Complicated skin and soft tissue infections in remote indigenous communities.

abstract：:Individualised drug dosing has been shown to improve patient outcomes and reduce adverse drug events. One method of individualised medicine is the Bayesian approach, which uses prior information about how the population responds to therapy, to inform clinicians about how a specific individual is responding to their cu...

journal_title：Internal medicine journal

authors： Donagher J,Martin JH,Barras MA

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:High concentration oxygen is commonly administered during acute exacerbations of chronic obstructive pulmonary disease (AECOPD). The aim of this study was to determine the association between oxygen, severity markers and poor outcomes in AECOPD. METHODS:In an audit of patients with AECOPD arriving by ambula...

journal_title：Internal medicine journal

authors： Wijesinghe M,Perrin K,Healy B,Hart K,Clay J,Weatherall M,Beasley R

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:There are several treatment modalities available for diabetes; however, the effects of the different medications on coronary artery disease are less understood. The purpose of this study was to evaluate the correlation of insulin-sensitizing therapy with the outcome of stress myocardial perfusion testing and...

journal_title：Internal medicine journal

authors： Kapinya K,Nijjar PS,Stanek M,Amanullah A

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Myelodysplastic syndrome (MDS), a haematological disorder of the elderly, has been formally classified as a neoplastic disease for 10 years. AIMS:Our aim was to collate national cancer registry incidence data to describe the epidemiology of MDS in New Zealand. METHODS:The New Zealand Cancer Registry has no...

journal_title：Internal medicine journal

authors： Rodger EJ,Morison IM

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Exacerbations requiring hospital admission for chronic obstructive pulmonary disease (COPD) contribute to a decline in health status and are costly to the community. Long-term trends in admissions and associated outcomes are difficult to establish because of frequent readmissions, high case fatality and pote...

journal_title：Internal medicine journal

authors： Geelhoed EA,Brameld KJ,Holman CD,Thompson PJ

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Low dose computed tomography (LDCT) screening can reduce lung cancer deaths in high risk individuals yet current Australian guidelines do not recommend screening. Little is known about current screening practices in Australia. METHODS:A survey was distributed to a nationally-representative sample of 4000 Au...

journal_title：Internal medicine journal

authors： Abeyweera PD,Brims FJH,Piccolo F,Lei C,Manners D

更新日期：2020-04-01 00:00:00

abstract：:The Australian National Chronic Obstructive Pulmonary Disease (COPD) guidelines recommend that inhaled corticosteroids (ICS) be reserved for patients with a post-bronchodilator forced expiratory volume in 1 s (FEV1 ) less than 50% predicted and those who experience ≥2 exacerbations in 12 months. In total, 707 COPD pat...

journal_title：Internal medicine journal

authors： Harrison A,Borg B,Thompson B,Hew M,Dabscheck E

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND/AIM:This study aimed to report the clinical characteristics and outcomes of Australian patients treated with eculizumab for atypical haemolytic uraemic syndrome (aHUS). METHODS:A retrospective cohort study was undertaken of all patients in Australia treated with eculizumab provided in a compassionate access...

journal_title：Internal medicine journal

authors： Mallett A,Hughes P,Szer J,Tuckfield A,Van Eps C,Cambell SB,Hawley C,Burke J,Kausman J,Hewitt I,Parnham A,Ford S,Isbel N

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Despite the frequency of cannula-associated Staphylococcus aureus bacteraemia (CASAB) there is uncertainty regarding the duration of treatment required. AIM:To determine the relationship between the duration and type of treatment for CASAB and subsequent relapse with deep-seated S. aureus infection. METHOD...

journal_title：Internal medicine journal

authors： Thomas MG,Morris AJ

更新日期：2005-06-01 00:00:00

abstract：:Growth hormone (GH) replacement therapy was recently recommended by the Pharmaceutical Benefits Advisory Committee (PBAC) for listing on the Pharmaceutical Benefits Scheme for adults with severe GH deficiency and impaired quality of life. This approval was significant for two reasons. First, the application was initia...

