Indian Ocean Dipole in CMIP5 and CMIP6: characteristics, biases, and links to ENSO.

abstract：:In this study, we prepared, characterized, and performed toxicity analyses of poly(ε-caprolactone) nanocapsules loaded with neem oil. Three formulations were prepared by the emulsion/solvent evaporation method. The nanocapsules showed a mean size distribution around 400 nm, with polydispersity below 0.2 and were stabl...

journal_title：Scientific reports

authors： Pasquoto-Stigliani T,Campos EVR,Oliveira JL,Silva CMG,Bilesky-José N,Guilger M,Troost J,Oliveira HC,Stolf-Moreira R,Fraceto LF,de Lima R

更新日期：2017-07-19 00:00:00

abstract：:Haemoparasites are responsible for some of the most prevalent and debilitating canine illnesses across the globe, whilst also posing a significant zoonotic risk to humankind. Nowhere are the effects of such parasites more pronounced than in developing countries in the tropics where the abundance and diversity of ectop...

journal_title：Scientific reports

authors： Huggins LG,Koehler AV,Ng-Nguyen D,Wilcox S,Schunack B,Inpankaew T,Traub RJ

更新日期：2019-09-02 00:00:00

abstract：:Increased risk of comorbidities has been reported in Rheumatic and Musculoskeletal Diseases (RMD). We aimed to evaluate the prevalence and pattern of comorbidities in RMD patients nationwide, to identify multimorbidity clusters and to evaluate the gap between recommendations and real screening. Cross-sectional, multic...

journal_title：Scientific reports

authors： Ziade N,El Khoury B,Zoghbi M,Merheb G,Abi Karam G,Mroue' K,Messaykeh J

更新日期：2020-05-06 00:00:00

abstract：:We present a detailed experimental and theoretical study of the acoustic phonon modes in rolled-up multilayers with thickness of the layers in the nanometre and diameters in the micrometre range. We compare our results to planar, unrolled multilayers grown by molecular beam epitaxy. For the planar multilayers the expe...

journal_title：Scientific reports

authors： Brick D,Engemaier V,Guo Y,Grossmann M,Li G,Grimm D,Schmidt OG,Schubert M,Gusev VE,Hettich M,Dekorsy T

更新日期：2017-07-14 00:00:00

abstract：:Circular RNAs (circRNAs) are abundantly expressed in the haematopoietic compartment, but knowledge on their diversity among blood cell types is still limited. Nevertheless, emerging data indicate an array of circRNA functions exerted through interactions with other RNAs and proteins, by translation into peptides, and ...

journal_title：Scientific reports

authors： Gaffo E,Boldrin E,Dal Molin A,Bresolin S,Bonizzato A,Trentin L,Frasson C,Debatin KM,Meyer LH,Te Kronnie G,Bortoluzzi S

更新日期：2019-10-11 00:00:00

abstract：:Medicinal herbs belonging to the same genus are always easily confused due to their extremely similar morphology and metabolites. Previously, to differentiate them, inherently specific biomarkers were screened out via intuitive comparison of their metabolite profiles. Unfortunately, the selected biomarkers have worked...

journal_title：Scientific reports

authors： Wang HP,Liu Y,Chen C,Xiao HB

更新日期：2017-07-04 00:00:00

abstract：:Although a slowing of electroencephalographic (EEG) activity during wakefulness and -to some extent- sleep of Alzheimer disease (AD) patients (i.e., increased slow-frequency activity) was documented, recent findings in healthy elderly show a decreased 0.6-1 Hz slow wave activity (SWA) during NREM, which was associated...

journal_title：Scientific reports

authors： De Gennaro L,Gorgoni M,Reda F,Lauri G,Truglia I,Cordone S,Scarpelli S,Mangiaruga A,D'atri A,Lacidogna G,Ferrara M,Marra C,Rossini PM

更新日期：2017-01-03 00:00:00

abstract：:Macro- and micro-environmental factors modulate parasite loads in fish, determining parasitic abundances, diversity, and interaction dynamics. In this study, seasonal variations in larval ectoparasites on fish larvae in the northern Humboldt Current System (HCS) were evaluated using a delta-gamma generalized linear mo...

journal_title：Scientific reports

authors： Paredes LD,Landaeta MF,Molinet C,González MT

更新日期：2021-01-12 00:00:00

abstract：:A central challenge in designing and administering effective anticoagulants is achieving the proper therapeutic window and dosage for each patient. The Hill coefficient, nH, which measures the steepness of a dose-response relationship, may be a useful gauge of this therapeutic window. We sought to measure the Hill coe...

journal_title：Scientific reports

authors： Chang JB,Quinnies KM,Realubit R,Karan C,Rand JH,Tatonetti NP

更新日期：2016-07-21 00:00:00

abstract：:Oligomerization of protein into specific quaternary structures plays important biological functions, including regulation of gene expression, enzymes activity, and cell-cell interactions. Here, we report the determination of two crystal structures of the Grimontia hollisae (formally described as Vibrio hollisae) therm...

