Abstract:
:The study and applications of in vivo skin optics have been openly documented as early as the year 1954, or possibly earlier. To date, challenges in analyzing the complexities of this field remain, with wide scopes requiring more scrutiny. Recent advances in spectroscopic research and multivariate analytics allow a closer look into applications potentially for detecting or monitoring diseases. One of the challenges in this field is in establishing a reference for applications which correspond to certain bandwidths. This article reviews the scope on past research on skin spectroscopy, and the clinical aspects which have or may have applications on disease detection or enhancing diagnostics. A summary is supplied on the technicalities surrounding the measurements reported in literature, focused towards the wavelength-dependent applications in themes central to the respective research. Analytics on the topology of the papers' data cited in this work is also provided for a statistical perspective. In short, this paper strives to immediately inform the reader with possible applications via the spectroscopic devices at hand. Graphical Abstract .
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Poh AH,Adikan FRM,Moghavvemi Mdoi
10.1007/s11517-019-02077-9subject
Has Abstractpub_date
2020-06-01 00:00:00pages
1159-1175issue
6eissn
0140-0118issn
1741-0444pii
10.1007/s11517-019-02077-9journal_volume
58pub_type
杂志文章,评审abstract::In this study, we introduce a novel simulation technique to incorporate delineation errors into radiotherapy treatment margins and combine them with organ motion and set-up errors to investigate the cumulative dosimetric effects in different tumour sites. The effects of applying patient realignment correction protocol...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-010-0616-z
更新日期:2010-07-01 00:00:00
abstract::Past decades witnessed the expansion of linear signal processing methods in numerous biomedical applications. However, the nonlinear behavior of biomedical signals revived the interest in nonlinear signal processing methods such as higher-order statistics, in particular higher-order cumulants (HOC). In this paper, HOC...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-015-1394-4
更新日期:2015-11-01 00:00:00
abstract::There is a lack of information regarding the forces required for suturing human wounds. The knowledge of suturing forces serves as complementary information for setting up the limiting geometry when using tissue adhesives and it might also be used in robot-assisted surgery. The main purpose of this paper was to evalua...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-011-0857-5
更新日期:2012-02-01 00:00:00
abstract::A system, to collect, analyse and display biological data, is developed using IBM PC AT compatibles (PCs) or CED1401/1609 devices networked to a VAX environment. It can be operated in three separate modes: using the CED/IEEE/VAX network; using the PC/Ethernet/VAX network; as a standalone PC. The original system compri...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02446881
更新日期:1993-01-01 00:00:00
abstract::The Pennes bioheat equation and finite element method (FEM) are used to solve for the temperature distributions in the spinal cord and cerebrospinal fluid (CSF) during 30 min of cooling for spinal cord injury (SCI) patients. The average CSF and spinal cord temperatures are reduced by 3.48 and 2.72 degrees C, respectiv...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-009-0543-z
更新日期:2010-02-01 00:00:00
abstract::The first in vivo evaluation of a pO2 sensor constructed with a novel copolymer is described. The performance of the sensor is assessed under dynamic conditions in vitro and in vivo. This sensor is more stable and reliable than the control sensor with a heparin-treated polyethylene membrane. ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02511245
更新日期:1996-07-01 00:00:00
abstract::Tooth mobility examination is important in planning dental treatment, as it may give an indication of alveolar bone loss and the condition of the periodontal ligament. In clinical dental diagnosis a manual tooth mobility examination is useful. However, its determination of tooth mobility is subjective and depends on t...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02442173
更新日期:1989-01-01 00:00:00
abstract::Using images from the Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI), we developed a methodology for classifying lung nodules. The proposed methodology uses image processing and pattern recognition techniques. To classify volumes of interest into nodules and non-nodules, we used shape mea...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1582-x
更新日期:2017-08-01 00:00:00
abstract::Stroke survivors are more prone to developing cognitive impairment and dementia. Dementia detection is a challenge for supporting personalized healthcare. This study analyzes the electroencephalogram (EEG) background activity of 5 vascular dementia (VaD) patients, 15 stroke-related patients with mild cognitive impairm...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-017-1734-7
更新日期:2018-01-01 00:00:00
abstract::While matrix remodeling plays a key role in vascular physiology and pathology, the underlying mechanisms have remained incompletely understood. We studied the remodeling of collagen matrices by individual vascular smooth muscle cells (SMCs), clusters and monolayers. In addition, we focused on the contribution of trans...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-012-0916-6
更新日期:2012-07-01 00:00:00
abstract::The development of computer technology now allows the quick and efficient automatic fluorescence microscopy generation of a large number of images of proteins in specific subcellular compartments using fluorescence microscopy. Digital image processing and pattern recognition technology can easily classify these images...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-018-01946-z
更新日期:2019-06-01 00:00:00
abstract::Long periods of bed rest negatively affect the human body organs, notably the cardiovascular system. To avert these negative effects and promote functional recovery in patients dealing with prolonged bed rest, the goal is to mobilize them as early as possible while controlling and stabilizing their cardiovascular syst...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-017-1628-8
更新日期:2017-09-01 00:00:00
abstract::Classification of cancerous genes from microarray data is an important research area in bioinformatics. Large amount of microarray data are available, but it is very costly to label them. This paper proposes an active learning model, a semi-supervised classification approach, to label the microarray data using which p...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02238-1
更新日期:2020-10-01 00:00:00
