Abstract：
OBJECTIVES:Proanthocyanidins (PACs) are biocompounds mimicking native collagen cross-links. The effective and practical delivery of any biocompound is pivotal for clinical usage. The aim was to investigate the dentin biomodification and effective formation of dentin-resin biointerfaces of two highly bioactive PAC-rich extracts, Vitis vinifera (Vv) and Camellia sinensis (Cs), delivered using neutral (NP) or acidic (AP) rinse-out primer approaches. METHODS:The depth of dentin demineralization (optical profilometry), dentin biomodification (apparent modulus of elasticity, collagen auto-fluorescence) and properties of dentin-resin interfaces (microtensile bond strength - μTBS, and micro-permeability) were investigated. NP consisted of either 15% Vv or Cs applied for 60 s after surface etching; while AP contained 15% Vv or Cs in either 35% glycolic acid or tartaric acid applied for 30 s or 60 s. Data were analyzed using ANOVA and post-hoc tests (α = 0.05). RESULTS:The depth of demineralization was statistically higher when applied for 60 s, regardless of rinse-out primer approach (p < 0.001). Compared to the AP strategy, NP exhibited statistically higher apparent modulus of elasticity, regardless of PAC extract (p < 0.001). Highest μTBS were obtained for NPVv, which were statistically similar to APGAVv, when applied for 60 s (p < 0.001); both resulted in a dramatic decrease of the interfacial permeability. NPCs group showed the lowest μTBS (p < 0.001). CONCLUSIONS:A combination of high bond strength and low micro-permeability can be accomplished using glycolic acid with the mid- and high-PAC oligomer enriched extract (Vv). Cs extract containing mostly catechins and dimeric PACs, was found unsuitable for resin-dentin adhesion despite exhibiting high initial dentin biomodification. CLINICAL SIGNIFICANCE:This study provides a new conceptual delivery of PAC-mediated dentin biomodification and conservative dentin surface etching using rinse-out primers. The strategy requires a specific combination of PAC source, α-hydroxy acid, and application time.
journal_name
J Dentjournal_title
Journal of dentistryauthors
Trevelin LT,Alania Y,Mathew M,Phansalkar R,Chen SN,Pauli GF,Bedran-Russo AKdoi
10.1016/j.jdent.2020.103354subject
Has Abstractpub_date
2020-08-01 00:00:00pages
103354eissn
0300-5712issn
1879-176Xpii
S0300-5712(20)30096-8journal_volume
99pub_type
杂志文章abstract：OBJECTIVE:The aim of this study was to compare the behavior of two new, low-shrinkage hybrid composites (Aelite LS and Inten-S) with a microfilled (Heliomolar) and a hybrid composite (Filtek Z250), in terms of polymerization contraction stress and microleakage. METHODS:Maximum contraction stress after 10 min was recor...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2004.01.014
更新日期：2004-07-01 00:00:00
abstract：OBJECTIVES:To elucidate the impact of surface properties and the release of fluoride from different glass ionomer cements on biofilm formation. METHODS:Standardized specimens manufactured from various classes of glass ionomer cements (GICs), a resin-based composite (RBC), and human enamel were subjected to surface ana...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2017.02.005
更新日期：2017-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of compounds of Galla chinensis on the remineralisation of initial enamel carious lesions in vitro. METHODS:Sixty bovine enamel blocks with early lesions were prepared and randomly divided into six treatment groups. The lesions were subjected to a pH-cycling regime for 12 days. Each da...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2006.11.007
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVES:This clinical study evaluated the long-term outcome and survival rate of all-ceramic cantilever resin-bonded fixed dental prostheses (RBFDPs) made of zirconia-ceramic with a single-retainer design to replace missing incisors. In addition, whether the reason for missing incisors has an influence on the longev...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2017.07.003
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVE:An accurate evaluation of the extent of dental caries and possible progress of the lesion from enamel into dentin is very important in clinical dentistry. Dentists need an imaging technology that can noninvasively and reliably quantify the extent of caries. This study aimed to evaluate the effectiveness of no...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2012.10.007
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:To analyse smear layers on human dentine using ac-impedance spectroscopy. METHODS:Dentine samples were prepared from extracted, sound, third molars. Impedance measurements were carried out on dentine samples before and after etching. After measuring, samples were examined under scanning electron microscope (...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2004.05.003