journal_title：Scientific reports

authors： Wang YK,Huang SC,Chang CY,Huang WT,Liao MJ,Yip BS,Chou FP,Li TT,Wu TK

更新日期：2019-07-08 00:00:00

abstract：:Direct measures of energy expenditure are difficult to obtain in marine mammals, and accelerometry may be a useful proxy. Recently its utility has been questioned as some analyses derived their measure of activity level by calculating the sum of accelerometry-based values and then comparing this summation to summed (t...

journal_title：Scientific reports

authors： Ladds MA,Rosen DAS,Slip DJ,Harcourt RG

更新日期：2017-09-18 00:00:00

abstract：:Neurodevelopmental changes occur with asymmetric hearing loss, limiting binaural/spatial hearing and putting children at risk for social and educational challenges. These deficits may be mitigated by providing bilateral hearing in children through auditory prostheses. Effects on speech perception and spatial hearing w...

journal_title：Scientific reports

authors： Polonenko MJ,Papsin BC,Gordon KA

更新日期：2018-09-04 00:00:00

abstract：:Metastasis suppressor genes (MS genes) are genes that play important roles in inhibiting the process of cancer metastasis without preventing growth of the primary tumor. Identification of these genes and understanding their functions are critical for investigation of cancer metastasis. Recent studies on cancer metasta...

journal_title：Scientific reports

authors： Zhao M,Li Z,Qu H

更新日期：2015-10-21 00:00:00

abstract：:Unlike the constant nature of elastic coefficients of isotropic bulk materials, the Young's (E) and shear (μ) moduli of nano-structured (NS) gyroid metamaterials change with relative density (ρ), but at different rates depending on the cell size of the structure. These elastic behaviors displayed by E and μ cause cros...

journal_title：Scientific reports

authors： Park JH,Lee JC

更新日期：2017-09-05 00:00:00

abstract：:Neutrophil gelatinase-associated lipocalin (NGAL) is involved in cardiovascular and renal diseases. Gene inactivation of NGAL blunts the pathophysiological consequences of cardiovascular and renal damage. We aimed to design chemical NGAL inhibitors and investigate its effects in experimental models of myocardial infar...

journal_title：Scientific reports

authors： Bonnard B,Martínez-Martínez E,Fernández-Celis A,Pieronne-Deperrois M,Do QT,Ramos I,Rossignol P,Zannad F,Mulder P,Ouvrard-Pascaud A,López-Andrés N,Jaisser F

更新日期：2021-01-28 00:00:00

abstract：:Sphingobium sp. strain TCM1 can degrade tris(2-chloroethyl) phosphate (TCEP) to inorganic phosphate and 2-chloroethanol. A phosphotriesterase (PTE), phosphodiesterase (PDE) and phosphomonoesterase (PME) are believed to be involved in the degradation of TCEP. The PTE and PME that respectively catalyze the first and thi...

journal_title：Scientific reports

authors： Abe K,Mukai N,Morooka Y,Makino T,Oshima K,Takahashi S,Kera Y

更新日期：2017-06-06 00:00:00

abstract：:In the last decades, AC powered atmospheric dielectric barrier discharges (DBDs) in air with a liquid electrode have been proposed as a promising plasma technology with versatile applicability in medicine, agriculture and water treatment. The fundamental features of the micro-discharge filaments that make up this type...

journal_title：Scientific reports

authors： Vanraes P,Nikiforov A,Bogaerts A,Leys C

更新日期：2018-07-19 00:00:00

abstract：:Despite improvements in systemic therapy options for renal cancer, it remains one of the most drug-resistant malignancies. Interestingly, reports have shown that kahweol and cafestol, natural diterpenes extracted from coffee beans, exhibit anti-cancer activity. However, the multiple potential pharmacological actions o...

journal_title：Scientific reports

authors： Makino T,Izumi K,Hiratsuka K,Kano H,Shimada T,Nakano T,Kadomoto S,Naito R,Iwamoto H,Yaegashi H,Shigehara K,Kadono Y,Nakata H,Saito Y,Nakagawa-Goto K,Sakai N,Iwata Y,Wada T,Mizokami A

更新日期：2021-01-12 00:00:00

abstract：:It is possible to accurately and economically predict change in protein-protein interaction energy upon mutation (ΔΔG), when a high-resolution structure of the complex is available. This is of growing usefulness for design of high-affinity or otherwise modified binding proteins for therapeutic, diagnostic, industrial,...

journal_title：Scientific reports

authors： Dourado DF,Flores SC

更新日期：2016-05-13 00:00:00

abstract：:Novelty seeking (NS) is a personality trait reflecting excitement in response to novel stimuli. High NS is usually a predictor of risky behaviour such as drug abuse. However, the relationships between NS and risk-related cognitive processes, including individual risk preference and the brain activation associated with...

journal_title：Scientific reports

authors： Wang Y,Liu Y,Yang L,Gu F,Li X,Zha R,Wei Z,Pei Y,Zhang P,Zhou Y,Zhang X

更新日期：2015-06-11 00:00:00

abstract：:Three-dimensional ion and particle concentrations under hydrodynamic focusing in a Y-shaped square microchannel are numerically simulated to clarify the decrease of the ion concentration along the flow direction within the focused particle stream. The simulation model is theoretically governed by the laminar flow and ...