abstract::Most tissues are subject to some form of physiological mechanical loading which results in deformation of the cells triggering intracellular mechanotransduction pathways. This response to loading is generally essential for the health of the tissue, although more pronounced deformation may result in cell and tissue dam...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章,评审
doi:10.1007/s11517-008-0381-4
更新日期:2008-10-01 00:00:00
abstract::A new technique is derived for estimating the conduction velocity of muscle fibre action potentials from surface EMG recordings in humans. The method is based on system identification and extends previous such methods by explicitly accounting for additive noise at the output as well as at the input. Experimental and s...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02446220
更新日期:1989-03-01 00:00:00
abstract::The visco-elastic properties of living cells, measured to date by various authors, vary considerably, depending on the experimental methods and/or on the theoretical models used. In the present study, two mechanisms thought to be involved in cellular visco-elastic responses were analysed, based on the idea that the cy...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02349982
更新日期:2003-11-01 00:00:00
abstract::The reconstruction of bioluminescence tomography (BLT) is severely ill-posed due to the insufficient measurements and diffuses nature of the light propagation. Predefined permissible source region (PSR) combined with regularization terms is one common strategy to reduce such ill-posedness. However, the region of PSR i...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-018-1842-z
更新日期:2018-11-01 00:00:00
abstract::Magnetic nanoparticles for therapy and diagnosis are at the leading edge of the rapidly developing field of bionanotechnology. In this study, we have theoretically studied motion of magnetic nano- as well as micro-particles in the field of cylindrical Halbach array of permanent magnets. Magnetic flux density was model...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-010-0636-8
更新日期:2010-08-01 00:00:00
abstract::We present a new, automatic, correlation-based method for measuring the duration of motor unit action potentials (MUAPs). The method seeks to replicate the way an expert elctromyographer uses his or her eyes, calculating the start and end of the MUAP waveform on the basis of the degree of similarity of non-excluded di...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-019-02115-6
更新日期:2020-03-01 00:00:00
abstract::This work addresses the problem of estimating the conduction velocity (CV) of single motor unit (MU) action potentials from surface EMG signals detected with linear electrode arrays during voluntary muscle contractions. In ideal conditions, that is without shape or scale changes of the propagating signals and with add...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02344807
更新日期:2001-03-01 00:00:00
abstract::In total hip arthroplasty, determining the impingement free range of motion requirement is a complex task. This is because in the native hip, motion is restricted by both impingement as well as soft tissue restraint. The aim of this study is to determine a range of motion benchmark which can identify motions which are...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-012-1016-3
更新日期:2013-04-01 00:00:00
abstract::To describe the spatial and temporal profiles of connectivity networks and sources preceding generalized spike-and-wave discharges (SWDs) in human absence epilepsy. Nonlinear associations of MEG signals and cluster indices obtained within the framework of graph theory were determined, while source localization in the ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-011-0778-3
更新日期:2011-05-01 00:00:00
abstract::In a computerised ultrasound image guidance for automated prostatectomy system, it is necessary to identify a smooth, continuous contour for the prostate (boundary) from the ultrasound image. The radial bas-relief (RBR) method, which has been reported previously, can extract a skeletonised image from an ultrasound ima...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02518882
更新日期:1998-11-01 00:00:00
abstract::A biphasic continuum model for the flow of intraocular fluid, the aqueous humour, in the trabecular meshwork is proposed in the paper. The model considers the meshwork as a circular ring with uniform thickness of homogeneous, isotropic, viscoelastic material swollen with continuously percolating aqueous humour. The mo...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02446710
更新日期:1991-05-01 00:00:00
abstract::The purpose of this study is to verify the applicability of a sixth-order model to the mechanomyogram (MMG) system of the parallel-fibered muscle, which was identified from the MMG of the pennation muscle. The median nerve was stimulated, and an MMG and torque of the abductor pollicis brevis muscle were measured. The ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-013-1107-9
更新日期:2013-12-01 00:00:00
abstract::Vascular access for renal dialysis is a lifeline for about 120 000 individuals in the United States. Stethoscope auscultation of vascular sounds has some utility in the assessment of access patency, yet can be highly skill-dependent. The objective of the study was to identify acoustic parameters that are related to ch...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345123
更新日期:2005-01-01 00:00:00
abstract::The diagnosis of sleep-disordered breathing (SDB) usually relies on the analysis of complex polysomnographic measurements performed in specialized sleep centers. Automatic signal analysis is a promising approach to reduce the diagnostic effort. This paper addresses SDB and sleep assessment solely based on the analysis...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-011-0853-9
更新日期:2012-02-01 00:00:00
abstract::Computer-based simulations of human hip joints generally include investigating contacts happening among soft or hard tissues during hip movement. In many cases, hip movement is approximated as rotation about an estimated hip center. In this paper, we investigate the effect of different methods used for estimating hip ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-012-0873-0
更新日期:2012-06-01 00:00:00
abstract::Preprocessing, binning and dataset subsampling are investigated with regard to simultaneous maximisation of the speed, accuracy and robustness of CT-3D rotational angiography (3DRA) registration. Clinical diagnosis and treatment can both take advantage of this integration, because 3DRA allows the shape of vessel struc...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02351041
更新日期:2005-09-01 00:00:00
abstract::Conduct disorder (CD) is an important mental health problem in childhood and adolescence. There is presently a trend of revealing neural mechanisms using measures of brain networks. This study goes further by presenting a classification scheme to distinguish subjects with CD from typically developing healthy subjects ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02215-8
更新日期:2020-09-01 00:00:00