Abstract：
BACKGROUND:The aim of this study was to evaluate the effects of the standardized supplement Robuvit® (oak wood extract) in defined diffuse, minimal lymphatic "retention" (DMLR). METHODS:Robuvit® has already been investigated in both primary and secondary (post-surgical, post chemo-radiotherapy) lymphatic insufficiency. This registry included subjects with diffuse, minimal lymphatic "retention" (DMLR). The registry management groups included women with mild-moderate limb swelling using standard management (SM) as controls. A second, comparable group used prevention with Robuvit® at the dosage of 3 cp/day (300 mg/day) for 4 weeks. RESULTS:No tolerability problems or side effects were observed with the preventive supplementation. The management groups (34 women in total), including 18 women in Robuvit® and 16 in SM were comparable in age and baseline evaluations. After 4 weeks, in the Robuvit® group, edema scale values derived from ultrasound observations decreased significantly (P<0.05) at all measurement's sites, from the proximal (inguinal) level to the more distal (ankle-foot) level. No significant changes in edema were observed in control subjects. Generally, in areas with higher level of edema (distal areas at the foot and ankle), the edema decrease was larger than in more proximal, ultrasound measurement sites. CONCLUSIONS:Preventive Robuvit® supplementation appears to be safe and effective in controlling DMLR in subjects without significant or apparent clinical conditions. This preventive, concept study should be extended to a larger population for more meaningful observations.
journal_name
Minerva Cardioangioljournal_title
Minerva cardioangiologicaauthors
Hu S,Belcaro G,Hosoi M,Cesarone MR,Scipione V,Scipione C,Dugall M,Feragalli B,Cotellese R,Maione Cdoi
10.23736/S0026-4725.19.05026-6subject
Has Abstractpub_date
2020-06-01 00:00:00pages
197-202issue
3eissn
0026-4725issn
1827-1618pii
S0026-4725.19.05026-6journal_volume
68pub_type
杂志文章abstract：:Atrial fibrillation is the most common sustained cardiac arrhythmia and with an aging population its prevalence will increase. In addition to appropriate anticoagulation to reduce the thromboembolic risk, there has been an increasing need for a personalized approach in identifying which patients are likely to benefit ...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
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abstract：:Recent studies have demonstrated the usefulness of myocardial contrast echocardiography (MCE) in studying myocardial perfusion. Several first and second generation contrast agent such as Levovist, Sonovue, Optison, Definity and Imagent are commercially available or close to be introduced into the market. Use of MCE al...
journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2003-12-01 00:00:00
abstract：:We assessed the safety and efficacy of intravenous propafenone in the treatment of atrial fibrillation and flutter of recent onset (1-10 days). The drug was administered, at a dosage of 2 mg/kg, to 46 consecutive patients (with age variable from 35 to 86 years), 36 with atrial fibrillation, 10 with atrial flutter. The...
journal_title：Minerva cardioangiologica
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更新日期：1994-03-01 00:00:00
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journal_title：Minerva cardioangiologica
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更新日期：1995-11-01 00:00:00
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journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
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journal_title：Minerva cardioangiologica
pub_type： 杂志文章
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更新日期：1990-12-01 00:00:00
abstract：:After recalling that cardiovascular complications represent the most frequent cause of mortality and morbidity in hypertensive patients, the author describes the main mechanism responsible for increased plasma level concentrations of Angiotensin in this syndrome. He subsequently illustrates the effects of ACE-inhibito...
journal_title：Minerva cardioangiologica
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journal_title：Minerva cardioangiologica
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doi：
更新日期：1996-04-01 00:00:00
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journal_title：Minerva cardioangiologica
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更新日期：2006-04-01 00:00:00
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journal_title：Minerva cardioangiologica
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doi：10.23736/S0026-4725.18.04703-5
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journal_title：Minerva cardioangiologica
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更新日期：2013-02-01 00:00:00
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journal_title：Minerva cardioangiologica
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更新日期：1991-11-01 00:00:00
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journal_title：Minerva cardioangiologica
pub_type： 杂志文章,评审
doi：
更新日期：2005-10-01 00:00:00
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journal_title：Minerva cardioangiologica
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
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pub_type： 临床试验,杂志文章
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更新日期：2010-10-01 00:00:00
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journal_title：Minerva cardioangiologica
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更新日期：1990-01-01 00:00:00
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更新日期：2016-04-20 00:00:00
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pub_type： 社论
doi：
更新日期：1996-10-01 00:00:00
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journal_title：Minerva cardioangiologica
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doi：
更新日期：1994-04-01 00:00:00
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doi：
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journal_title：Minerva cardioangiologica
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doi：
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journal_title：Minerva cardioangiologica
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journal_title：Minerva cardioangiologica
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doi：
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doi：
更新日期：2000-12-01 00:00:00
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journal_title：Minerva cardioangiologica
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doi：
更新日期：1995-10-01 00:00:00
