Efficacy and safety of dual filtration plasmapheresis combined with biological agents in active refractory rheumatod arthritis: A retrospective cohort study.

abstract：:Gonadotropin induces masculinization and spermatogenesis in men with congenital hypogonadotropic hypogonadism (CHH). However, large cohort studies for the efficacy and reliable predictors of this therapy need to be conducted. The aim of this study was to investigate the efficacy of gonadotropin treatment in a large co...

journal_title：Medicine

authors： Liu Z,Mao J,Wu X,Xu H,Wang X,Huang B,Zheng J,Nie M,Zhang H

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Far-infrared irradiation (FIR) is used in the medical field to improve wound healing, hemodialysis with peripheral artery occlusive disease, and osteoarthritis but seldom used in ameliorating poor lower extremity circulation. The purpose of this study was to evaluate the effect of FIR on changes in foot skin...

journal_title：Medicine

authors： Peng TC,Chang SP,Chi LM,Lin LM

更新日期：2020-12-11 00:00:00

abstract：AIMS:Nicorandil, which is a mitochondrial ATP-sensitive potassium channel opener, is believed to improve perioperative myocardial injury (PMI) in patients undergoing percutaneous coronary intervention (PCI), but recent studies have shown that nicorandil treatment did not improve functional and clinical outcomes in pati...

journal_title：Medicine

authors： Zhu H,Xu X,Fang X,Zheng J,Chen T,Huang J

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Prognosis of intrahepatic cholangiocarcinoma (ICC) remained poor despite the multitude advancement of medical care. Resection margin status is one of the few modifiable factors that a surgeon could possibly manipulate to alter the disease outcome. However, the significance of margin status and margin width...

journal_title：Medicine

authors： Ma KW,Cheung TT,She WH,Chok KSH,Chan ACY,Ng IOL,Chan SC,Lo CM

更新日期：2016-07-01 00:00:00

abstract：:The aim of this study is to report first preliminary results of patients enrolled in a phase II study that will investigate the activity and safety of docetaxel, oxaliplatin, and 5-fluorouracil (DOF) in combination with trastuzumab in human epidermal receptor-2 (HER-2) positive patients with advanced gastric or gastro...

journal_title：Medicine

authors： Roviello G,Petrioli R,Nardone V,Rosellini P,Multari AG,Conca R,Aieta M

更新日期：2018-05-01 00:00:00

abstract：:Intracavitary application of brachytherapy (BT) sources followed by external beam radiation is essential for the local treatment of carcinoma of the cervix, postate, and nasopharynx. Dose distribution of external beam radiation plus BT can be challenging for the planning system because of their dose calculation by 2 d...

journal_title：Medicine

authors： Wang F,Jiang C,Liu T,Sun Q,Ye Z,Shi K,Wu P,Qin W,Fu Z,Jiang Y

更新日期：2020-07-17 00:00:00

abstract：BACKGROUND:Recent studies on physical activity were analyzed by randomizing participants into either the intervention or control group. It is necessary to classify each intervention and control groups according to physical activity using the International Physical Activity Questionnaire (IPAQ). METHODS:This was a pilo...

journal_title：Medicine

authors： Lee CH,Cheung B,Yi GH,Oh B,Oh YH

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Recent studies have demonstrated that coronary microcirculation dysfunction (CMVD) is closely correlated with adverse clinical outcomes. In this study, quantitative stress myocardial contrast echocardiography (MCE) was used to evaluate the CMVD and to investigate its association with the prognosis of patient...

journal_title：Medicine

authors： Yang N,Su YF,Li WW,Wang SS,Zhao CQ,Wang BY,Liu H,Guo M,Han W

更新日期：2019-07-01 00:00:00

abstract：:IgG4-related disease (IgG4-RD) is a novel systemic disease entity characterized by elevated serum IgG4 and tissue infiltration of IgG4-positive plasma cells accompanied by severe fibrosis. Although recent studies demonstrated that innate immune cells including monocytes and macrophages might promote local fibrosis and...

journal_title：Medicine

authors： Ohta M,Moriyama M,Maehara T,Gion Y,Furukawa S,Tanaka A,Hayashida JN,Yamauchi M,Ishiguro N,Mikami Y,Tsuboi H,Iizuka-Koga M,Kawano S,Sato Y,Kiyoshima T,Sumida T,Nakamura S

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The Pharmaceutical industry sponsorship, research outcome and quality has been already evaluated for clinical trials in order to analyze if this kind of sponsorship affects the results of clinical trials. In this sense, this study has the aim to investigate whether placebo use allows positive outcomes regard...

journal_title：Medicine

authors： da Silva JCRA,de Azevedo KPM,Farinasso CM,da Silva DLM,Stefani C,Figueiredo ACMG,de Souza PM,Piuvezam G,Capucho HC

