Improved Outcomes after Reperfusion Therapies for Ischemic Stroke: A "Real-world" Study in a Developing Country.

abstract：:Diabetes is associated with deficits in memory and cognitive functions and sustained inflammation. Recently, involvement of NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) has been postulated in many cognitive functions, immune system and inflammation. Despite of role of NF-κB in inflammation, a...

journal_title：Current neurovascular research

authors： Datusalia AK,Sharma SS

更新日期：2016-01-01 00:00:00

abstract：:Disruption of the blood-spinal cord barrier (BSCB) and microvascular changes leading to reduction of blood supply represent hallmarks of spinal cord secondary injury causing further deterioration of the traumatized patient. Injury to the blood vessels starts with prominent hemorrhage and generation of inflammation. Fu...

journal_title：Current neurovascular research

authors： Graumann U,Ritz MF,Hausmann O

更新日期：2011-11-01 00:00:00

abstract：:No longer considered exclusive for the function of the hematopoietic system, erythropoietin (EPO) is now considered as a viable agent to address central nervous system injury in a variety of cellular systems that involve neuronal, vascular, and inflammatory cells. Yet, it remains unclear whether the protective capacit...

journal_title：Current neurovascular research

authors： Chong ZZ,Li F,Maiese K

更新日期：2005-12-01 00:00:00

abstract：:In multiple sclerosis (MS) plaques are known to be venocentric; in addition, MS lesions and peripheral venous disorders share a number of key features. To date, however, despite the anatomical relationship between MS lesions and the venous system, no information on the intracranial venous haemodynamics of MS is availa...

journal_title：Current neurovascular research

authors： Zamboni P,Menegatti E,Bartolomei I,Galeotti R,Malagoni AM,Tacconi G,Salvi F

更新日期：2007-11-01 00:00:00

abstract：:Ununited peripheral nerves represent attractive site for connectivity with neuroprostheses because their predictable internal topography allows precise sorting of motor and sensory signals. Also transplantation of bone marrow mesenchymal stem cells (BMSCs) is increasingly recognized as an effective method of restore t...

journal_title：Current neurovascular research

authors： Wu W,Zhang S,Chen Y,Liu H

更新日期：2017-01-01 00:00:00

abstract：:Pericytes are perivascular cells and have heterogenous roles in the brain, such as controlling blood flow and entry of immune cells or regulating the blood-brain barrier. Platelet-derived growth factor (PDGF) receptor-beta (PDGFRβ) is highly expressed in pericytes, representing the most selective biomarker. The aim of...

journal_title：Current neurovascular research

authors： Hutter-Schmid B,Humpel C

更新日期：2016-01-01 00:00:00

abstract：:This study examined whether six days recombinant human growth hormone (rhGH) affected psychological profile in an abstinent androgenic-anabolic steroid (AAS) abusing group, compared with an abstinent AAS control group. Male subjects (n = 48) were assigned in a random fashion into one of two groups: (1): (n=24) control...

journal_title：Current neurovascular research

authors： Graham MR,Davies B,Kicman A,Cowan D,Hullin D,Baker JS

更新日期：2007-02-01 00:00:00

abstract：:Antiendothelial cell antibodies (AECAs) have been detected in patients who have autoimmune and inflammatory diseases. Previous studies showed that AECAs against human umbilical vein endothelial cells were detected in healthy subjects. In the present study, we evaluated AECAs against human brain microvascular endotheli...

journal_title：Current neurovascular research

authors： Kimura A,Sakurai T,Yoshikura N,Koumura A,Hayashi Y,Ohtaki H,Chousa M,Seishima M,Inuzuka T

更新日期：2015-01-01 00:00:00

abstract：:This review demonstrated that ischemic brain injury induces chronic changes in blood-brain barrier in the gray and white matter. This insufficiency of blood-brain barrier may allow entry of uncellular blood components such as different fragments of amyloid precursor protein and cellular blood components like leukocyte...

journal_title：Current neurovascular research

authors： Pluta R

更新日期：2007-05-01 00:00:00

abstract：:In multicellular organisms, apoptosis, also known as programmed cell death, is an important physiological response to eliminate unnecessary, excess, or harmful cells. Apoptosis occurs during embryonic development and is important in maintaining homeostasis during adulthood. Apoptosis also plays critical roles in angio...

