Coronavirus Disease-2019 in Heart Transplant Recipients in Southeastern Michigan: A Case Series.

Abstract:

BACKGROUND:Since coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China, in December 2019, the number of cases has risen exponentially. Clinical characteristics and outcomes among patients with orthotopic heart transplant (OHT) with COVID-19 remain poorly described. METHODS:We performed a retrospective case series of patients with OHT with COVID-19 admitted to 1 of 2 hospitals in Southeastern Michigan between March 21 and April 22, 2020. Clinical data were obtained through review of the electronic medical record. Final date of follow-up was May 7, 2020. Demographic, clinical, laboratory, radiologic, treatment, and mortality data were collected and analyzed. RESULTS:We identified 13 patients with OHT admitted with COVID-19. The mean age of patients was 61 ± 12 years, 100% were black males, and symptoms began 6 ± 4 days before admission. The most common symptoms included subjective fever (92%), shortness of breath (85%), and cough (77%). Six patients (46%) required admission to the intensive care unit. Two patients (15%) died during hospitalization. CONCLUSIONS:Black men may be at increased risk for COVID-19 among patients with OHT. Presenting signs and symptoms in this cohort are similar to those in the general population. Elevated inflammatory markers on presentation appear to be associated with more severe illness.

journal_name

J Card Fail

authors

Ketcham SW,Adie SK,Malliett A,Abdul-Aziz AA,Bitar A,Grafton G,Konerman MC

doi

10.1016/j.cardfail.2020.05.008

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

457-461

issue

6

eissn

1071-9164

issn

1532-8414

pii

S1071-9164(20)30415-2

journal_volume

26

pub_type

杂志文章
  • Acute heart failure with and without concomitant acute coronary syndromes: patient characteristics, management, and survival.

    abstract:BACKGROUND:Acute coronary syndromes (ACS) may precipitate up to a third of acute heart failure (AHF) cases. We assessed the characteristics, initial management, and survival of AHF patients with (ACS-AHF) and without (nACS-AHF) concomitant ACS. METHODS AND RESULTS:Data from 620 AHF patients were analyzed in a prospect...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.cardfail.2014.07.008

    authors: Tarvasmäki T,Harjola VP,Nieminen MS,Siirilä-Waris K,Tolonen J,Tolppanen H,Lassus J,FINN-AKVA Study Group.

    更新日期:2014-10-01 00:00:00

  • HFSA 2006 Comprehensive Heart Failure Practice Guideline.

    abstract::Heart failure (HF) is a syndrome characterized by high mortality, frequent hospitalization, reduced quality of life, and a complex therapeutic regimen. Knowledge about HF is accumulating so rapidly that individual clinicians may be unable to readily and adequately synthesize new information into effective strategies o...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.cardfail.2005.11.005

    authors: Heart Failure Society Of America

    更新日期:2006-02-01 00:00:00

  • Left ventricular remodeling and myocardial recovery on mechanical circulatory support.

    abstract:BACKGROUND:Myocardial recovery after ventricular assist devices (VAD) is rare but appears more common in nonischemic cardiomyopathies (NICM). We sought to evaluate left ventricular (LV) end diastolic diameter (LVEDD) for predicting recovery after VAD. METHODS AND RESULTS:NICM patients receiving long-term mechanical su...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2009.10.018

    authors: Simon MA,Primack BA,Teuteberg J,Kormos RL,Bermudez C,Toyoda Y,Shah H,Gorcsan J 3rd,McNamara DM

    更新日期:2010-02-01 00:00:00

  • Removal from the "waiting list" for heart transplantation: a risk factor for sudden death?

    abstract:METHODS AND RESULTS:Over an 18-month period, the patients on the heart transplantation waiting list at our institution were evaluated to determine if continued listing was appropriate. Ten patients were removed because of significant improvement in clinical status and exercise capacity (n = 9) or because of criteria vi...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/s1071-9164(97)90042-7

    authors: Leier CV,Whitby G,Kennedy RA,Binkley PF

    更新日期:1997-06-01 00:00:00

  • Peak oxygen consumption and outcome in heart failure patients chronically treated with beta-blockers.

