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Distinctiveness of prolonged-grief-disorder- and depressive-symptom trajectories in the first 2 years of bereavement for family caregivers of terminally ill cancer patients.

Abstract：

OBJECTIVE:Grief reactions in bereaved caregivers of cancer patients have been identified individually as distinct prolonged grief disorder (PGD)-and major depressive disorder (MDD)-symptom trajectories, but no research has examined whether the patterns of change (trajectories) for PGD and MDD symptoms synchronize during bereavement. We conducted a secondary analysis study to investigate the construct distinctiveness of PGD and MDD by simultaneously identifying and examining similarities and differences between bereaved caregivers' PGD- and depressive-symptom trajectories from immediately post-loss through 2 years later. METHODS:PGD and depressive symptoms were measured for 849 cancer patients' caregivers over their first 2 years of bereavement using 11 grief-symptom items of the prolonged grief-13 scale (PG-11) and the center for epidemiologic studies-depression (CES-D) scale, respectively. PGD- and depressive-symptom trajectories were identified using latent class growth analysis with continuous latent-class indicators (total PG-11 and CES-D scores). Concordance of caregiver participants' membership in PGD- and depressive-symptom trajectories was examined by a percentage and a kappa value. RESULTS:Five distinct symptom trajectories were identified for both PGD and MDD, with four shared trajectories (endurance, transient-reaction, resilience, and prolonged-symptomatic) having different prevalence rankings. Nonetheless, unique trajectories were identified for PGD (potential recurrence) and depressive symptoms (chronically distressed), respectively. Concordance between membership in PGD- and depressive-symptom trajectories was moderate (61.3%, kappa [95% CI]: 0.49 [0.44, 0.53]). CONCLUSION:PGD and MDD are related but distinct constructs indicated by the unique trajectories identified for each, different prevalence rankings for PGD- and depressive-symptom trajectories, and moderate concordance between membership in PGD- and depressive-symptom trajectories, respectively.

journal_name

Psychooncology

journal_title

Psycho-oncology

authors

Wen FH,Chou WC,Shen WC,Tang ST

doi

10.1002/pon.5441

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

1524-1532

issue

eissn

1057-9249

issn

1099-1611

journal_volume

pub_type

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Distinctiveness of prolonged-grief-disorder- and depressive-symptom trajectories in the first 2 years of bereavement for family caregivers of terminally ill cancer patients.