当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES期刊下所有文献 > Ficin: A protease extract with relevance in biotechnology and biocatalysis.

Ficin: A protease extract with relevance in biotechnology and biocatalysis.

Abstract：

:Due to the problems raised by the use of animal or microbial recombinant proteases, the use of proteases from vegetable origin is becoming increasingly popular.. Among them, sulfidryl proteases have a special interest. Ficin is an outstanding example of this kind of proteases. This paper aims to be to make a comprehensive review of the recent uses of this enzyme, including for example protein hydrolysis, the production of bioactive peptides and antibodies fragments (researchers point that ficin results are more reproducible than using other proteases), meat tenderization, milk coagulations in cheese making or peptide synthesis. Efforts to get industrial immobilized biocatalysts of the enzyme will be also described. The review shows the huge potential and brilliant prospect that this enzyme can have in the near future.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Morellon-Sterling R,El-Siar H,Tavano OL,Berenguer-Murcia Á,Fernández-Lafuente R

doi

10.1016/j.ijbiomac.2020.06.144

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

394-404

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(20)33584-4

journal_volume

162

pub_type

杂志文章,评审

相关文献

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES文献大全
  • Glycation of α-synuclein amplifies the binding with glyceraldehyde-3-phosphate dehydrogenase.

    abstract：:α-Synuclein was recently found to interact with moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) involved in neurodegenerative diseases development. In the present work, we have analyzed influence of α-synuclein glycation on this interaction, because the literature data suggest relation ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.01.064

    authors： Semenyuk P,Barinova K,Muronetz V

    更新日期：2019-04-15 00:00:00

  • A systematic evaluation of hydroxyethyl starch as a potential nanocarrier for parenteral drug delivery.

    abstract：:Development of parenteral nanoformulations is highly challenging due to the stringent demands on stability, reproducibility and high drug loading with minimal excipients. This study focuses on the development of a pharmaceutically acceptable nanomatrix system for parenteral delivery based on Hydroxyethyl Starch (HES),...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2014.12.012

    authors： Narayanan D,Nair S,Menon D

    更新日期：2015-03-01 00:00:00

  • One pot synthesis of metal ion anchored alginate-gelatin binary biocomposite for efficient Cr(VI) removal.

    abstract：:Biopolymers are widely used for the removal of chromium from aqueous medium but it possesses limitations like poor sorption capacity and low stability. To overcome the limitations of biopolymers and to improve their properties, the present study was designed in such a way to develop a novel sorbent with enhanced chrom...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.10.010

    authors： Gopalakannan V,Viswanathan N

    更新日期：2016-02-01 00:00:00

  • Chemical modification of cellulosic biopolymer and its use in removal of heavy metal ions from wastewater.

    abstract：:Use of biological macromolecules for wastewater remediation process has become the topic of intense research mostly driven by growing concerns about the depletion of petroleum oil reserves and environmental problems. So in view of technological significance of cellulosic biopolymers in various fields, the present stud...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2014.03.046

    authors： Singha AS,Guleria A

    更新日期：2014-06-01 00:00:00

  • Amylopectin-g-poly(methylacrylate-co-sodium acrylate): An efficient Cd(II) binder.

    abstract：:Synthesis, characterization and Cd(II) adsorption studies of a novel biodegradable graft copolymer based on partially hydrolysed polymethylacrylate (PMA) grafted amylopectin was reported, which was prepared by first grafting of PMA chains onto the amylopectin backbone followed by partial alkaline hydrolysis. The hydro...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.06.022

    authors： Sasmal D,Kolya H,Tripathy T

    更新日期：2016-10-01 00:00:00

  • A novel GH16 beta-agarase isolated from a marine bacterium, Microbulbifer sp. BN3 and its characterization and high-level expression in Pichia pastoris.

    abstract：:An agar-degrading bacterium, strain BN3, was isolated from a coastal soil sample collected in Taiwan Strait, China and identified to be a novel species of the genus Microbulbifer. The gene (N3-1) encoding for a novel β-agarase from the isolate was cloned and sequenced. It encoded a mature protein with 274 amino acids ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.08.053

    authors： Li RK,Chen Z,Ying XJ,Ng TB,Ye XY

    更新日期：2018-11-01 00:00:00

  • Alginate/chitosan multilayer films coated on IL-4-loaded TiO2 nanotubes for modulation of macrophage phenotype.