    abstract:BACKGROUND:Peak oxygen consumption (VO(2)) is an important criterion for listing patients for cardiac transplantation. Beta-blockers improve survival without affecting peak VO(2). We questioned the value of peak VO(2) in predicting outcome in patients treated with beta-blockers. METHODS AND RESULTS:We reviewed the rec...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/s1071-9164(03)00593-1

    authors: Shakar SF,Lowes BD,Lindenfeld J,Zolty R,Simon M,Robertson AD,Bristow MR,Wolfel EE

    更新日期:2004-02-01 00:00:00

  • Improvement of guideline β-blocker prescribing in heart failure: a cluster-randomized pragmatic trial of a pharmacy intervention.

    abstract:BACKGROUND:Treatment with specific beta-blockers and doses recommended by guidelines is often not achieved in practice. We evaluated an intervention directed to the pharmacy to improve prescribing. METHODS AND RESULTS:We conducted a pragmatic cluster-randomized trial, where facilities (n = 12) with patients (n = 220) ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.cardfail.2013.06.004

    authors: McCarren M,Furmaga E,Jackevicius CA,Sahay A,Coppler TL,Katzianer J,Griffiths RL,Tonnu-Mihara I,Heidenreich P

    更新日期:2013-08-01 00:00:00

  • Alterations of alpha-adrenergic modulations of coronary microvascular tone in dogs with heart failure.

    abstract:BACKGROUND:It remains unclear whether coronary microvascular response to alpha-adrenergic activation alters in chronic heart failure (CHF). METHODS AND RESULTS:We investigated the alpha-adrenergic receptor-mediated effects on coronary pressure-flow relationship (CPFR) in a tachycardia-induced canine heart failure mode...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2005.01.003

    authors: Tamagawa K,Saito T,Oikawa Y,Maehara K,Yaoita H,Maruyama Y

    更新日期:2005-06-01 00:00:00

  • Sympathetic nervous system function as measured by I-123 metaiodobenzylguanidine predicts transplant-free survival in heart failure patients with idiopathic dilated cardiomyopathy.

    abstract:BACKGROUND:Heightened activity of the sympathetic nervous system in heart failure patients is a major contributor to disease progression and death. I-123 metaiodobenzylguanidine (MIBG) provides an accurate, noninvasive method to assess cardiac sympathetic nerve activity. METHODS:Thirty-seven patients with New York Hea...

    journal_title:Journal of cardiac failure

    pub_type: 临床试验,杂志文章

    doi:10.1054/s1071-9164(03)00134-9

    authors: Gerson MC,McGuire N,Wagoner LE

    更新日期:2003-10-01 00:00:00

  • γ-Glutamyltransferase rather than total bilirubin predicts outcome in chronic heart failure.

    abstract:BACKGROUND:Gamma-glutamyltransferase (GGT) and total bilirubin (T-Bil) are elevated and of prognostic significance in chronic heart failure (CHF). This study sought to compare these novel cardiovascular risk markers in CHF. METHODS AND RESULTS:We evaluated 1,087 ambulatory patients from our heart failure program. Long...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2011.02.012

    authors: Ess M,Mussner-Seeber C,Mariacher S,Lorsbach-Koehler A,Pachinger O,Frick M,Ulmer H,Poelzl G

    更新日期:2011-07-01 00:00:00

  • Muscle cell grafting for the treatment and prevention of heart failure.

    abstract:BACKGROUND:The review aims to highlight recent advances in cardiac and skeletal muscle cell grafting for myocardial infarct repair. RESULTS:Fetal and neonatal cardiomyocytes form new myocardium in normal or injured hearts, and this new myocardium differentiates toward an adult phenotype. Unfortunately, formation of ne...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,评审

    doi:10.1054/jcaf.2002.129268

    authors: Murry CE,Whitney ML,Reinecke H

    更新日期:2002-12-01 00:00:00

  • Regional variations in physicians' attitudes and recommendations surrounding implantable cardioverter-defibrillators.

    abstract:INTRODUCTION:This study was designed to determine if physicians' attitudes and recommendations surrounding implantable cardioverter-defibrillators (ICDs) are regionally associated with ICD use. METHODS AND RESULTS:A national sample of 9969 members of the American College of Cardiology was surveyed electronically. Resp...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2010.11.009

    authors: Matlock DD,Kutner JS,Emsermann CB,Al-Khatib SM,Sanders GD,Dickinson LM,Rumsfeld JS,Davidson AJ,Crane LA,Masoudi FA

