In Vitro Closure Times (PFA-100) Are Different Between Peritoneal Dialysis and Hemodialysis.

abstract：:Platelets react immediately in response to traumatic vascular injury by adhesion, activation, aggregation and subsequent haemostatic plug formation. While this reaction pattern is essential for haemostasis, platelet responses can also cause occlusive thrombi in diseased arteries, leading to myocardial infarction or st...

journal_title：Hamostaseologie

authors： Scharf RE

更新日期：2018-11-01 00:00:00

abstract：UNLABELLED:A protein Z deficiency is presumably related with a threefold risk of venous and arterial thrombosis. Mucosal bleedings and post-operative haematomas can occur more frequently. This is seen in an increased in vivo bleeding time without other plasmatic coagulation disorders or thrombopathies. Pregnancy compli...

journal_title：Hamostaseologie

authors： Kiesewetter H,Radtke H,Jainz A,Schmidt FP

更新日期：2012-01-01 00:00:00

abstract：UNLABELLED:Clinical expression of inadequately treated haemophilia is dominated by orthopedic complications, requiring invasive or non-invasive interventions. OBJECTIVE:In Romania, with under dosed and late introduced "on demand" substitution, we aimed at highlighting the experience of orthopedic treatment and its out...

journal_title：Hamostaseologie

authors： Serban M,Mihailov MD,Poenaru D,Pop L,Branea I,Bataneant M,Lăcătuşu A,Barna L,Tepeneu N,Schramm W

更新日期：2008-10-01 00:00:00

abstract：:This article reviews the roles of blood platelets in haemostasis as well as in the pathogenesis of thromboembolic diseases. Besides the basic processes in primary haemostasis, platelet adhesion, platelet secretion, platelet aggregation, clot retraction, the new model of thrombin formation on the platelet surface is pr...

journal_title：Hamostaseologie

authors： Kehrel BE

更新日期：2008-12-01 00:00:00

abstract：:By the use of conventional anticoagulants, significant improvements were achieved in all fields of medicine. Although efficacious and widely used, their use is limited in several respects. In particular, the use of vitamin K antagonists is restricted in the clinical routine setting. The main reasons are the delayed on...

journal_title：Hamostaseologie

authors： Haas S

更新日期：2002-08-01 00:00:00

abstract：UNLABELLED:With the development of clotting-factors in the seventies the haemophilia patients were released from being handicapped and began to live a quite normal life. Thus, psychosocial counselling did not seem to be necessary. But the impact of HIV-infection to the world of haemophilia was so intense that professio...

journal_title：Hamostaseologie

authors： Schneider MM,Schramm W

更新日期：2010-11-01 00:00:00

abstract：UNLABELLED:Secondary arthrosis of the upper ankle joint (talocalcanean joint) is one of the most frequent forms of haemophilic arthropathy. It is a secondary form of arthrosis not only because of chronic synovitis and cartilage injury resulting from chronic recurrent intraarticular bleeds, but also due to the misalignm...

journal_title：Hamostaseologie

authors： Berdel P,Schott D,Pagenstert G,Pennekamp P,Oldenburg J,Wirtz DC,Seuser A,Gravius S

更新日期：2009-10-01 00:00:00

abstract：:Upon vascular injury or tissue damage, the exposed intracellular material such as nucleic acids, histones and other macromolecules may come into contact with vessel wall cells and circulating blood cells and may thus, have an enduring influence on wound healing and body defence processes. This short review summarizes ...

journal_title：Hamostaseologie

authors： Fischer S,Preissner KT

更新日期：2013-01-01 00:00:00

abstract：:Atherosclerosis and its sequelae have a major impact on morbidity and mortality. The rupture of an inflamed atherosclerotic plaque is a crucial event, since it can result in acute thrombotic closure of an arterial vessel, resulting e. g. in myocardial infarction or stroke. Not only detection of early plaque rupture wi...

journal_title：Hamostaseologie

authors： von Zur Muhlen C,Bode C

更新日期：2015-01-01 00:00:00

abstract：:Patients with diabetes are at increased risk of cardiovascular morbidity and mortality. While arteriosclerotic lesions have long been recognized as the underlying cause more recent studies suggest that alterations of the blood are also critically involved. Following plaque rupture, adherence of platelets is followed b...

