Analysis of Breast Cancer Patients with T1-2 Tumors and 1-3 Positive Lymph Nodes Treated with or without Postmastectomy Radiation Therapy.

abstract：:Epithelial-mesenchymal transition (EMT) plays an important role in tumor invasion and metastasis. A comprehensive, bioinformatics analysis of CCLE and TCGA datasets of seven tumor types allowed us to identify a novel pan-cancer EMT-associated gene expression signature consisting of 16 epithelial and 4 mesenchymal stat...

journal_title：Scientific reports

authors： Rokavec M,Kaller M,Horst D,Hermeking H

更新日期：2017-07-05 00:00:00

abstract：:The southeastern Mediterranean Sea (SEMS) is a warm and sunlit marine environment with low ambient N concentration, thus considered ideal for diazotrophy by autotrophic diazotrophs such as Trichodesmium. Despite the favorable conditions, N2 fixation rates are often low and Trichodesmium has hardly been spotted in the ...

journal_title：Scientific reports

authors： Rahav E,Bar-Zeev E

更新日期：2017-06-29 00:00:00

abstract：:Gene set enrichment analysis (GSEA) associates gene sets and phenotypes, its use is predicated on the choice of a pre-defined collection of sets. The defacto standard implementation of GSEA provides seven collections yet there are no guidelines for the choice of collections and the impact of such choice, if any, is un...

journal_title：Scientific reports

authors： Bateman AR,El-Hachem N,Beck AH,Aerts HJ,Haibe-Kains B

更新日期：2014-02-13 00:00:00

abstract：:Most glioblastoma patients have a dismal prognosis, although some survive several years. However, only few biomarkers are available to predict the disease course. EGR1 and EGR3 have been linked to glioblastoma stemness and tumour progression, and this study aimed to investigate their spatial expression and prognostic ...

journal_title：Scientific reports

authors： Knudsen AM,Eilertsen I,Kielland S,Pedersen MW,Sørensen MD,Dahlrot RH,Boldt HB,Munthe S,Poulsen FR,Kristensen BW

更新日期：2020-06-09 00:00:00

abstract：:Assessing and managing the impact of large-scale epidemics considering only the individual risk and severity of the disease is exceedingly difficult and could be extremely expensive. Economic consequences, infrastructure and service disruption, as well as the recovery speed, are just a few of the many dimensions along...

journal_title：Scientific reports

authors： Massaro E,Ganin A,Perra N,Linkov I,Vespignani A

更新日期：2018-01-30 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Xu J,Roy A,Palli SR

更新日期：2018-08-02 00:00:00

abstract：:A frequency reconfigurable dipole antenna based on a silicon radiator is presented. The silicon radiator is activated with the aid of highly dense solid-state plasma by injecting carriers into the intrinsic region of p-i-n diodes. The fabrication and design guideline of the reconfigurable dipole antenna with this plas...

journal_title：Scientific reports

authors： Kim DJ,Jo ES,Cho YK,Hur J,Kim CK,Kim CH,Park B,Kim D,Choi YK

更新日期：2018-10-09 00:00:00

abstract：:The Tcf/Lef family of transcription factors mediates the Wnt/β-catenin pathway that is involved in a wide range of biological processes, including vertebrate embryogenesis and diverse pathogenesis. Post-translational modifications, including phosphorylation, sumoylation and acetylation, are known to be important for t...

journal_title：Scientific reports

authors： Han W,Lee H,Han JK

更新日期：2017-02-15 00:00:00

abstract：:This study was aimed to assess the relationship of intraocular forward scattering, corneal backward scattering, and corneal higher-order aberrations (HOAs) with corrected distance visual acuity (CDVA) in eyes with granular corneal dystrophy (GCD). We retrospectively examined forty two eyes of 42 consecutive patients w...

journal_title：Scientific reports

authors： Kamiya K,Kobashi H,Igarashi A,Shoji N,Shimizu K

更新日期：2016-04-18 00:00:00

abstract：:The relative effects of internal fixation strategies for intertrochanteric fracture after operation remain uncertain. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to address this important issue. We searched PubMed, EMBASE and CENTRAL for RCTs that compared different intern...

journal_title：Scientific reports

authors： Yu J,Zhang C,Li L,Kwong JS,Xue L,Zeng X,Tang L,Li Y,Sun X

更新日期：2015-12-11 00:00:00

abstract：:Despite the initiative by WHO and other international organizations to eliminate HCV in the medium term, hepatitis C infection is still a major public health problem. Even non-injecting drugs users who engage in harmful or addictive drug use are at greater risk of acquiring the infection, when compared to the general ...

