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The efficacy of dexamethasone on pain management for knee arthroscopy: A meta-analysis of randomized controlled trials.

Abstract：

INTRODUCTION:The impact of dexamethasone on pain management for knee arthroscopy remains controversial. We conduct a systematic review and meta-analysis to explore the influence of dexamethasone for knee arthroscopy. METHODS:We search PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases through October 2018 for randomized controlled trials (RCTs) assessing the effect of dexamethasone on pain intensity for patients with dental implant. This meta-analysis is performed using the random-effect model. RESULTS:Four RCTs involving 228 patients are included in the meta-analysis. Overall, compared with control group for knee arthroscopy, dexamethasone supplementation has no notable effect on pain scores at 4 to 6 hours (Std. MD = 0.99; 95% CI = -2.97 to 4.95; P = .62), but exerts significantly favorable promotion to pain scores at 12 hours (Std. MD = -1.06; 95% CI = -1.43 to -0.69; P < .00001), duration of block (Std. MD = 1.87; 95% CI = 0.65 to 3.10; P = .003), time to first analgesic requirement (Std. MD = 0.90; 95% CI = 0.51 to 1.29; P < .00001), analgesic consumption (Std. MD = -1.62; 95% CI = -2.31 to -0.93; P < .00001), and patient satisfaction (Std. MD = 1.15; 95% CI = 0.73 to 1.58; P < .00001). CONCLUSIONS:Dexamethasone supplementation has importantly positive influence on pain control for knee arthroscopy.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Peng C,Li C,Yuan B,Jiao J

doi

10.1097/MD.0000000000019417

subject

Has Abstract

pub_date

2020-04-01 00:00:00

pages

e19417

issue

16

eissn

0025-7974

issn

1536-5964

pii

00005792-202004170-00004

journal_volume

99

pub_type

杂志文章,meta分析

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