Biomarker study of the biological parameter and neurotransmitter levels in autistics.

abstract：:Recent studies have shown that adult osteoporosis could be induced by ageing and estrogen deficiency and homocysteine (Hcy) is an independent risk factor of fracture in osteoporosis patients. In this study, we found hypermethylation of the promoter A region in the estrogen receptor alpha (ERα) gene, and methylation in...

journal_title：Molecular and cellular biochemistry

authors： Lv H,Ma X,Che T,Chen Y

更新日期：2011-09-01 00:00:00

abstract：:Immunoassays such as rocket immunoelectrophoresis, western dot blot hybridization, and competitive ELISA analysis were used to estimate and compare homology among fishes (several species), crab, toad, chicken and rodent metallothioneins. The relative abundance of tissue-specific metallothionein in catfish was highest ...

journal_title：Molecular and cellular biochemistry

authors： Chatterjee A,Maiti IB

更新日期：1990-05-10 00:00:00

abstract：:TGR(mREN2)27 is a transgenic rat harboring the murine Ren-2 gene and exhibit fulminant hypertension and marked heart hypertrophy. In order to study the role of angiotensin II in the increase of cardiac mass, these animals were treated with antihypertensive and non-antihypertensive doses of the angiotensin II receptor ...

journal_title：Molecular and cellular biochemistry

authors： Böhm M,Lippoldt A,Wienen W,Ganten D,Bader M

更新日期：1996-10-01 00:00:00

abstract：:To define metabolic influences on cardiac myosin expression and sarcoplasmic reticulum (SR) Ca(2+)-stimulated ATPase streptozotocin-diabetic rats were treated for 9-10 wk with etomoxir, an inhibitor of carnitine palmitoyl transferase I (CPT-1) and fatty acid synthesis, or an antilipolytic drug, acipimox. Etomoxir redu...

journal_title：Molecular and cellular biochemistry

authors： Rupp H,Elimban V,Dhalla NS

更新日期：1994-03-16 00:00:00

abstract：:We report the isolation of a full length cDNA from cardiac muscle that encodes a approximately 73 kDa calcium/calmodulin (CaM) dependent kinase IIbeta isoform (CaMKIIbeta(C)) that was generated by alternative splicing of the CaMKIIbeta gene. Antipeptide antibodies raised to specific regions of the kinase identified a ...

journal_title：Molecular and cellular biochemistry

authors： Singh P,Leddy JJ,Chatzis GJ,Salih M,Tuana BS

更新日期：2005-02-01 00:00:00

abstract：:Ionizing radiation (IR) treatment results in activation of several DNA damage response molecules, such as ataxia telangiectasia, mutated (ATM), and DNA-dependent protein kinase (DNAPK) in mammals that are increasingly recognized for their potential roles in the sensing of DNA damage and initiating the subsequent prote...

journal_title：Molecular and cellular biochemistry

authors： Dhariwala FA,Narang H,Krishna M

更新日期：2012-04-01 00:00:00

abstract：:Lysosomes are defined traditionally with the marker enzyme acid phosphatase. We showed recently that lysosomes from human fibroblasts can be separated into a light and dense fraction as well as prelysosomal population. We now provide evidence that although acid phosphatase is enriched in all three fractions, the marke...

journal_title：Molecular and cellular biochemistry

authors： Kelly BM,Waheed A,Van Etten R,Chang PL

更新日期：1989-06-01 00:00:00

abstract：:Nocturnin has been identified as a clock-controlled gene based on its rhythmic expression and night-time peak of transcript level in Xenopus retina. Further studies show that the widespread expression and rhythmicity of nocturnin mRNA level parallel the expression of clock genes. In Xenopus, nocturnin transcription is...

journal_title：Molecular and cellular biochemistry

authors： Li R,Yue J,Zhang Y,Zhou L,Hao W,Yuan J,Qiang B,Ding JM,Peng X,Cao JM

更新日期：2008-10-01 00:00:00

abstract：:Primary cultures of skeletal muscle cells secrete plasminogen activator (PA) activity to the conditioning medium and display membrane-bound PA. Growth of these cells in culture in presence of 10(-7) M dexamethasone resulted in a marked reduction of the membranal and secreted PA activity. The hormone also reduced cytos...

journal_title：Molecular and cellular biochemistry

authors： Mayer M,Finci Z,Chaouat M,Sasson S

更新日期：1986-02-01 00:00:00

abstract：:In this study, we examined changes in the biochemical and inotropic events of the alpha(1)-adrenoceptor signaling pathway in hypothyroid rat hearts. Hypothyroidism was induced by treating experimental animals with 0.05% 6-n-propyl-2-thiouracil (PTU) in drinking water for 7 weeks. A significant decrease of beta- and an...

