07 00:00:00
abstract：:Compression of optical pulses to ultrashort pulse widths using methods of nonlinear optics is a well-established technology of modern laser science. Extending these methods to pulses with high peak powers, which become available due to the rapid progress of laser technologies, is, however, limited by the universal phy...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36263
更新日期：2017-04-03 00:00:00
abstract：:Thyroid hormone (TH) has long been believed to play a minor role in male reproduction. However, evidences from experimental model of thyrotoxicosis or hypothyroidism suggests its role in spermatogenesis. Cellular action of TH requires membrane transport via specific transporters such as monocarboxylate transporter 8 (...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67594-2
更新日期：2020-07-07 00:00:00
abstract：:Alternative tillage and rice establishment options should aim at less water and labor to produce similar or improved yields compared with traditional puddled-transplanted rice cultivation. The relative performance of these practices in terms of yield, water input, and economics varies across rice-growing regions. A gl...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析
doi：10.1038/s41598-017-09742-9
更新日期：2017-08-24 00:00:00
abstract：:We examined the physical and mechanical properties of wood in Siberian larch (Larix sibirica) trees that grow naturally in five Mongolian provenances (Khentii, Arkhangai, Zavkhan, Khuvsgul, and Selenge) and the geographic variations between them. Five trees with stem diameters of 20 to 30 cm at 1.3 m above ground were...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69781-7
更新日期：2020-07-31 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-24031-9
更新日期：2018-04-11 00:00:00
abstract：:Although TRAIL can directly induce cell death in some cancer cells, it appears that TRAIL resistance exists in many cancers. This study focuses on anti-cancer drugs for TRAIL-resistant head and neck cancer (HNC) to provide further progress toward effective cancer therapy. Results indicate in TRAIL-resistant HNC cells,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-31039-8
更新日期：2018-08-21 00:00:00
abstract：:Transcranial direct current stimulation (tDCS) is a useful noninvasive technique of cortical brain stimulation for the treatment of neurological disorders. Clinical research has demonstrated tDCS with anodal stimulation of primary motor cortex (M1) in Parkinson's disease (PD) patients significantly improved their moto...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12178
更新日期：2015-07-29 00:00:00
abstract：:For the first time, a design of a "deflecting elastic prism" is proposed and implemented for waves in a chiral medium. A novel model of an elastic lattice connected to a non-uniform system of gyroscopic spinners is designed to create a unidirectional wave pattern, which can be diverted by modifying the arrangement of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00054-6
更新日期：2017-01-31 00:00:00
abstract：:This study provides a pore-scale investigation of two-phase flow dynamics during primary drainage in a realistic heterogeneous rock sample. Using the lattice Boltzmann (LB) method, a series of three-dimensional (3D) immiscible displacement simulations are conducted and three typical flow patterns are identified and ma...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39741-x
更新日期：2019-03-04 00:00:00
abstract：:MicroRNAs (MiRNAs) have been found to be dysregulated in lung cancer tissues compared to their matched paracancerous tissues. However, the roles of miRNAs in peripheral blood as potential biomarkers for early diagnosis of lung cancer remain poorly understood. Here we found that miR-33a-5p and miR-128-3p were down-regu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35139-3
更新日期：2018-11-12 00:00:00
abstract：:The search for efficient chemotherapy drugs and other anti-cancer treatments would benefit from a deeper understanding of the tumor microenvironment (TME) and its role in tumor progression. Because in vivo experimental methods are unable to isolate or control individual factors of the TME and in vitro models often do ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59658-0
更新日期：2020-02-20 00:00:00
abstract：:The extensive redundancy in the use of invasion ligands by Plasmodium falciparum, and its unique ability to switch between invasion pathways have hampered vaccine development. P. falciparum strains Dd2 and W2mef have been shown to change from sialic acid (SA)-dependent to SA-independent phenotypes when selected on neu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24218-0
更新日期：2018-04-10 00:00:00
abstract：:A combination of techniques from 3D printing, tissue engineering and biomaterials has yielded a new class of engineered biological robots that could be reliably controlled via applied signals. These machines are powered by a muscle strip composed of differentiated skeletal myofibers in a matrix of natural proteins, in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03723-8
更新日期：2017-06-19 00:00:00
abstract：:Although it is known that malaria parasites proliferate in the midgut of mosquito vector, their detailed behaviors, from gamete maturation to formation of next generation sporozoite, have not been fully understood at cellular or molecular level. This is mainly attributed to technical difficulties of dissection and who...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38529-3
更新日期：2019-02-11 00:00:00
abstract：:Immune responses against gene therapy products limit its therapeutic efficacy and present a safety risk. Identification of agents that blunt immune reactions may aid in developing novel immunomodulatory therapies. Fingolimod (FTY720) is an FDA approved immunomodulatory drug for treating multiple sclerosis that inhibit...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-29355-0
更新日期：2018-07-19 00:00:00
abstract：:Accumulating evidence indicates the association between obesity and lung function. However, no previous study has examined whether obesity affects lung function in normal weight participants with high body fat. We hypothesized that subjects with normal weight obesity (NWO) were inversely associated with lung function ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38804-3
更新日期：2019-06-20 00:00:00
abstract：:We explored the potential relevance of aqueous lysophosphatidic acid (LPA) and autotaxin (ATX) levels on postoperative outcomes of trabeculectomy, and the effects of ATX on fibrotic response in cultured human conjunctiva fibroblast (HCF) cells. We enrolled 70 glaucomatous eyes which underwent trabeculectomy, and quant...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-29649-3
更新日期：2018-07-27 00:00:00
abstract：:The green bacterial biosynthesis of lead sulfide nanocrystallites by L-cysteine-desulfurizing bacterium Lysinibacillus sphaericus SH72 was demonstrated in this work. Nanocrystals formed by this bacterial method were characterized using the mineralogical and morphological approaches. The results revealed that the micro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80450-7
更新日期：2021-01-13 00:00:00
abstract：:Complex systems, arising in many contexts in the computer, life, social, and physical sciences, have not shared a generally-accepted complexity measure playing a fundamental role as the Shannon entropy H in statistical mechanics. Superficially-conflicting criteria of complexity measurement, i.e. complexity-randomness ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01585
更新日期：2013-01-01 00:00:00
abstract：:Next generation sequencing is transforming clinical medicine and genome research, providing a powerful route to establishing molecular diagnoses for genetic conditions; however, challenges remain given the volume and complexity of genetic variation. A number of methods integrate patient phenotype and genotypic data to...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13841-y
更新日期：2017-10-18 00:00:00
abstract：:It has been shown that bamboo leaf flavone (BLF) displays biological and pharmacological activities in mammals. However, the effects of BLF on broiler gut microbiota and related immune function have not been investigated. The aim of this study was to test our hypothesis that BLF can improve the health status of broile...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69010-1
更新日期：2020-07-23 00:00:00
