Abstract:
:Sarcopenia in patients with liver cirrhosis (LC) has been attracting much attention these days because of the close linkage to adverse outcomes. LC can be related to secondary sarcopenia due to protein metabolic disorders and energy metabolic disorders. LC is associated with profound alterations in gut microbiota and injuries at the different levels of defensive mechanisms of the intestinal barrier. Dysbiosis refers to a state in which the diversity of gut microbiota is decreased by decreasing the bacterial species and the number of bacteria that compose the gut microbiota. The severe disturbance of intestinal barrier in LC can result in dysbiosis, several bacterial infections, LC-related complications, and sarcopenia. Here in this review, we will summarize the current knowledge of the relationship between sarcopenia and dysbiosis in patients with LC.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Nishikawa H,Enomoto H,Nishiguchi S,Iijima Hdoi
10.3390/ijms21155254subject
Has Abstractpub_date
2020-07-24 00:00:00issue
15issn
1422-0067pii
ijms21155254journal_volume
21pub_type
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