Complete chloroplast genome sequence of Barleria prionitis, comparative chloroplast genomics and phylogenetic relationships among Acanthoideae.

abstract：BACKGROUND:Stress responses provide valuable models for deciphering the transcriptional networks controlling the adaptation of the cell to its environment. We analyzed the transcriptome response of yeast to toxic concentrations of selenite. We used gene network mapping tools to identify functional pathways and transcri...

journal_title：BMC genomics

authors： Salin H,Fardeau V,Piccini E,Lelandais G,Tanty V,Lemoine S,Jacq C,Devaux F

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:Escherichia coli infections known as colibacillosis constitute a considerable challenge to poultry farmers worldwide, in terms of decreased animal welfare and production economy. Colibacillosis is caused by avian pathogenic E. coli (APEC). APEC strains are extraintestinal pathogenic E. coli and have in gener...

journal_title：BMC genomics

authors： Ronco T,Stegger M,Olsen RH,Sekse C,Nordstoga AB,Pohjanvirta T,Lilje B,Lyhs U,Andersen PS,Pedersen K

更新日期：2017-01-03 00:00:00

abstract：BACKGROUND:Studies of gene regulation often utilize genome-wide predictions of transcription factor (TF) binding sites. Most existing prediction methods are based on sequence information alone, ignoring biological contexts such as developmental stages and tissue types. Experimental methods to study in vivo binding, inc...

journal_title：BMC genomics

authors： Zhong S,He X,Bar-Joseph Z

更新日期：2013-11-15 00:00:00

abstract：BACKGROUND:Fusarium graminearum virus 1 strain-DK21 (FgV1-DK21) is a mycovirus that confers hypovirulence to F. graminearum, which is the primary phytopathogenic fungus that causes Fusarium head blight (FHB) disease in many cereals. Understanding the interaction between mycoviruses and plant pathogenic fungi is necessa...

journal_title：BMC genomics

authors： Cho WK,Yu J,Lee KM,Son M,Min K,Lee YW,Kim KH

更新日期：2012-05-06 00:00:00

abstract：BACKGROUND:Precise identification of three-dimensional genome organization, especially enhancer-promoter interactions (EPIs), is important to deciphering gene regulation, cell differentiation and disease mechanisms. Currently, it is a challenging task to distinguish true interactions from other nearby non-interacting o...

journal_title：BMC genomics

authors： Zeng W,Wu M,Jiang R

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:Inadvertent sample swaps are a real threat to data quality in any medium to large scale omics studies. While matches between samples from the same individual can in principle be identified from a few well characterized single nucleotide polymorphisms (SNPs), omics data types often only provide low to moderat...

journal_title：BMC genomics

authors： Westphal M,Frankhouser D,Sonzone C,Shields PG,Yan P,Bundschuh R

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:During cancer progression, malignant cells accumulate somatic mutations that can lead to genetic aberrations. In particular, evolutionary events akin to segmental duplications or deletions can alter the copy-number profile (CNP) of a set of genes in a genome. Our aim is to compute the evolutionary distance b...

journal_title：BMC genomics

authors： Cordonnier G,Lafond M

更新日期：2020-04-16 00:00:00

abstract：BACKGROUND:Copy number variations (CNVs) are a major form of genetic variations and are involved in animal domestication and genetic adaptation to local environments. We investigated CNVs in the domestic goat (Capra hircus) using Illumina short-read sequencing data, by comparing our lab data for 38 goats from three Chi...

journal_title：BMC genomics

authors： Guo J,Zhong J,Liu GE,Yang L,Li L,Chen G,Song T,Zhang H

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:NOD26-like intrinsic proteins (NIPs) that belong to the aquaporin superfamily are plant-specific and exhibit a similar three-dimensional structure. Experimental evidences however revealed that functional divergence should have extensively occurred among NIP genes. It is therefore intriguing to further invest...

journal_title：BMC genomics

authors： Liu Q,Wang H,Zhang Z,Wu J,Feng Y,Zhu Z

更新日期：2009-07-15 00:00:00

abstract：BACKGROUND:Gene expression analysis by reverse transcription quantitative PCR (qPCR) is the most widely used method for analyzing the expression of a moderate number of genes and also for the validation of microarray results. Several issues are crucial for a successful qPCR study, particularly the selection of internal...

journal_title：BMC genomics

authors： Robledo D,Hernández-Urcera J,Cal RM,Pardo BG,Sánchez L,Martínez P,Viñas A