更新日期：2020-10-30 00:00:00

abstract：RATIONALE:Adrenocortical carcinoma is a rare aggressive type of cancer whose prognosis is poor, particularly for metastatic entities. Metastatic adrenocortical carcinoma in the spine is a rare disease with no standard curative managements yet. The objective of this study is to report a very rare case of spinal metastas...

journal_title：Medicine

authors： Liu S,Zhou X,Song A,Huo Z,Wang Y,Liu Y

更新日期：2019-12-01 00:00:00

abstract：:Methemoglobin is a form of hemoglobin that does not bind oxygen. When its concentration is elevated in red blood cells, functional anemia and tissue hypoxia may occur. We performed a retrospective case series to describe the cases of acquired methemoglobinemia (methemoglobin level >2%) detected and the clinical circum...

journal_title：Medicine

authors： Ash-Bernal R,Wise R,Wright SM

更新日期：2004-09-01 00:00:00

abstract：RATIONALE:Immunoglobulin G4 (IgG4)-related hypophysitis is a type of IgG4-related disease (IgG4-RD), which is characterized by plasma cells infiltration in the pituitary causing functional changes and (or) space-occupying effect in the pituitary. IgG4-related hypophysitis is sensitive to hormone therapy in most patient...

journal_title：Medicine

authors： Gu WJ,Zhang Q,Zhu J,Li J,Wei SH,Mu YM

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Diabetic macular edema (DME) can cause severe vision impairments for patients with diabetes. Recently, Conbercept has shown efficacy on DME with 3-monthly loading dose injection and pro re nata (PRN, 3+PRN) thereafter in retrospectivetrials. Furthermore, there are some other approaches have been recommended ...

journal_title：Medicine

authors： Ba T,Zhou L,Zhang H,Zhang X,Guo S,Li H,Tian H,Caihan Q,Bai G,Zhou J,Qi L,Zhang X,Zhang G

更新日期：2020-08-28 00:00:00

abstract：:The aim of the study was to investigate current situation of postoperative pain management in medical institutions in Shandong Province.A questionnaire was developed on the basis of guidelines of acute pain and pain quality assessment scale. The questionnaire was used to obtain information regarding the nature and sca...

journal_title：Medicine

authors： Liu D,Ma J,Zhang Z,Yu A,Chen X,Feng C,Lei W

更新日期：2016-02-01 00:00:00

abstract：:Chronic postsurgical pain (CPSP) is an important clinic problem. It is assessed that prevalence of chronic pain extends to 30% but it is contended that there are various risk factors. We aimed to evaluate the prevalence of chronic pain after hysterectomy, risk factors of chronicity, neuropathic features of pain, and s...

journal_title：Medicine

authors： Beyaz SG,Özocak H,Ergönenç T,Palabıyık O,Tuna AT,Kaya B,Erkorkmaz Ü,Akdemir N

更新日期：2016-08-01 00:00:00

abstract：:Modifiable cardiovascular risk factors such as obesity, hypertension, dyslipidemia, smoking, diabetes mellitus, and metabolic syndrome can easily give rise to coronary heart disease (CHD). However, due to the existence of the so-called "obesity paradox" and "smoking paradox," the impact of these modifiable cardiovascu...

journal_title：Medicine

authors： Bundhun PK,Wu ZJ,Chen MH

更新日期：2015-12-01 00:00:00

abstract：INTRODUCTION:This study is a prospective, assessor-blinded, parallel-group, randomized controlled pilot trial to explore the effectiveness of 12-week adjuvant moxibustion therapy for arthralgia in menopausal females at stage I to III breast cancer on aromatase inhibitor (AI) administration, compared with those receivin...

journal_title：Medicine

authors： Shin S,Jang BH,Park SH,Lee JW,Chae MS,Kim N,Suh HS,Han S,Min SY,Baek SK,Lim YJ,Hwang DS

更新日期：2019-09-01 00:00:00

abstract：:Diabetes mellitus (DM) is prevalent in patients with pancreatic cancer and tends to improve after tumor resection. However, the glycemic response of non-pancreatic cancer patients after surgery has not been examined in detail. We aimed to investigate the changes in glucose metabolism in patients with pancreatic cancer...

journal_title：Medicine

authors： Sohn SY,Lee EK,Han SS,Lee YJ,Hwangbo Y,Kang YH,Lee SD,Kim SH,Woo SM,Lee WJ,Hong EK,Park SJ

更新日期：2018-05-01 00:00:00

abstract：:In the published literature there are controversial data to the biomechanical stability of monocortical comparing to the bicortical fixation of metacarpal fractures. The aim of this study was to compare the biomechanical stability of monocortical and bicortical locking osteosynthesis in quasi-static and dynamic 4-poin...