journal_title：Internal medicine journal

authors： Lipworth W,Ambler G,Burt MG,Fairchild J,Inder WJ,Werther G,Ho K

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis (EoE) is a newly recognised condition that is apparently increasing in prevalence, and the aetiology is poorly understood. The role of aeroallergens in EoE is controversial, given the success of dietary therapy. Massive aeroallergen exposure leading to food bolus obstruction events (...

journal_title：Internal medicine journal

authors： Philpott HL,Nandurkar S,Thien F,Bloom S,Lin E,Goldberg R,Boyapati R,Finch A,Royce SG,Gibson PR

更新日期：2015-09-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) haplogroups are 'neutral polymorphisms' in the mtDNA genome, which have accumulated and persisted along maternal lineages as the human population has migrated worldwide. Three ethnically distinct lineages of human mtDNA populations have been identified: European, characterized by nine haplogr...

journal_title：Internal medicine journal

authors： Manwaring N,Jones MM,Wang JJ,Rochtchina E,Mitchell P,Sue CM

更新日期：2006-08-01 00:00:00

abstract：:There is evidence of the increasing use of complementary and alternative medicine by Australians diagnosed with cancer. Given the increasing desire of cancer patients to use complementary and alternative medicine, it is important that clinicians have a good understanding of the evidence available in this field. This c...

journal_title：Internal medicine journal

authors： Joske DJ,Rao A,Kristjanson L

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND/AIM:Few studies have specifically investigated treatment of prednisolone-induced hyperglycaemia. AIM:To determine if a basal bolus insulin (BBI) protocol for inpatient hyperglycaemia is effective in patients prescribed acute prednisolone for an inflammatory disease. METHODS:In a cross-sectional study, 66 p...

journal_title：Internal medicine journal

authors： Burt MG,Drake SM,Aguilar-Loza NR,Esterman A,Stranks SN,Roberts GW

更新日期：2015-03-01 00:00:00

abstract：:The use of tissue-type plasminogen activator (t-PA) in ischaemic stroke outside of experienced stroke centres remains controversial. The aim of this study was to present the initial experience with t-PA in patients with ischaemic stroke at an institution with no prior experience in i.v. stroke thrombolysis and to comp...

journal_title：Internal medicine journal

authors： Bray JE,Coughlan K,Bladin C

更新日期：2006-08-01 00:00:00

abstract：:Ambulatory care is an important service for patients with the COVID-19 infection especially in a regional area where most of the patients underwent home isolation. Escalation of treatment and timely transition to inpatient care are critical when COVID-19 patients deteriorate. Equally important is ensuring transfer int...

journal_title：Internal medicine journal

authors： Lwin N,Burgess J,Johnston C,Johnson N,Chung S

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Since Hinton first published his observations on the distress of patients dying on a medical ward in 1963, there has been increasing awareness of the palliative care needs in patients who have non malignant diseases. Patients with advanced chronic obstructive pulmonary disease (COPD) are known to have compar...

journal_title：Internal medicine journal

authors： Iupati SP,Ensor BR

更新日期：2016-03-01 00:00:00

abstract：AIMS:We sought to assess a broad array of possible precipitants of acute coronary syndromes (ACS) and evaluate their association with detectable inflammatory activation. METHODS AND RESULTS:Within a case-crossover design, using a standardised questionnaire, interviews among 348 ST-elevation myocardial infarction (44%)...

journal_title：Internal medicine journal

authors： Chew DP,Mattschoss S,Horsfall M,Astley C,Vaile JC,Joseph MX

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Both low-molecular-weight heparin (LMWH) and unfractionated heparin (UFH) have been shown to be equivalent in efficacy and safety profiles for the management of pulmonary embolism (PE). AIMS:To assess the real world management of anticoagulation in PE in a tertiary hospital setting. METHODS:An audit of pat...

journal_title：Internal medicine journal

authors： Khor YH,Smith R,McDonald CF

更新日期：2014-04-01 00:00:00

abstract：:More than 177 000 potentially preventable healthcare-associated infections (HAIs) occur per annum in Australia with sizable attributable mortality. Organizational systems to protect against HAI in hospitals in Australia are relatively poorly developed. Awareness and practice of infection control by medical and other h...

