Accuracy of prehospital point-of-care lactate in early in-hospital mortality.

abstract：:Studies were designed to establish the acid inhibitory potency and plasma kinetics of somatostatin-28 (S-28) in humans and to determine whether the amount of S-28 released into the circulation after a meal is sufficient to regulate gastric acid secretion. A liquid meal induced a significant increase of S-28 (P < 0.01)...

journal_title：European journal of clinical investigation

authors： Hildebrand P,Ensinck JW,Buettiker J,Drewe J,Burckhardt B,Gyr K,Beglinger C

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:The intestinal mucosa of patients with inflammatory bowel diseases (IBD) characteristically shows a high degree of inflammation when compared to healthy subjects. This appears to be attributable to an imbalance in local reactivity of inflammatory cells. In the present study, we tested the hypothesis that imm...

journal_title：European journal of clinical investigation

authors： Kovarik JJ,Tillinger W,Hofer J,Hölzl MA,Heinzl H,Saemann MD,Zlabinger GJ

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Diabetes dramatically increases the risk of cardiovascular complications and mortality. Hydrogen sulphide plays an important role in reducing oxidative stress. Several studies demonstrated that hydrogen sulphide protects islet beta cells from oxidant stress damage and decreases apoptosis. The aim of...

journal_title：European journal of clinical investigation

authors： Dorofeyeva N,Drachuk K,Rajkumar R,Sabnis O,Sagach V

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Increased production of chemokines by adipose tissue and defective adipose tissue oxygenation as a result of obesity may induce leucocyte infiltration and subsequent systemic inflammation. OBJECTIVES:1-To determine the relation between the amount of visceral and subcutaneous adipose tissue and the chemokine...

journal_title：European journal of clinical investigation

authors： Faber DR,van der Graaf Y,Westerink J,Kanhai DA,Monajemi H,Visseren FL,SMART study Group.

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Based on a report of a marked increase in the erythropoietin concentration ([EPO]) a few hours after the cessation of a single 2-h session of O(2) breathing, short periods of O(2) administration have been advocated as a therapy for anaemia. Accordingly, the purpose of the present study was to evaluate this t...

journal_title：European journal of clinical investigation

authors： Keramidas ME,Norman B,Gustafsson T,Eiken O,Mekjavic IB

更新日期：2012-03-01 00:00:00

abstract：:The concentrations of gastrins containing the active C-terminal tetrapeptide amide (mainly gastrin-34 and gastrin-17) and the N-terminal tridecapeptide fragment of gastrin-17 were measured in antral and duodenal biopsy specimens. The antral concentration of the N-terminal gastrin fragment was much higher in patients w...

journal_title：European journal of clinical investigation

authors： Petersen B,Andersen BN

更新日期：1984-06-01 00:00:00

abstract：:Currently available information on adipose tissue metabolism in man is mainly based on studies in vitro. In the present work adipose tissue lipid uptake was studied in vivo in man. 100 g glucose and 120 g milk fat with 10 microCi U-14C oleic acid were given in the overnight fasting state to eight women and 2 h after a...

journal_title：European journal of clinical investigation

authors： Mårin P,Rebuffé-Scrive M,Björntorp P

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:The mammalian target of rapamycin (mTOR) has recently been implicated in leukaemic cell growth, tumour-associated angiogenesis and expression of vascular endothelial growth factor (VEGF). We examined whether mTOR plays a role as regulator of growth and VEGF-expression in acute myeloid leukaemia (AML). Three ...

journal_title：European journal of clinical investigation

authors： Böhm A,Aichberger KJ,Mayerhofer M,Herrmann H,Florian S,Krauth MT,Derdak S,Samorapoompichit P,Sonneck K,Vales A,Gleixner KV,Pickl WF,Sperr WR,Valent P

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Mitochondria are dynamic organelles that participate in energy conversion, metabolism, signaling and apoptosis. To fulfill their multiple tasks, mitochondria come in varied morphologies and ultrastructures resulting from the equilibrium between fusion and fission, Furthermore, they are in close contact with ...

journal_title：European journal of clinical investigation

authors： Scorrano L

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Early detection of fungal infection is essential for beginning of prompt and specific therapy. In this study we describe a rapid and sensitive procedure to detect, by polymerase chain reaction (PCR) assays, a wide range of medically important opportunistic and pathogenic fungi in dermal specimens from dermat...

journal_title：European journal of clinical investigation

authors： Turin L,Riva F,Galbiati G,Cainelli T

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Experimental and clinical studies have suggested that inhibitors of the renin angiotensin system (RAS) might be useful to slow the progression of valvular calcification in patients with aortic stenosis (AS). OBJECTIVES:The aim of this study was to evaluate the relationships between the weight and tissue rem...