journal_title：Medicine

authors： Liodaki E,Wendlandt R,Waizner K,Schopp BE,Mailänder P,Stang F

更新日期：2017-07-01 00:00:00

abstract：RATIONALE:Primary malignancy in giant cell tumor of bone (PMGCTB) is extremely unusual. PMGCTB in the thoracic vertebrae is particularly rare. PATIENTS CONCERNS:A 23-year-old man was admitted with a chief complaint of chest pain associated with cough for approximately 3 days. Physical examination revealed a palpable, ...

journal_title：Medicine

authors： Yu H,Shi R,Peng ZG,Yu BH,Cui JL

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Hemorrhoidal disease (HD) is one of the commonest proctologic condition in the general population. Medical therapy for HD has not been formally confirmed due to the inconsistent of results. Liang-Xue-Di-Huang Decoction, a kind of ancient Chinese classical prescription, has been used to treat HD from the 19th...

journal_title：Medicine

authors： Shi SY,Zhou Q,He ZQ,Shen ZF,Zhang WX,Zhang D,Xu CB,Geng J,Wu BS,Chen YG

更新日期：2020-04-01 00:00:00

abstract：RATIONALE:Primary leiomyosarcoma (LMS) of the fallopian tube is extremely uncommon. To the best of our knowledge, so far only 21 cases of primary fallopian tube LMS have been reported in English-language literature. No new case has been reported in the past 7 years. PATIENT CONCERNS:A 44-year-old premenopausal patient...

journal_title：Medicine

authors： You D,Wang Q,Jiang W,Lin L,Yi T,Zhao L,Li M,Wang P

更新日期：2018-04-01 00:00:00

abstract：:Patients with infective endocarditis (IE), have high mortality and morbidity, however, its early diagnosis is difficult. Few studies have examined the delayed diagnosis of IE. We aimed to investigate the factors associated with the diagnostic delay of IE.A retrospective cohort study was conducted for consecutive patie...

journal_title：Medicine

authors： Nishiguchi S,Nishino K,Kitagawa I,Tokuda Y

更新日期：2020-07-24 00:00:00

abstract：RATIONALE:Alström syndrome is an autosomal recessive disorder characterized by hearing loss, blindness, obesity, non-insulin dependent diabetes, and others. PATIENT CONCERN:A 10 years old Saudi girl, who presented with diabetic ketoacidosis and found to have hearing loss and blindness. DIAGNOSIS:Alström syndrome. IN...

journal_title：Medicine

authors： Bakar AA,Kamal NM,Alsaedi A,Turkistani R,Aldosari D

更新日期：2017-03-01 00:00:00

abstract：:T cell immunoglobulin and mucin domain-3 (TIM-3) is a surface molecule expressed on immune cells which play a role in immune regulation. The aims of the present study were to determine whether circulating soluble T cell immunoglobulin domain and mucin-3 (sTIM-3) are elevated in rheumatoid arthritis (RA) patients, and ...

journal_title：Medicine

authors： Matsumoto H,Fujita Y,Asano T,Matsuoka N,Temmoku J,Sato S,Yashiro-Furuya M,Watanabe H,Migita K

更新日期：2020-10-30 00:00:00

abstract：:We evaluate the correlation of clinical staging on positron emission tomography-computed tomography (PET-CT) and pathologic staging and the prognostic value of PET-CT after induction chemotherapy in patients with locally advanced nonsmall cell lung cancer (NSCLC). We analyzed 42 cases of clinical stage IIIA-N2 NSCLC w...

journal_title：Medicine

authors： Kim SH,Lee JH,Lee GJ,Jeong S,Kwak YK,Kim HK,Cho DG,Park YH,Yu M,Yoon SC

更新日期：2015-06-01 00:00:00

abstract：:In Taiwan, the current survival rate 1 year after transplantation exceeds 80%. However, the number of organ/tissue donors per year in Taiwan is extremely low, resulting in increased mortality. This is also true in Europe and in the United States. Recently, data from the Taiwan Organ Registry and Sharing Center showed ...

journal_title：Medicine

authors： Hsieh MH,Shih FJ,Sheu SJ,Wang SS,Shih FJ

更新日期：2018-10-01 00:00:00

abstract：:To determine the association between mammographic density (MD) and the risk of breast cancer (BC) in Chinese women and to investigate the role of fertility risk factors in regulating the relationship between MD and BC.We used Quantra software and the BI-RADS classification to assess MD in 466 patients and 932 controls...

journal_title：Medicine

authors： Wang JM,Zhao HG,Liu TT,Wang FY

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:Knee osteoarthritis (KOA) is a common degenerative joint disorder that affects 250 million people globally. KOA can lead to disability and is often associated with cardiovascular disease, poor quality of life, and mortality. The most common treatment for KOA is non-steroidal anti-inflammatory drug administra...

journal_title：Medicine

authors： Wu SY,Lin CH,Chang NJ,Hu WL,Hung YC,Tsao Y,Kuo CA

更新日期：2020-03-01 00:00:00