Lobectomy versus sublobar resection in patients with non-small cell lung cancer: a systematic review.

Abstract:

:Surgery is the gold standard treatment of lung cancer. The minimally invasive technique does not only concern access to the chest but also the limits of parenchymal resection. The study debates on the safety and oncological adequacy of sublobar resections in bronchogenic carcinoma patients. A systematic analysis of the data in the literature was carried out, comparing the outcomes of patients with resectable non-small lung cancer (NSCLC) who underwent lobectomy or sublobar resection. These last interventions include both segmentectomies and wedge resections taking into consideration the following parameters: complications, relapse rate and overall survival. The complication rate is higher in patients underwent lobectomy compared to sublobar resection, especially in presence of high comorbidity index or octogenarian patients (overall values respectively between 0 and 48% and 0 and 46.6%). Contrarily, the relapse rate (6.2% to 32% vs. 3.6% to 53.4%) and overall survival (50.2% to 93.8% vs. 38.6% to 100%) are more favorable in patients undergoing lobectomy. Sublobar resections are particularly indicated in elderly patients and in patients with high comorbidity index or reduced respiratory functional reserve. However, pulmonary lobectomy still remains the safest and oncologically correct method in patients with good performance status or higher risk of recurrence.

journal_name

J Thorac Dis

authors

Divisi D,De Vico A,Zaccagna G,Crisci R

doi

10.21037/jtd.2020.02.54

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

3357-3362

issue

6

eissn

2072-1439

issn

2077-6624

pii

jtd-12-06-3357

journal_volume

12

pub_type

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