Abstract:
:Cerebral venous thrombosis (CVT) is an uncommon cause of stroke that mainly affects young adults with known risk factors of prothrombotic conditions, pregnancy, infection, malignancy, and drugs. Dutasteride is a 5α-reductase inhibitor that is used for benign prostate hypertrophy and androgenetic alopecia. To date, CVT caused by dutasteride use has not been reported. A 25-year-old male presented with headache and diplopia. He had taken 0.5 mg of dutasteride every other day for 9 months to treat alopecia. A headache developed 7 months after he started taking medication, and horizontal diplopia occurred 1 month after the onset of headache. Fundus examination showed bilateral papilledema. Brain magnetic resonance imaging showed thrombosis in the left sigmoid and transverse sinuses. Headache and diplopia improved after discontinuing dutasteride and starting anticoagulation. The results from this case report indicated dutasteride as a potential cause of CVT. Presumably, the increased estrogen level due to dutasteride use caused the formation of a thrombus.
journal_name
Yonsei Med Jjournal_title
Yonsei medical journalauthors
Choi BK,Cheon K,Cho BH,Jung JW,Lee KYdoi
10.3349/ymj.2020.61.6.553subject
Has Abstractpub_date
2020-06-01 00:00:00pages
553-555issue
6eissn
0513-5796issn
1976-2437pii
61.553journal_volume
61pub_type
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