A pilot study of the preliminary efficacy of Pain Buddy: A novel intervention for the management of children's cancer-related pain.

abstract：:VPS45-associated severe congenital neutropenia (SCN) is a rare disorder characterized by life-threating infections, neutropenia, neutrophil and platelet dysfunction, poor response to filgrastim, and myelofibrosis with extramedullary hematopoiesis. We present a patient with SCN due to a homozygous c.1403C>T (p.P468L) m...

journal_title：Pediatric blood & cancer

authors： Shah RK,Munson M,Wierenga KJ,Pokala HR,Newburger PE,Crawford D

更新日期：2017-09-01 00:00:00

abstract：:Undifferentiated embryonal sarcoma of the liver (UESL) is a rare aggressive mesenchymal pediatric tumor. Previously, reported outcomes have been very poor. Here, we report a single-center experience of five patients with UESL treated with upfront gross total resection and adjuvant chemotherapy. We have a median follow...

journal_title：Pediatric blood & cancer

authors： Mathias MD,Ambati SR,Chou AJ,Slotkin EK,Wexler LH,Meyers PA,Magnan H

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:The prognostic impact of central nervous system (CNS) involvement in children with acute myeloid leukemia (AML) has varied in past trials, and controversy exists over the degree of involvement requiring intensified CNS therapy. Two recent Children's Oncology Group protocols, AAML03P1 and AAML0531, directed a...

journal_title：Pediatric blood & cancer

authors： Johnston DL,Alonzo TA,Gerbing RB,Aplenc R,Woods WG,Meshinchi S,Gamis AS

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The aim was to evaluate self-reported reproductive characteristics and markers of ovarian function in a nationwide cohort of female survivors of childhood acute lymphoblastic leukemia (ALL), because prior investigations have produced conflicting data. PROCEDURE:Self-reported reproductive characteristics wer...

journal_title：Pediatric blood & cancer

authors： Roshandel R,van Dijk M,Overbeek A,Kaspers G,Lambalk C,Beerendonk C,Bresters D,van der Heiden-van der Loo M,van den Heuvel-Eibrink M,Kremer L,Loonen J,van der Pal H,Ronckers C,Tissing W,Versluys B,van Leeuwen F,van den Ber

更新日期：2021-01-18 00:00:00

abstract：PURPOSE:Chemotherapy during radiation and/or bone-seeking radioisotope therapy (153-samarium; 1 mCi/kg) during radiation may improve osteosarcoma cancer control. PATIENTS AND METHODS:We analyzed our preliminary radiation experience in high-risk, metastatic, and/or recurrent patients during a consecutive period of 20 m...

journal_title：Pediatric blood & cancer

authors： Mahajan A,Woo SY,Kornguth DG,Hughes D,Huh W,Chang EL,Herzog CE,Pelloski CE,Anderson P

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Few data exist regarding the clinical outcome of patients with Ewing sarcoma (EWS) treated with pencil beam scanning proton therapy (PT). We report the outcome of children, adolescents and young adults (AYA) treated with PT at the Paul Scherrer Institute. MATERIALS:Thirty-eight patients (median age, 9.9 yea...

journal_title：Pediatric blood & cancer

authors： Weber DC,Murray FR,Correia D,Bolsi A,Frei-Welte M,Pica A,Lomax AJ,Schneider R,Bachtiary B

更新日期：2017-12-01 00:00:00

abstract：:As a sympathetic nervous system-derived tumor, aggressive neuroblastoma (NB) is currently attracting interest from researchers seeking diagnostic and prognostic markers via less invasive procedures. The analysis of circulating tumor DNA (ctDNA) in peripheral blood can provide genetic information from multiple tumor le...

journal_title：Pediatric blood & cancer

authors： Wei M,Ye M,Dong K,Dong R

更新日期：2020-10-01 00:00:00

abstract：:Severe congenital neutropenia (SCN) is a bone marrow failure disease with an autosomal dominant inheritance from mutations in ELANE. Here, we report a 7-week-old Korean male with SCN. His elder sister died from pneumonia at 2 years. Direct sequencing of ELANE in the proband identified a heterozygous novel frameshift m...

journal_title：Pediatric blood & cancer

authors： Kim HJ,Song MJ,Lee KO,Kim SH,Kim HJ

更新日期：2015-12-01 00:00:00

abstract：:Surgery plays an important role as part of the treatment plan in most children with malignant solid tumors in regards to initial biopsy, upfront resection, and delayed resection. Surgeons also play a critical role in the treatment of surgical complications that may arise during medical treatment. The pediatric surgica...

journal_title：Pediatric blood & cancer

authors： Fernandez-Pineda I,Sanders D,Rao BN,Shochat SJ,Davidoff AM

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Hematopoietic stem cell transplantation (HSCT) provides a curative therapy for children severely affected by sickle cell disease (SCD). Rejection-free survival after matched sibling donor (MSD) HSCT is very high, but adoption of HSCT as a curative SCD therapy has been slow. In this study, we assess providers...