journal_title：Current neurovascular research

authors： Sakamaki K

更新日期：2004-10-01 00:00:00

abstract：:HspB5/alphaB-crystallin (alphaBC), one of the most representative member of mammalian small heat shock protein family (sHsp), shares the common features with other nine members HspB1-B4 and HspB6-10. Meanwhile, it has a strong antiapoptic effect; its interaction with cytoskeleton participates in maintaining cell struc...

journal_title：Current neurovascular research

authors： Hu Z,Li T

更新日期：2008-05-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDA-Rs) activation has been implicated in various forms of synaptic plasticity depending on the receptor subtypes involved. However, the contribution of NR2A and NR2B subunits in glycine-induced long-term potentiation (LTP) of miniature excitatory postsynaptic currents (mEPSCs) in laye...

journal_title：Current neurovascular research

authors： Li YH,Wang J

更新日期：2013-02-01 00:00:00

abstract：:The use of cell-based therapy may be a valid therapeutic approach to ischemic brain injury. Stem cells have been proposed as a new form of cell based therapy in a variety of disorders, including acute and degenerative brain diseases. Up to date most efforts have concentrated on transplantation of embryonic stem cells ...

journal_title：Current neurovascular research

authors： Leker RR,McKay RD

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Iron homeostasis disorder and neuroinflammation are the most commonly known factors that promote the occurrence and development of cognitive impairment in people. Dexmedetomidine has an anti-inflammatory effect, and it reduces the incidence of postoperative cognitive dysfunction. Therefore, the aim of this s...

journal_title：Current neurovascular research

authors： Guo F,Kang J,Tan J,Wang Y,Jia L,Xu H

更新日期：2020-01-01 00:00:00

abstract：:Hematopoietic stem cells (HSCs) have long been defined as a cell with the capacity to repopulate the hematopoietic system of a lethally irradiated host. In clinical medicine, this property has been employed to reconstitute an individual's diseased hematopoietic system following ablation with a healthy, normal-function...

journal_title：Current neurovascular research

authors： Chan RJ,Yoder MC

更新日期：2004-07-01 00:00:00

abstract：:In preterm infants, neurological signs and clinical manifestations of brain damage are limited criteria for diagnosis of neurologic sequelae. Early indicators of brain damage are needed and currently some specific biochemical markers of brain injury are investigated to assess regional brain damage after perinatal asph...

journal_title：Current neurovascular research

authors： Giuseppe D,Sergio C,Pasqua B,Giovanni LV,Salvatore C,Frigiola A,Petra H,Maurizio A

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Whether preoperative midline shift and its growing rate are associated with outcomes of decompressive craniectomy in patients with malignant middle cerebral artery infarction is unknown. METHODS:We retrospectively included patients: 1) who underwent decompressive craniectomy for malignant middle cerebral ar...

journal_title：Current neurovascular research

authors： Yuan R,Wu S,Cheng Y,Ye K,Hao Z,Zhang S,Liu Y,Liu M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Dynamin-related protein 1 (DRP1) is a GTPase involved in mitochondrial fission, mitochondrial protein import, and drug sensitivity, suggesting an association with cancer progression. This study was conducted to evaluate the prognostic significance of DRP1 in glioblastoma multiforme (GBM). METHODS:DRP1 expre...

journal_title：Current neurovascular research

authors： Cheng WY,Chow KC,Chiao MT,Yang YC,Shen CC

更新日期：2020-01-01 00:00:00

abstract：:Brain edema following stroke is a critical clinical problem due to its association with increased morbidity and mortality. Despite its significance, present treatment for brain edema simply provides symptomatic relief due to the fact that molecular mechanisms underlying brain edema remain poorly understood. The presen...

journal_title：Current neurovascular research

authors： Higashida T,Peng C,Li J,Dornbos D 3rd,Teng K,Li X,Kinni H,Guthikonda M,Ding Y

更新日期：2011-02-01 00:00:00

abstract：:Increased homocysteine (Hcy) levels contribute to a variety of cardiovascular and cerebrovascular diseases including stroke and Alzheimer's disease. Recent data has shown that elevated levels of Hcy can lead to the blood-brain barrier (BBB) dysfunction and activation. However, the mechanism for Hcy-mediated dysfunctio...

journal_title：Current neurovascular research

authors： Hohsfield LA,Humpel C

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Lacunes and white matter hyperintensities (WMH) are two common findings seen on neuroimaging in patients with cerebral small vessel disease (cSVD). Clinically we observed that some patients with cSVD have aphasia through the language assessment scale. Our study aimed to explore the underlying risk factors fo...