journal_title：European journal of clinical investigation

authors： Côté N,Couture C,Pibarot P,Després JP,Mathieu P

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Analytical statistics revealed a variety of risk factors for hypertension, but the complex interplay between different factors remains to be determined by more powerful statistical techniques. METHODS:Analytical as well as new, explorative statistical methods such as natural segmentation (k-means) and predi...

journal_title：European journal of clinical investigation

authors： Lukas A,Kumbein F,Temml C,Mayer B,Oberbauer R

更新日期：2003-03-01 00:00:00

abstract：:We evaluated the influence of family history of hypertension on insulin sensitivity in lean and obese hypertensive subjects (H): 40 lean [body mass index (BMI) < or = 25 kg m-2] H with normotensive parents (F-), 50 lean H with one or two parents hypertensive (F+), 30 obese HF- (BMI > or = 30 kg m-2) and 35 obese HF+. ...

journal_title：European journal of clinical investigation

authors： Grandi AM,Gaudio G,Fachinetti A,Zanzi P,Bianchi L,Ceriani L,Guasti L,Venco A

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVES:EPB4.1 has been previously mapped to human chromosome 1p33-p34.2. In contradiction to this chromosomal location, we have mapped EPB4.1-1p36 by using fluorescence in situ hybridization and radiation hybrid mapping. In neuroblastomas, deletions of the telomeric end of chromosome 1 (1p36) are the most common ge...

journal_title：European journal of clinical investigation

authors： Huang S,Lichtenauer UD,Pack S,Wang C,Kim AC,Lutchman M,Koch CA,Torres-Cruz J,Huang SC,Benz EJ Jr,Christiansen H,Dockhorn-Dworniczak B,Poremba C,Vortmeyer AO,Chishti AH,Zhuang Z

更新日期：2001-10-01 00:00:00

abstract：:We have reported that the disorder of lipoprotein metabolism in hyperalphalipoproteinaemic patients with a deficiency of cholesteryl ester transfer protein (CETP) is characterized by the polydisperse low density lipoprotein (LDL) particles and the accumulation of cholesteryl ester (CE) in high density lipoprotein (HDL...

journal_title：European journal of clinical investigation

authors： Sakai N,Yamashita S,Hirano K,Ishigami M,Arai T,Kobayashi K,Funahashi T,Matsuzawa Y

更新日期：1995-05-01 00:00:00

abstract：:Tumours in the adrenals originate from the adrenal cortex, the adrenal medulla or as metastases from extra-adrenal primaries. Differentiating between these three groups is the first task a pathologist has to tackle when dealing with specimens from the adrenal region. Whereas this is possible in every case with total r...

journal_title：European journal of clinical investigation

authors： Saeger W

更新日期：2000-12-01 00:00:00

abstract：:Microdialysis was used to selectively assess the effect of the paracrine renin-angiotensin system (RAS) on interstitial glucose and lactate concentration profiles in skeletal muscle of healthy volunteers (n = 8) during basal and insulin-stimulated conditions. Paracrine RAS was selectively inhibited by local retrodialy...

journal_title：European journal of clinical investigation

authors： Müller M,Fasching P,Schmid R,Burgdorff T,Waldhäusl W,Eichler HG

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Several studies have suggested that chronic obstructive pulmonary disease (COPD) could be predictive of the prognosis in patients with heart failure (HF), but yield conflicting findings. Therefore, we conducted a meta-analysis to examine the impact of COPD on adverse outcomes in patients with HF. METHODS:We...

journal_title：European journal of clinical investigation

authors： Xu S,Ye Z,Ma J,Yuan T

更新日期：2021-01-01 00:00:00

abstract：:Sporadic hypophosphataemic osteomalacia (adult-onset type) was demonstrated in a 40-year-old man on the basis of severe osteomalacia, hypophosphataemia, hyperphosphaturia and glycinuria. Plasma immunoreactive parathyroid hormone (iPTH) concentration was 9.3 ng prot./ml (normal range: 4-8 ng prot./ml). Plasma 25-hydrox...

journal_title：European journal of clinical investigation

authors： Ulmann A,Bouchard P,Garabédian M,Bourdeau A,Witmer-Cournot G,Lacour B,Balsan S,Funck-Brentano JL

更新日期：1980-10-01 00:00:00

abstract：:The change in bone mass during 1 1/2 years was determined in a longitudinal study of sixty adult insulin-treated diabetic out-patients. During the study period the mean bone mass decreased by 1.30 +/- 0.28 (SEM)% (P less than 0.001), to a mean value of 91.0 +/- 1.7% of normal (P less than 0.001). The rate of bone loss...