journal_title：Scientific reports

authors： Sato N,Kawashima D,Takei M

更新日期：2021-01-28 00:00:00

abstract：:CRISPR/Cas9 genome editing has revolutionized functional genomics in vertebrates. However, CRISPR/Cas9 edited F0 animals too often demonstrate variable phenotypic penetrance due to the mosaic nature of editing outcomes after double strand break (DSB) repair. Even with high efficiency levels of genome editing, phenotyp...

journal_title：Scientific reports

authors： Naert T,Tulkens D,Edwards NA,Carron M,Shaidani NI,Wlizla M,Boel A,Demuynck S,Horb ME,Coucke P,Willaert A,Zorn AM,Vleminckx K

更新日期：2020-09-04 00:00:00

abstract：:Depressive disorder (DD) is a mental illness affecting more than 300 million people worldwide, whereas social stigma and subtle, variant symptoms impede diagnosis. Psychomotor retardation is a common component of DD with a negative impact on motor function, usually reflected on patients' routine activities, including,...

journal_title：Scientific reports

authors： Mastoras RE,Iakovakis D,Hadjidimitriou S,Charisis V,Kassie S,Alsaadi T,Khandoker A,Hadjileontiadis LJ

更新日期：2019-09-16 00:00:00

abstract：:The differential conductance of graphene is shown to exhibit a zero-bias anomaly at low temperatures, arising from a suppression of the quantum corrections due to weak localization and electron interactions. A simple rescaling of these data, free of any adjustable parameters, shows that this anomaly exhibits a univers...

journal_title：Scientific reports

authors： Somphonsane R,Ramamoorthy H,He G,Nathawat J,Yin S,Kwan CP,Arabchigavkani N,Barut B,Zhao M,Jin Z,Fransson J,Bird JP

更新日期：2020-03-27 00:00:00

abstract：:ADHD is a major societal problem with increasing incidence and a stagnant track record for treatment advances. A lack of appropriate animal models has partly contributed to the incremental advance of this field. Hence, our goal was to generate a novel mouse model that could be useful for ADHD medication development. W...

journal_title：Scientific reports

authors： Majdak P,Ossyra JR,Ossyra JM,Cobert AJ,Hofmann GC,Tse S,Panozzo B,Grogan EL,Sorokina A,Rhodes JS

更新日期：2016-12-20 00:00:00

abstract：:Water-soluble protein content (WSPC) is a critical factor in both soybean protein quality and functionality. However, the underlying genetic determinants are unclear. Here, we used 219 soybean accessions and 152 recombinant inbred lines genotyped with high-density markers and phenotyped in multi-environments to dissec...

journal_title：Scientific reports

authors： Zhang D,Lü H,Chu S,Zhang H,Zhang H,Yang Y,Li H,Yu D

更新日期：2017-07-11 00:00:00

abstract：:Exendin-4 is a long acting glucagon-like peptide 1 (GLP-1) analogue that is an agonist for the GLP-1 receptor, a G-protein coupled receptor (GPCR). Exendin-4 is used to clinically improve glucose tolerance in diabetic patients due to its ability to enhance insulin secretion. In rodents, and possibly in humans, exendin...

journal_title：Scientific reports

authors： Fusco J,Xiao X,Prasadan K,Sheng Q,Chen C,Ming YC,Gittes G

更新日期：2017-08-22 00:00:00

abstract：:Accumulating evidence indicates the absence of paternally derived miRNAs, piwiRNAs, and proteins may be one important factor contributing to developmental failure in somatic cell cloned embryos. In the present study, we found microRNA-449b (miR-449b) was highly expressed in sperm. Target gene predictions and experimen...

journal_title：Scientific reports

authors： Wang M,Gao Y,Qu P,Qing S,Qiao F,Zhang Y,Mager J,Wang Y

更新日期：2017-10-17 00:00:00

abstract：:Microbial rhodopsin is a photoreceptor protein found in various bacteria and archaea, and it is considered to be a light-utilization device unique to heterotrophs. Recent studies have shown that several cyanobacterial genomes also include genes that encode rhodopsins, indicating that these auxiliary light-utilizing pr...

journal_title：Scientific reports

authors： Hasegawa M,Hosaka T,Kojima K,Nishimura Y,Nakajima Y,Kimura-Someya T,Shirouzu M,Sudo Y,Yoshizawa S

更新日期：2020-10-07 00:00:00

abstract：:Triterpenic acids (TAs), a large group of natural compounds with diverse biological activity, are produced by several plant taxa. Betulinic, oleanolic, and ursolic acids are the most medicinally important TAs and are mainly found in plants of the mint family. Metabolic engineering is strongly dependent on identifying ...

journal_title：Scientific reports

authors： Aminfar Z,Rabiei B,Tohidfar M,Mirjalili MH

更新日期：2019-11-01 00:00:00