journal_title：Molecular and cellular biochemistry

authors： Jalali S,Durston M,Panagia V,Mesaeli N

更新日期：2006-02-01 00:00:00

abstract：:Fish and fish oils contain the omega-3 fatty acids known as eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA). Epidemiological studies have shown an inverse relation between the dietary consumption of fish containing EPA/DHA and mortality from coronary heart disease. These relationships have been substantiat...

journal_title：Molecular and cellular biochemistry

authors： Holub DJ,Holub BJ

更新日期：2004-08-01 00:00:00

abstract：:Recent reports considered that it was the disturbance of calcium homeostasis and the accumulation of misfolded proteins in the endoplasmic reticulum (ER) that activated hepatic stellate cells (HSCs) apoptosis and promoted fibrosis resolution. However, the signal-transducing events that are activated by ER stress after...

journal_title：Molecular and cellular biochemistry

authors： Huang Y,Li X,Wang Y,Wang H,Huang C,Li J

更新日期：2014-09-01 00:00:00

abstract：:Lithostathine may play a physiological role in preventing the precipitation of excess calcium in the pancreatic juice. The hypothesis has been advanced that in chronic calcifying pancreatitis the abnormal biosynthesis of lithostathine might be the original defect to which genetic proneness to the disease may be ascrib...

journal_title：Molecular and cellular biochemistry

authors： Cavallini G,Bovo P,Bianchini E,Carsana A,Costanzo C,Merola M,Sgarbi D,Frulloni L,Di Francesco V,Libonati M,Palmieri M

更新日期：1998-08-01 00:00:00

abstract：:Cigarette smoking is associated with a number of fatal diseases, including cancer of different organs. A number of oxoaldehydes are found in cigarette smoke, among which methylglyoxal (MG) is known to cause toxicity to cells upon accumulation. In biological systems, MG is converted to s-d-lactoylglutathione by glyoxal...

journal_title：Molecular and cellular biochemistry

authors： Biswas S,Gairola CG,Das SK

更新日期：2002-01-01 00:00:00

abstract：:Curcumin (Cur) is widely used as an anti-inflammation agent and has anti-depression potential. Neuroinflammation mediated by Ca2+ channel activation is closely associated with the progression of post-stroke depression (PSD). In the current study, the role of P2X7 receptor (P2X7R) in the anti-PSD function of Cur was ex...

journal_title：Molecular and cellular biochemistry

authors： Wang Z,Ren W,Zhao F,Han Y,Liu C,Jia K

更新日期：2020-02-01 00:00:00

abstract：:Many studies have explored whether the Notch signaling pathway has a tumor-suppressive or an oncogenic role in various tumors; however, the role of the Notch signaling pathway in salivary adenoid cystic carcinoma (SACC) is still unknown. In this study, we attempt to define the role of Notch2 signaling in cell growth, ...

journal_title：Molecular and cellular biochemistry

authors： Qu J,Song M,Xie J,Huang XY,Hu XM,Gan RH,Zhao Y,Lin LS,Chen J,Lin X,Zheng DL,Lu YG

更新日期：2016-01-01 00:00:00

abstract：:Ischemia/reperfusion injury causes cardiomyocyte apoptosis, ventricular remodeling, leading to a dilated heart. Hypoxia is one of the causes involved in ischemia damage, and BNIP3 is a hypoxia-inducible marker and also a sensor to induce mitochondria-dependent apoptosis. Recent reports discussed ablating BNIP3 can res...

journal_title：Molecular and cellular biochemistry

authors： Weng YJ,Kuo WW,Kuo CH,Tung KC,Tsai CH,Lin JA,Tsai FJ,Hsieh DJ,Huang CY,Hwang JM

更新日期：2010-12-01 00:00:00

abstract：:In view of the accumulation of H2O2 in the myocardium due to ischemia-reperfusion and changes in beta-adrenoceptor mechanisms in the ischemic-reperfused heart, we investigated the effects of H2O2 on the beta-adrenoceptor, G-protein and adenylyl cyclase complex. Rat hearts were perfused with 1 mM H2O2 for 10 min before...

journal_title：Molecular and cellular biochemistry

authors： Persad S,Panagia V,Dhalla NS

更新日期：1998-09-01 00:00:00

abstract：:Atherosclerotic lesions occur as a result of excess lipid deposition within the vascular tissues. The peroxisome proliferator-activated receptors (PPARs) present in adipose and hepatic tissues have been shown to promote fatty acid oxidation and lipid storage. An immunohistochemical assessment of PPARalpha and PPARgamm...

journal_title：Molecular and cellular biochemistry

authors： Zahradka P,Yurkova N,Litchie B,Moon MC,Del Rizzo DF,Taylor CG

更新日期：2003-04-01 00:00:00

abstract：:Changes in demands for Na+ transport alter expression of the Na+,K+ -ATPase subunit isoforms. In skeletal muscle, the effects of these changes on expression the alpha2 isoform, the major isoform expressed in differentiated muscle cell, is not known. Therefore, this study examines regulation of the alpha-subunit isofor...