    更新日期:2011-04-01 00:00:00

  • Decreased heart rate recovery after exercise in patients with congestive heart failure: effect of beta-blocker therapy.

    abstract:BACKGROUND:Decreased heart rate recovery (HRR) is a predictor of mortality in patients with coronary artery disease and preserved left ventricular function. We investigated the changes in HRR and assessed the impact of beta-blockade therapy on these parameters in patients with symptomatic congestive heart failure (CHF)...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1054/jcaf.2003.47

    authors: Racine N,Blanchet M,Ducharme A,Marquis J,Boucher JM,Juneau M,White M

    更新日期:2003-08-01 00:00:00

  • A synthetic non-degradable polyethylene glycol hydrogel retards adverse post-infarct left ventricular remodeling.

    abstract:BACKGROUND:Left ventricular remodeling after myocardial infarction is a key component of heart failure and it has long been postulated that it may result from increased wall stress. It has recently been suggested that an injectable, non-degradable polymer may limit pathological remodeling in a manner analogous to that ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2009.03.003

    authors: Dobner S,Bezuidenhout D,Govender P,Zilla P,Davies N

    更新日期:2009-09-01 00:00:00

  • Plasma MMP-9 and MMP-2 following acute myocardial infarction in man: correlation with echocardiographic and neurohumoral parameters of left ventricular dysfunction.

    abstract:BACKGROUND:Left ventricular dilatation and elevated plasma natriuretic peptide levels predict adverse prognosis and the development of congestive heart failure after myocardial infarction. Altered matrix metalloproteinase (MMP) activity has been implicated in the structural changes associated with development of heart ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2003.11.003

    authors: Squire IB,Evans J,Ng LL,Loftus IM,Thompson MM

    更新日期:2004-08-01 00:00:00

  • Atrial fibrillation impairs endothelial function of forearm vessels in humans.

    abstract:BACKGROUND:Although there have been many studies on the effects of atrial fibrillation (AF) on cardiac function, few studies have been done on its effects on endothelial function. The present study was designed to examine the effects of AF on endothelial function in human subjects. METHODS AND RESULTS:Changes in forea...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1054/jcaf.2001.22107

    authors: Takahashi N,Ishibashi Y,Shimada T,Sakane T,Ohata S,Sugamori T,Ohta Y,Inoue S,Nakamura K,Shimizu H,Katoh H,Sano K,Murakami Y,Hashimoto M

    更新日期:2001-03-01 00:00:00

  • Coronary hemodynamics in heart failure and effects of therapeutic interventions.

    abstract:BACKGROUND:The abnormalities in coronary hemodynamics in systolic heart failure are frequent. Myocardial oxygen demand and consumption are increased and myocardial perfusion is also impaired, which may result in myocardial ischemia, necrosis, and apoptosis. This is potentially a contributing factor for progressive hear...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,评审

    doi:10.1016/j.cardfail.2009.01.001

    authors: Chatterjee K

    更新日期:2009-03-01 00:00:00

  • Baseline Characteristics Predict the Presence of Amyloid on Endomyocardial Biopsy.

    abstract:BACKGROUND:Recent studies have suggested a high prevalence of cardiac amyloidosis (CAm) in heart failure (HF) patients. CAm might be underdiagnosed owing to low clinical suspicion. METHODS AND RESULTS:We performed retrospective analysis of 259 patients with HF and ejection fraction (EF) ≥50% referred for endomyocardia...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2016.12.006

    authors: Ton VK,Bhonsale A,Gilotra NA,Halushka MK,Steenbergen C,Almansa J,Brown E,Tedford RJ,Wittstein I,Sharma K,Russell SD,Judge DP

    更新日期:2017-04-01 00:00:00

  • Hemodynamic ranges during daily activities and exercise testing in patients with pulmonary arterial hypertension.

