Abstract:
:A lag in the increase in oxygen consumption (MO2 ) occurs at the start of sustainable exercise in trout. Waterborne dichloroacetate (0.58 and 3.49 mmol l-1 ), a compound which activates pyruvate dehydrogenase (PDH) by inhibiting PDH kinase in muscle, accelerates the increase in MO2 during the first 10 min of sustainable exercise when velocity is elevated to 75% critical swimming speed in a swim tunnel. There are no effects on MO2 thereafter or at rest. This indicates that a delay in PDH activation ("metabolic inertia") contributes to the lag phenomenon.
journal_name
J Fish Bioljournal_title
Journal of fish biologyauthors
Wood CM,Pane EF,Heigenhauser GJFdoi
10.1111/jfb.14461subject
Has Abstractpub_date
2020-10-01 00:00:00pages
1242-1246issue
4eissn
0022-1112issn
1095-8649journal_volume
97pub_type
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