Abstract:
INTRODUCTION:Iliopsoas muscle hemorrhage in patients with hemophilia is a serious complication with relevant related morbidity. AREAS COVERED:A Cochrane Library and PubMed (MEDLINE) search of studies related to iliopsoas hematomas in hemophilia was analyzed. Pain in the hip joint area and femoral nerve involvement in people with hemophilia should alert physicians to the likelihood of a hemorrhage of the iliopsoas muscle. Clinically, reduced hip range of motion and deficient motor and sensory function of the femoral nerve can be found. Imaging studies, such as ultrasonography (US), CT scan, and MRI will confirm the diagnosis. The first-line therapy for iliopsoas hematoma must be conservative (hematological treatment using high-dose replacement therapy until full resorption monitored by means of imaging studies). Related femoral nerve involvement typically resolves with conservative treatment (rehabilitation). Pelvic hemophilic pseudotumors can occur in patients with hemophilia due to recurrent iliopsoas muscle bleeding, often related to late diagnosis and poor hemostasis. EXPERT OPINION:Long-term clotting factor replacement is the pillar of the management of iliopsoas hematomas. Percutaneous US-guided aspiration of blood can be performed in hematomas of large size. However, the rate of failed aspirations and hematoma repetition is substantial (13%).
journal_name
Expert Rev Hematoljournal_title
Expert review of hematologyauthors
Rodriguez-Merchan EC,De la Corte-Rodriguez Hdoi
10.1080/17474086.2020.1787146subject
Has Abstractpub_date
2020-08-01 00:00:00pages
803-809issue
8eissn
1747-4086issn
1747-4094journal_volume
13pub_type
杂志文章abstract::Asparaginase has been a mainstay of therapy in the treatment of acute lymphoblastic leukemia since the 1970s. There are two major preparations available and FDA approved in the United States today, one derived from Escherichia coli and the other from Erwinia chrysanthemi. Erwinia asparaginase is antigenically distinct...
journal_title:Expert review of hematology
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journal_title:Expert review of hematology
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journal_title:Expert review of hematology
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journal_title:Expert review of hematology
pub_type: 杂志文章,评审
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journal_title:Expert review of hematology
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journal_title:Expert review of hematology
pub_type: 杂志文章,评审
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更新日期:2011-04-01 00:00:00
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journal_title:Expert review of hematology
pub_type: 杂志文章,评审
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更新日期:2016-07-01 00:00:00
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journal_title:Expert review of hematology
pub_type: 杂志文章,评审
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更新日期:2015-04-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-10-01 00:00:00
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journal_title:Expert review of hematology
pub_type: 杂志文章,评审
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更新日期:2014-06-01 00:00:00
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journal_title:Expert review of hematology
pub_type: 杂志文章,评审
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更新日期:2017-11-01 00:00:00
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journal_title:Expert review of hematology
pub_type: 杂志文章,评审
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更新日期:2008-12-01 00:00:00
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journal_title:Expert review of hematology
pub_type: 杂志文章,评审
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更新日期:2014-02-01 00:00:00
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journal_title:Expert review of hematology
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更新日期:2013-06-01 00:00:00
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更新日期:2010-12-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,meta分析,评审
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pub_type: 杂志文章
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更新日期:2020-06-01 00:00:00
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journal_title:Expert review of hematology
pub_type: 杂志文章,meta分析,评审
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更新日期:2018-11-01 00:00:00
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journal_title:Expert review of hematology
pub_type: 杂志文章,评审
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更新日期:2013-08-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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