journal_title：Scientific reports

authors： Coutinho C,Bastos LS,da Mota JC,Toledo L,Costa K,Bertoni N,Bastos FI

更新日期：2019-01-24 00:00:00

abstract：:According to the Source Monitoring Framework, the origin of a memory is remembered through the retrieval of specific features (e.g. perceptive, sensitive, affective signals). In two source discrimination tasks, we studied the ability of cuttlefish to remember the modality in which an item had been presented several ho...

journal_title：Scientific reports

authors： Billard P,Clayton NS,Jozet-Alves C

更新日期：2020-03-25 00:00:00

abstract：:CIC-DUX4 sarcoma (CDS) is a group of rare, mesenchymal, small round cell tumours that harbour the unique CIC-DUX4 translocation, which causes aberrant gene expression. CDS exhibits an aggressive course and poor clinical outcome, thus novel therapeutic approaches are needed for CDS treatment. Although patient-derived c...

journal_title：Scientific reports

authors： Oyama R,Takahashi M,Yoshida A,Sakumoto M,Takai Y,Kito F,Shiozawa K,Qiao Z,Arai Y,Shibata T,Araki Y,Endo M,Kawai A,Kondo T

更新日期：2017-07-05 00:00:00

abstract：:Measurement-based quantum computing is one of the most promising quantum computing models. Although various universal resource states have been proposed so far, it was open whether only two Pauli bases are enough for both of universal measurement-based quantum computing and its verification. In this paper, we construc...

journal_title：Scientific reports

authors： Takeuchi Y,Morimae T,Hayashi M

更新日期：2019-09-19 00:00:00

abstract：:Olfactory receptors are believed to play a central role in insects host-seeking, mating, and ovipositing. On the basis of male and female antennal transcriptome of adult Apolygus lucorum, a total of 110 candidate A. lucorum odorant receptors (AlucOR) were identified in this study including five previously annotated Al...

journal_title：Scientific reports

authors： An XK,Sun L,Liu HW,Liu DF,Ding YX,Li LM,Zhang YJ,Guo YY

更新日期：2016-11-28 00:00:00

abstract：:Acute leukemia (AL) patients undergoing intensive induction chemotherapy develop severe gut dysbiosis, placing them at heightened risk for infectious complications. Some AL patients will undergo "repeat therapy" (re-induction or salvage) due to persistent or relapsed disease. We hypothesized that prior injury to the m...

journal_title：Scientific reports

authors： Rashidi A,Kaiser T,Shields-Cutler R,Graiziger C,Holtan SG,Rehman TU,Wasko J,Weisdorf DJ,Dunny G,Khoruts A,Staley C

更新日期：2019-04-15 00:00:00

abstract：:Stylopine is a protoberberine-type alkaloid that has potential biological activities. Based on the successful microbial production of (S)-reticuline, we attempted to produce stylopine from (S)-reticuline by the reaction of berberine bridge enzyme, cheilanthifoline synthase (CYP719A5), and stylopine synthase (CYP719A2)...

journal_title：Scientific reports

authors： Hori K,Okano S,Sato F

更新日期：2016-02-29 00:00:00

abstract：:Based on the electrical characteristic detection technology, the quantitative prediction models of sensory score and physical and chemical quality Index (theaflavins, thearubigins, and theabrownins) were established by using the fermented products of Congou black tea as the research object. The variation law of electr...

journal_title：Scientific reports

authors： Dong C,An T,Zhu H,Wang J,Hu B,Jiang Y,Yang Y,Li J

更新日期：2020-01-31 00:00:00

abstract：:Hyperdisulfide-constrained peptides are distinguished by their high stability and diverse functions. Thus far, these peptides have been reported from animals only but their occurrence in plants are rare. Here, we report the discovery, synthesis and characterization of a hyperdisulfide-constrained peptides family of ap...

journal_title：Scientific reports

authors： Wong KH,Tan WL,Xiao T,Tam JP

更新日期：2017-07-21 00:00:00

abstract：:Carcinomas constitute over 80% of all human cancer types with no effective therapy for metastatic disease. Here, we demonstrate, for the first time, the efficacy of therapeutic-ultrasound (TUS) to deliver a human tumor suppressor gene, hSef-b, to prostate tumors in vivo. Sef is downregulated in various human carcinoma...

journal_title：Scientific reports

authors： Mishel S,Shneyer B,Korsensky L,Goldshmidt-Tran O,Haber T,Machluf M,Ron D