    abstract:BACKGROUND:In patients with pulmonary arterial hypertension (PAH) the relationship between hemodynamic impairment experienced during daily activity and that during exercise testing is not known. METHODS AND RESULTS:Ten PAH patients received an implantable hemodynamic monitor that continuously recorded and stored right...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2014.04.019

    authors: Kjellström B,Frantz RP,Benza RL,Bennett T,Bourge RC,McGoon MD

    更新日期:2014-07-01 00:00:00

  • Dietary sodium adherence is poor in chronic heart failure patients.

    abstract:BACKGROUND:We sought to determine the rates and predictors of dietary sodium restriction and to evaluate the reliability of 24-hour urine collection as a tool to estimate dietary sodium intake in heart failure (HF) patients. METHODS AND RESULTS:We evaluated the 24-hour urinary sodium excretion of 305 outpatients with ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.cardfail.2014.12.016

    authors: Basuray A,Dolansky M,Josephson R,Sattar A,Grady EM,Vehovec A,Gunstad J,Redle J,Fang J,Hughes JW

    更新日期:2015-04-01 00:00:00

  • Relevance of water gymnastics in rehabilitation programs in patients with chronic heart failure or coronary artery disease with normal left ventricular function.

    abstract:BACKGROUND:Exercise training is included in cardiac rehabilitation programs to enhance physical capacity and cardiovascular function. Among the existing rehabilitation programs, exercises in water are increasingly prescribed. However, it has been questioned whether exercises in water are safe and relevant in patients w...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.cardfail.2011.04.008

    authors: Teffaha D,Mourot L,Vernochet P,Ounissi F,Regnard J,Monpère C,Dugué B

    更新日期:2011-08-01 00:00:00

  • Decreases in daily physical activity predict acute decline in attention and executive function in heart failure.

    abstract:BACKGROUND:Reduced physical activity (PA) may be one factor that contributes to cognitive decline and dementia in heart failure (HF). Yet, the longitudinal relationship between PA and cognition in HF is poorly understood owing to limitations of past work, including single-time assessments of PA. This is the first study...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.cardfail.2014.12.010

    authors: Alosco ML,Spitznagel MB,Cohen R,Sweet LH,Hayes SM,Josephson R,Hughes J,Gunstad J

    更新日期:2015-04-01 00:00:00

  • Lower Extremity Function Is Independently Associated With Hospitalization Burden in Heart Failure With Preserved Ejection Fraction.

    abstract:BACKGROUND:Frailty reflects decreased resilience to physiological stressors; its prevalence and prognosis are not fully defined in heart failure with preserved ejection fraction (HFpEF). METHODS:The Short Physical Performance Battery (SPPB) was prospectively obtained in 114 outpatients with HFpEF. The SPPB tests gait ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2018.09.002

    authors: Hornsby WE,Sareini MA,Golbus JR,Willer CJ,McNamara JL,Konerman MC,Hummel SL

    更新日期:2019-01-01 00:00:00

  • Outcomes of volume-overloaded cardiovascular patients treated with ultrafiltration.

    abstract:BACKGROUND:Ultrafiltration (UF) can rapidly and predictably remove extracellular and intravascular fluid volume. To date, assessment of UF in patients with cardiovascular disease has been confined to short- and medium-term studies in patients with a principal diagnosis of acute heart failure. METHODS:In-hospital and l...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2008.02.003

    authors: Jaski BE,Romeo A,Ortiz B,Hoagland PM,Stone M,Glaser D,Thomas L,Walsh C,Smith SC Jr

    更新日期:2008-08-01 00:00:00

  • Effect of cardiac resynchronization therapy on left ventricular diastolic function: implications for clinical outcome.

    abstract:BACKGROUND:The definition of response to cardiac resynchronization therapy (CRT) remains controversial, with variable rates of response depending on the criteria used. Our aim was to analyze the impact of CRT on diastolic function in different degrees of response, particularly in patients with positive clinical but no ...

    journal_title:Journal of cardiac failure

    pub_type: 更正并重新发布的文章,杂志文章

    doi:10.1016/j.cardfail.2013.11.001

    authors: Doltra A,Bijnens B,Tolosana JM,Gabrielli L,Castel MÁ,Berruezo A,Brugada J,Mont L,Sitges M