journal_title：Hamostaseologie

authors： Hess K

更新日期：2015-01-01 00:00:00

abstract：:Cardiovascular and especially thrombotic diseases remain a major cause of morbidity and mortality worldwide. In past years, significant improvements in understanding disease processes, risk assessment, and prediction of clinical outcome in the field of thrombosis and haemostasis have been made by using large-scale bio...

journal_title：Hamostaseologie

authors： Panova-Noeva M,Eggebrecht L,Prochaska JH,Wild PS

更新日期：2019-06-01 00:00:00

abstract：:This case report concerns a pregnant multipara (age: 27 years) in the 16th gestational week. She developed a sudden onset of paraesthesia in her left lower arm although injecting dalteparin 5000 IU once daily subcutaneously (s. c.) due to a heterozygous factor V Leiden mutation and a prior miscarriage in the first pre...

journal_title：Hamostaseologie

authors： Hecking C,Hendelmeier M,von Bardeleben R,Gröschel K,Schinzel H

更新日期：2014-01-01 00:00:00

abstract：:For decades, the options for therapeutic anticoagulation were limited to unfractionated heparin (UFH) and vitamin K antagonists (VKA), and their well-known limitations had to be accepted. With the introduction of the various LMWHs, the short- and medium-term anticoagulation could be much improved, but an alternative t...

journal_title：Hamostaseologie

authors： Alban S

更新日期：2008-12-01 00:00:00

abstract：:Placenta-mediated pregnancy complications are clinically important conditions and include preeclampsia, placental abruption, intrauterine growth restriction, and late fetal loss. Pathophysiology is complex, and may be linked to prothrombotic disorders such as antiphospholipid syndrome, whose understanding is still evo...

journal_title：Hamostaseologie

authors： Skeith L,Blondon M,Ní Áinle F

更新日期：2020-08-01 00:00:00

abstract：:Atherosclerosis and its major complications - myocardial infarction and stroke - remain major causes of death and disability in the United States and world-wide. Indeed, with dramatic increases in obesity and diabetes mellitus, the prevalence and public health impact of cardiovascular diseases (CVD) will likely remain...

journal_title：Hamostaseologie

authors： Sun QA,Runge MS,Madamanchi NR

更新日期：2016-05-10 00:00:00

abstract：:The impact of inherited bleeding disorders on the socioeconomic status (SES) of affected individuals is not clear. The SES of adult patients with congenital bleeding disorders (PWBD) from a centre in Germany (age 42.3 ± 15.0 years) was compared to that of a gender- and age-matched control group of patients with thromb...

journal_title：Hamostaseologie

authors： Holstein K,von Mackensen S,Bokemeyer C,Langer F

更新日期：2018-08-01 00:00:00

abstract：:A survey is given on the clinical important haemostatic facts and diseases in gynaecology and obstetrics from the viewpoint of the gynecologist and obstetrician. ...

journal_title：Hamostaseologie

authors： Heilmann L

更新日期：2004-11-01 00:00:00

abstract：:The translation of fundamental science-based constructs to the preemptive identification and optimal management of individuals with or those at risk for thrombotic disorders of the cardiovascular system has taken a step closer to being realized with the development of molecular technologies that include nucleic acid a...

journal_title：Hamostaseologie

authors： Becker RC,Oney S,Becker KC,Rusconi CP,Sullenger B

更新日期：2007-12-01 00:00:00

abstract：:Superficial vein thrombosis (SVT) is a common disease, characterized by an inflammatory-thrombotic process in a superficial vein. Typical clinical findings are pain and a warm, tender, reddish cord along the vein. Until recently, no reliable epidemiological data were available. The incidence is estimated to be higher ...

journal_title：Hamostaseologie

authors： Bauersachs RM

更新日期：2013-08-01 00:00:00

abstract：:Current antithrombotic therapy in patients with acute coronary syndrome (ACS) comprises antiplatelet and anticoagulant therapy. Dual antiplatelet therapy composed of aspirin plus a third generation P2Y12 inhibitor (prasugrel or ticagrelor) represents the gold standard, while aspirin plus second generation P2Y12 inhibi...