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVES:This clinical follow-up evaluated the long-term outcome of full-mouth rehabilitations with adhesively bonded all-ceramic restorations in patients suffering from amelogenesis imperfecta (AI) or affected by extensive tooth wear including a loss of the vertical dimension of occlusion. MATERIALS AND METHODS:Inc...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2017.12.011
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVES:Small and hydrophilic monomers as HEMA and TEGDMA can easily penetrate human tissues. For biocompatibility issues it is therefore better to avoid such monomers in dental adhesive formulations. The purpose of this study was (1) to determine the micro-tensile bond strength (muTBS) to enamel/dentin of a HEMA/TE...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2008.05.012
更新日期：2008-10-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to test the hypothesis that cross-polarization optical coherence tomography (CP-OCT) can be used to longitudinally monitor demineralization peripheral to orthodontic brackets in an extended clinical study. METHODS:A high-speed CP-OCT system was used to acquire 3D volumetric images ...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdent.2014.02.011
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:To analyse the DIAGNOdent's performance to longitudinally monitor the arrestment of non-cavitated carious lesions in occlusal surfaces. METHODS:The sample consisted of 15 children (12-13 years old) with 40 active non-cavitated lesions. The protocol for the examinations was: prophylaxis, drying teeth for 30s;...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2007.05.005
更新日期：2007-08-01 00:00:00
abstract：OBJECTIVES:Recently, a novel device to generate dental plaque in situ on a removable human enamel surface was described. The device permitted the recovery of plaque intact and undisturbed on its enamel substrate. The aim of this investigation was to determine the utility and robustness of this model for analysis of the...
journal_title：Journal of dentistry
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0300-5712(01)00033-1
更新日期：2001-08-01 00:00:00
abstract：OBJECTIVE:The present study tested the central hypothesis that selective demineralisation of dentine extrafibrillar minerals by lowering the phosphoric acid concentration improves the quality of the resin-dentine interface. METHODS:Dentine surfaces were etched with different concentrations of phosphoric acid (1, 5, 10...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2016.07.008
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVES:Manufacturers are adding fluoride (F) to calcium-containing chewing gums to further promote enamel remineralization. The aim of this study was to assess the effect of a chewing gum containing phosphoryl oligosaccharides of calcium (POs-Ca) and fluoride on remineralization of enamel subsurface lesions, in a d...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdent.2011.08.009
更新日期：2011-11-01 00:00:00
abstract：UNLABELLED:Soy beverages are water extracts of whole soybeans and are often promoted as a healthy alternative to bovine milk. Little analysis has been carried out to determine the effects of soy beverages on oral health, especially their potential acidogenicity. OBJECTIVES:The aim of this study was to determine the po...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2012.05.004
更新日期：2012-09-01 00:00:00
abstract：OBJECTIVES:To evaluate the effect of addition of zinc oxide and copper nanoparticles (ZnO/CuNp) into universal adhesives, on antimicrobial activity (AMA), cytotoxicity (CTX), water sorption (WS) and solubility (SO), microhardness (MH) and in vitro degree of conversion (DC), as well as resin-dentin microtensile bond str...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2019.01.012
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVES:The purpose of the study was to investigate the correlation between fit accuracy and fracture resistance of zirconia abutments, as well as its feasibility for clinical applications. METHODS:Twenty self-made zirconia abutments were tested with 30 Osstem GSII implants. First, 10 Osstem GSII implants were cut ...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2014.02.008
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVES:To investigate, in a sample of probable sleep bruxers with and without temporomandibular disorder (TMD) pain, the presence and relationships between clinical jaw-muscle symptoms, and test their associations with jaw-muscle electromyographic (EMG) activity during sleep. METHODS:Pain, unpleasantness, tirednes...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2019.05.016
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVES:To evaluate the toothbrush wear resistance of infiltrated artificial white spot lesions following two infiltration strategies, and to assess their ultramorphology. METHODS:Flat enamel surfaces from freshly extracted bovine teeth were polished and immersed in a Buskes demineralising solution for 30 days to c...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2011.02.009