journal_title：European journal of clinical investigation

authors： McNair P,Christiansen C,Christensen MS,Madsbad S,Faber OK,Binder C,Transbøl I

更新日期：1981-02-01 00:00:00

abstract：:Dipyrone metabolites 4-methylaminoantipyrine (MAA) and 4-formylaminoantipyrine (FAA) as well as acetylsalicylic acid inhibited neutrophil migration toward zymosan-activated serum. Inhibition was maximal (76.8 +/- 19.0; 79.2 +/- 12.5 and 80.0 +/- 4.4%, respectively, P less than 0.003) when suboptimal concentrations (0....

journal_title：European journal of clinical investigation

authors： Matzner Y,Drexler R,Levy M

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:We hypothesized the existence of different hormonal response patterns to repeated lower body negative pressure (LBNP) and head-up tilt (HUT) in healthy males. We compared hormonal, cardiovascular and plasma volume changes from rest to stress within- and between-LBNP and HUT applications. Hormones investigate...

journal_title：European journal of clinical investigation

authors： Roessler A,Goswami N,Haditsch B,Loeppky JA,Luft FC,Hinghofer-Szalkay H

更新日期：2011-08-01 00:00:00

abstract：AIM:Observationally, low serum testosterone among men is associated with cardiovascular diseases and its risk factors, but it is unclear whether raising endogenous androgens would be protective. To clarify the role of androgens, the association of two different androgen biomarkers (serum testosterone and androstanediol...

journal_title：European journal of clinical investigation

authors： Schooling CM

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Cancer is often caused by disturbance in the regulation and/or execution of programmed cell death (PCD, including apoptosis and autophagy). Our aim was to investigate these two pathways simultaneously in the same samples to understand further the pathological roles of PCDs in colorectal cancer. MATERIALS AN...

journal_title：European journal of clinical investigation

authors： Chang YT,Tseng HC,Huang CC,Chen YP,Chiang HC,Chou FP

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The investigation of the human follicle fluid proteome has gained much interest in the search of new markers as predictors for in vitro fertilization and intracytoplasmic sperm injection (IVF/ICSI) treatment outcome. Follicular fluid folate, as substrate of one carbon (1-C) metabolism, affects follicular met...

journal_title：European journal of clinical investigation

authors： Twigt JM,Bezstarosti K,Demmers J,Lindemans J,Laven JS,Steegers-Theunissen RP

更新日期：2015-08-01 00:00:00

abstract：:A kindred in which several members have otherwise typical acute intermittent porphyria but normal erythrocyte uroporphyrinogen-I-synthase activity has been described from Finland. We studied two porphyric members of this kindred, two patients with typical acute intermittent porphyria, and two healthy controls using th...

journal_title：European journal of clinical investigation

authors： Mustajoki P,Tenhunen R

更新日期：1985-10-01 00:00:00

abstract：:As increased oxidative stress is probably a pathogenetic factor in the development of diabetic complications, we studied nerve function and endogenous antioxidants in plasma, erythrocytes and sciatic nerve of untreated and insulin-treated streptozotocin-diabetic rats. After 18 weeks, the diabetes-induced sciatic nerve...

journal_title：European journal of clinical investigation

authors： van Dam PS,Bravenboer B,van Asbeck BS,van Oirschot JF,Marx JJ,Gispen WH

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:To evaluate comprehensively the effects of 12 prophylaxis interventions for secondary prophylaxis of variceal bleeding using multiple-treatments meta-analysis. METHODS:PubMed, EMBASE and the Cochrane Library were searched prior to November 2011. Randomized controlled trials (RCTs) comparing the interventions...

journal_title：European journal of clinical investigation

authors： Shi KQ,Liu WY,Pan ZZ,Ling XF,Chen SL,Chen YP,Fan YC,Zheng MH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Cardioprotective effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) of marine origin are well recognized. Because of the shortness of marine resources vegetable oils are increasingly used in fish farming. The effects on human health of fish fed on vegetable oils are largely unknown. METHODS:In a dou...

journal_title：European journal of clinical investigation

authors： Seierstad SL,Seljeflot I,Johansen O,Hansen R,Haugen M,Rosenlund G,Frøyland L,Arnesen H

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Disuse and/or local inflammation in the muscle cannot be excluded as potential influences for the decreased muscle force in patients hospitalised due to an acute chronic obstructive pulmonary disease (COPD) exacerbation. This study aims to compare expression levels of markers of disuse (insulin-like growth f...

journal_title：European journal of clinical investigation

authors： Crul T,Spruit MA,Gayan-Ramirez G,Quarck R,Gosselink R,Troosters T,Pitta F,Decramer M

更新日期：2007-11-01 00:00:00