    abstract：:Macrophage phenotype conversion is crucial for improving post-traumatic angiogenesis and tissue repair. Biomaterials with the ability of skewing macrophage phenotype have attracted widespread attention in the field of tissue engineering. The aim of this study was to transform macrophage phenotype by a three-step proce...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.03.184

    authors： Yin X,Li Y,Yang C,Weng J,Wang J,Zhou J,Feng B

    更新日期：2019-07-01 00:00:00

  • Anti-obesity effect and protection of liver-kidney functions by Codium fragile sulphated polysaccharide on high fat diet induced obese rats.

    abstract：:The present study investigates the hypolipidemic effects of sulphated polysaccharide obtained from Codium fragile (CFSP) in induced obese rats (HFD). The results showed an increase in body weight of HFD rats by 21.56% as compared to control normal rats. Moreover, serum lipase activity underwent an increase which led t...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.04.017

    authors： Kolsi RBA,Jardak N,Hajkacem F,Chaaben R,Jribi I,Feki AE,Rebai T,Jamoussi K,Fki L,Belghith H,Belghith K

    更新日期：2017-09-01 00:00:00

  • Natural killer cell-mediated anticancer effects of an arabinogalactan derived from rice hull in CT26 colon cancer-bearing mice.

    abstract：:Rice hull polysaccharides (RHPS) have been reported to activate innate immunity in mice. This study investigated the effects of RHPS on natural killer (NK) cell-mediated cytotoxicity in vitro and the possible underlying anticancer mechanisms in vivo. The results showed that sustained exposure to RHPS increased NK-92MI...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.11.200

    authors： Yang LC,Lai CY,Hsieh CC,Lin WC

    更新日期：2019-03-01 00:00:00

  • A connection between antimicrobial properties of venom peptides and microbial ATP synthase.

    abstract：:Venom peptides anoplin, cupiennin 1a, latarcin 1, latarcin 3a, latarcin 5, melittin, and pandinin 2 are known to have antibacterial properties. In the current study, we examined whether the antimicrobial properties of these venom peptides have any connection to the binding and inhibition of bacterial ATP synthase. Ven...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.07.146

    authors： Syed H,Tauseef M,Ahmad Z

    更新日期：2018-11-01 00:00:00

  • Protective effect of a polysaccharide from Dipsacus asper Wall on streptozotocin (STZ)-induced diabetic nephropathy in rat.

    abstract：:The effects of a polysaccharide (DAP) from the roots of Dipsacus asper on renal complication in streptozotocin (STZ)-induced diabetic rats were investigated in the present study. Administration of DAP (100 and 300 mg/kg) for 4 weeks significantly decreased the fasting blood glucose (FBG) and glycosylated hemoglobin (H...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.04.069

    authors： Li T,Hua Q,Li N,Cui Y,Zhao M

    更新日期：2019-07-15 00:00:00

  • Isolation and characterization of lignocellulose nanofibers from different wheat straw pulps.

    abstract：:Wheat straw was cooked under different pulping processes: Soda (100°C, 7% NaOH, 150min), Kraft (170°C, 16% alkalinity, 25% sulfidity, 40min) and Organosolv (210°C, 60% ethanol, 60min). Once the pulps were obtained, lignocellulose nanofibers (LCNF) were isolated by mechanical process and TEMPO-mediated oxidation follow...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.08.019

    authors： Sánchez R,Espinosa E,Domínguez-Robles J,Loaiza JM,Rodríguez A

    更新日期：2016-11-01 00:00:00

  • Anti-tumor and macrophage activation induced by alkali-extracted polysaccharide from Pleurotus ostreatus.

    abstract：:Pleurotus ostreatus is popularly consumed as traditional medicine and health food for enhancing immune function in China. Polysaccharides from mushroom have been demonstrated to possess a wide range of health beneficial properties. This study was carried out to elucidate the immunomodulating effects and molecular mech...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2014.05.045

    authors： Kong F,Li FE,He Z,Jiang Y,Hao R,Sun X,Tong H

    更新日期：2014-08-01 00:00:00

  • Protective effects of lentinan on lipopolysaccharide induced inflammatory response in intestine of juvenile taimen (Hucho taimen, Pallas).

    abstract：:Antioxidant effects of lentinan on LPS induced inflammatory response in intestine of juvenile taimen were evaluated, and its prebiotic-like efficacy on intestinal microbiota was also investigated. The results showed that LPS decreased the activities of antioxidant enzymes and increased the expression levels of inflamm...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.09.121

    authors： Ren G,Xu L,Lu T,Zhang Y,Wang Y,Yin J

    更新日期：2019-01-01 00:00:00

  • Novel oleyl amine-modified polymannuronic acid micelle loading tacrolimus for therapy of allergic conjunctivitis.

