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Hypothalamic Hamartomas: A Comprehensive Review of Literature - Part 3: Updates on Radiotherapy Management.

Abstract：

:Hypothalamic hamartomas (HH) are rare, non-neoplastic heterotopic tissues which contains normal neurons and glia including oligodendrocytes and fibrillary astrocytes but in an abnormal distribution. They arise from the floor of the third ventricle, tuber cinereum, or mammillary bodies. Estimated incidence ranges from 1 in 50,000 to 1 in 1,000,000. Hypothalamic hamartomas are associated with different clinical presentations including various types of seizures, most characteristically; the gelastic seizures, precocious puberty, cognitive impairment and behavioral changes. In this review, the authors discuss the recent advancements in different modalities of radiotherapy and their application in hypothalamic hamartomas management.

journal_name

Clin Neurol Neurosurg

journal_title

Clinical neurology and neurosurgery

authors

Alomari SO,El Houshiemy MN,Bsat S,Moussalem CK,Allouh M,Omeis IA

doi

10.1016/j.clineuro.2020.106077

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

106077

eissn

0303-8467

issn

1872-6968

pii

S0303-8467(20)30420-0

journal_volume

197

pub_type

杂志文章,评审

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