journal_title：Current neurovascular research

authors： Xin J,Huang X,Pan X,Lin L,Sun M,Liu C,Ye Q

更新日期：2019-01-01 00:00:00

abstract：:A stress response consisting of elevated levels of cortisol and catecholamines is common after acute stroke. The plasma levels of natriuretic peptides are known to be elevated after ischemic stroke, but the relations of these neurohormonal systems in the acute phase of stroke and their impact on long-term prognosis ha...

journal_title：Current neurovascular research

authors： Anne M,Juha K,Timo M,Mikko T,Olli V,Kyösti S,Heikki H,Vilho M

更新日期：2007-08-01 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by extracellular beta-amyloid plaques and intracellular tau tangles. AD-related pathology is often accompanied by vascular changes. The predominant vascular lesions in AD are cerebral amyloid angiopathy (CAA) and arteriosclerosis. Platelets circulate along the vessel wall resp...

journal_title：Current neurovascular research

authors： Kniewallner KM,Ehrlich D,Kiefer A,Marksteiner J,Humpel C

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Gait impairment after stroke is considered as a loss of cerebral function but is also the result of dysfunctional cerebral signals travelling to the spinal motor centres. A therapeutic option to restore disturbed cerebral network activity is deep brain stimulation (DBS). METHODS:A promising target for neuro...

journal_title：Current neurovascular research

authors： Bohr A,Schuhmann MK,Papp L,Volkmann J,Fluri F

更新日期：2020-12-01 00:00:00

abstract：:Physiologic functioning of the cerebrovenous system is indispensable for maintaining normal brain function. However, in contrast to the cerebroarterial system, the cerebral venous return is not routinely investigated. Combined high-resolution echo-colour-Doppler (ECD) and transcranial colour coded Doppler sonography (...

journal_title：Current neurovascular research

authors： Menegatti E,Zamboni P

更新日期：2008-11-01 00:00:00

abstract：:Oxaliplatin is a widely used chemotherapeutic agent that induces both acute and chronic peripheral neuropathy. Based on previous research indicating that estrogen replacement may attenuate some forms of pain in ovariectomized animals, we examined the effects of 17β-estradiol in OXAIPN. We discovered that local cold ex...

journal_title：Current neurovascular research

authors： Pan Y,Chen F,Huang S,Cai Z,Lan H,Tong Y,Yu X,Zhao G

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The most valid model for vascular cognitive impairment (VCI) is the mouse bilateral common carotid artery stenosis (BCAS), whose behavioral outcomes are supposedly affected by the remote ischemic conditioning (RIC) through the induction of autophgy. We hope to determine whether RIC contributes to the neuropr...

journal_title：Current neurovascular research

authors： Wang H,Zhang Q,Xu Y,Bian H,Si C,Yan Z,Zhu M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Intracranial aneurysms (IAs) are life-threatening lesions known within the literature to be found incidentally during routine angiographic workup for carotid artery stenosis (CAS). As IAs are associated with vascular shear stress, it is reasonable to expect that altered flow demands within the anterior circu...

journal_title：Current neurovascular research

authors： Rosenbaum MD,Heiferman DM,Raslan OA,Martin B,Dominguez JF,de la Peña PM,Ashley WW,Rosenblum JD,Germanwala AV

更新日期：2019-01-01 00:00:00

abstract：:This study was aimed to evaluate and compare the effect of chronic hypoxia and aging in the oxidative status of brain vessels and synaptosomes. For this purpose we isolated brain vessels and synaptosomes from 3- and 12-month-old rats subjected to chronic hypoxia (10% O₂ for 7 days) or normoxia (21% O₂). Several parame...

journal_title：Current neurovascular research

authors： Carvalho C,Santos MS,Baldeiras I,Oliveira CR,Seiça R,Moreira PI

更新日期：2010-11-01 00:00:00

abstract：:Angiogenesis is associated with improved neurologic recovery after cerebral ischemia. Human bone marrow mesenchymal stem cells (hMSCs) have been successfully used to treat ischemic stroke and were shown to induce the expression of a number of neurotrophic factors including VEGF, epidermal growth factor (EGF) and basic...

journal_title：Current neurovascular research

authors： Ma XL,Liu KD,Li FC,Jiang XM,Jiang L,Li HL

更新日期：2013-05-01 00:00:00