    abstract：:Marine polysaccharide-based nanomaterial attracted considerable attention due to its biocompatibility and biodegradability. Here, a novel polymannuronic acid derivative (PM-C18) was synthesized as nanocarrier modified with hydrophobic oleyl amine. Its structure was confirmed by Fourier-transformed infrared spectrometr...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.06.064

    authors： Cong M,Wu Z,Xu X,Yin J,Li H,Zhuang B,Wang C,Zhao X

    更新日期：2017-11-01 00:00:00

  • Microbial serine protease inhibitors and their therapeutic applications.

    abstract：:Serine protease inhibitors, inhibit serine proteases either partially or completely after forming complexes with their respective proteases. Protease actions are significant for many physiological pathways found in living forms and any anomalies may lead to numerous physiological complications. Each cell or organism h...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijbiomac.2017.09.115

    authors： Harish BS,Uppuluri KB

    更新日期：2018-02-01 00:00:00

  • Chitin and chitosan based polyurethanes: A review of recent advances and prospective biomedical applications.

    abstract：:Chitin and chitosan are amino polysaccharides having massive structural propensities to produce bioactive materials with innovative properties, functions and diverse applications particularly in biomedical field. The specific physico-chemical, mechanical, biological and degradation properties offer efficient way to bl...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijbiomac.2016.02.004

    authors： Usman A,Zia KM,Zuber M,Tabasum S,Rehman S,Zia F

    更新日期：2016-05-01 00:00:00

  • Development of multi-epitope driven subunit vaccine against Fasciola gigantica using immunoinformatics approach.

    abstract：:Fascioliasis, a serious helminth disease of the livestock population, results from infection with the parasite Fasciola. Despite the alarming increase in drug resistance, a safe and fully effective vaccine for fascioliasis is still not available. In the present study, we employed high-throughput immunoinformatics appr...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.07.024

    authors： Kalita P,Lyngdoh DL,Padhi AK,Shukla H,Tripathi T

    更新日期：2019-10-01 00:00:00

  • Bioactive yet antimicrobial structurally stable collagen/chitosan/lysine functionalized hyaluronic acid - based injectable hydrogels for potential bone tissue engineering applications.

    abstract：:Novel, biocompatible, multifunctional, injectable genipin crosslinked collagen/chitosan/lysine-modified hyaluronic acid based hydrogels (ColChHAmod) were prepared in a facile, one-step procedure. The novelty of the current approach lies in the functionalization of hyaluronic acid (HA) with primary amine groups by lysi...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.11.052

    authors： Gilarska A,Lewandowska-Łańcucka J,Guzdek-Zając K,Karewicz A,Horak W,Lach R,Wójcik K,Nowakowska M

    更新日期：2020-07-15 00:00:00

  • Molecular mass and antitumor activities of sulfated derivatives of alpha-glucan from Poria cocos mycelia.

    abstract：:Two kinds of water-insoluble (1-->3)-alpha-D-glucan samples, ab-PCM3-I and ac-PCM3-I, isolated from different Poria cocos mycelia were sulfated, to produce two series of water-soluble derivatives ab-PCM3-I-S1-S5 and ac-PCM3-I-S1-S5, respectively. The derivatives having different weight-average molecular mass (Mw) were...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2004.08.001

    authors： Lin Y,Zhang L,Chen L,Jin Y,Zeng F,Jin J,Wan B,Cheung PC

    更新日期：2004-10-01 00:00:00

  • Mechanical properties improvement of thermoplastic corn starch and polyethylene-grafted-maleicanhydride blending by Na+ ions neutralization of carboxymethyl cellulose.

    abstract：:Corn starch was melt-blended with glycerol (70/30) to prepare thermoplastic starch (TPS) at 140 °C for 10 min. The TPS was melt-blended with polyethylene grafted with maleic anhydride (PE-MAH) and carboxymethyl cellulose (CMC) to improve the properties of the TPS. Phase determination analysis and SEM images demonstrat...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.08.076

    authors： Jantanasakulwong K,Wongsuriyasak S,Rachtanapun P,Seesuriyachan P,Chaiyaso T,Leksawasdi N,Techapun C

    更新日期：2018-12-01 00:00:00

  • The benzene metabolite p-benzoquinone inhibits the catalytic activity of bovine liver catalase: A biophysical study.

    abstract：:The current communication reports the inhibitory effect of para-benzoquinone (p-BQ) on the structure and function of bovine liver catalase (BLC), a vital antioxidant enzyme. Both BLC and p-BQ were dissolved in respective buffers and the biophysical interaction was studied at physiological concentrations. For the first...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.11.044

    authors： Jena AB,Samal RR,Kumari K,Pradhan J,Chainy GBN,Subudhi U,Pal S,Dandapat J