journal_title：Hamostaseologie

authors： Ahrens I,Bode C,Zirlik A

更新日期：2014-01-01 00:00:00

abstract：:Vitamin K-antagonists and heparin belong to the established indirect acting anticoagulants. For many years these drugs were the only possibility for prophylaxis and treatment of venous and arterial thrombosis. The challenges for the routine laboratory related to the treatment with vitamin K-antagonists and heparin can...

journal_title：Hamostaseologie

authors： Schuster B

更新日期：2009-08-01 00:00:00

abstract：UNLABELLED:Antibodies against annexin-V, a potent anticoagulant abundant in placental tissues, were recently controversially reported to be associated with recurrent miscarriages or failures of in-vitro-fertilization (IVF) attempts. PATIENTS, MATERIAL, METHODS:We screened 56 women (34.7 +/- 4.3 years of age: mean +/- ...

journal_title：Hamostaseologie

authors： Halbmayer WM,Feichtinger W,Kindermann C,Prendinger B,Böhm M

更新日期：2005-11-01 00:00:00

abstract：UNLABELLED:An adequate number of qualified haemophilia centres is an essential requirement for effective and cost-efficient haemophilia care. During a reassessment of the delivery of haemophilia care in Germany a broad range of criteria relating to structure and quality of the centres were defined and a questionnaire w...

journal_title：Hamostaseologie

authors： Zimmermann R,Eifrig B,Lenk H,Pollmann H,Scharrer I,Huth-Kühne A

更新日期：2012-01-01 00:00:00

abstract：:The endothelium lining the vascular lumen is continuously exposed to complement from the circulation. When erroneously activated on host cells, complement may generate a deleterious effect on the vascular wall leading to endothelial injury, exposure of the subendothelial matrix and platelet activation. In this review ...

journal_title：Hamostaseologie

authors： Karpman D,Tati R

更新日期：2013-05-29 00:00:00

abstract：:Coronary heart disease and the acute coronary syndrome are the leading causes of death in Germany. In prospective observational studies conventional risk factors such as smoking, arterial hypertension, hypercholesterolaemia, and diabetes can explain over 80% of cardiovascular diseases. Therefore, cardiovascular diseas...

journal_title：Hamostaseologie

authors： Weingärtner O,Laufs U

更新日期：2006-05-01 00:00:00

abstract：:Replacement therapy of coagulation factor preparations (AT, FFP, PPSB, FXIII, rFVIIa) are frequently used on the Intensive Care Units. Indications, dosage, specific effects and side effects have to be considered. ...

journal_title：Hamostaseologie

authors： Scharrer I

更新日期：2005-05-01 00:00:00

abstract：:Direct oral anticoagulants (DOACs) are increasingly prescribed substances in patients with indication for effective anticoagulation. Patients with chronic kidney disease (CKD) have a high burden of cardiovascular risk and are more likely to develop atrial fibrillation (AF) than patients without CKD. Patients with mild...

journal_title：Hamostaseologie

authors： Kcükköylü S,Rump LC

更新日期：2017-01-01 00:00:00

abstract：:Thrombocytosis (defined as platelets >450 x 109/l) has several aetiologies. After having excluded spurious thrombocytosis (e. g., due to microspherocytes, schistocytes, cryoglobulins, or bacteria), the differential diagnosis of true thrombocytosis encompasses secondary causes (as diverse as inflammation, infection, ma...

journal_title：Hamostaseologie

authors： Alberio L

更新日期：2016-11-07 00:00:00

abstract：UNLABELLED:In recent years thrombophilia has gained much attention as a risk factor for pregnancy complications. Whereas there is an established correlation between antiphospholipid-antibodies and pregnancy loss, data for other risk factors of thrombosis are less well established. Data suggest associations with antithr...

journal_title：Hamostaseologie

authors： Pabinger I

更新日期：2008-01-01 00:00:00

abstract：:An understanding of reversal strategies alone is important to safely and effectively care for patients in cases of bleeding or invasive procedures. The recent diversification in the number of licensed anticoagulants makes an understanding of drug-specific reversal strategies essential. Intravenous or oral vitamin K ca...

journal_title：Hamostaseologie

authors： Koscielny J,Rutkauskaite E,Sucker C,von Heymann C

更新日期：2020-06-01 00:00:00