更新日期：2017-11-08 00:00:00

abstract：:Ooids are typically spherical sediment grains characterised by concentric layers encapsulating a core. There is no universally accepted explanation for ooid genesis, though factors such as agitation, abiotic and/or microbial mineralisation and size limitation have been variously invoked. Here we examine the possible i...

journal_title：Scientific reports

authors： Batchelor MT,Burne RV,Henry BI,Li F,Paul J

更新日期：2018-01-11 00:00:00

abstract：:Recent studies have revealed the systematic altering of gene expression in human peripheral blood during the early stages of ischemic stroke, which suggests a new potential approach for the rapid diagnosis or prediction of stroke onset. Nevertheless, due to the difficulties of collecting human samples during proper di...

journal_title：Scientific reports

authors： Wang Y,Cai Y

更新日期：2016-07-13 00:00:00

abstract：:WD40 proteins belong to a big protein family with members identified in every eukaryotic proteome. However, WD40 proteins were only reported in a few prokaryotic proteomes. Using WDSP ( http://wu.scbb.pkusz.edu.cn/wdsp/ ), a prediction tool, we identified thousands of prokaryotic WD40 proteins, among which few protein...

journal_title：Scientific reports

authors： Shen C,Du Y,Qiao F,Kong T,Yuan L,Zhang D,Wu X,Li D,Wu YD

更新日期：2018-08-28 00:00:00

abstract：:Parent selection is the core of hybrid breeding. The breeding strategy involving the parental identification of superior open-pollinated progeny of Populous tomentosa germplasm resources can significantly improve the efficiency of parental matching. However, due to some factors such as loose powdering time and pollen ...

journal_title：Scientific reports

authors： Han Z,Han Q,Xia Y,Geng X,Du K,Yang J,Kang X

更新日期：2020-10-29 00:00:00

abstract：:Fibrates, which are widely used lipidaemic-modulating drugs, are emerging environmental pollutants. However, fibrate concentrations in the environment have not been thoroughly surveyed. Here, we determined concentrations of the most commonly used fibrates and their metabolites in source water and drinking water sample...

journal_title：Scientific reports

authors： Ido A,Hiromori Y,Meng L,Usuda H,Nagase H,Yang M,Hu J,Nakanishi T

更新日期：2017-04-12 00:00:00

abstract：:Understanding and control of heat dissipation is an important challenge in nanoelectronics wherein field-accelerated hot carriers in current-carrying ballistic systems release a large part of the kinetic energy into external bulk phonon baths. Here we report on a physical mechanism of this remote heat dissipation and ...

journal_title：Scientific reports

authors： Tsutsui M,Morikawa T,Yokota K,Taniguchi M

更新日期：2018-05-18 00:00:00

abstract：:In this paper, we investigate the high frequency performance of Co90Zr10/SiO2/Co90Zr10 trilayers. It is demonstrated that the in-plane isotropic microwave performance is theoretically derived from the solution of the Landau-Lifshitz-Gilbert equation and experimentally achieved in that sandwich structured film. The val...

journal_title：Scientific reports

authors： Pan L,Wang F,Wang W,Chai G,Xue D

更新日期：2016-02-17 00:00:00

abstract：:Under specific reaction conditions, levansucrase from Bacillus subtilis (SacB) catalyzes the synthesis of a low molecular weight levan through the non-processive elongation of a great number of intermediates. To deepen understanding of the polymer elongation mechanism, we conducted a meticulous examination of the fruc...

journal_title：Scientific reports

authors： Raga-Carbajal E,López-Munguía A,Alvarez L,Olvera C

更新日期：2018-10-09 00:00:00

abstract：:Maximal rate of heart rate (HR) increase (rHRI) as a measure of HR acceleration during the transition from rest to exercise, or during an increase in workload, tracks exercise performance. rHRI assessed at relative rather than absolute workloads may track performance better, and a field test would increase applicabili...

journal_title：Scientific reports

authors： Bellenger CR,Thomson RL,Robertson EY,Davison K,Nelson MJ,Karavirta L,Buckley JD

更新日期：2020-09-03 00:00:00

abstract：:Flavonoids, due to their pharmacological attributes, have recently become target molecules for metabolic engineering in commonly consumed food crops. Strategies including expression of single genes and gene pyramiding have provided only limited success, due principally to the highly branched and complex biosynthetic p...

journal_title：Scientific reports

authors： Pandey A,Misra P,Bhambhani S,Bhatia C,Trivedi PK

更新日期：2014-05-21 00:00:00