    更新日期:2013-12-01 00:00:00

  • Effect of intravenous immunoglobulin for fulminant myocarditis on in-hospital mortality: propensity score analyses.

    abstract:BACKGROUND:Fulminant myocarditis (FM) is a rare but life-threatening disease. Intravenous immunoglobulin (IVIG) is not recommended for acute or chronic myocarditis in Western nations owing to the lack of rigorous evidence, but it is widely used in other countries, including Japan. This nationwide retrospective cohort s...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2015.01.004

    authors: Isogai T,Yasunaga H,Matsui H,Tanaka H,Horiguchi H,Fushimi K

    更新日期:2015-05-01 00:00:00

  • Presence of autoantibody directed against β1-adrenergic receptors is associated with amelioration of cardiac function in response to carvedilol: Japanese Chronic Heart Failure (J-CHF) Study.

    abstract:BACKGROUND:Autoantibody against β1-adrenergic receptors (β1-AAb) exerts agonist-like action inducing receptor uncoupling and myocardial damage. We attempted to determine the significance of β1-AAb in chronic heart failure (CHF) patients who received carvedilol in a substudy of the Japanese Chronic Heart Failure study. ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.cardfail.2014.12.005

    authors: Nagatomo Y,Yoshikawa T,Okamoto H,Kitabatake A,Hori M,Japanese Chronic Heart Failure Study Investigators.

    更新日期:2015-03-01 00:00:00

  • Impact of dopamine infusion on renal function in hospitalized heart failure patients: results of the Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial.

    abstract:BACKGROUND:Worsening renal function (WRF) and hypokalemia related to diuretic use for acute decompensated heart failure (ADHF) are common and associated with poor prognosis. Low-dose dopamine infusion improves renal perfusion; its effect on diuresis or renal function specifically in ADHF is not known. METHODS AND RESU...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.cardfail.2010.07.246

    authors: Giamouzis G,Butler J,Starling RC,Karayannis G,Nastas J,Parisis C,Rovithis D,Economou D,Savvatis K,Kirlidis T,Tsaknakis T,Skoularigis J,Westermann D,Tschöpe C,Triposkiadis F

    更新日期:2010-12-01 00:00:00

  • Prolonged electrocardiogram QRS duration independently predicts long-term mortality in patients hospitalized for heart failure with preserved systolic function.

    abstract:BACKGROUND:Prolonged electrocardiogram (ECG) QRS duration (>or=120 ms) is a risk factor for death in systolic heart failure, but its effects in heart failure with preserved systolic function (HFPSF) have not been extensively studied. We hypothesized that prolonged ECG QRS duration would independently predict long-term ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.cardfail.2009.02.002

    authors: Hummel SL,Skorcz S,Koelling TM

    更新日期:2009-09-01 00:00:00

  • Comparison of perfusion-metabolism mismatch in 99mTc-MIBI and 123I-BMIPP scintigraphy with cardiac magnetic resonance in patients with dilated cardiomyopathy.

    abstract:BACKGROUND:Cardiac magnetic resonance (CMR) imaging is an established method of detecting myocardial fibrosis related to prognosis in patients with dilated cardiomyopathy (DCM). Recent studies have found that (99m)Tc-methoxy-isobutyl-isonitrile (MIBI) and (123)I-15-(p-iodophenyl)-3(R,S)-methylpentadecanoic acid (BMIPP)...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2013.05.009

    authors: Yoshida A,Takano H,Asai K,Yasutake M,Amano Y,Kumita S,Shimizu W,Mizuno K

    更新日期:2013-07-01 00:00:00

  • Simultaneous right atrioventricular pacing: a novel model to study atrial remodeling and fibrillation in the setting of heart failure.

    abstract:BACKGROUND:Atrial fibrillation (AF) is a common arrhythmia which contributes to morbidity and mortality in patients with heart failure (HF). Atrial remodeling is a key substrate for the development of AF in HF. However, experimental models that study AF in the setting of HF have important limitations. We evaluated a ne...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2007.10.021

    authors: Laurent G,Moe GW,Hu X,Pui-Sze So P,Ramadeen A,Leong-Poi H,Doumanovskaia L,Konig A,Trogadis J,Courtman D,Strauss BH,Dorian P

    更新日期:2008-04-01 00:00:00