journal_title：Molecular and cellular biochemistry

authors： Ladka R,Ng YC

更新日期：2000-08-01 00:00:00

abstract：:In the present study we investigated if administration of vitamin A could protect rat liver microsomes and mitochondria from in vitro peroxidation. Appreciable decrease of chemiluminescence and lipid peroxidation was measured in microsomal membranes from rats receiving vitamin A, with respect to control animals. In me...

journal_title：Molecular and cellular biochemistry

authors： Palacios A,Piergiacomi VA,Catalá A

更新日期：1996-01-12 00:00:00

abstract：:To investigate whether the action potential duration (APD) or resting tension was dependent on global ATP content, and whether they were preferentially dependent on glycolytic ATP, APD and resting tension were measured under various metabolic inhibition with corresponding measurement of ATP content in guinea pig ventr...

journal_title：Molecular and cellular biochemistry

authors： Hayashi H,Terada H,McDonald TF

更新日期：1999-04-01 00:00:00

abstract：:Pancreatic islet cytosol contains a calcium-calmodulin dependent protein kinase that can mediate the phosphorylation of an endogenous protein that has an Mr of 57 000, as well as exogenous muscle pyruvate kinase (subunit Mr, 57 000). EGTA and trifluoperazine decreased the phosphorylation. Alkaline inactivation of pyru...

journal_title：Molecular and cellular biochemistry

authors： MacDonald MJ,Kowluru A

更新日期：1985-10-01 00:00:00

abstract：:Five isoforms of CK2 may exist simultaneously in yeast cells: free catalytic subunits CK2α', CK2α and three holoenzymatic structures composed of αα'ββ', α(2)ββ' and α'(2)ββ'. Each isolated and purified form exhibits properties typical for CK2, but they differ in substrate specificity as well as in sensitivity to speci...

journal_title：Molecular and cellular biochemistry

authors： Janeczko M,Masłyk M,Szyszka R,Baier A

更新日期：2011-10-01 00:00:00

abstract：:Heat-shock protein90 (HSP90) plays an essential role in maintaining stability and activity of its clients. HSP90 is involved in cell differentiation and survival in a variety of cell types. To elucidate the possible role of HSP90 in myogenic differentiation and cell survival, we examined the time course of changes in ...

journal_title：Molecular and cellular biochemistry

authors： Wagatsuma A,Shiozuka M,Kotake N,Takayuki K,Yusuke H,Mabuchi K,Matsuda R,Yamada S

更新日期：2011-12-01 00:00:00

abstract：:Partially purified D-aspartate oxidase from beef kidney has been tested in the presence of butanedione or phenylglyoxal, which specifically modify the arginine molecule. The results obtained clearly indicate that arginine residues are involved in the binding of the substrate to the active site of the enzyme. ...

journal_title：Molecular and cellular biochemistry

authors： Crifò C,Santoro L,Rinaldi A,De Marco C

更新日期：1977-08-19 00:00:00

abstract：:Mitogen-activated protein kinase (MAPK) and renin-angiotensin system (RAS) play critical roles in the process of renal diseases, but their interaction has not been comprehensively discussed. In the present studies, we investigated the renoprotective effects of MPAK inhibitors on renal diseases in type 1 diabetic mouse...

journal_title：Molecular and cellular biochemistry

authors： Hong Z,Hong Z,Wu D,Nie H

更新日期：2016-08-01 00:00:00

abstract：:Circadian rhythms help organisms adapt to changes of external environment by regulating energy metabolism and remaining the balance of homeostasis. Numerous researches have proved that the physiological function of liver was precisely controlled by circadian rhythms. Clock, one of core circadian genes, has been demons...

journal_title：Molecular and cellular biochemistry

authors： Yang S,Liu Y,Guo Y,Liu R,Qi F,Li X,Yu H,Cheng S,Wang Z

更新日期：2020-04-01 00:00:00

abstract：:A systematic comparison of the impact of some potential endocrine disruptors (EDs) on modulation of androgen receptor (AR) and pregnane and xenobiotic receptor (PXR) function was conducted in a multi-step analysis. Promoter-reporter-based transcription assays were performed in conjunction with receptor dynamic studies...

journal_title：Molecular and cellular biochemistry

authors： Chaturvedi NK,Kumar S,Negi S,Tyagi RK

更新日期：2010-12-01 00:00:00

abstract：:Pluripotent stem cells within the adipose stromal compartment, termed adipose-derived stromal cells (ASCs), have the potential to differentiate into a variety of cell lineages both in vitro and in vivo. Imaging with expression of exogenous or endogenous green fluorescent protein (GFP) reporters facilitates the detaile...

journal_title：Molecular and cellular biochemistry

authors： Lin Y,Tian W,Chen X,Yan Z,Li Z,Qiao J,Liu L,Tang W,Zheng X

更新日期：2005-09-01 00:00:00