    更新日期：2021-01-15 00:00:00

  • Synthesis of a dextran based thermo-sensitive drug delivery system by gamma irradiation.

    abstract：:Gamma radiation was used as the initiator/crosslinker agent for the synthesis of thermo-sensitive hydrogel networks, under the form of membranes, using dextran and N-isopropylacrylamide. The prepared membranes were loaded with Ondansetron™, a potent antiemetic drug and tested as drug delivery systems. The characteriza...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.07.002

    authors： Almeida JF,Ferreira P,Alves P,Lopes A,Gil MH

    更新日期：2013-10-01 00:00:00

  • Enzymatic collapse of artificial polymer composite material containing double-stranded DNA.

    abstract：:Large amounts of DNA-enriched biomaterials, such as salmon milts and shellfish gonads, are discarded as industrial waste around the world. Therefore, the utilizations of DNA with the specific function are important for the biomaterial science and the curce technology. We could convert the discarded DNA to an enzymatic...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2008.03.005

    authors： Yamada M,Amoo M

    更新日期：2008-06-01 00:00:00

  • Inhibitory effects of β-ionone on amyloid fibril formation of β-lactoglobulin.

    abstract：:β-Lactoglobulin (β-LG) is the major constituent of whey food, which has been shown to interact with a wide range of aroma compounds. In the present work, a model aroma compound, β-ionone, is used to investigate the influence of aroma compounds on the urea-induced unfolding of β-LG at pH 7.0. β-Ionone is observed to en...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.12.003

    authors： Ma B,You X,Lu F

    更新日期：2014-03-01 00:00:00

  • Exploring the effects of methylene blue on amyloid fibrillogenesis of lysozyme.

    abstract：:The 129-residue lysozyme has been shown to form amyloid fibrils in vitro. While methylene blue (MB), a compound in the phenothiazinium family, has been shown to dissemble tau fibril formation, its anti-fibrillogenic effect has not been thoroughly characterized in other proteins/peptides. This study examines the effect...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.08.038

    authors： How SC,Cheng YH,Lo CH,Lai JT,Lin TH,Bednarikova Z,Antosova A,Gazova Z,Wu JW,Wang SS

    更新日期：2018-11-01 00:00:00

  • Improvement in physical and biological properties of chitosan/soy protein films by surface grafted heparin.

    abstract：:A series of chitosan/soy protein isolate (SPI) composite films (CS-n, n=0, 10 and 30, corresponding to SPI content in the composites) were prepared. Heparin was grafted onto the surface of CS-n to fabricate a series of heparinized films (HCS-n). CS-n and HCS-n were characterized by ATR-Fourier transform infrared spect...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.11.052

    authors： Wang X,Hu L,Li C,Gan L,He M,He X,Tian W,Li M,Xu L,Li Y,Chen Y

    更新日期：2016-02-01 00:00:00

  • Effect of sea buckthorn protein on the intestinal microbial community in streptozotocin-induced diabetic mice.

    abstract：:This study investigated the intestinal microbial community distribution of Type 2 diabetic mice and discussed the effects of the sea buckthorn protein on the regulation of gut microbes. Date was collected for 12 cases of normal mice (NC group), 12 cases of Type 2 diabetic mice (DC group), and 12 cases of highly concen...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.09.090

    authors： Yuan H,Shi F,Meng L,Wang W

    更新日期：2018-02-01 00:00:00

  • Preparation of Thai silk fibroin/gelatin electrospun fiber mats for controlled release applications.

    abstract：:This work studied the effect of preparation conditions for electrospun fiber mats of Thai silk fibroin/type B gelatin (SF/GB) for controlled release applications. The increasing in applied voltage resulted in decreased average fiber size and narrow fiber size distribution. An increasing in silk fibroin content in blen...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2010.02.008

    authors： Okhawilai M,Rangkupan R,Kanokpanont S,Damrongsakkul S

    更新日期：2010-06-01 00:00:00

  • Use of glyoxyl-agarose immobilized ficin extract in milk coagulation: Unexpected importance of the ficin loading on the biocatalysts.

    abstract：:A protein extract obtained from fig tree (Ficus carica) latex containing ficin activity was immobilized on glyoxyl agarose. Different biocatalyst loadings were used (3, 10, 30 and 85 mg/g). When casein was used as substrate, the expressed activities were 60%, 58%, 41% and 14%, respectively, very likely due to casein d...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.12.140

    authors： Siar EH,Morellon-Sterling R,Zidoune MN,Fernandez-Lafuente R

    更新日期：2020-02-01 00:00:00