更新日期：2014-08-04 00:00:00

abstract：BACKGROUND:Bacterial vaginosis (BV) is an ecological disorder of the vaginal microbiota that affects millions of women annually, and is associated with numerous adverse health outcomes including pre-term birth and the acquisition of sexually transmitted infections. However, little is known about the overall structure a...

journal_title：BMC genomics

authors： Ling Z,Kong J,Liu F,Zhu H,Chen X,Wang Y,Li L,Nelson KE,Xia Y,Xiang C

更新日期：2010-09-07 00:00:00

abstract：BACKGROUND:The genome-wide association (GWA) approach represents an alternative to biparental linkage mapping for determining the genetic basis of trait variation. Both approaches rely on recombination to re-arrange the genome, and seek to establish correlations between phenotype and genotype. The major advantages of G...

journal_title：BMC genomics

authors： Cericola F,Portis E,Lanteri S,Toppino L,Barchi L,Acciarri N,Pulcini L,Sala T,Rotino GL

更新日期：2014-10-14 00:00:00

abstract：MOTIVATION:Deciphering gene interaction networks (GINs) from time-course gene expression (TCGx) data is highly valuable to understand gene behaviors (e.g., activation, inhibition, time-lagged causality) at the system level. Existing methods usually use a global or local proximity measure to infer GINs from a single dat...

journal_title：BMC genomics

authors： Liu Q,Song R,Li J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:As economically relevant traits, feeding behavior and food preference domestication determine production cost and profitability. Although there are intensive research efforts on feeding behavior and food intake, little is known about food preference. Mandarin fish accept only live prey fish and refuse dead p...

journal_title：BMC genomics

authors： He S,Liang XF,Sun J,Li L,Yu Y,Huang W,Qu CM,Cao L,Bai XL,Tao YX

更新日期：2013-09-05 00:00:00

abstract：BACKGROUND:Screening for differentially expressed genes on the genomic scale and comparative analysis of the expression profiles of orthologous genes between species to study gene function and regulation are becoming increasingly feasible. Expressed sequence tags (ESTs) are an excellent source of data for such studies ...

journal_title：BMC genomics

authors： Pao SY,Lin WL,Hwang MJ

更新日期：2006-04-21 00:00:00

abstract：BACKGROUND:Soybean seed weight is not only a yield component, but also a critical trait for various soybean food products such as sprouts, edamame, soy nuts, natto and miso. Linkage analysis and genome-wide association study (GWAS) are two complementary and powerful tools to connect phenotypic differences to the underl...

journal_title：BMC genomics

authors： Yan L,Hofmann N,Li S,Ferreira ME,Song B,Jiang G,Ren S,Quigley C,Fickus E,Cregan P,Song Q

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:An important subfamily of membrane proteins are the transmembrane alpha-helical proteins, in which the membrane-spanning regions are made up of alpha-helices. Given the obvious biological and medical significance of these proteins, it is of tremendous practical importance to identify the location of transmem...

journal_title：BMC genomics

authors： Yang JY,Yang MQ,Dunker AK,Deng Y,Huang X

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Crohn's disease (CD) is an inflammatory bowel disease caused by genetic and environmental factors. More than 160 susceptibility loci have been identified for IBD, yet a large part of the genetic variance remains unexplained. Recent studies have demonstrated genetic differences between monozygotic twins, who ...

journal_title：BMC genomics

authors： Petersen BS,Spehlmann ME,Raedler A,Stade B,Thomsen I,Rabionet R,Rosenstiel P,Schreiber S,Franke A

更新日期：2014-07-05 00:00:00

abstract：BACKGROUND:Bifidobacteria are commonly found as part of the microbiota of the gastrointestinal tract (GIT) of a broad range of hosts, where their presence is positively correlated with the host's health status. In this study, we assessed the genomes of thirteen representatives of Bifidobacterium breve, which is not onl...

journal_title：BMC genomics

authors： Bottacini F,O'Connell Motherway M,Kuczynski J,O'Connell KJ,Serafini F,Duranti S,Milani C,Turroni F,Lugli GA,Zomer A,Zhurina D,Riedel C,Ventura M,van Sinderen D

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Oceans cover more than 70% of the earth's surface and are critical for the homeostasis of the environment. Among the components of the ocean ecosystem, zooplankton play vital roles in energy and matter transfer through the system. Despite their importance, understanding of zooplankton biodiversity is limited...