journal_title：Pediatric blood & cancer

authors： Meier ER,Abraham AA,Ngwube A,Janson IA,Guilcher GMT,Horan J,Kasow KA

更新日期：2021-03-01 00:00:00

abstract：:Twenty-eight patients were maintained on subcutaneous immunoglobulin replacement for persistent B-cell aplasia and agammaglobulinemia following CD19-targeted chimeric antigen receptor T-cell therapy for B-cell lymphoblastic leukemia. Patients were transitioned from intravenous to subcutaneous immunoglobulin replacemen...

journal_title：Pediatric blood & cancer

authors： Arnold DE,Maude SL,Callahan CA,DiNofia AM,Grupp SA,Heimall JR

更新日期：2020-03-01 00:00:00

abstract：:Familial adenomatous polyposis (FAP) due to APC mutation is associated with an increased risk of hepatoblastoma. All cases of hepatoblastoma in patients with FAP reported in the literature were reviewed. One hundred and nine patients were identified. Thirty-five patients (of 49 with data) were diagnosed with hepatobla...

journal_title：Pediatric blood & cancer

authors： Trobaugh-Lotrario AD,López-Terrada D,Li P,Feusner JH

更新日期：2018-08-01 00:00:00

abstract：:MIRAGE syndrome caused by mutations in SAMD9 is associated with potential loss of chromosome 7 (-7/7q-) and an increased risk to develop myelodysplastic syndrome (MDS). We report a case of MIRAGE syndrome, caused by a novel SAMD9 mutation p.Leu641Pro, leading to characteristic clinical features as well as to the coexi...

journal_title：Pediatric blood & cancer

authors： Csillag B,Ilencikova D,Meissl M,Webersinke G,Laccone F,Narumi S,Haas O,Duba HC

更新日期：2019-04-01 00:00:00

abstract：:Time-to-antibiotic administration (TTA) has been suggested as a quality-of-care (QOC) measure for pediatric oncology patients with febrile neutropenia (FN). Unknown, however, is to what extent pediatric oncology centers utilize TTA. Therefore, we designed and administered an electronic survey (68% response rate) of pr...

journal_title：Pediatric blood & cancer

authors： McCavit TL,Winick N

更新日期：2012-02-01 00:00:00

abstract：:Adolescents and young adults (AYA) with acute lymphoblastic leukaemia (ALL) constitute a distinct population from children and older adults. Based on patterns of referral, they may be treated by either paediatric or adult oncologists. As a group, AYA with ALL have a worse survival and event-free survival (EFS) compare...

journal_title：Pediatric blood & cancer

authors： Ramanujachar R,Richards S,Hann I,Webb D

更新日期：2006-11-01 00:00:00

abstract：:Sickle cell disease (SCD) is an inherited red blood cell disorder that occurs worldwide and results in significant morbidity and mortality. In addition to affected children who are born in the US, an increasing number of children with SCD are migrating to the US with their families or through international adoption. C...

journal_title：Pediatric blood & cancer

authors： Thornburg CD,Ware RE

更新日期：2018-06-01 00:00:00

abstract：:Pneumocystis jiroveci pneumonia (PCP) is a serious complication in patients receiving chemotherapy or hematopoietic stem cell transplantation. Current recommendations for trimethoprim-sulfamethoxazole (TMP-SMZ) dosing as PCP prophylaxis in immunocompromised patients are based on either daily dosing or dosing three con...

journal_title：Pediatric blood & cancer

authors： Ohata Y,Ohta H,Hashii Y,Tokimasa S,Ozono K,Hara J

更新日期：2009-01-01 00:00:00

abstract：:Imatinib can be safely discontinued in adults with chronic myeloid leukemia (CML) where there is a prolonged complete molecular response (CMR). No data are available in the pediatric population. Six children with CML discontinued imatinib by themselves. Only three of them were in CMR but for <2 years. A significant in...

journal_title：Pediatric blood & cancer

authors： Millot F,Claviez A,Leverger G,Corbaciglu S,Groll AH,Suttorp M

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Histology after intensive induction chemotherapy is expected to become a beacon indicating when and how extensively radical surgery and lymph node dissection should be performed in advanced neuroblastoma. A thorough histologic review of surgical specimens was undertaken. PROCEDURE:All specimens from 34 pati...

journal_title：Pediatric blood & cancer

authors： Tsuchida Y,Miyauchi J,Kuroiwa M,Suzuki N,Sakamoto J,Suzuki M,Shitara T

更新日期：2005-10-15 00:00:00

abstract：BACKGROUND:We sought to determine the risk of bacteremia in a cohort of outpatient febrile nonneutropenic pediatric oncology patients and to assess clinical characteristics that may influence decisions regarding empiric antibiotic therapy. PROCEDURE:A single institution retrospective cohort study was performed of outp...

