Abstract:
PURPOSE:To review the incidence, aetiology and outcomes of endophthalmitis during a 20-year period in a Norwegian university hospital. METHODS:Single-centre retrospective review. Medical records of all patients admitted to Stavanger University Hospital with suspected endophthalmitis between January 1999 and December 2018 were reviewed. RESULTS:We identified 84 eyes of 81 patients. Postoperative endophthalmitis (PE) was seen in 64 eyes (76%), endogenous endophthalmitis in thirteen eyes (15%), trauma in four eyes (5%) and three eyes (4%) had keratitis-associated endophthalmitis. Administration of intravitreal injections (IVI) was the most common cause (30%), followed by cataract surgery (CS) (21%). Of 40238 IVI, 23 PE cases were identified (incidence, 0.057%; 95% confidence interval [CI] 0.036-0.086%). Of 39697 CS, 12 PE cases were identified (incidence, 0.030%; 95%CI 0.016-0.053%). After introduction of intracameral cefuroxime PE incidence after CS decreased from 0.10% in 1999-2003 to 0.015% in 2004-2018 (p = 0.003). Eighty-four per cent of organisms were Gram-positive. Coagulase-negative staphylococci accounted for 54% of culture-proven cases, and 89% of post-IVI culture-proven cases. Thirty eyes (36%) either regained their previous vision or lost ≤1 Early Treatment Diabetic Retinopathy Study line. One third of endophthalmitis cases had a favourable visual outcome of logMAR 0.2 or better. CONCLUSION:PE after IVI occurred in 1 in 1750 procedures, and was the most common cause of PE. The incidence of PE after CS has decreased >sixfold since 2003, to 1 in 6700 surgeries. A high proportion of low-virulence bacterial species may have contributed to the favourable visual outcome.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Malmin A,Syre H,Ushakova A,Utheim TP,Forsaa VAdoi
10.1111/aos.14511subject
Has Abstractpub_date
2020-06-22 00:00:00eissn
1755-375Xissn
1755-3768pub_type
杂志文章abstract:PURPOSE:To evaluate the ability of ultrasound biomicroscopy (UBM) to detect abnormalities in the zonular apparatus in unaffected eyes of patients with clinically unilateral exfoliation syndrome (XFS) using a standardized grading system. METHODS:The affected and unaffected eyes of 17 patients with clinically unilateral...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1600-0420.2007.01105.x
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:To determine change in visual acuity (VA) in the population of a previous amblyopia treatment study (Loudon 2006) and assess risk factors for VA decrease. METHODS:Subjects treated between 2001 and 2003 were contacted between December 2015 and July 2017. Orthoptic examination was conducted under controlled circ...
journal_title:Acta ophthalmologica
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abstract::Ziv-aflibercept (Zaltrap® ), a recombinant fusion protein that binds diffusible vascular endothelial growth factor (VEGF), is approved for the treatment of metastatic colorectal carcinoma. Its molecular structure is the same as aflibercept (Eylea® ), thus making it an attractive option for the off-label treatment of c...
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更新日期:2019-12-20 00:00:00
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doi:10.1111/aos.12609
更新日期:2015-06-01 00:00:00
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更新日期:2018-11-01 00:00:00
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doi:10.1111/j.1755-3768.2012.02494.x
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12105
更新日期:2014-05-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2014-05-01 00:00:00
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journal_title:Acta ophthalmologica
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更新日期:2015-03-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2014-06-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2013-11-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2018-06-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
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更新日期:2018-05-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2012.02456.x
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pub_type: 杂志文章
doi:10.1111/aos.14700
更新日期:2020-12-16 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2016-09-01 00:00:00
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pub_type: 杂志文章
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2008.01305.x
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1755-3768.2008.01313.x
更新日期:2009-02-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01812.x
更新日期:2011-12-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0420.2007.01068.x
更新日期:2008-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-05-01 00:00:00
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更新日期:2021-01-09 00:00:00
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更新日期:2017-12-01 00:00:00
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更新日期:2017-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2010-08-01 00:00:00