journal_title：BMC genomics

authors： Machida RJ,Hashiguchi Y,Nishida M,Nishida S

更新日期：2009-09-17 00:00:00

abstract：BACKGROUND:Mapping DNaseI hypersensitive sites is commonly used to identify regulatory regions in the genome. However, currently available methods are either time consuming and laborious, expensive or require large numbers of cells. We aimed to develop a quick and straightforward method for the analysis of DNaseI hyper...

journal_title：BMC genomics

authors： Ohnesorg T,Eggers S,Leonhard WN,Sinclair AH,White SJ

更新日期：2009-09-04 00:00:00

abstract：BACKGROUND:Sugarcane (Saccharum spp.) has become an increasingly important crop for its leading role in biofuel production. The high sugar content species S. officinarum is an octoploid without known diploid or tetraploid progenitors. Commercial sugarcane cultivars are hybrids between S. officinarum and wild species S....

journal_title：BMC genomics

authors： Wang J,Roe B,Macmil S,Yu Q,Murray JE,Tang H,Chen C,Najar F,Wiley G,Bowers J,Van Sluys MA,Rokhsar DS,Hudson ME,Moose SP,Paterson AH,Ming R

更新日期：2010-04-23 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) regulate the expression of target genes by mediating gene silencing in both plants and animals. The miRNA targets have been extensively investigated in Arabidopsis and rice using computational prediction, experimental validation by overexpression in transgenic plants, and by degradome or P...

journal_title：BMC genomics

authors： Shamimuzzaman M,Vodkin L

更新日期：2012-07-16 00:00:00

abstract：BACKGROUND:Identification of acute or recent hepatitis C virus (HCV) infections is important for detecting outbreaks and devising timely public health interventions for interruption of transmission. Epidemiological investigations and chemistry-based laboratory tests are 2 main approaches that are available for identifi...

journal_title：BMC genomics

authors： Lara J,Teka M,Khudyakov Y

更新日期：2017-12-06 00:00:00

abstract：BACKGROUND:Palmitoylation is a reversible post-translational protein modification which involves the addition of palmitate to cysteine residues. Palmitoylation is catalysed by the DHHC family of palmitoyl-acyl transferases (PATs) and reversibility is conferred by palmitoyl-protein thioesterases (PPTs). Mutations in gen...

journal_title：BMC genomics

authors： Edmonds MJ,Morgan A

更新日期：2014-10-02 00:00:00

abstract：BACKGROUND:Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal storage disorder characterized by severe neurologic and ophthalmologic abnormalities. Recently the MLIV gene, MCOLN1, has been identified as a new member of the transient receptor potential (TRP) cation channel superfamily. Here we report the c...

journal_title：BMC genomics

authors： Falardeau JL,Kennedy JC,Acierno JS Jr,Sun M,Stahl S,Goldin E,Slaugenhaupt SA

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that human populations have experienced a complex demographic history, including a recent epoch of rapid population growth that led to an excess in the proportion of rare genetic variants in humans today. This excess can impact the burden of private mutations for each individual, de...

journal_title：BMC genomics

authors： Gao F,Keinan A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The ability to identify regions of the genome inherited with a dominant trait in one or more families has become increasingly valuable with the wide availability of high throughput sequencing technology. While a number of methods exist for mapping of homozygous variants segregating with recessive traits in c...

journal_title：BMC genomics

authors： Levine AP,Connor TM,Oygar DD,Neild GH,Segal AW,Maxwell PH,Gale DP

更新日期：2015-03-10 00:00:00

abstract：BACKGROUND:Health traits are of significant economic importance to the dairy industry due to their effects on milk production and associated treatment costs. Genome-wide association studies (GWAS) provide a means to identify associated genomic variants and thus reveal insights into the genetic architecture of complex t...

journal_title：BMC genomics

authors： Freebern E,Santos DJA,Fang L,Jiang J,Parker Gaddis KL,Liu GE,VanRaden PM,Maltecca C,Cole JB,Ma L

更新日期：2020-01-13 00:00:00

abstract：BACKGROUND:The nutritional value of soybean oil is largely influenced by the proportions of unsaturated fatty acids (FAs), including oleic acid (OA, 18:1), linoleic acid (LLA, 18:2), and linolenic acid (LNA, 18:3). Genome-wide association (GWAS) studies along with gene expression studies in soybean [Glycine max (L.) Me...

journal_title：BMC genomics

authors： Zhao X,Jiang H,Feng L,Qu Y,Teng W,Qiu L,Zheng H,Han Y,Li W

更新日期：2019-01-21 00:00:00