journal_title：Pediatric blood & cancer

authors： Kelly MJ,Vivier PM,Panken TM,Schwartz CL

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Despite the increasing cure rates for children with acute lymphoblastic leukemia (ALL), patients who relapse continue to have poor prognosis. The Children's Oncology Group (COG) conducted a limited institution Phase II trial of Campath-1H, a monoclonal antibody that targets CD52 on leukemic cells, in childre...

journal_title：Pediatric blood & cancer

authors： Angiolillo AL,Yu AL,Reaman G,Ingle AM,Secola R,Adamson PC

更新日期：2009-12-01 00:00:00

abstract：:Chronic granulomatous disease (CGD) is a primary immunodeficiency that affects the oxidative mechanism of microbial killing of phagocytic cells. The defect is characterized by a lack or severely reduced superoxide anion (O2-) production by phagocytes. Seventy percent of CGD cases are X-linked (X-CGD) and they are caus...

journal_title：Pediatric blood & cancer

authors： Barese CN,Copelli SB,De Matteo E,Zandomeni R,Salgueiro F,Di Giovanni D,Heyworth P,Rivas EM

更新日期：2005-04-01 00:00:00

abstract：:To search for novel mechanisms that contribute to the pathophysiology of idiopathic thrombocytopenic purpura (ITP), we determined the whole blood gene expression profile in five ITP patients and five control samples. Using DNA microarrays that contained 24,473 unique putative genes, we found 176 cDNAs that were strong...

journal_title：Pediatric blood & cancer

authors： Sood R,Wong W,Jeng M,Zehnder JL

更新日期：2006-10-15 00:00:00

abstract：BACKGROUND:Neuroblastoma is characterized by heterogeneity of histology, biology, and clinical behavior. Most epidemiology studies are based on Western and Japanese populations; there are very few studies on neuroblastoma from Southeast Asia. PROCEDURE:Cases of Thai children with neuroblastoma were retrospectively rev...

journal_title：Pediatric blood & cancer

authors： Shuangshoti S,Shuangshoti S,Nuchprayoon I,Kanjanapongkul S,Marrano P,Irwin MS,Thorner PS

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Childhood germ cell tumors (cGCTs), believed to arise from transformed primordial germ cells by an unknown mechanism, provide a unique model system for investigating cell signaling, pluripotency, and the microenvironment of neoplastic stem cells (NSCs) in vivo. This is the first report of proteomics of cGCTs...

journal_title：Pediatric blood & cancer

authors： Haskins WE,Eedala S,Jadhav YL,Labhan MS,Pericherla VC,Perlman EJ

更新日期：2012-05-01 00:00:00

abstract：:Juvenile myelomonocytic leukemia (JMML) has a poor prognosis in general, with hematopoietic stem cell transplant (HSCT) remaining the standard of care for cure. The hypomethylating agent, azacitidine, has been used as a bridging therapy to transplant. However, no patients have been treated with azacitidine without an ...

journal_title：Pediatric blood & cancer

authors： Hashmi SK,Punia JN,Marcogliese AN,Gaikwad AS,Fisher KE,Roy A,Rao P,Lopez-Terrada DH,Ringrose J,Loh ML,Niemeyer CM,Rau RE

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:To evaluate the association of central nervous system (CNS) treatment intensity and the social functioning of children who have completed treatment for leukemia, lymphoma, and solid tumors outside the CNS. Furthermore, we expected that these associations would be moderated by child age at diagnosis and gender. ...

journal_title：Pediatric blood & cancer

authors： Vannatta K,Gerhardt CA,Wells RJ,Noll RB

更新日期：2007-10-15 00:00:00

abstract：:We report two cases of primary CNS lymphoma (PCNSL) treated with high-dose methotrexate. Though standard adult treatment of PCNSL incorporates whole-brain radiotherapy, the literature suggests it may be possible to delay or avoid radiotherapy and the associated increased risk of neurologic sequelae in pediatric patien...

journal_title：Pediatric blood & cancer

authors： Shah AC,Kelly DR,Nabors LB,Oakes WJ,Hilliard LM,Reddy AT

更新日期：2010-12-01 00:00:00

abstract：:In Wilms tumor (WT), mutations in the gene encoding p53, TP53, are correlated with anaplasia; however TP53 variants have not been studied in favorable histology (FH) WTs. A single nucleotide polymorphism of TP53 encoding either arginine or proline at codon 72 is suggested to alter in vitro p53 behavior. Therefore, we ...

journal_title：Pediatric blood & cancer

authors： Cost NG,Mitui M,Khokhar S,Wickiser JE,Baker LA,Rakheja D

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Testicular germ cell tumors (T-GCTs) occur from infancy to adulthood, and are the most common solid tumor in adolescent and young adult males. Traditionally, pediatric T-GCTs were perceived as more indolent than adult T-GCTs. However, there are few studies comparing these groups and none that specifically ev...

journal_title：Pediatric blood & cancer

authors： Cost NG,Lubahn JD,Adibi M,Romman A,Wickiser JE,Raj GV,Sagalowsky AI,Margulis V

更新日期：2014-03-01 00:00:00