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVE:To determine the influence of hard and soft splints with two thicknesses on the stress transmission to the tooth supporting the splint and the opposite tooth. METHODS:Continuous vertical forces up to 500N were applied to two opposite first molar phantom teeth using a universal loading machine. Deformation wa...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(00)00026-9
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVES:This study aimed to evaluate posterior restorations placed in young adults, investigating the association between social determinants experienced during the life course and the quality of tooth fillings. METHODS:A representative sample (n=720) of all 5914 individuals who were born in Pelotas in 1982 was pro...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2013.02.010
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVES:A low pH environment is created by cariogenic bacteria. This study was aimed to measure pH of carious lesions intraorally using a micro-pH sensor, and assess predominant acid-producing cariogens by qPCR to differentiate caries activities. METHODS:103 dentine lesions classified as active or arrested caries b...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2011.12.013
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to examine the behavior of posterior teeth restored with single-tooth restorations with intentionally high occlusal contacts. METHODS:Consent was obtained from 17 patients who were seen a total of 5 times over 3.5 years. The restorations placed were all full occlusal coverage gold r...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdent.2015.11.006
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVES:Dentifrices containing zinc reduce gingival inflammation and bleeding better than control dentifrices (no zinc). How zinc might work is not understood. We have shown that lysine decarboxylase (LdcE), an enzyme from Eikenella corrodens, converts lysine to cadaverine in dental biofilms. The lack of lysine impa...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2020.103533
更新日期：2020-11-12 00:00:00
abstract：OBJECTIVES:The main objective is the characterisation of the setting reaction in glass ionomer cements based on experimental ionomer glasses with different fluorine content and a commercial glass ionomer cement liquid by using 13C CP/MAS-NMR, 29Si, 27Al and 31P MAS-NMR spectroscopy in order to receive information speci...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2005.08.006
更新日期：2006-09-01 00:00:00
abstract：:The head of a university, especially of a research university, expects a great deal from the dean, and the dean's team, of a dental school. These leaders have to balance an especially complex set of tasks and, in the process, pursue maximum integration into their university. Dental deans should aspire to be at least e...
journal_title：Journal of dentistry
pub_type： 杂志文章,评审
doi：10.1016/j.jdent.2019.05.003
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVES:To investigate in vitro a range of differently characterised toothpastes with respect to their efficacy in an erosion/abrasion setting with special emphasis on the role of the particulate ingredients. METHODS:Human enamel samples were erosively demineralised with citric acid (2min, 6×/day; 0.5%, pH 2.5; 10 ...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2016.09.005
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVES:This prospective clinical study compared the performance of implant-retained (study group) and tooth-retained (control) zirconia based fixed dental prostheses (FDPs) with at least 4 units. The null-hypothesis stated that complication rates in both groups are equally distributed. METHODS:The study included p...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2014.10.011
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:Three luting cements based on zinc oxide phosphate, glass ionomer or composite resin were compared with respect to their influence on the anaerobic fermentation of sucrose by human oral bacteria. METHODS:Fifteen standardized samples of each of the three luting cements were prepared according to the manufact...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(98)00027-x
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the microtensile bond strengths of total etching adhesive systems to pulpal chamber wall dentine after treated with various irrigants. METHODS:Thirty extracted human third molars were cut horizontally to expose the pulp horn. The roof of the pulp chamber and pulp ti...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2005.01.008
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to determine whether conventional black tea and a herbal tea were capable of eroding dental enamel. A further aim was to investigate whether herbal tea of the type tested eroded dental hard tissues to a greater or lesser extent than conventional black tea. METHODS:Three groups of 2...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(01)00044-6
更新日期：2001-11-01 00:00:00
