Abstract：
:Natural hazards including floods can trigger catastrophic failures in interdependent urban transport network-of-networks (NoNs). Population growth has enhanced transportation demand while urbanization and climate change have intensified urban floods. However, despite the clear need to develop actionable insights for improving the resilience of critical urban lifelines, the theory and methods remain underdeveloped. Furthermore, as infrastructure systems become more intelligent, security experts point to the growing threat of targeted cyber-physical attacks during natural hazards. Here we develop a hypothesis-driven resilience framework for urban transport NoNs, which we demonstrate on the London Rail Network (LRN). We find that topological attributes designed for maximizing efficiency rather than robustness render the network more vulnerable to compound natural-targeted disruptions including cascading failures. Our results suggest that an organizing principle for post-disruption recovery may be developed with network science principles. Our findings and frameworks can generalize to urban lifelines and more generally to real-world spatial networks.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Yadav N,Chatterjee S,Ganguly ARdoi
10.1038/s41598-020-66049-ysubject
Has Abstractpub_date
2020-06-25 00:00:00pages
10350issue
1issn
2045-2322pii
10.1038/s41598-020-66049-yjournal_volume
10pub_type
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pub_type： 杂志文章
doi：10.1038/s41598-019-46870-w
更新日期：2019-07-22 00:00:00
abstract：:Natural killer (NK) cells are essential for immunosurveillance against transformed cells. Transient receptor potential melastatin 2 (TRPM2) is a Ca(2+)-permeable cation channel gated by ADP-ribose (ADPR). However, the role of TRPM2-mediated Ca(2+) signaling in the antitumor response of NK cells has not been explored. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09482
更新日期：2015-03-25 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19275
更新日期：2016-01-14 00:00:00
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pub_type： 杂志文章
doi：10.1038/s41598-020-60198-w
更新日期：2020-02-26 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25697-x
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1038/s41598-018-23031-z
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pub_type： 杂志文章
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更新日期：2015-09-18 00:00:00
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pub_type： 杂志文章
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更新日期：2018-07-13 00:00:00
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pub_type： 杂志文章
doi：10.1038/s41598-019-45795-8
更新日期：2019-06-28 00:00:00
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journal_title：Scientific reports
pub_type： 已发布勘误
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更新日期：2018-03-19 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-51624-9
更新日期：2019-10-23 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69721-5
更新日期：2020-07-31 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11918
更新日期：2015-07-09 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28812
更新日期：2016-07-05 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17615-4
更新日期：2017-12-18 00:00:00
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pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章,多中心研究
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pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2019-04-17 00:00:00
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pub_type： 杂志文章
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更新日期：2019-12-27 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2019-10-14 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2015-11-10 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-54586-0
更新日期：2019-11-29 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78995-8
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25782
更新日期：2016-05-12 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50283-0
更新日期：2019-10-01 00:00:00