journal_title：Internal medicine journal

authors： Ferguson JK

更新日期：2009-09-01 00:00:00

abstract：:An acute pulmonary embolism (aPE) is characterised by occlusion of one or more pulmonary arteries. Physiological disturbance may be minimal, but often cardiac output decreases as the right ventricle attempts to overcome increased afterload. Additionally, ventilation-perfusion mismatches can develop in affected vascula...

journal_title：Internal medicine journal

authors： Hepburn-Brown M,Darvall J,Hammerschlag G

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The reported risk of depression in patients with hypomagnesaemia is controversial. AIM:The objective of this meta-analysis was to assess the association between depression and hypomagnesaemia. METHODS:A literature search was performed using MEDLINE, EMBASE, Cochrane Database and clinicaltrials.gov from inc...

journal_title：Internal medicine journal

authors： Cheungpasitporn W,Thongprayoon C,Mao MA,Srivali N,Ungprasert P,Varothai N,Sanguankeo A,Kittanamongkolchai W,Erickson SB

更新日期：2015-04-01 00:00:00

abstract：:The purpose of this case-control study is to estimate the risks of Stevens-Johnson syndrome or toxic epidermal necrolysis associated with the use of specific drugs. The suspected cases were identified from the computerized hospital discharge file. We calculated crude relative risks and adjusted them for confounding by...

journal_title：Internal medicine journal

authors： Lin MS,Dai YS,Pwu RF,Chen YH,Chang NC

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The clinical significance of extreme hyperferritinaemia has come under scrutiny with the increasing recognition of haemophagocytic lymphohistiocytosis (HLH) in adults. Most studies of hyperferritinaemia have focused on serum ferritin greater than 1000 μg/L, often in ambulatory patients. The conditions associ...

journal_title：Internal medicine journal

authors： Wormsbecker AJ,Sweet DD,Mann SL,Wang SY,Pudek MR,Chen LY

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Infections and antibiotic resistance patterns in patients attending regional Australian cancer centres are poorly described. AIMS:To document patient characteristics, infection types, patterns of antibiotic resistance and outcomes in all patients with cancer requiring inpatient management for suspected infe...

journal_title：Internal medicine journal

authors： De Silva N,Jackson J,Steer C

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:There is little existing research on the role that secondary care letters have in ensuring patient understanding of chronic health conditions. AIM:To determine whether minimising the use of medical terminology in medical correspondence improved patient understanding and anxiety/depression scores. METHODS:A...

journal_title：Internal medicine journal

authors： Wernick M,Hale P,Anticich N,Busch S,Merriman L,King B,Pegg T

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Our previous work identified deficiencies in stroke care practices at regional hospitals in comparison to standards suggested by published stroke care guidelines. These deficiencies might be improved by the implementation of clinical pathways. The aim of this study was to assess changes in acute stroke care ...

journal_title：Internal medicine journal

authors： Read SJ,Levy J

更新日期：2006-10-01 00:00:00

abstract：:In this essay, I reflect on my experience as a multiple sclerosis patient in order to identify some of the unique challenges that chronic disability poses in the physician-patient relationship. I suggest that it is important to broaden the goals of the clinical encounter to incorporate personal (as opposed to simply b...

journal_title：Internal medicine journal

authors： Toombs SK

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Many patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have type 2 respiratory failure (T2RF). Often arterial blood gases are not performed and correlation with venous blood gases (VBG) is controversial. The venous pH and bicarbonate (HCO3 ) are useful, but VBG pCO2 (PvCO2 )...

journal_title：Internal medicine journal

authors： Wong EKC,Lee PCS,Ansary S,Asha S,Wong KKH,Yee BJ,Ng AT

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Chronic lymphocytic leukaemia (CLL) frequently responds to chemoimmunotherapy combining cytotoxic chemotherapy and monoclonal antibodies. However, CLL is associated with significant genetic heterogeneity, and some high-risk forms are known to be chemo-resistant and associated with early relapse. AIMS:To rev...

journal_title：Internal medicine journal

authors： Kuss BJ,Tam CS

更新日期：2017-12-01 00:00:00