Preoperative anaemia and thrombocytopenia are associated with venous thromboembolism complications after colorectal resection.

Abstract:

BACKGROUND:Earlier studies have shown that abnormal levels of haemoglobin and platelets may be associated with worse post-operative outcomes. We aim to compare the rates of venous thromboembolism (VTE), anastomotic leak and other complications in patients post-colorectal resection with normal and abnormal levels of haemoglobin and platelets. METHODS:We performed a retrospective review of 1610 patients from July 2010 to June 2015 in a single colorectal unit. Our primary outcome was the rate of VTE and anastomotic leak in anaemic and thrombocytopenic patients. Secondary outcomes included length of stay, 30-day mortality, return to theatre, transfusion rates and Clavien-Dindo classification complications. RESULTS:VTE complications were more common in anaemic patients, and this difference became more pronounced with the severity of anaemia. Other complications such as length of stay >2 weeks occurred more frequently in anaemic and thrombocytopenic patients. A trend towards higher rates of 30-day mortality and anastomotic leak was noted in patients with anaemia and thrombocytopenia. CONCLUSION:Anaemia and thrombocytopenia are associated with worse outcomes including length of stay, anastomotic leak, VTE and 30-day mortality.

journal_name

ANZ J Surg

journal_title

ANZ journal of surgery

authors

Yeap E,Teoh WMK,Nguyen TC,Suhardja TS

doi

10.1111/ans.15918

subject

Has Abstract

pub_date

2020-05-01 00:00:00

eissn

1445-1433

issn

1445-2197

pub_type

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