Abstract:
INTRODUCTION:Due to overcome the hardness of the vaccine design, computational vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing analysis, antigenicity analysis, population coverage, conservancy analysis, allergenicity assessment, toxicity prediction, and protein-peptide docking are important steps in the process of designing and developing potent vaccines against various viruses and cancers. In order to perform all of the analyses, several bioinformatics tools and online web servers have been developed. Scientists must take the decision to apply more suitable and precise servers for each part based on their accuracy. AREAS COVERED:In this review, a wide-range list of different bioinformatics tools and online web servers has been provided. Moreover, some studies were proposed to show the importance of various bioinformatics tools for predicting and developing efficient vaccines against different pathogens including viruses, bacteria, parasites, and fungi as well as cancer. EXPERT OPINION:Immunoinformatics is the best way to find potential vaccine candidates against different pathogens. Thus, the selection of the most accurate tools is necessary to predict and develop potent preventive and therapeutic vaccines. To further evaluation of the computational and in silico vaccine design, in vitro/in vivo analyses are required to develop vaccine candidates.
journal_name
Expert Rev Vaccinesjournal_title
Expert review of vaccinesauthors
Kardani K,Bolhassani A,Namvar Adoi
10.1080/14760584.2020.1794832subject
Has Abstractpub_date
2020-08-01 00:00:00pages
699-726issue
8eissn
1476-0584issn
1744-8395journal_volume
19pub_type
杂志文章abstract::Introduction: Influenza vaccination is regarded as the most effective way to prevent influenza infection. Due to the rapid genetic changes that influenza viruses undergo, seasonal influenza vaccines must be reformulated and re-administered annually necessitating the evaluation of influenza vaccine effectiveness (VE) e...
journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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更新日期:2017-10-01 00:00:00
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journal_title:Expert review of vaccines
pub_type: 传,历史文章,面试
doi:10.1586/14760584.2013.836913
更新日期:2013-10-01 00:00:00
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journal_title:Expert review of vaccines
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journal_title:Expert review of vaccines
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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journal_title:Expert review of vaccines
pub_type: 杂志文章,meta分析,评审
doi:10.1080/14760584.2018.1433999
更新日期:2018-04-01 00:00:00
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更新日期:2020-04-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1586/erv.10.161
更新日期:2011-02-01 00:00:00
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journal_title:Expert review of vaccines
pub_type: 评论,杂志文章
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更新日期:2012-03-01 00:00:00
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journal_title:Expert review of vaccines
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pub_type: 社论
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journal_title:Expert review of vaccines
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journal_title:Expert review of vaccines
pub_type: 社论
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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更新日期:2010-03-01 00:00:00
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journal_title:Expert review of vaccines
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
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journal_title:Expert review of vaccines
pub_type: 杂志文章
doi:10.1586/14760584.7.4.431
更新日期:2008-05-01 00:00:00
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journal_title:Expert review of vaccines
pub_type: 杂志文章,评审
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